RU2693484C1 - Антагонисты гастрина для лечения и профилактики остеопороза - Google Patents

Антагонисты гастрина для лечения и профилактики остеопороза Download PDF

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RU2693484C1
RU2693484C1 RU2016124538A RU2016124538A RU2693484C1 RU 2693484 C1 RU2693484 C1 RU 2693484C1 RU 2016124538 A RU2016124538 A RU 2016124538A RU 2016124538 A RU2016124538 A RU 2016124538A RU 2693484 C1 RU2693484 C1 RU 2693484C1
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gastrin
bone
hypergastrinemia
animals
cells
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RU2016124538A
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RU2016124538A (ru
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Марк КИДД
Ирвин Марк МОДЛИН
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СиЭль БАЙОСАЕНСИЗ ЭлЭлСи
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU2016124538A 2013-11-22 2014-11-21 Антагонисты гастрина для лечения и профилактики остеопороза RU2693484C1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361907980P 2013-11-22 2013-11-22
US61/907,980 2013-11-22
PCT/US2014/066832 WO2015077572A1 (en) 2013-11-22 2014-11-21 Gastrin antagonists (eg yf476, netazepide) for treatment and prevention of osteoporosis

Publications (2)

Publication Number Publication Date
RU2016124538A RU2016124538A (ru) 2017-12-27
RU2693484C1 true RU2693484C1 (ru) 2019-07-03

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RU2016124538A RU2693484C1 (ru) 2013-11-22 2014-11-21 Антагонисты гастрина для лечения и профилактики остеопороза

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Country Link
US (1) US10709714B2 (enExample)
EP (1) EP3071206B1 (enExample)
JP (1) JP6502939B2 (enExample)
KR (1) KR102254957B1 (enExample)
CN (1) CN106163527A (enExample)
AU (1) AU2014352875B2 (enExample)
BR (1) BR112016011727A2 (enExample)
CA (1) CA2929858C (enExample)
DK (1) DK3071206T3 (enExample)
ES (1) ES2870538T3 (enExample)
MX (1) MX2016006657A (enExample)
PL (1) PL3071206T3 (enExample)
RU (1) RU2693484C1 (enExample)
WO (1) WO2015077572A1 (enExample)

Families Citing this family (4)

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US10881667B2 (en) 2018-10-30 2021-01-05 City University Of Hong Kong Method and composition for treating epilepsy
US11285161B2 (en) 2019-04-26 2022-03-29 City University Of Hong Kong Method and composition for treating mental disorder and pain associated with nerve damage
CN110935005A (zh) * 2019-11-19 2020-03-31 宁波大学 一种丙谷二肽的新用途
CN115770266B (zh) * 2023-01-30 2023-05-09 云南中医药大学 一种用于治疗绝经后骨质疏松的药物组合物

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005007107A2 (en) * 2003-07-11 2005-01-27 University Of Massachusetts Histamine and cck2/gastrin receptor blockade in the treatment of acid-peptic disease and cancer
RU2379043C2 (ru) * 2007-08-02 2010-01-20 Закрытое акционерное общество "Биологические исследования и системы" Фармацевтическая композиция для профилактики и лечения остеопороза у женщин в период менопаузы

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RU2379043C2 (ru) * 2007-08-02 2010-01-20 Закрытое акционерное общество "Биологические исследования и системы" Фармацевтическая композиция для профилактики и лечения остеопороза у женщин в период менопаузы

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Title
BOYCE M. et al. "Single oral doses of netazepide (YF476), a gastrin receptor antagonist, cause dose-dependent, sustained increases in gastric pH compared with placebo and ranitidine in healthy subjects". Aliment Pharmacol Ther. 2012 Jul; 36(2):181-9. *
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SCHINKE T. et al. "Impaired gastric acidification negatively affects calcium homeostasis and bone mass". Nature Medicine, 2009, vol.15, no.6, pp.674-682. BOYCE M. et al. "Single oral doses of netazepide (YF476), a gastrin receptor antagonist, cause dose-dependent, sustained increases in gastric pH compared with placebo and ranitidine in healthy subjects". Aliment Pharmacol Ther. 2012 Jul; 36(2):181-9. *

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Publication number Publication date
BR112016011727A2 (pt) 2017-08-08
JP2016538295A (ja) 2016-12-08
WO2015077572A1 (en) 2015-05-28
RU2016124538A (ru) 2017-12-27
AU2014352875A1 (en) 2016-05-26
PL3071206T3 (pl) 2022-01-17
AU2014352875B2 (en) 2019-10-24
CN106163527A (zh) 2016-11-23
US20150148339A1 (en) 2015-05-28
EP3071206A1 (en) 2016-09-28
EP3071206B1 (en) 2021-02-17
ES2870538T3 (es) 2021-10-27
KR102254957B1 (ko) 2021-05-25
DK3071206T3 (da) 2021-05-25
CA2929858A1 (en) 2015-05-28
MX2016006657A (es) 2016-10-12
JP6502939B2 (ja) 2019-04-17
CA2929858C (en) 2022-03-29
AU2014352875A8 (en) 2016-06-30
US10709714B2 (en) 2020-07-14
KR20160088891A (ko) 2016-07-26

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