IL245917B - Solid forms of the compound alpha, omega-di-converted dihydroxy cyclopentyl and methods for their preparation and use - Google Patents

Solid forms of the compound alpha, omega-di-converted dihydroxy cyclopentyl and methods for their preparation and use

Info

Publication number
IL245917B
IL245917B IL245917A IL24591716A IL245917B IL 245917 B IL245917 B IL 245917B IL 245917 A IL245917 A IL 245917A IL 24591716 A IL24591716 A IL 24591716A IL 245917 B IL245917 B IL 245917B
Authority
IL
Israel
Prior art keywords
omega
alpha
preparation
methods
solid forms
Prior art date
Application number
IL245917A
Other languages
English (en)
Hebrew (he)
Other versions
IL245917A0 (en
Original Assignee
Allergan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allergan Inc filed Critical Allergan Inc
Publication of IL245917A0 publication Critical patent/IL245917A0/en
Publication of IL245917B publication Critical patent/IL245917B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/559Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing hetero atoms other than oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/28Halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL245917A 2013-12-13 2016-05-30 Solid forms of the compound alpha, omega-di-converted dihydroxy cyclopentyl and methods for their preparation and use IL245917B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361915575P 2013-12-13 2013-12-13
PCT/US2014/070156 WO2015089475A1 (en) 2013-12-13 2014-12-12 Solid forms of an alpha, omega di-substituted dihydroxy cyclopentyl compound and methods for the preparation and use thereof

Publications (2)

Publication Number Publication Date
IL245917A0 IL245917A0 (en) 2016-08-02
IL245917B true IL245917B (en) 2021-06-30

Family

ID=52282957

Family Applications (2)

Application Number Title Priority Date Filing Date
IL245917A IL245917B (en) 2013-12-13 2016-05-30 Solid forms of the compound alpha, omega-di-converted dihydroxy cyclopentyl and methods for their preparation and use
IL283810A IL283810A (en) 2013-12-13 2021-06-08 Solid forms of the compound alpha, omega-di-converted dihydroxy cyclopentyl and methods for their preparation and use

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL283810A IL283810A (en) 2013-12-13 2021-06-08 Solid forms of the compound alpha, omega-di-converted dihydroxy cyclopentyl and methods for their preparation and use

Country Status (16)

Country Link
US (2) US9353079B2 (enExample)
EP (1) EP3080096A1 (enExample)
JP (2) JP2016539994A (enExample)
KR (1) KR20160097310A (enExample)
CN (1) CN105814033B (enExample)
AU (1) AU2014361794B2 (enExample)
BR (1) BR112016013594A8 (enExample)
CA (1) CA2933556A1 (enExample)
CL (2) CL2016001448A1 (enExample)
IL (2) IL245917B (enExample)
MX (1) MX2016007717A (enExample)
RU (1) RU2730520C2 (enExample)
SA (1) SA516371307B1 (enExample)
SG (2) SG11201604787SA (enExample)
UA (1) UA121108C2 (enExample)
WO (1) WO2015089475A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12478503B2 (en) 2009-05-18 2025-11-25 Glaukos Corporation Implants with controlled drug delivery features and methods of using same
US10206813B2 (en) 2009-05-18 2019-02-19 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
EP3658149B1 (en) 2017-07-25 2021-11-10 Allergan, Inc. Solid complex comprising (z)-7-((1r,2r,3r,5s)-2-((s,e)-5-(2,5-dichlorothiophen-3-yl)-3-hydroxypent-1-en-1-yl)-3,5-dihydroxycyclopentyl)hept-5-enamide, preparation and uses thereof
WO2021152473A1 (en) * 2020-01-29 2021-08-05 Kci Licensing, Inc. Multiple fluid pathway connector with foam supports

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES416865A1 (es) * 1972-07-13 1976-03-01 Pfizer Procedimiento para preparar w-pentanorprostaglandinas sus- tituidas en la posicion 15.
US5296504A (en) * 1988-09-06 1994-03-22 Kabi Pharmacia Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
US6602900B2 (en) * 1992-09-21 2003-08-05 Allergan, Inc. Cyclopentane heptan(ENE)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
US5834498A (en) * 1992-09-21 1998-11-10 Allergan Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
US6124344A (en) * 1993-12-28 2000-09-26 Allergan Sales, Inc. Cyclopentane heptan(ene)oic acid, 2-heteroarylalkenyl derivatives as therapeutic agents
ES2159734T3 (es) * 1995-05-18 2001-10-16 Allergan Sales Inc Derivados 2-heteroarilalquenilicos del acido ciclopentano-heptan(en)oico como agentes terapeuticos para el tratamiento de la hipertension ocular.

Also Published As

Publication number Publication date
SA516371307B1 (ar) 2018-10-04
SG11201604787SA (en) 2016-07-28
RU2730520C2 (ru) 2020-08-24
JP2016539994A (ja) 2016-12-22
UA121108C2 (uk) 2020-04-10
AU2014361794B2 (en) 2019-04-04
CN105814033B (zh) 2019-10-25
US20150166504A1 (en) 2015-06-18
US9353079B2 (en) 2016-05-31
KR20160097310A (ko) 2016-08-17
CL2016001448A1 (es) 2017-03-03
MX2016007717A (es) 2016-09-09
BR112016013594A8 (pt) 2020-05-19
BR112016013594A2 (enExample) 2017-08-08
US20170087163A1 (en) 2017-03-30
JP2020073513A (ja) 2020-05-14
EP3080096A1 (en) 2016-10-19
IL283810A (en) 2021-07-29
IL245917A0 (en) 2016-08-02
CA2933556A1 (en) 2015-06-18
SG10201709702UA (en) 2018-01-30
WO2015089475A1 (en) 2015-06-18
CN105814033A (zh) 2016-07-27
AU2014361794A1 (en) 2016-06-16
CL2019000471A1 (es) 2019-07-12

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