BR112016011727A2 - Antagonistas de gastrina para o tratamento e prevenção de osteoporose - Google Patents

Antagonistas de gastrina para o tratamento e prevenção de osteoporose

Info

Publication number
BR112016011727A2
BR112016011727A2 BR112016011727A BR112016011727A BR112016011727A2 BR 112016011727 A2 BR112016011727 A2 BR 112016011727A2 BR 112016011727 A BR112016011727 A BR 112016011727A BR 112016011727 A BR112016011727 A BR 112016011727A BR 112016011727 A2 BR112016011727 A2 BR 112016011727A2
Authority
BR
Brazil
Prior art keywords
gastrin
treatment
treating
osteoporosis
prevention
Prior art date
Application number
BR112016011727A
Other languages
English (en)
Inventor
Mark Modlin Irvin
KIDD Mark
Original Assignee
CL BioSciences LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52118000&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112016011727(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by CL BioSciences LLC filed Critical CL BioSciences LLC
Publication of BR112016011727A2 publication Critical patent/BR112016011727A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

ANTAGONISTAS DE GASTRINA PARA O TRATAMENTO E PREVENÇÃO DE OSTEOPOROSE. As modalidades fornecidas têm por base, em alguns aspectos, a demonstração no presente documento de uma função para gastrina na regulação do eixo intestino-ovário de envelhecimento e efeitos de alvejamento da atividade de gastrina na reversão de perda óssea mediada por gastrina. São fornecidos métodos, composições e agentes, que incluem antagonistas de gastrina, para o tratamento, melhora ou prevenção de afecções e doenças ósseas. Os métodos para o tratamento de uma afecção ou doença óssea associada à hipergastrinemia em um indivíduo que necessita desse tratamento, pode compreender a administração ao indivíduo de ao menos uma dose de uma quantidade terapeuticamente eficaz de um agente de alvejamento de receptor de gastrina, tratando, assim, a afecção ou doença óssea associada à hipergastrinemia.
BR112016011727A 2013-11-22 2014-11-21 Antagonistas de gastrina para o tratamento e prevenção de osteoporose BR112016011727A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361907980P 2013-11-22 2013-11-22
PCT/US2014/066832 WO2015077572A1 (en) 2013-11-22 2014-11-21 Gastrin antagonists (eg yf476, netazepide) for treatment and prevention of osteoporosis

Publications (1)

Publication Number Publication Date
BR112016011727A2 true BR112016011727A2 (pt) 2017-08-08

Family

ID=52118000

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112016011727A BR112016011727A2 (pt) 2013-11-22 2014-11-21 Antagonistas de gastrina para o tratamento e prevenção de osteoporose

Country Status (14)

Country Link
US (1) US10709714B2 (pt)
EP (1) EP3071206B1 (pt)
JP (1) JP6502939B2 (pt)
KR (1) KR102254957B1 (pt)
CN (1) CN106163527A (pt)
AU (1) AU2014352875B2 (pt)
BR (1) BR112016011727A2 (pt)
CA (1) CA2929858C (pt)
DK (1) DK3071206T3 (pt)
ES (1) ES2870538T3 (pt)
MX (1) MX2016006657A (pt)
PL (1) PL3071206T3 (pt)
RU (1) RU2693484C1 (pt)
WO (1) WO2015077572A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10881667B2 (en) 2018-10-30 2021-01-05 City University Of Hong Kong Method and composition for treating epilepsy
US11285161B2 (en) 2019-04-26 2022-03-29 City University Of Hong Kong Method and composition for treating mental disorder and pain associated with nerve damage
CN110935005A (zh) * 2019-11-19 2020-03-31 宁波大学 一种丙谷二肽的新用途
CN115770266B (zh) * 2023-01-30 2023-05-09 云南中医药大学 一种用于治疗绝经后骨质疏松的药物组合物

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Also Published As

Publication number Publication date
AU2014352875A8 (en) 2016-06-30
AU2014352875A1 (en) 2016-05-26
PL3071206T3 (pl) 2022-01-17
ES2870538T3 (es) 2021-10-27
KR102254957B1 (ko) 2021-05-25
CN106163527A (zh) 2016-11-23
MX2016006657A (es) 2016-10-12
CA2929858C (en) 2022-03-29
JP2016538295A (ja) 2016-12-08
JP6502939B2 (ja) 2019-04-17
WO2015077572A1 (en) 2015-05-28
EP3071206B1 (en) 2021-02-17
AU2014352875B2 (en) 2019-10-24
EP3071206A1 (en) 2016-09-28
US10709714B2 (en) 2020-07-14
DK3071206T3 (da) 2021-05-25
RU2693484C1 (ru) 2019-07-03
US20150148339A1 (en) 2015-05-28
KR20160088891A (ko) 2016-07-26
CA2929858A1 (en) 2015-05-28
RU2016124538A (ru) 2017-12-27

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