RU2753248C2 - Генная терапия для рецессивного дистрофического буллезного эпидермолиза с использованием генетически корректированных аутологичных кератиноцитов - Google Patents
Генная терапия для рецессивного дистрофического буллезного эпидермолиза с использованием генетически корректированных аутологичных кератиноцитов Download PDFInfo
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| PCT/US2017/012061 WO2017120147A1 (en) | 2016-01-04 | 2017-01-03 | Gene therapy for recessive dystrophic epidermolysis bullosa using genetically corrected autologous keratinocytes |
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| EP3842520A1 (en) * | 2016-01-04 | 2021-06-30 | The Board of Trustees of the Leland Stanford Junior University | Gene therapy for recessive dystrophic epidermolysis bullosa using genetically corrected autologous keratinocytes |
| IT201700094210A1 (it) * | 2017-08-17 | 2019-02-17 | Holostem Terapie Avanzate S R L | Metodo per produrre lembi cellulari |
| IT201700104587A1 (it) * | 2017-09-19 | 2019-03-19 | Holostem Terapie Avanzate S R L | Usi terapeutici di lembi di cellule geneticamente modificate |
| SG11202005934WA (en) * | 2017-12-29 | 2020-07-29 | Genemedicine Co Ltd | Cell sheet for gene delivery |
| RU2730661C2 (ru) * | 2018-12-27 | 2020-08-24 | Селл энд Джин Терапи Лтд | Генотерапевтический ДНК-вектор на основе генотерапевтического ДНК-вектора VTvaf17, несущий целевой ген, выбранный из группы генов COL1A1, COL1A2, P4HA1, P4HA2, COL7A1, CLCA2, ELN, PLOD1 для повышения уровня экспрессии этих целевых генов, способ его получения и применения, штамм Escherichia coli SCS110-AF/VTvaf17-COL1A1, или Escherichia coli SCS110-AF/VTvaf17-COL1A2, или Escherichia coli SCS110-AF/VTvaf17-P4HA1, или Escherichia coli SCS110-AF/VTvaf17-P4HA2, или Escherichia coli SCS110-AF/VTvaf17-COL7A1, или Escherichia coli SCS110-AF/VTvaf17-CLCA2, или Escherichia coli SCS110-AF/VTvaf17-ELN, или Escherichia coli SCS110-AF/VTvaf17- PLOD1, несущий генотерапевтический ДНК-вектор, способ его получения, способ производства в промышленных масштабах генотерапевтического ДНК-вектора |
| KR20210116531A (ko) | 2019-01-18 | 2021-09-27 | 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸 | 영양 장애형 표피 수포증 치료약 |
| CN116529361B (zh) * | 2019-10-18 | 2024-01-26 | 北赛泓升(北京)生物科技有限公司 | 使用多顺反子sox2、klf4和任选的c-myc产生诱导多能干细胞 |
| KR20230043906A (ko) | 2020-07-22 | 2023-03-31 | 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸 | 영양 장애형 표피 수포증의 치료약 |
| MX2024004434A (es) | 2021-10-12 | 2024-07-09 | Phoenix Tissue Repair Inc | Terapia de reemplazo de proteínas con colágeno 7. |
| JP2025094280A (ja) | 2022-01-21 | 2025-06-25 | 国立大学法人大阪大学 | 細胞シート |
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| US5830725A (en) * | 1995-04-28 | 1998-11-03 | The Board Of Trustees For The Leland Stanford Junior University | Rapid, stable high-titre production of recombing retrovirus |
| US20020090725A1 (en) | 2000-11-17 | 2002-07-11 | Simpson David G. | Electroprocessed collagen |
| MXPA02000152A (es) * | 1999-07-02 | 2002-07-30 | Human Genome Sciences Inc | Factor 2 de crecimiento de queratinocitos. |
| FR2857671B1 (fr) * | 2003-07-18 | 2007-10-05 | Centre Nat Rech Scient | Nouveau procede de culture de keratinocytes et ses applications |
| CN1916166B (zh) * | 2006-09-08 | 2010-08-11 | 北京赛尔泰和生物医药科技有限公司 | 自体角膜上皮的制备方法 |
| US8865199B2 (en) * | 2008-11-17 | 2014-10-21 | Ingeneron, Inc. | Biomatrix composition and methods of biomatrix seeding |
| GB201202561D0 (en) * | 2012-02-15 | 2012-03-28 | Univ Dundee | Treatment of skin disorders |
| JP6334550B2 (ja) * | 2012-11-06 | 2018-05-30 | インベッド バイオサイエンシズ，インコーポレイテッド | 創傷治癒の方法と組成物 |
| US8697359B1 (en) | 2012-12-12 | 2014-04-15 | The Broad Institute, Inc. | CRISPR-Cas systems and methods for altering expression of gene products |
| CN105087565A (zh) * | 2015-08-21 | 2015-11-25 | 内蒙古自治区人民医院 | 一种营养不良型大疱性表皮松解症核苷酸及其应用 |
| EP3842520A1 (en) * | 2016-01-04 | 2021-06-30 | The Board of Trustees of the Leland Stanford Junior University | Gene therapy for recessive dystrophic epidermolysis bullosa using genetically corrected autologous keratinocytes |
| US20190192636A1 (en) * | 2016-03-18 | 2019-06-27 | Intrexon Corporation | Compositions and methods for treatment of type viii collagen deficiencies |
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