CL2023002744A1 - Métodos de producción de células que expresan receptores de antígeno quiméricos - Google Patents

Métodos de producción de células que expresan receptores de antígeno quiméricos

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Publication number
CL2023002744A1
CL2023002744A1 CL2023002744A CL2023002744A CL2023002744A1 CL 2023002744 A1 CL2023002744 A1 CL 2023002744A1 CL 2023002744 A CL2023002744 A CL 2023002744A CL 2023002744 A CL2023002744 A CL 2023002744A CL 2023002744 A1 CL2023002744 A1 CL 2023002744A1
Authority
CL
Chile
Prior art keywords
methods
chimeric antigen
cells expressing
producing cells
antigen receptors
Prior art date
Application number
CL2023002744A
Other languages
English (en)
Inventor
Brogdon Jennifer
Dranoff Glenn
Hack Anniesha
Kodrasi Olja
Price Andrew
Bondanza Attilio
ENGELS Boris
Lim Hyungwook
Sohoni Akash
Treanor Louise
Zhu Xu
Patricia Pinto Guimaraes Carla
Sharma Sujata
R Greene Michael
Carbonneau Seth
Horst Peter Hild Marc
Marc Stein Andrew
Dorothy Pratico Elizabeth
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of CL2023002744A1 publication Critical patent/CL2023002744A1/es

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
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Abstract

La presente divulgación proporciona métodos para producir células efectoras inmunitarias (por ejemplo, células T, células NK) que comprenden (i) una molécula de ácido nucleico que codifica un receptor de antígeno quimérico controlable (CCAR) o (ii) una molécula de ácido nucleico que codifica un CAR y una molécula reguladora, y composiciones generadas por dichos métodos.
CL2023002744A 2020-02-27 2023-09-14 Métodos de producción de células que expresan receptores de antígeno quiméricos CL2023002744A1 (es)

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