RU2730520C2 - Твердые формы альфа, омега дизамещенного дигидроксициклопентильного соединения и способы их получения и применения - Google Patents
Твердые формы альфа, омега дизамещенного дигидроксициклопентильного соединения и способы их получения и применения Download PDFInfo
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- RU2730520C2 RU2730520C2 RU2016123446A RU2016123446A RU2730520C2 RU 2730520 C2 RU2730520 C2 RU 2730520C2 RU 2016123446 A RU2016123446 A RU 2016123446A RU 2016123446 A RU2016123446 A RU 2016123446A RU 2730520 C2 RU2730520 C2 RU 2730520C2
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/559—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing hetero atoms other than oxygen
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/28—Halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
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- Public Health (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
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| US61/915,575 | 2013-12-13 | ||
| PCT/US2014/070156 WO2015089475A1 (en) | 2013-12-13 | 2014-12-12 | Solid forms of an alpha, omega di-substituted dihydroxy cyclopentyl compound and methods for the preparation and use thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12478503B2 (en) | 2009-05-18 | 2025-11-25 | Glaukos Corporation | Implants with controlled drug delivery features and methods of using same |
| US10206813B2 (en) | 2009-05-18 | 2019-02-19 | Dose Medical Corporation | Implants with controlled drug delivery features and methods of using same |
| EP3658149B1 (en) | 2017-07-25 | 2021-11-10 | Allergan, Inc. | Solid complex comprising (z)-7-((1r,2r,3r,5s)-2-((s,e)-5-(2,5-dichlorothiophen-3-yl)-3-hydroxypent-1-en-1-yl)-3,5-dihydroxycyclopentyl)hept-5-enamide, preparation and uses thereof |
| WO2021152473A1 (en) * | 2020-01-29 | 2021-08-05 | Kci Licensing, Inc. | Multiple fluid pathway connector with foam supports |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU645563A3 (ru) * | 1972-07-13 | 1979-01-30 | Пфайзер Инк (Фирма) | Способ получени промежуточных соединений дл получени простагландинов |
| US5296504A (en) * | 1988-09-06 | 1994-03-22 | Kabi Pharmacia | Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension |
| US6602900B2 (en) * | 1992-09-21 | 2003-08-05 | Allergan, Inc. | Cyclopentane heptan(ENE)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents |
| RU2217145C2 (ru) * | 1997-11-19 | 2003-11-27 | Аллерган Сэйлс, Инк. | 2-гетероарилалкенилпроизводные циклопентангептан(ен)овой кислоты |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5834498A (en) * | 1992-09-21 | 1998-11-10 | Allergan | Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents |
| ES2159734T3 (es) * | 1995-05-18 | 2001-10-16 | Allergan Sales Inc | Derivados 2-heteroarilalquenilicos del acido ciclopentano-heptan(en)oico como agentes terapeuticos para el tratamiento de la hipertension ocular. |
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2014
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- 2014-12-12 CA CA2933556A patent/CA2933556A1/en not_active Abandoned
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- 2014-12-12 WO PCT/US2014/070156 patent/WO2015089475A1/en not_active Ceased
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2016
- 2016-05-05 US US15/147,700 patent/US20170087163A1/en not_active Abandoned
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- 2016-06-10 CL CL2016001448A patent/CL2016001448A1/es unknown
- 2016-06-13 SA SA516371307A patent/SA516371307B1/ar unknown
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2019
- 2019-02-22 CL CL2019000471A patent/CL2019000471A1/es unknown
- 2019-12-23 JP JP2019231685A patent/JP2020073513A/ja active Pending
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2021
- 2021-06-08 IL IL283810A patent/IL283810A/en unknown
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU645563A3 (ru) * | 1972-07-13 | 1979-01-30 | Пфайзер Инк (Фирма) | Способ получени промежуточных соединений дл получени простагландинов |
| US5296504A (en) * | 1988-09-06 | 1994-03-22 | Kabi Pharmacia | Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension |
| US6602900B2 (en) * | 1992-09-21 | 2003-08-05 | Allergan, Inc. | Cyclopentane heptan(ENE)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents |
| RU2217145C2 (ru) * | 1997-11-19 | 2003-11-27 | Аллерган Сэйлс, Инк. | 2-гетероарилалкенилпроизводные циклопентангептан(ен)овой кислоты |
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| Mino R. Caira, "Crystalline Polymorphism of Organic Compounds", Topics in Current Chemistry, Vol. 198, рр.163-208,1998, DOI: 10,1007/3-540-69178-2_5. * |
| Химический энциклопедический словарь под редакцией И.Л. Кнунянца, М. "Советская * |
| Химический энциклопедический словарь под редакцией И.Л. Кнунянца, М. "Советская Энциклопедия", 1983, с.130-131. * |
Also Published As
| Publication number | Publication date |
|---|---|
| SA516371307B1 (ar) | 2018-10-04 |
| SG11201604787SA (en) | 2016-07-28 |
| JP2016539994A (ja) | 2016-12-22 |
| UA121108C2 (uk) | 2020-04-10 |
| AU2014361794B2 (en) | 2019-04-04 |
| CN105814033B (zh) | 2019-10-25 |
| US20150166504A1 (en) | 2015-06-18 |
| US9353079B2 (en) | 2016-05-31 |
| KR20160097310A (ko) | 2016-08-17 |
| CL2016001448A1 (es) | 2017-03-03 |
| IL245917B (en) | 2021-06-30 |
| MX2016007717A (es) | 2016-09-09 |
| BR112016013594A8 (pt) | 2020-05-19 |
| BR112016013594A2 (enExample) | 2017-08-08 |
| US20170087163A1 (en) | 2017-03-30 |
| JP2020073513A (ja) | 2020-05-14 |
| EP3080096A1 (en) | 2016-10-19 |
| IL283810A (en) | 2021-07-29 |
| IL245917A0 (en) | 2016-08-02 |
| CA2933556A1 (en) | 2015-06-18 |
| SG10201709702UA (en) | 2018-01-30 |
| WO2015089475A1 (en) | 2015-06-18 |
| CN105814033A (zh) | 2016-07-27 |
| AU2014361794A1 (en) | 2016-06-16 |
| CL2019000471A1 (es) | 2019-07-12 |
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