MA55284A - Procédés de production de compositions d'anticorps anti-tnf - Google Patents

Procédés de production de compositions d'anticorps anti-tnf

Info

Publication number
MA55284A
MA55284A MA055284A MA55284A MA55284A MA 55284 A MA55284 A MA 55284A MA 055284 A MA055284 A MA 055284A MA 55284 A MA55284 A MA 55284A MA 55284 A MA55284 A MA 55284A
Authority
MA
Morocco
Prior art keywords
methods
antibody compositions
tnf antibody
producing anti
producing
Prior art date
Application number
MA055284A
Other languages
English (en)
Inventor
Kristopher Barnthouse
Subinay Ganguly
Maarten Groeneveld
Manual A Lopez Jr
Michael Nedved
Kevin D Smith
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of MA55284A publication Critical patent/MA55284A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41—Glycosylation, sialylation, or fucosylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567—Framework region [FR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
MA055284A 2019-03-14 2020-02-26 Procédés de production de compositions d'anticorps anti-tnf MA55284A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201962818305P 2019-03-14 2019-03-14

Publications (1)

Publication Number Publication Date
MA55284A true MA55284A (fr) 2022-01-19

Family

ID=69784491

Family Applications (1)

Application Number Title Priority Date Filing Date
MA055284A MA55284A (fr) 2019-03-14 2020-02-26 Procédés de production de compositions d'anticorps anti-tnf

Country Status (12)

Country Link
US (1) US20220153829A1 (fr)
EP (1) EP3938392A1 (fr)
JP (1) JP2022524860A (fr)
KR (1) KR20210141998A (fr)
CN (1) CN113840837A (fr)
AR (1) AR118353A1 (fr)
CA (1) CA3133388A1 (fr)
EA (1) EA202192508A1 (fr)
IL (1) IL286307A (fr)
MA (1) MA55284A (fr)
TW (1) TW202100552A (fr)
WO (1) WO2020183271A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023281462A1 (fr) * 2021-07-09 2023-01-12 Janssen Biotech, Inc. Procédés de fabrication pour produire des compositions d'anticorps anti-tnf
CN117957251A (zh) * 2021-07-09 2024-04-30 詹森生物科技公司 用于制备抗tnf抗体组合物的制造方法

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EP3323826A1 (fr) * 2016-11-21 2018-05-23 Danmarks Tekniske Universitet Peptides de signal de sécrétion natifs de cellules d'ovaire de hamster chinois pour la production de polypeptides recombinés

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EA202192508A1 (ru) 2022-03-29
EP3938392A1 (fr) 2022-01-19
CN113840837A (zh) 2021-12-24
JP2022524860A (ja) 2022-05-10
IL286307A (en) 2021-10-31
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AR118353A1 (es) 2021-09-29
US20220153829A1 (en) 2022-05-19

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