ATE140731T1 - Plasmidvektor mit pectatlyase-signalsequenz - Google Patents
Plasmidvektor mit pectatlyase-signalsequenzInfo
- Publication number
- ATE140731T1 ATE140731T1 AT89901763T AT89901763T ATE140731T1 AT E140731 T1 ATE140731 T1 AT E140731T1 AT 89901763 T AT89901763 T AT 89901763T AT 89901763 T AT89901763 T AT 89901763T AT E140731 T1 ATE140731 T1 AT E140731T1
- Authority
- AT
- Austria
- Prior art keywords
- pectatlyase
- signal sequence
- plasmid vector
- vector
- thaumatin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
- C07K14/43—Sweetening agents, e.g. thaumatin, monellin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3046—Stomach, Intestines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/46—Hybrid immunoglobulins
- C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
- C07K16/462—Igs containing a variable region (Fv) from one specie and a constant region (Fc) from another
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/034—Fusion polypeptide containing a localisation/targetting motif containing a motif for targeting to the periplasmic space of Gram negative bacteria as a soluble protein, i.e. signal sequence should be cleaved
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14203988A | 1988-01-11 | 1988-01-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE140731T1 true ATE140731T1 (de) | 1996-08-15 |
Family
ID=22498331
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89901763T ATE140731T1 (de) | 1988-01-11 | 1989-01-09 | Plasmidvektor mit pectatlyase-signalsequenz |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0396612B1 (de) |
| JP (1) | JP2980626B2 (de) |
| AT (1) | ATE140731T1 (de) |
| CA (1) | CA1338807C (de) |
| DE (1) | DE68926882T2 (de) |
| WO (1) | WO1989006283A1 (de) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5618920A (en) * | 1985-11-01 | 1997-04-08 | Xoma Corporation | Modular assembly of antibody genes, antibodies prepared thereby and use |
| US5576195A (en) * | 1985-11-01 | 1996-11-19 | Xoma Corporation | Vectors with pectate lyase signal sequence |
| CA1341235C (en) * | 1987-07-24 | 2001-05-22 | Randy R. Robinson | Modular assembly of antibody genes, antibodies prepared thereby and use |
| ES2080689B1 (es) * | 1994-04-21 | 1996-09-01 | Urquima Sa | Procedimiento de obtencion de un edulcorante natural proteico. |
| GB9610967D0 (en) | 1996-05-24 | 1996-07-31 | Cambridge Antibody Tech | Specific binding members,materials and methods |
| EP1048732A1 (de) * | 1999-04-26 | 2000-11-02 | F. Hoffmann-La Roche Ag | Verfahren zur Herstellung von natürlich gefalteten und sekretierten Proteinen |
| EP1077263A1 (de) | 1999-07-29 | 2001-02-21 | F.Hoffmann-La Roche Ag | Verfahren zur Herstellung von natürlich gefalteten und sekretierten Proteinen durch Co-Sekretion von Chaperonen |
| CA2400622A1 (en) | 2000-02-24 | 2001-08-30 | Eidgenossische Technische Hochschule Zurich | Antibody specific for the ed-b domain of fibronectin, conjugates comprising said antibody, and their use for the detection and treatment of angiogenesis |
| UA81743C2 (uk) | 2000-08-07 | 2008-02-11 | Центокор, Инк. | МОНОКЛОНАЛЬНЕ АНТИТІЛО ЛЮДИНИ, ЩО СПЕЦИФІЧНО ЗВ'ЯЗУЄТЬСЯ З ФАКТОРОМ НЕКРОЗУ ПУХЛИН АЛЬФА (ФНПα), ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ, ЩО ЙОГО МІСТИТЬ, ТА СПОСІБ ЛІКУВАННЯ РЕВМАТОЇДНОГО АРТРИТУ |
| US7288390B2 (en) | 2000-08-07 | 2007-10-30 | Centocor, Inc. | Anti-dual integrin antibodies, compositions, methods and uses |
| US6902734B2 (en) | 2000-08-07 | 2005-06-07 | Centocor, Inc. | Anti-IL-12 antibodies and compositions thereof |
| US9708410B2 (en) | 2003-05-30 | 2017-07-18 | Janssen Biotech, Inc. | Anti-tissue factor antibodies and compositions |
| CN101090969B (zh) * | 2004-12-07 | 2013-01-16 | 隆萨股份公司 | 鼠李糖启动子表达系统及用途 |
| DE102006044841A1 (de) | 2006-09-22 | 2008-04-03 | Wacker Chemie Ag | Signalpeptid zur Produktion von rekombinanten Proteinen |
| CN102316894A (zh) | 2008-06-20 | 2012-01-11 | 惠氏有限责任公司 | 来自β-溶血性链球菌菌株的ORF1358的组合物和使用方法 |
| CA2733642A1 (en) | 2008-08-14 | 2010-02-18 | Cephalon Australia Pty Ltd | Anti-il-12/il-23 antibodies |
| CN102459591B (zh) | 2009-05-20 | 2015-05-13 | 诺维莫尼公司 | 合成性的多肽文库以及用于建立具有天然多样性的多肽变体的方法 |
| PT3712174T (pt) | 2013-12-24 | 2022-05-27 | Janssen Pharmaceutica Nv | Anticorpos e fragmentos anti-vista |
| DK3313882T3 (da) | 2015-06-24 | 2020-05-11 | Janssen Pharmaceutica Nv | Anti-VISTA antistoffer og fragmenter |
| MX2018009800A (es) | 2016-02-12 | 2018-11-09 | Janssen Pharmaceutica Nv | Anticuerpos y fragmentos anti-vista, usos de los mismos y procedimientos de identificacion de los mismos. |
| AU2017241776A1 (en) | 2016-03-29 | 2018-10-11 | Janssen Biotech, Inc. | Treating psoriasis with increased interval dosing of anti-IL12 and/or -23 antibody |
| WO2017175058A1 (en) | 2016-04-07 | 2017-10-12 | Janssen Pharmaceutica Nv | Anti-vista antibodies and fragments, uses thereof, and methods of identifying same |
| WO2018064436A1 (en) | 2016-09-30 | 2018-04-05 | Janssen Biotech, Inc. | Safe and effective method of treating psoriasis with anti-il23 specific antibody |
| JP2020502261A (ja) | 2016-11-16 | 2020-01-23 | ヤンセン バイオテツク，インコーポレーテツド | 抗ｉｌ２３特異的抗体で乾癬を治療する方法 |
| KR20190113858A (ko) | 2017-01-30 | 2019-10-08 | 얀센 바이오테크 인코포레이티드 | 활성 건선성 관절염의 치료를 위한 항-tnf 항체, 조성물, 및 방법 |
| WO2018147915A1 (en) | 2017-02-07 | 2018-08-16 | Janssen Biotech, Inc. | Anti-tnf antibodies, compositions, and methods for the treatment of active ankylosing spondylitis |
| TW201922780A (zh) | 2017-09-25 | 2019-06-16 | 美商健生生物科技公司 | 以抗ｉｌ１２／ｉｌ２３抗體治療狼瘡之安全且有效之方法 |
| WO2019150309A1 (en) | 2018-02-02 | 2019-08-08 | Hammack Scott | Modulators of gpr68 and uses thereof for treating and preventing diseases |
| US20190269757A1 (en) | 2018-03-05 | 2019-09-05 | Janssen Biotech, Inc. | Methods of Treating Crohn's Disease with Anti-IL23 Specific Antibody |
| US20200025776A1 (en) | 2018-07-18 | 2020-01-23 | Janssen Biotech, Inc. | Sustained Response Predictors After Treatment With Anti-IL23 Specific Antibody |
| AU2019346134B2 (en) | 2018-09-24 | 2023-01-12 | Janssen Biotech, Inc. | Safe and effective method of treating ulcerative colitis with anti-il12/il23 antibody |
| MX2021005905A (es) | 2018-11-20 | 2021-06-23 | Janssen Biotech Inc | Metodo seguro y eficaz para tratar la psoriasis con el anticuerpo especifico anti-il-23. |
| WO2020128864A1 (en) | 2018-12-18 | 2020-06-25 | Janssen Biotech, Inc. | Safe and effective method of treating lupus with anti-il12/il23 antibody |
| MX2021008537A (es) | 2019-01-15 | 2021-11-12 | Janssen Biotech Inc | Composiciones de anticuerpos anti-tnf y métodos para el tratamiento de la artritis idiopática juvenil. |
| CA3127748A1 (en) | 2019-01-23 | 2020-07-30 | Janssen Biotech, Inc. | Anti-tnf antibody compositions for use in methods for the treatment of psoriatic arthritis |
| EA202192505A1 (ru) | 2019-03-14 | 2022-03-29 | Янссен Байотек, Инк. | Способы получения композиций антитела к фно |
| KR20210142002A (ko) | 2019-03-14 | 2021-11-23 | 얀센 바이오테크 인코포레이티드 | 항-tnf 항체 조성물을 생성하기 위한 제조 방법 |
| JP2022524860A (ja) | 2019-03-14 | 2022-05-10 | ヤンセン バイオテツク，インコーポレーテツド | 抗ｔｎｆ抗体組成物を産生するための方法 |
| KR20210141990A (ko) | 2019-03-14 | 2021-11-23 | 얀센 바이오테크 인코포레이티드 | 항-il12/il23 항체 조성물을 생성하기 위한 제조 방법 |
| AU2020243588A1 (en) | 2019-03-18 | 2021-10-07 | Janssen Biotech, Inc. | Method of treating psoriasis in pediatric subjects with anti-IL12/IL23 antibody |
| AU2020279987A1 (en) | 2019-05-23 | 2021-11-18 | Janssen Biotech, Inc. | Method of treating inflammatory bowel disease with a combination therapy of antibodies to IL-23 and TNF alpha |
| AU2020288404A1 (en) | 2019-06-03 | 2022-02-03 | Janssen Biotech, Inc. | Anti-TNF antibodies, compositions, and methods for the treatment of active Ankylosing Spondylitis |
| CN113939531A (zh) | 2019-06-03 | 2022-01-14 | 詹森生物科技公司 | 用于治疗银屑病关节炎的抗tnf抗体组合物和方法 |
| WO2021028752A1 (en) | 2019-08-15 | 2021-02-18 | Janssen Biotech, Inc. | Anti-tfn antibodies for treating type i diabetes |
| KR20230156387A (ko) | 2021-03-12 | 2023-11-14 | 얀센 바이오테크 인코포레이티드 | 항-il23 특이적 항체에 의해 건선성 관절염을 치료하는 안전하고 효과적인 방법 |
| BR112023018400A2 (pt) | 2021-03-12 | 2023-12-12 | Janssen Biotech Inc | Método para tratamento de pacientes de artrite psoriática com resposta inadequada à terapia de tnf com anticorpo específico anti-il23 |
| AU2022306973A1 (en) | 2021-07-09 | 2024-02-22 | Janssen Biotech, Inc. | Manufacturing methods for producing anti-il12/il23 antibody compositions |
| EP4367136A1 (de) | 2021-07-09 | 2024-05-15 | Janssen Biotech, Inc. | Herstellungsverfahren zur herstellung von anti-tnf-antikörperzusammensetzungen |
| EP4367137A1 (de) | 2021-07-09 | 2024-05-15 | Janssen Biotech, Inc. | Herstellungsverfahren zur herstellung von anti-tnf-antikörperzusammensetzungen |
| WO2023073615A1 (en) | 2021-10-29 | 2023-05-04 | Janssen Biotech, Inc. | Methods of treating crohn's disease with anti-il23 specific antibody |
| US20230151087A1 (en) | 2021-11-15 | 2023-05-18 | Janssen Biotech, Inc. | Methods of Treating Crohn's Disease with Anti-IL23 Specific Antibody |
| WO2023095000A1 (en) | 2021-11-23 | 2023-06-01 | Janssen Biotech, Inc. | Method of treating ulcerative colitis with anti-il23 specific antibody |
| US20230312703A1 (en) | 2022-03-30 | 2023-10-05 | Janssen Biotech, Inc. | Method of Treating Psoriasis with IL-23 Specific Antibody |
| US20230374122A1 (en) | 2022-05-18 | 2023-11-23 | Janssen Biotech, Inc. | Method for Evaluating and Treating Psoriatic Arthritis with IL23 Antibody |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6030687A (ja) * | 1983-08-01 | 1985-02-16 | Wakunaga Seiyaku Kk | Ｄνａ遺伝子，その製造法およびそれを含むプラスミド |
| JPS6368087A (ja) * | 1986-09-09 | 1988-03-26 | Oji Paper Co Ltd | 蛋白質の発現と分泌に関与する領域を含むｄｎａ |
| GB8702475D0 (en) * | 1987-02-04 | 1987-03-11 | Ciba Geigy Ag | Expression system |
| CA1341235C (en) * | 1987-07-24 | 2001-05-22 | Randy R. Robinson | Modular assembly of antibody genes, antibodies prepared thereby and use |
-
1989
- 1989-01-09 EP EP89901763A patent/EP0396612B1/de not_active Expired - Lifetime
- 1989-01-09 AT AT89901763T patent/ATE140731T1/de not_active IP Right Cessation
- 1989-01-09 DE DE68926882T patent/DE68926882T2/de not_active Expired - Lifetime
- 1989-01-09 WO PCT/US1989/000077 patent/WO1989006283A1/en active IP Right Grant
- 1989-01-09 JP JP1501661A patent/JP2980626B2/ja not_active Expired - Lifetime
- 1989-01-10 CA CA000587885A patent/CA1338807C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE68926882T2 (de) | 1997-02-13 |
| EP0396612B1 (de) | 1996-07-24 |
| DE68926882D1 (de) | 1996-08-29 |
| JPH04503151A (ja) | 1992-06-11 |
| CA1338807C (en) | 1996-12-24 |
| EP0396612A1 (de) | 1990-11-14 |
| EP0396612A4 (en) | 1991-10-02 |
| JP2980626B2 (ja) | 1999-11-22 |
| WO1989006283A1 (en) | 1989-07-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE140731T1 (de) | Plasmidvektor mit pectatlyase-signalsequenz | |
| PT88115A (pt) | Dna constructs containing a kluyveromyces alpha-factor leader sequence for directing secretion of heterologous polypetides | |
| PT100637A (pt) | Receptor ctla4 e metodos para a sua utilizacao | |
| IL89011A0 (en) | Receptor protein,dna sequence coding therefor and process for the preparation thereof | |
| DK666888D0 (da) | Human vaevsfaktor-relaterende dna-segmenter, polypeptider og antistoffer | |
| ATE46536T1 (de) | Verfahren zur herstellung von reifen proteinen in wirtzellen von wirbeltieren. | |
| AU573523B2 (en) | Functional human urokinase proteins | |
| IE820984L (en) | Plasmids coding for b. thuringiensis crystal protein | |
| DK1246917T3 (da) | Humane Stra6-polypeptider | |
| IE832452L (en) | Lymphocyte growth factor | |
| ES8505406A1 (es) | Procedimiento de obtener y aislar hibridomas secretores de anticuerpos, procedimiento de obtener anticuerpos y metodo de obtener polipeptidos | |
| DK1520860T3 (da) | Rekombinant protein PilC, fremgangsmåde til dets fremstilling og anvendelse deraf | |
| DE3688974D1 (de) | Expressionssysteme zur überproduktion gewünschter proteine. | |
| FI934079A (fi) | Menetelmä fuusioproteiinin valmistamiseksi |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EELA | Cancelled due to lapse of time |