RU95114532A - Устройство для распыления лекарственного средства в форме порошка - Google Patents
Устройство для распыления лекарственного средства в форме порошкаInfo
- Publication number
- RU95114532A RU95114532A RU95114532/14A RU95114532A RU95114532A RU 95114532 A RU95114532 A RU 95114532A RU 95114532/14 A RU95114532/14 A RU 95114532/14A RU 95114532 A RU95114532 A RU 95114532A RU 95114532 A RU95114532 A RU 95114532A
- Authority
- RU
- Russia
- Prior art keywords
- chamber
- impeller
- spray chamber
- housing
- wall
- Prior art date
Links
- 239000003814 drug Substances 0.000 title claims 2
- 229940079593 drugs Drugs 0.000 title claims 2
- 238000005507 spraying Methods 0.000 title claims 2
- 239000007921 spray Substances 0.000 claims 8
- 239000000843 powder Substances 0.000 claims 2
Claims (11)
1. Устройство для распыления лекарственного средства в форме порошка, включающее корпус, отличающееся тем, что содержит в общем плоскую переднюю стенку камеры, в общем плоскую заднюю стенку камеры и круговую стенку камеры, расположенные в корпусе и образующие в общем дисковидной формы распылительную камеру, крыльчатку, установленную в распылительной камере и вращающуюся в плоскости, в общем параллельной передней и задней стенкам камеры, двигатель, соединенный с крыльчаткой и предназначенный для вращения крыльчатки в распылительной камере, и по меньшей мере одно впускное отверстие и по меньшей мере одно выпускное отверстие в распылительной камере.
2. Устройство по п. 1, отличающееся тем, что передняя стенка камеры отделена от задней стенки камеры расстоянием, меньшим чем один диаметр крыльчатки.
3. Устройство по п. 1, отличающееся тем, что к корпусу, включая переднюю стенку камеры, может крепиться мундштук.
4. Устройство по п. 1 или 2, отличающееся тем, что выпускное отверстие располагается рядом с круговой стенкой камеры.
5. Устройство по п. 1 или 2, отличающееся тем, что крыльчатка имеет диаметр, приблизительно в четыре раза превышающий расстояние между передней и задней стенками камеры.
6. Устройство по п. 1 или 2, отличающееся тем, что двигатель расположен вне распылительной камеры.
7. Устройство по п. 1, отличающееся тем, что содержит средства для подачи порошка в распылительную камеру.
8. Устройство по п. 1 или 2, отличающееся тем, что содержит также передний цилиндр, прикрепленный к корпусу и включающий цилиндрическую камеру, первое множество отверстий, соединяющих распылительную камеру и цилиндрическую камеру, и второе множество отверстий, направленных в радиальном направлении от переднего цилиндра.
9. Устройство по п. 1 или 2, отличающееся тем, что содержит однопутевый клапан для предупреждения выдыхания в устройство.
10. Устройство по п. 9, отличающееся тем, что содержит переключатель, включающий двигатель при открывании однопутевого клапана.
11. Устройство по пп. 1, 2 или 5, отличающееся тем, что крыльчатка плотно входит в распылительную камеру со всех сторон.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US96340992A | 1992-10-19 | 1992-10-19 | |
US07/963,409 | 1992-10-19 | ||
US07/963409 | 1992-10-19 | ||
PCT/US1993/009751 WO1994008552A2 (en) | 1992-10-19 | 1993-10-12 | Dry powder inhaler |
Publications (2)
Publication Number | Publication Date |
---|---|
RU95114532A true RU95114532A (ru) | 1997-07-27 |
RU2141849C1 RU2141849C1 (ru) | 1999-11-27 |
Family
ID=25507205
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU95114532A RU2141849C1 (ru) | 1992-10-19 | 1993-10-12 | Устройство для распыления лекарственного средства в форме порошка |
Country Status (26)
Country | Link |
---|---|
US (1) | US5577497A (ru) |
EP (1) | EP0665759B1 (ru) |
JP (1) | JP2912453B2 (ru) |
KR (1) | KR0177265B1 (ru) |
AT (1) | ATE174804T1 (ru) |
AU (1) | AU679700B2 (ru) |
BG (1) | BG61554B1 (ru) |
BR (1) | BR9307270A (ru) |
CA (1) | CA2147260C (ru) |
CZ (1) | CZ282964B6 (ru) |
DE (1) | DE69322789T2 (ru) |
DK (1) | DK0665759T3 (ru) |
ES (1) | ES2127837T3 (ru) |
FI (1) | FI951838A0 (ru) |
GR (1) | GR3029732T3 (ru) |
HK (1) | HK1013262A1 (ru) |
HU (1) | HU217917B (ru) |
NO (1) | NO311870B1 (ru) |
NZ (1) | NZ257056A (ru) |
PL (1) | PL172758B1 (ru) |
RO (1) | RO113214B1 (ru) |
RU (1) | RU2141849C1 (ru) |
SK (2) | SK279327B6 (ru) |
TW (1) | TW235245B (ru) |
UA (1) | UA27938C2 (ru) |
WO (1) | WO1994008552A2 (ru) |
Families Citing this family (214)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY105368A (en) * | 1990-03-02 | 1994-09-30 | Glaxo Group Ltd | Inhalation device. |
HU213221B (en) * | 1990-03-02 | 1997-03-28 | Glaxo Group Ltd | Inhalation device and medicine packet for device |
US6055980A (en) * | 1991-05-20 | 2000-05-02 | Dura Pharmaceuticals, Inc. | Dry powder inhaler |
US5785049A (en) * | 1994-09-21 | 1998-07-28 | Inhale Therapeutic Systems | Method and apparatus for dispersion of dry powder medicaments |
US6586006B2 (en) | 1994-08-04 | 2003-07-01 | Elan Drug Delivery Limited | Solid delivery systems for controlled release of molecules incorporated therein and methods of making same |
US6290991B1 (en) | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
NZ331353A (en) * | 1994-09-21 | 1999-07-29 | Inhale Therapeutic Syst | Apparatus and methods for dispensing dry powder medicaments |
US5780014A (en) * | 1995-04-14 | 1998-07-14 | Inhale Therapeutic Systems | Method and apparatus for pulmonary administration of dry powder alpha 1-antitrypsin |
US5645051A (en) * | 1995-04-21 | 1997-07-08 | Dura Pharmaceuticals, Inc. | Unit dose dry powder inhaler |
US5921237A (en) * | 1995-04-24 | 1999-07-13 | Dura Pharmaceuticals, Inc. | Dry powder inhaler |
US5622166A (en) * | 1995-04-24 | 1997-04-22 | Dura Pharmaceuticals, Inc. | Dry powder inhaler delivery system |
US6428771B1 (en) * | 1995-05-15 | 2002-08-06 | Pharmaceutical Discovery Corporation | Method for drug delivery to the pulmonary system |
US5669973A (en) * | 1995-06-06 | 1997-09-23 | David Sarnoff Research Center, Inc. | Apparatus for electrostatically depositing and retaining materials upon a substrate |
US5714007A (en) * | 1995-06-06 | 1998-02-03 | David Sarnoff Research Center, Inc. | Apparatus for electrostatically depositing a medicament powder upon predefined regions of a substrate |
US6672304B1 (en) | 1995-06-08 | 2004-01-06 | Innovative Devices, Llc | Inhalation actuated device for use with metered dose inhalers (MDIs) |
US20040237961A1 (en) * | 1995-06-08 | 2004-12-02 | Snow John Medlin | Inhalation actuated device for use with metered dose inhalers (MDIs) |
DE19523516C1 (de) * | 1995-06-30 | 1996-10-31 | Asta Medica Ag | Inhalator zum Verabreichen von Medikamenten aus Blisterpackungen |
US5642727A (en) * | 1995-07-25 | 1997-07-01 | David Sarnoff Research Center, Inc. | Inhaler apparatus using a tribo-electric charging technique |
US5875776A (en) * | 1996-04-09 | 1999-03-02 | Vivorx Pharmaceuticals, Inc. | Dry powder inhaler |
DK0896525T3 (da) * | 1996-04-29 | 2003-12-01 | Quadrant Technologies Ltd | Fremgangsmåder til tørpulverinhalation |
US5857456A (en) * | 1996-06-10 | 1999-01-12 | Sarnoff Corporation | Inhaler apparatus with an electronic means for enhanced release of dry powders |
US5871010A (en) | 1996-06-10 | 1999-02-16 | Sarnoff Corporation | Inhaler apparatus with modified surfaces for enhanced release of dry powders |
US5794613A (en) * | 1997-01-09 | 1998-08-18 | Sepracor, Inc. | Multiple-dose dispenser for dry powder inhalers |
TW469832U (en) | 1997-03-14 | 2001-12-21 | Astra Ab | Inhalation device |
SE9700937D0 (sv) * | 1997-03-14 | 1997-03-14 | Astra Ab | Powder inhaler I |
US6006747A (en) | 1997-03-20 | 1999-12-28 | Dura Pharmaceuticals, Inc. | Dry powder inhaler |
US20060165606A1 (en) | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
US5954047A (en) * | 1997-10-17 | 1999-09-21 | Systemic Pulmonary Development, Ltd. | Methods and apparatus for delivering aerosolized medication |
US6237591B1 (en) | 1998-11-02 | 2001-05-29 | Dura Pharmaceuticals, Inc. | Turbine dry powder inhaler |
US6116238A (en) * | 1997-12-02 | 2000-09-12 | Dura Pharmaceuticals, Inc. | Dry powder inhaler |
JP4253124B2 (ja) | 1997-12-02 | 2009-04-08 | デュラ・ファーマシューティカルズ・インコーポレイテッド | 乾燥粉末吸入器 |
US6192876B1 (en) | 1997-12-12 | 2001-02-27 | Astra Aktiebolag | Inhalation apparatus and method |
US6352722B1 (en) | 1997-12-23 | 2002-03-05 | Quadrant Holdings Cambridge Limited | Derivatized carbohydrates, compositions comprised thereof and methods of use thereof |
US6004268A (en) * | 1998-04-21 | 1999-12-21 | Addington; W. Robert | Aspiration screening process for assessing post surgery patient's risk for pneumonia |
US6257233B1 (en) | 1998-06-04 | 2001-07-10 | Inhale Therapeutic Systems | Dry powder dispersing apparatus and methods for their use |
US6149774A (en) | 1998-06-10 | 2000-11-21 | Delsys Pharmaceutical Corporation | AC waveforms biasing for bead manipulating chucks |
SE512386C2 (sv) * | 1998-07-30 | 2000-03-06 | Microdrug Ag | Förfarande och anordning för klassificering av elektrostatiskt laddat pulverformigt material |
UA73924C2 (en) | 1998-10-09 | 2005-10-17 | Nektar Therapeutics | Device for delivering active agent formulation to lungs of human patient |
FR2787031B1 (fr) * | 1998-12-11 | 2001-03-30 | Valois Sa | Dispositif d'inhalation ameliore |
CA2356637C (en) | 1998-12-22 | 2011-09-13 | The University Of North Carolina At Chapel Hill | Compounds and methods for the treatment of airway diseases and for the delivery of airway drugs |
US6923979B2 (en) * | 1999-04-27 | 2005-08-02 | Microdose Technologies, Inc. | Method for depositing particles onto a substrate using an alternating electric field |
DK2280021T3 (en) * | 1999-06-29 | 2016-05-02 | Mannkind Corp | Pharmaceutical formulations comprising insulin complexed to a diketopiperazine |
US9006175B2 (en) * | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
US7305986B1 (en) * | 1999-07-23 | 2007-12-11 | Mannkind Corporation | Unit dose capsules for use in a dry powder inhaler |
US7464706B2 (en) | 1999-07-23 | 2008-12-16 | Mannkind Corporation | Unit dose cartridge and dry powder inhaler |
US6679256B2 (en) | 1999-12-17 | 2004-01-20 | Nektar Therapeutics | Systems and methods for extracting powders from receptacles |
US6651655B1 (en) * | 2000-01-18 | 2003-11-25 | Quadrant Technologies Limited | Inhaled vaccines |
JP2003525081A (ja) | 2000-02-28 | 2003-08-26 | ヴェクチュラ リミテッド | 経口薬物の送達における改良、またはそれに関する改良 |
US20060083691A1 (en) * | 2000-05-10 | 2006-04-20 | Wermeling Daniel P | Intranasal opioid compositions, delivery devices and methods of using same |
US6948494B1 (en) * | 2000-05-10 | 2005-09-27 | Innovative Devices, Llc. | Medicament container with same side airflow inlet and outlet and method of use |
US20040115133A1 (en) * | 2000-05-10 | 2004-06-17 | Wermeling Daniel P. | Intranasal opioid compositions |
US20030003057A1 (en) * | 2000-07-07 | 2003-01-02 | Jeffry Weers | Methods for administering leuprolide by inhalation |
US7871598B1 (en) | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
US8404217B2 (en) | 2000-05-10 | 2013-03-26 | Novartis Ag | Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use |
AU6124601A (en) | 2000-05-10 | 2001-11-20 | Alliance Pharmaceutical Corporation | Phospholipid-based powders for drug delivery |
US6610271B2 (en) * | 2000-05-10 | 2003-08-26 | University Of Kentucky Research Foundation | System and method for intranasal administration of lorazepam |
TWI224515B (en) * | 2000-06-23 | 2004-12-01 | Norton Healthcare Ltd | Pre-metered dose magazine for breath-actuated dry powder inhaler |
US6902734B2 (en) | 2000-08-07 | 2005-06-07 | Centocor, Inc. | Anti-IL-12 antibodies and compositions thereof |
US7288390B2 (en) | 2000-08-07 | 2007-10-30 | Centocor, Inc. | Anti-dual integrin antibodies, compositions, methods and uses |
UA81743C2 (ru) | 2000-08-07 | 2008-02-11 | Центокор, Инк. | МОНОКЛОНАЛЬНОЕ АНТИТЕЛО ЧЕЛОВЕКА, КОТОРОЕ СПЕЦИФИЧЕСКИ СВЯЗЫВАЕТСЯ С ФАКТОРОМ НЕКРОЗА ОПУХОЛЕЙ АЛЬФА (ФНПα), ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ, КОТОРАЯ ЕГО СОДЕРЖИТ, И СПОСОБ ЛЕЧЕНИЯ РЕВМАТОИДНОГО АРТРИТА |
AU2001283546A1 (en) | 2000-08-14 | 2002-02-25 | Advanced Inhalation Research, Inc. | Inhalation device and method |
AU2001286518A1 (en) * | 2000-08-15 | 2002-02-25 | University Of Kentucky Research Foundation | Programmable multi-dose intranasal drug delivery device |
US20040176359A1 (en) * | 2001-02-20 | 2004-09-09 | University Of Kentucky Research Foundation | Intranasal Benzodiazepine compositions |
US6766799B2 (en) | 2001-04-16 | 2004-07-27 | Advanced Inhalation Research, Inc. | Inhalation device |
JP4371660B2 (ja) | 2001-04-26 | 2009-11-25 | ニユー・イングランド・フアーマシユーテイカルズ・インコーポレイテツド | 液体状および粉末状薬剤のための定量投与デバイス |
FI20011317A0 (fi) * | 2001-06-20 | 2001-06-20 | Orion Corp | Jauheinhalaattori |
JP3619176B2 (ja) * | 2001-09-14 | 2005-02-09 | オムロンヘルスケア株式会社 | エアロゾル粒子分別装置及び吸入器 |
WO2003024514A1 (en) * | 2001-09-19 | 2003-03-27 | Advent Pharmaceuticals Pty Ltd | An inhaler |
WO2003026559A2 (en) * | 2001-09-28 | 2003-04-03 | Kurve Technology, Inc | Nasal nebulizer |
MXPA04004671A (es) | 2001-11-14 | 2005-08-25 | Johnson & Johnson | Anticuerpos anti-interleucina-6, composiciones, metodos y usos. |
MXPA04005865A (es) * | 2001-12-19 | 2004-09-13 | Nektar Therapeutics | Suministro de aminoglucosidos a los pulmones. |
CA2476405C (en) | 2002-02-13 | 2011-10-11 | Immunology Laboratories, Inc. | Compositions and methods for treatment of microbial infections |
CA2479751C (en) | 2002-03-20 | 2008-06-03 | Trent Poole | Inhalation apparatus |
US7378438B2 (en) * | 2002-04-19 | 2008-05-27 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Beta-agonist compounds comprising nitric oxide donor groups and reactive oxygen species scavenger groups and their use in the treatment of respiratory disorders |
US9339459B2 (en) | 2003-04-24 | 2016-05-17 | Nektar Therapeutics | Particulate materials |
AU2003249623A1 (en) | 2002-05-09 | 2003-12-12 | Kurve Technology, Inc. | Particle dispersion chamber for nasal nebulizer |
US6889690B2 (en) | 2002-05-10 | 2005-05-10 | Oriel Therapeutics, Inc. | Dry powder inhalers, related blister devices, and associated methods of dispensing dry powder substances and fabricating blister packages |
US7118010B2 (en) * | 2002-05-10 | 2006-10-10 | Oriel Therapeutics, Inc. | Apparatus, systems and related methods for dispensing and /or evaluating dry powders |
US7677411B2 (en) | 2002-05-10 | 2010-03-16 | Oriel Therapeutics, Inc. | Apparatus, systems and related methods for processing, dispensing and/or evaluatingl dry powders |
US6985798B2 (en) * | 2002-05-10 | 2006-01-10 | Oriel Therapeutics, Inc. | Dry powder dose filling systems and related methods |
EP1534366B1 (en) | 2002-06-27 | 2014-01-08 | Oriel Therapeutics, Inc. | Dry powder dose filling systems and related methods |
CA2490409A1 (en) | 2002-06-28 | 2004-01-08 | Centocor, Inc. | Mammalian ch1 deleted mimetibodies, compositions, methods and uses |
AU2003278565A1 (en) * | 2002-10-25 | 2004-05-13 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Steroid compounds comprising superoxide dismutase mimic groups and nitric oxide donor groups, and their use in the preparation of medicaments |
MXPA05006321A (es) * | 2002-12-13 | 2005-08-26 | Otsuka Pharma Co Ltd | Dispositivo de inhalacion para administracion transpulmonar. |
GB0303870D0 (en) * | 2003-02-20 | 2003-03-26 | Norton Healthcare Ltd | Pre-metered dose magazine for breath-actuated dry powder inhaler |
PT1663235E (pt) | 2003-08-18 | 2013-10-29 | Parion Sciences Inc | Novos bloqueadores dos canais do sódio de pirazinoílguanidina protegida |
US20070131230A1 (en) * | 2003-09-05 | 2007-06-14 | Kurve Technology, Inc. | Nasal adapter for the base of the nose |
EP1673123A2 (en) * | 2003-09-05 | 2006-06-28 | Kurve Technology, Inc. | Integrated nebulizer and particle dispersing chamber for delivery of medicament |
CA2533887A1 (en) * | 2003-09-30 | 2005-04-14 | Acusphere, Inc. | Injectable, oral, or topical sustained release pharmaceutical formulations |
UA89481C2 (ru) | 2003-09-30 | 2010-02-10 | Центокор, Инк. | Эритропоэтиновые миметические шарнирно-сердцевинные миметитела человека, композиции, способы и применение |
US7338171B2 (en) * | 2003-10-27 | 2008-03-04 | Jen-Chuen Hsieh | Method and apparatus for visual drive control |
US7451761B2 (en) | 2003-10-27 | 2008-11-18 | Oriel Therapeutics, Inc. | Dry powder inhalers, related blister package indexing and opening mechanisms, and associated methods of dispensing dry powder substances |
US7377277B2 (en) | 2003-10-27 | 2008-05-27 | Oriel Therapeutics, Inc. | Blister packages with frames and associated methods of fabricating dry powder drug containment systems |
WO2005040163A1 (en) | 2003-10-28 | 2005-05-06 | Dr. Reddy's Laboratories Ltd | Heterocyclic compounds that block the effects of advanced glycation end products (age) |
EP1708738B1 (en) * | 2004-01-12 | 2016-05-04 | MannKind Corporation | A method of reducing serum proinsulin levels in type 2 diabetics |
GB0400804D0 (en) | 2004-01-14 | 2004-02-18 | Innoscience Technology Bv | Pharmaceutical compositions |
US7607435B2 (en) * | 2004-01-21 | 2009-10-27 | Battelle Memorial Institute | Gas or liquid flow sensor |
US7491194B1 (en) | 2004-02-03 | 2009-02-17 | David Oliwa | Remote control valve for urine collection bag |
US20080090753A1 (en) | 2004-03-12 | 2008-04-17 | Biodel, Inc. | Rapid Acting Injectable Insulin Compositions |
CA2563379A1 (en) | 2004-03-31 | 2005-10-20 | Centocor, Inc. | Human glp-1 mimetibodies, compositions, methods and uses |
CA2574958A1 (en) * | 2004-07-26 | 2006-02-09 | Cotherix, Inc. | Treatment of pulmonary hypertension by inhaled iloprost with a microparticle formulation |
BRPI0514263B8 (pt) | 2004-08-20 | 2021-05-25 | Mannkind Corp | método para a síntese de bis-3,6-[4-aminobutil]-2,5-dicetopiperazina n-protegida |
DK2314298T3 (en) | 2004-08-23 | 2015-06-15 | Mannkind Corp | Microparticles comprising diketopiperazinsalte for drug delivery |
US7393662B2 (en) | 2004-09-03 | 2008-07-01 | Centocor, Inc. | Human EPO mimetic hinge core mimetibodies, compositions, methods and uses |
GB0427858D0 (en) | 2004-12-20 | 2005-01-19 | Glaxo Group Ltd | Manifold for use in medicament dispenser |
GB0427856D0 (en) | 2004-12-20 | 2005-01-19 | Glaxo Group Ltd | Maniflod for use in medicament dispenser |
EP1674151B1 (de) | 2004-12-23 | 2008-04-16 | Kinematica Ag | Vorrichtung zum Dispergieren eines festen, flüssigen oder gasförmigen Stoffes in einer Flüssigkeit |
PE20061324A1 (es) | 2005-04-29 | 2007-01-15 | Centocor Inc | Anticuerpos anti-il-6, composiciones, metodos y usos |
JP2009501006A (ja) | 2005-06-30 | 2009-01-15 | セントカー・インコーポレーテツド | 抗il−23抗体、組成物、方法および用途 |
US7803404B2 (en) | 2005-09-14 | 2010-09-28 | Mannkind Corporation | Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces |
US20070086952A1 (en) * | 2005-09-29 | 2007-04-19 | Biodel, Inc. | Rapid Acting and Prolonged Acting Inhalable Insulin Preparations |
US7713929B2 (en) | 2006-04-12 | 2010-05-11 | Biodel Inc. | Rapid acting and long acting insulin combination formulations |
US8084420B2 (en) | 2005-09-29 | 2011-12-27 | Biodel Inc. | Rapid acting and long acting insulin combination formulations |
AR058289A1 (es) | 2005-12-12 | 2008-01-30 | Glaxo Group Ltd | Colector para ser usado en dispensador de medicamento |
EP1973523A2 (en) * | 2005-12-15 | 2008-10-01 | Acusphere, Inc. | Processes for making particle-based pharmaceutical formulations for pulmonary or nasal administration |
HUE034269T2 (en) | 2005-12-29 | 2018-02-28 | Janssen Biotech Inc | Human anti-IL-23 antibodies, preparations, methods and applications |
BRPI0707991B8 (pt) | 2006-02-22 | 2021-05-25 | Mannkind Corp | métodos de preparação de um medicamento em pó seco com uma propriedade farmacêutica melhorada, dito pó seco e uso de uma quantidade efetiva do pó seco |
CA2642229C (en) | 2006-02-24 | 2015-05-12 | Rigel Pharmaceuticals, Inc. | Compositions and methods for inhibition of the jak pathway |
US8037880B2 (en) * | 2006-04-07 | 2011-10-18 | The University Of Western Ontario | Dry powder inhaler |
DE102006016901A1 (de) * | 2006-04-11 | 2007-10-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Mundstück für einen Inhalator |
DE102006016904A1 (de) * | 2006-04-11 | 2007-10-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Inhalator |
US7718609B2 (en) | 2006-04-12 | 2010-05-18 | Biodel Inc. | Rapid acting and long acting insulin combination formulations |
PL2068889T3 (pl) | 2006-08-10 | 2020-06-29 | Roy C. Levitt | Anakinra do zastosowania do leczenia zespołu zarostowego zapalenia oskrzelików |
EP2106268B1 (en) | 2006-08-30 | 2018-12-12 | Kurve Technology, Inc. | Aerosol generating and delivery device |
UY30820A1 (es) | 2006-12-21 | 2008-07-03 | Centocor Inc | Uso de agonistas del receptor de glp-1 de accion prolongada para mejorar la sensibilidad a la insulina y los perfiles lipidicos |
US20080275030A1 (en) | 2007-01-19 | 2008-11-06 | Sveinbjorn Gizurarson | Methods and Compositions for the Delivery of a Therapeutic Agent |
US8496002B2 (en) | 2007-06-12 | 2013-07-30 | Civitas Therapeutics, Inc. | Powder inhaler devices |
US8785396B2 (en) | 2007-10-24 | 2014-07-22 | Mannkind Corporation | Method and composition for treating migraines |
CN101951913A (zh) | 2008-02-26 | 2011-01-19 | 帕里昂科学公司 | 聚芳族钠通道阻断剂 |
US8642831B2 (en) | 2008-02-29 | 2014-02-04 | Ferrosan Medical Devices A/S | Device for promotion of hemostasis and/or wound healing |
DK2254629T3 (en) * | 2008-03-27 | 2016-01-25 | Mannkind Corp | The dry powder inhalation |
AU2009257311B2 (en) * | 2008-06-13 | 2014-12-04 | Mannkind Corporation | A dry powder inhaler and system for drug delivery |
US9358352B2 (en) | 2008-06-13 | 2016-06-07 | Mannkind Corporation | Dry powder drug delivery system and methods |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
DK2300083T3 (da) | 2008-06-20 | 2013-07-22 | Mannkind Corp | Interaktivt apparat og fremgangsmåde til realtids-profilering af inhalationsforsøg |
US8517009B2 (en) | 2008-07-13 | 2013-08-27 | Map Pharmaceuticals, Inc. | Methods and apparatus for delivering aerosolized medication |
TWI494123B (zh) | 2008-08-11 | 2015-08-01 | Mannkind Corp | 超快起作用胰島素之用途 |
EP2326668B1 (en) | 2008-08-14 | 2018-01-17 | Teva Pharmaceuticals Australia Pty Ltd | Anti-il-12/il-23 antibodies |
WO2010051274A2 (en) | 2008-10-31 | 2010-05-06 | Centocor Ortho Biotech Inc. | Fibronectin type iii domain based scaffold compositions, methods and uses |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
US8324200B2 (en) | 2009-01-23 | 2012-12-04 | Rigel Pharmaceuticals, Inc. | Compositions and methods for inhibition of the JAK pathway |
RU2562700C2 (ru) | 2009-02-12 | 2015-09-10 | Янссен Байотек, Инк. | Композиции, способы получения и применение каркаса на основе домена фибронектина типа iii |
UA97784C2 (ru) | 2009-02-23 | 2012-03-12 | Джапан Тобакко Инк. | Ненагреваемое устройство для всасывания табачного аромата |
US9060927B2 (en) | 2009-03-03 | 2015-06-23 | Biodel Inc. | Insulin formulations for rapid uptake |
US8538707B2 (en) | 2009-03-11 | 2013-09-17 | Mannkind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
PL2411521T3 (pl) | 2009-03-25 | 2015-08-31 | Univ Texas | Kompozycje do stymulacji wrodzonej odporności immunologicznej na patogeny u ssaków |
FR2946537B1 (fr) | 2009-06-11 | 2012-08-03 | Valois Sas | Dispositif d'inhalation de poudre |
KR101875969B1 (ko) | 2009-06-12 | 2018-07-06 | 맨카인드 코포레이션 | 한정된 비표면적을 갖는 디케토피페라진 마이크로입자 |
WO2011056889A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
WO2011080761A1 (en) | 2009-12-30 | 2011-07-07 | Thirumalai Anadampillai Aparna | An improved dry powder inhaler |
AU2011210352A1 (en) | 2010-01-26 | 2012-08-09 | Radikal Therapeutics Inc. | Compositions and methods for prevention and treatment of pulmonary hypertension |
WO2011100403A1 (en) | 2010-02-10 | 2011-08-18 | Immunogen, Inc | Cd20 antibodies and uses thereof |
AU2011268110B2 (en) | 2010-06-19 | 2016-05-19 | Memorial Sloan-Kettering Cancer Center | Anti-GD2 antibodies |
ES2625858T3 (es) | 2011-04-01 | 2017-07-20 | Mannkind Corporation | Paquete de tipo blíster para cartuchos farmacéuticos |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
WO2012175735A1 (en) | 2011-06-23 | 2012-12-27 | Vib Vzw | A20 inhibitors for the treatment of respiratory viral infections |
DK2723176T3 (en) | 2011-06-27 | 2017-07-31 | Parion Sciences Inc | CHEMICAL AND METABOLIC STABLE DIPEPTIDE WITH POTENT SODIUM CHANNEL BLOCK ACTIVITY |
JP6018640B2 (ja) | 2011-10-24 | 2016-11-02 | マンカインド コーポレイション | 疼痛を緩和するのに有効な鎮痛組成物並びに当該組成物を含む乾燥粉末及び乾燥粉末薬剤輸送システム |
US11109849B2 (en) | 2012-03-06 | 2021-09-07 | Ferrosan Medical Devices A/S | Pressurized container containing haemostatic paste |
US8877967B2 (en) | 2012-03-23 | 2014-11-04 | Oxigene, Inc. | Compositions and methods for inhibition of cathepsins |
RU2636240C2 (ru) | 2012-06-12 | 2017-11-21 | Ферросан Медикал Дивайсиз А/С | Сухая гемостатическая композиция |
ES2624294T3 (es) | 2012-07-12 | 2017-07-13 | Mannkind Corporation | Sistemas de suministro de fármacos en polvo seco |
EP2911690A1 (en) | 2012-10-26 | 2015-09-02 | MannKind Corporation | Inhalable influenza vaccine compositions and methods |
TWI718086B (zh) | 2013-01-07 | 2021-02-11 | 英屬維爾京群島商遠東超級實驗室有限公司 | 通過干擾素的經皮和/或經粘膜給藥治療骨癌、皮膚癌、皮下癌、粘膜癌和/或粘膜下癌的方法和組合物 |
EP2970149B1 (en) | 2013-03-15 | 2019-08-21 | MannKind Corporation | Microcrystalline diketopiperazine compositions and methods |
EP2968545B1 (en) | 2013-03-15 | 2019-03-06 | Memorial Sloan Kettering Cancer Center | High affinity anti-gd2 antibodies |
US9724078B2 (en) | 2013-06-21 | 2017-08-08 | Ferrosan Medical Devices A/S | Vacuum expanded dry composition and syringe for retaining same |
CN114848614A (zh) | 2013-07-18 | 2022-08-05 | 曼金德公司 | 热稳定性干粉药物组合物和方法 |
CA2920488C (en) | 2013-08-05 | 2022-04-26 | Mannkind Corporation | Insufflation apparatus and methods |
US10111980B2 (en) | 2013-12-11 | 2018-10-30 | Ferrosan Medical Devices A/S | Dry composition comprising an extrusion enhancer |
WO2015148905A1 (en) | 2014-03-28 | 2015-10-01 | Mannkind Corporation | Use of ultrarapid acting insulin |
US10286065B2 (en) | 2014-09-19 | 2019-05-14 | Board Of Regents, The University Of Texas System | Compositions and methods for treating viral infections through stimulated innate immunity in combination with antiviral compounds |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
RU2715235C2 (ru) | 2014-10-13 | 2020-02-26 | Ферросан Медикал Дивайсиз А/С | Сухая композиция для использования при гемостазе и заживлении ран |
JP6747650B2 (ja) | 2014-12-24 | 2020-08-26 | フェロサン メディカル デバイシーズ エイ/エス | 第1の物質と第2の物質を保持し混合するためのシリンジ |
EP4190817A1 (en) | 2015-03-17 | 2023-06-07 | Memorial Sloan Kettering Cancer Center | Anti-muc16 antibodies and uses thereof |
CN107771093B (zh) | 2015-07-03 | 2021-06-15 | 弗罗桑医疗设备公司 | 用于混合两种组分和用于在存储条件下保持真空的注射器 |
CN109890841A (zh) | 2016-07-15 | 2019-06-14 | 波赛达治疗公司 | 嵌合抗原受体及使用方法 |
CA3027247A1 (en) | 2016-07-15 | 2018-01-18 | Poseida Therapeutics, Inc. | Chimeric antigen receptors (cars) specific for muc1 and methods for their use |
KR102515202B1 (ko) | 2016-11-09 | 2023-03-29 | 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 | 후천성 면역 조절을 위한 방법 및 조성물 |
EP3554503B1 (en) | 2016-12-16 | 2023-10-04 | The Board of Regents of The University of Texas System | Inhibitors of bromodomain-containing protein 4 (brd4) |
CA3051484A1 (en) | 2017-01-27 | 2018-08-02 | Memorial Sloan Kettering Cancer Center | Bispecific her2 and cd3 binding molecules |
CA3052095A1 (en) | 2017-01-30 | 2018-08-02 | Janssen Biotech, Inc. | Anti-tnf antibodies, compositions, and methods for the treatment of active psoriatic arthritis |
CA3052578A1 (en) | 2017-02-07 | 2018-08-16 | Janssen Biotech, Inc. | Anti-tnf antibodies, compositions, and methods for the treatment of active ankylosing spondylitis |
CN112218885A (zh) | 2017-12-20 | 2021-01-12 | 波赛达治疗公司 | Vcar组合物和使用方法 |
KR102016848B1 (ko) * | 2018-03-06 | 2019-08-30 | 주식회사 케이티앤지 | 흡연 물품용 카트리지 및 이의 에어로졸 흡입기 |
KR102019593B1 (ko) * | 2018-03-06 | 2019-09-06 | 주식회사 케이티앤지 | 에어로졸 흡입기 |
KR102019595B1 (ko) * | 2018-03-07 | 2019-09-06 | 주식회사 케이티앤지 | 담배 물질 흡입기 |
WO2019215173A1 (en) * | 2018-05-08 | 2019-11-14 | Societe Industrielle De Sonceboz Sa | Inhaler |
MX2020011866A (es) | 2018-05-09 | 2021-01-20 | Ferrosan Medical Devices As | Metodo para preparar una composicion hemostatica. |
MA52590A (fr) | 2018-05-11 | 2021-03-17 | Janssen Biotech Inc | Méthodes de traitement de la dépression à l'aide d'anticorps il-23 |
US11389433B2 (en) | 2018-06-18 | 2022-07-19 | Board Of Regents, The University Of Texas System | BRD4 inhibitor treatment of IgE-mediated diseases |
WO2020092845A1 (en) | 2018-11-01 | 2020-05-07 | Rigel Pharmaceuticals, Inc. | Method and composition embodiments for treating acute myeloid leukemia |
US11712529B2 (en) | 2018-12-13 | 2023-08-01 | ResMed Pty Ltd | Pneumatic block for respiratory pressure therapy device |
MA54750A (fr) | 2019-01-15 | 2021-11-24 | Janssen Biotech Inc | Compositions d'anticorps anti-tnf et procédés pour le traitement de l'arthrite idiopathique juvénile |
JP2022518250A (ja) | 2019-01-23 | 2022-03-14 | ヤンセン バイオテツク,インコーポレーテツド | 乾癬性関節炎の治療方法で使用するための抗tnf抗体組成物 |
EA202192505A1 (ru) | 2019-03-14 | 2022-03-29 | Янссен Байотек, Инк. | Способы получения композиций антитела к фно |
JP2022525179A (ja) | 2019-03-14 | 2022-05-11 | ヤンセン バイオテツク,インコーポレーテツド | 抗tnf抗体組成物を産生するための産生方法 |
MA55284A (fr) | 2019-03-14 | 2022-01-19 | Janssen Biotech Inc | Procédés de production de compositions d'anticorps anti-tnf |
WO2020234834A1 (en) | 2019-05-23 | 2020-11-26 | Janssen Biotech, Inc. | Method of treating inflammatory bowel disease with a combination therapy of antibodies to il-23 and tnf alpha |
US20200377518A1 (en) | 2019-05-29 | 2020-12-03 | Rigel Pharmaceuticals, Inc. | Method of preventing and treating thrombosis |
MA56026A (fr) | 2019-06-03 | 2022-04-06 | Janssen Biotech Inc | Anticorps anti-tnf, compositions et méthodes pour le traitement de la spondylarthrite ankylosante active |
MA56015A (fr) | 2019-06-03 | 2022-04-06 | Janssen Biotech Inc | Compositions d'anticorps anti-tnf et méthodes pour le traitement de l'arthrite psoriasique |
JP2022543843A (ja) | 2019-08-08 | 2022-10-14 | ライジェル ファーマシューティカルズ, インコーポレイテッド | サイトカイン放出症候群を治療するための化合物及び方法 |
WO2021030526A1 (en) | 2019-08-14 | 2021-02-18 | Rigel Pharmaceuticals, Inc. | Method of blocking or ameliorating cytokine release syndrome |
WO2021028752A1 (en) | 2019-08-15 | 2021-02-18 | Janssen Biotech, Inc. | Anti-tfn antibodies for treating type i diabetes |
MX2022012956A (es) | 2020-04-14 | 2023-03-27 | Poseida Therapeutics Inc | Composiciones y métodos para su uso en el tratamiento del cáncer. |
WO2021214588A1 (en) | 2020-04-21 | 2021-10-28 | Janssen Biotech, Inc. | Anti-tnf alpha agent for treating coronavirus infections |
WO2021214587A1 (en) | 2020-04-21 | 2021-10-28 | Janssen Biotech, Inc. | Anti-tnf alpha agent for treating viral infections |
US20230312684A1 (en) | 2020-07-31 | 2023-10-05 | Pinetree Therapeutics, Inc. | Neuropilin and angiotensin converting enzyme 2 fusion peptides for treating viral infections |
WO2023279115A1 (en) | 2021-07-02 | 2023-01-05 | Henry Ford Health System | Compositions comprising endosidin 2 for reducing sars-cov-2 infection |
US20230042465A1 (en) | 2021-07-09 | 2023-02-09 | Janssen Biotech, Inc. | Manufacturing Methods for Producing Anti-TNF Antibody Compositions |
WO2023281462A1 (en) | 2021-07-09 | 2023-01-12 | Janssen Biotech, Inc. | Manufacturing methods for producing anti-tnf antibody compositions |
TW202346291A (zh) | 2022-03-23 | 2023-12-01 | 美商雷傑製藥公司 | 作為irak抑制劑的嘧啶—2—基—吡唑化合物 |
Family Cites Families (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1262085A (en) * | 1965-03-19 | 1972-02-02 | Fisons Pharmaceuticals Ltd | Inhalation device |
GB1142015A (en) * | 1965-09-10 | 1969-02-05 | Unilever Ltd | Preservation of foodstuffs |
US3669113A (en) * | 1966-03-07 | 1972-06-13 | Fisons Ltd | Inhalation device |
GB1182779A (en) * | 1966-09-17 | 1970-03-04 | Fisons Pharmaceuticals Ltd | Inhalation Device |
US3507277A (en) * | 1966-09-17 | 1970-04-21 | Fisons Pharmaceuticals Ltd | Inhalation device |
GB1268051A (en) * | 1968-06-07 | 1972-03-22 | Fisons Pharmaceuticals Ltd | Inhalation device |
US3831606A (en) * | 1971-02-19 | 1974-08-27 | Alza Corp | Auto inhaler |
US3812853A (en) * | 1971-11-17 | 1974-05-28 | P Crain | Apparatus for applying medication or the like to human nasal passages |
US3971377A (en) * | 1974-06-10 | 1976-07-27 | Alza Corporation | Medicament dispensing process for inhalation therapy |
US4147166A (en) * | 1977-05-02 | 1979-04-03 | American Cyanamid Company | Oral inhalator powder dispenser |
ZA811942B (en) * | 1980-03-25 | 1983-02-23 | H Malem | Nebulising apparatus |
US4307734A (en) * | 1980-06-23 | 1981-12-29 | B & B Inventors & Marketers, Inc. | Snuff dispenser |
EP0069715B1 (en) * | 1981-07-08 | 1986-11-05 | Aktiebolaget Draco | Powder inhalator |
US4509515A (en) * | 1982-02-23 | 1985-04-09 | Fisons Plc | Inhalation device |
FI79651C (fi) * | 1982-10-08 | 1990-02-12 | Glaxo Group Ltd | Doseringsanordning foer medicin. |
US4534343A (en) * | 1984-01-27 | 1985-08-13 | Trutek Research, Inc. | Metered dose inhaler |
SE448277B (sv) * | 1985-04-12 | 1987-02-09 | Draco Ab | Indikeringsanordning vid en doseringsanordning for lekemedel |
AT384552B (de) * | 1985-08-01 | 1987-12-10 | Hurka Wilhelm | Inhalationsgeraet zur dosierung und verteilung von festkoerpern in die atemluft |
US4739754A (en) * | 1986-05-06 | 1988-04-26 | Shaner William T | Suction resistant inhalator |
JPH05501505A (ja) * | 1989-04-28 | 1993-03-25 | ライカー ラボラトリーズ,インコーポレイティド | 乾燥粉末吸入装置 |
US5176132A (en) * | 1989-05-31 | 1993-01-05 | Fisons Plc | Medicament inhalation device and formulation |
IT1237118B (it) * | 1989-10-27 | 1993-05-18 | Miat Spa | Inalatore multidose per farmaci in polvere. |
US5113855A (en) * | 1990-02-14 | 1992-05-19 | Newhouse Michael T | Powder inhaler |
GB9021433D0 (en) * | 1990-10-02 | 1990-11-14 | Atomic Energy Authority Uk | Power inhaler |
US5327883A (en) * | 1991-05-20 | 1994-07-12 | Dura Pharmaceuticals, Inc. | Apparatus for aerosolizing powdered medicine and process and using |
US5161524A (en) * | 1991-08-02 | 1992-11-10 | Glaxo Inc. | Dosage inhalator with air flow velocity regulating means |
-
1993
- 1993-10-12 BR BR9307270A patent/BR9307270A/pt not_active IP Right Cessation
- 1993-10-12 RO RO95-00764A patent/RO113214B1/ro unknown
- 1993-10-12 PL PL93308367A patent/PL172758B1/pl unknown
- 1993-10-12 UA UA95048332A patent/UA27938C2/ru unknown
- 1993-10-12 WO PCT/US1993/009751 patent/WO1994008552A2/en active IP Right Grant
- 1993-10-12 CZ CZ95977A patent/CZ282964B6/cs not_active IP Right Cessation
- 1993-10-12 AU AU53289/94A patent/AU679700B2/en not_active Ceased
- 1993-10-12 ES ES93923378T patent/ES2127837T3/es not_active Expired - Lifetime
- 1993-10-12 RU RU95114532A patent/RU2141849C1/ru active
- 1993-10-12 NZ NZ257056A patent/NZ257056A/en unknown
- 1993-10-12 SK SK503-95A patent/SK279327B6/sk unknown
- 1993-10-12 EP EP93923378A patent/EP0665759B1/en not_active Expired - Lifetime
- 1993-10-12 DE DE69322789T patent/DE69322789T2/de not_active Expired - Fee Related
- 1993-10-12 SK SK516-95A patent/SK51695A3/sk unknown
- 1993-10-12 HU HU9501102A patent/HU217917B/hu not_active IP Right Cessation
- 1993-10-12 KR KR1019950701477A patent/KR0177265B1/ko not_active IP Right Cessation
- 1993-10-12 JP JP6510219A patent/JP2912453B2/ja not_active Expired - Lifetime
- 1993-10-12 AT AT93923378T patent/ATE174804T1/de not_active IP Right Cessation
- 1993-10-12 CA CA002147260A patent/CA2147260C/en not_active Expired - Fee Related
- 1993-10-12 DK DK93923378T patent/DK0665759T3/da active
- 1993-10-14 US US08/137,282 patent/US5577497A/en not_active Expired - Fee Related
-
1994
- 1994-01-12 TW TW083100186A patent/TW235245B/zh active
-
1995
- 1995-04-14 BG BG99579A patent/BG61554B1/bg unknown
- 1995-04-18 FI FI951838A patent/FI951838A0/fi unknown
- 1995-04-19 NO NO19951478A patent/NO311870B1/no not_active IP Right Cessation
-
1998
- 1998-12-22 HK HK98114661A patent/HK1013262A1/xx not_active IP Right Cessation
-
1999
- 1999-03-19 GR GR990400817T patent/GR3029732T3/el unknown
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