CN114699558B - 使用经遗传矫正的自体角质形成细胞进行的隐性营养不良型大疱性表皮松解症的基因疗法 - Google Patents

使用经遗传矫正的自体角质形成细胞进行的隐性营养不良型大疱性表皮松解症的基因疗法 Download PDF

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CN114699558B
CN114699558B CN202210368934.5A CN202210368934A CN114699558B CN 114699558 B CN114699558 B CN 114699558B CN 202210368934 A CN202210368934 A CN 202210368934A CN 114699558 B CN114699558 B CN 114699558B
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cells
use according
corneal epithelial
test
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CN114699558A (zh
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祖拉布·希普拉什维利
尼贡·T·纽伦
M·皮特·马林科维奇
吉恩·唐
阿尔弗雷德·T·莱恩
保罗·A·卡瓦里
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US Department of Veterans Affairs
Leland Stanford Junior University
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Leland Stanford Junior University
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CN202210368934.5A 2016-01-04 2017-01-03 使用经遗传矫正的自体角质形成细胞进行的隐性营养不良型大疱性表皮松解症的基因疗法 Expired - Fee Related CN114699558B (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201662274700P 2016-01-04 2016-01-04
US62/274,700 2016-01-04
US201662414533P 2016-10-28 2016-10-28
US62/414,533 2016-10-28
CN201780005233.2A CN108473952B (zh) 2016-01-04 2017-01-03 使用经遗传矫正的自体角质形成细胞进行的隐性营养不良型大疱性表皮松解症的基因疗法
PCT/US2017/012061 WO2017120147A1 (en) 2016-01-04 2017-01-03 Gene therapy for recessive dystrophic epidermolysis bullosa using genetically corrected autologous keratinocytes

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CN114699558B true CN114699558B (zh) 2023-07-28

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CN201780005233.2A Expired - Fee Related CN108473952B (zh) 2016-01-04 2017-01-03 使用经遗传矫正的自体角质形成细胞进行的隐性营养不良型大疱性表皮松解症的基因疗法

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EP3842520A1 (en) * 2016-01-04 2021-06-30 The Board of Trustees of the Leland Stanford Junior University Gene therapy for recessive dystrophic epidermolysis bullosa using genetically corrected autologous keratinocytes
IT201700094210A1 (it) * 2017-08-17 2019-02-17 Holostem Terapie Avanzate S R L Metodo per produrre lembi cellulari
IT201700104587A1 (it) * 2017-09-19 2019-03-19 Holostem Terapie Avanzate S R L Usi terapeutici di lembi di cellule geneticamente modificate
SG11202005934WA (en) * 2017-12-29 2020-07-29 Genemedicine Co Ltd Cell sheet for gene delivery
RU2730661C2 (ru) * 2018-12-27 2020-08-24 Селл энд Джин Терапи Лтд Генотерапевтический ДНК-вектор на основе генотерапевтического ДНК-вектора VTvaf17, несущий целевой ген, выбранный из группы генов COL1A1, COL1A2, P4HA1, P4HA2, COL7A1, CLCA2, ELN, PLOD1 для повышения уровня экспрессии этих целевых генов, способ его получения и применения, штамм Escherichia coli SCS110-AF/VTvaf17-COL1A1, или Escherichia coli SCS110-AF/VTvaf17-COL1A2, или Escherichia coli SCS110-AF/VTvaf17-P4HA1, или Escherichia coli SCS110-AF/VTvaf17-P4HA2, или Escherichia coli SCS110-AF/VTvaf17-COL7A1, или Escherichia coli SCS110-AF/VTvaf17-CLCA2, или Escherichia coli SCS110-AF/VTvaf17-ELN, или Escherichia coli SCS110-AF/VTvaf17- PLOD1, несущий генотерапевтический ДНК-вектор, способ его получения, способ производства в промышленных масштабах генотерапевтического ДНК-вектора
KR20210116531A (ko) 2019-01-18 2021-09-27 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸 영양 장애형 표피 수포증 치료약
CN116529361B (zh) * 2019-10-18 2024-01-26 北赛泓升(北京)生物科技有限公司 使用多顺反子sox2、klf4和任选的c-myc产生诱导多能干细胞
KR20230043906A (ko) 2020-07-22 2023-03-31 고꾸리쯔 다이가꾸 호우징 오사까 다이가꾸 영양 장애형 표피 수포증의 치료약
MX2024004434A (es) 2021-10-12 2024-07-09 Phoenix Tissue Repair Inc Terapia de reemplazo de proteínas con colágeno 7.
JP2025094280A (ja) 2022-01-21 2025-06-25 国立大学法人大阪大学 細胞シート

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EP3842520A1 (en) * 2016-01-04 2021-06-30 The Board of Trustees of the Leland Stanford Junior University Gene therapy for recessive dystrophic epidermolysis bullosa using genetically corrected autologous keratinocytes
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IL260038B (en) 2022-07-01
RU2021121824A (ru) 2021-08-18
CN108473952B (zh) 2022-04-08
US20250075178A1 (en) 2025-03-06
PT3400287T (pt) 2021-03-17
EP3842520A1 (en) 2021-06-30
CN114699558A (zh) 2022-07-05
WO2017120147A1 (en) 2017-07-13
JP2019506925A (ja) 2019-03-14
US20190382724A1 (en) 2019-12-19
IL293465A (en) 2022-08-01
US20240067926A1 (en) 2024-02-29
JP7555380B2 (ja) 2024-09-24
RU2018127524A3 (enExample) 2020-01-27
RU2018127524A (ru) 2020-01-27
US12173314B2 (en) 2024-12-24
IL293465B1 (en) 2023-04-01
DK3400287T3 (da) 2021-03-01
JP2023002634A (ja) 2023-01-10
AU2020239779A1 (en) 2020-10-22
MX2018007986A (es) 2018-11-09
ZA201803962B (en) 2023-01-25
RU2753248C2 (ru) 2021-08-12
ES2861453T3 (es) 2021-10-06
CN108473952A (zh) 2018-08-31
JP2024167419A (ja) 2024-12-03
AU2017205925A1 (en) 2018-07-12
US12110504B2 (en) 2024-10-08
CA3008676A1 (en) 2017-07-13
IL293465B2 (en) 2023-08-01
US20250257319A1 (en) 2025-08-14
IL260038A (enExample) 2018-07-31
EP3400287A1 (en) 2018-11-14
EP3400287B1 (en) 2020-12-30
NZ743682A (en) 2020-01-31
AU2017205925B2 (en) 2020-10-15
US12385010B2 (en) 2025-08-12
KR20180093967A (ko) 2018-08-22
BR112018013576A2 (pt) 2018-12-11
JP7159048B2 (ja) 2022-10-24

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