PL3071206T3 - Antagoniści gastryny (eg yf476, netazepid) do leczenia i zapobiegania osteoporozie - Google Patents

Antagoniści gastryny (eg yf476, netazepid) do leczenia i zapobiegania osteoporozie

Info

Publication number
PL3071206T3
PL3071206T3 PL14815149T PL14815149T PL3071206T3 PL 3071206 T3 PL3071206 T3 PL 3071206T3 PL 14815149 T PL14815149 T PL 14815149T PL 14815149 T PL14815149 T PL 14815149T PL 3071206 T3 PL3071206 T3 PL 3071206T3
Authority
PL
Poland
Prior art keywords
netazepide
osteoporosis
prevention
treatment
gastrin antagonists
Prior art date
Application number
PL14815149T
Other languages
English (en)
Inventor
Irvin Mark MODLIN
Mark Kidd
Original Assignee
CL BioSciences LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52118000&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3071206(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by CL BioSciences LLC filed Critical CL BioSciences LLC
Publication of PL3071206T3 publication Critical patent/PL3071206T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL14815149T 2013-11-22 2014-11-21 Antagoniści gastryny (eg yf476, netazepid) do leczenia i zapobiegania osteoporozie PL3071206T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361907980P 2013-11-22 2013-11-22
PCT/US2014/066832 WO2015077572A1 (en) 2013-11-22 2014-11-21 Gastrin antagonists (eg yf476, netazepide) for treatment and prevention of osteoporosis
EP14815149.1A EP3071206B1 (en) 2013-11-22 2014-11-21 Gastrin antagonists (eg yf476, netazepide) for treatment and prevention of osteoporosis

Publications (1)

Publication Number Publication Date
PL3071206T3 true PL3071206T3 (pl) 2022-01-17

Family

ID=52118000

Family Applications (1)

Application Number Title Priority Date Filing Date
PL14815149T PL3071206T3 (pl) 2013-11-22 2014-11-21 Antagoniści gastryny (eg yf476, netazepid) do leczenia i zapobiegania osteoporozie

Country Status (14)

Country Link
US (1) US10709714B2 (pl)
EP (1) EP3071206B1 (pl)
JP (1) JP6502939B2 (pl)
KR (1) KR102254957B1 (pl)
CN (1) CN106163527A (pl)
AU (1) AU2014352875B2 (pl)
BR (1) BR112016011727A2 (pl)
CA (1) CA2929858C (pl)
DK (1) DK3071206T3 (pl)
ES (1) ES2870538T3 (pl)
MX (1) MX2016006657A (pl)
PL (1) PL3071206T3 (pl)
RU (1) RU2693484C1 (pl)
WO (1) WO2015077572A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10881667B2 (en) 2018-10-30 2021-01-05 City University Of Hong Kong Method and composition for treating epilepsy
US11285161B2 (en) 2019-04-26 2022-03-29 City University Of Hong Kong Method and composition for treating mental disorder and pain associated with nerve damage
CN110935005A (zh) * 2019-11-19 2020-03-31 宁波大学 一种丙谷二肽的新用途
CN115770266B (zh) * 2023-01-30 2023-05-09 云南中医药大学 一种用于治疗绝经后骨质疏松的药物组合物

Family Cites Families (95)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0348523A4 (en) 1987-12-22 1991-10-09 Yoshitomi Pharmaceutical Industries, Ltd. Thienodiazepine compounds and their medicinal use
EP0411668B2 (en) 1989-08-04 1998-11-11 MERCK SHARP & DOHME LTD. Central cholecystokinin antagonists for treatment of psychiatric disorders
US5399565A (en) 1990-07-17 1995-03-21 Eli Lilly And Company Pyrazolidinone CCK and gastrin antagonists and pharmaceutical formulations therof
WO1992011246A1 (en) 1990-12-25 1992-07-09 Yamanouchi Pharmaceutical Co., Ltd. Novel benzodiazepine derivative
AU665562B2 (en) 1991-07-12 1996-01-11 Warner-Lambert Company Cholecystokinin antagonists useful in the treatment of panic attacks
WO1993007129A1 (fr) * 1991-10-11 1993-04-15 Yoshitomi Pharmaceutical Industries, Ltd. Medicament utilise pour traiter l'osteoporose et compose de diazepine
AU3247593A (en) 1991-12-20 1993-07-28 Warner-Lambert Company Therapeutic combinations useful in the treatment of gastroesophageal reflux disease
IL104853A (en) 1992-02-27 1997-11-20 Yamanouchi Pharma Co Ltd Benzodiazepine derivatives, their preparation and pharmaceutical compositions containing them
TW281669B (pl) 1993-02-17 1996-07-21 Chugai Pharmaceutical Co Ltd
GB2282595A (en) 1993-08-25 1995-04-12 Yamanouchi Pharma Co Ltd Benzodiazepine derivatives
IT1261255B (it) 1993-09-09 1996-05-09 Rotta Research Lab Derivati acidi poliamidici ad attivita' antigastrinica, procedimento per la loro preparazione e loro uso farmaceutico.
AU715611B2 (en) 1995-12-11 2000-02-03 New England Medical Center Hospitals, Inc., The Assay for and uses of peptide hormone receptor ligands
US5750353A (en) 1995-12-11 1998-05-12 New England Medical Center Hospitals, Inc. Assay for non-peptide agonists to peptide hormone receptors
US5922883A (en) 1996-04-03 1999-07-13 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US20040001842A1 (en) 1997-05-12 2004-01-01 Dov Michaeli Immunogenic compositions to the CCK-B/gastrin receptor and methods for the treatment of tumors
PT981369E (pt) 1997-05-12 2005-03-31 Aphton Corp Composicoes imunogenicas para o receptor de cck-b/gastrina e metodos para o tratamento de tumores
PL193109B1 (pl) 1998-05-15 2007-01-31 Aphton Corp Kombinacja obejmująca immunogen zawierający peptyd imitujący immunologicznie gastrynę G17 oraz jeden lub więcej środków chemioterapeutycznych oraz jej zastosowanie
US6232320B1 (en) 1998-06-04 2001-05-15 Abbott Laboratories Cell adhesion-inhibiting antiinflammatory compounds
IL139811A0 (en) 1998-06-04 2002-02-10 Abbott Lab Cell adhesion-inhibiting antinflammatory compounds
US6362371B1 (en) 1998-06-08 2002-03-26 Advanced Medicine, Inc. β2- adrenergic receptor agonists
WO2000044722A1 (en) 1999-01-29 2000-08-03 Chugai Seiyaku Kabushiki Kaisha Chondrongenesis promotors and indolin-2-one derivatives
HK1045306A1 (zh) 1999-06-03 2002-11-22 Abbott Laboratories 抑制细胞黏附的抗炎化合物
US20030191279A1 (en) 1999-08-27 2003-10-09 Goldstein Steven Wayne Urea derivatives useful as anticancer agents
US6844367B1 (en) 1999-09-17 2005-01-18 Millennium Pharmaceuticals, Inc. Benzamides and related inhibitors of factor Xa
HUP0203183A3 (en) 1999-11-05 2006-02-28 Sod Conseils Rech Applic Novel heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use
WO2001035899A2 (en) 1999-11-19 2001-05-25 Axxima Pharmaceuticals Ag Inhibitors of helicobacter pylori induced gastrointestinal diseases
WO2001077685A2 (en) 2000-04-10 2001-10-18 The General Hospital Corporation Diagnosis and treatment of gastrointestinal disease
AU2001273040A1 (en) 2000-06-27 2002-01-08 Du Pont Pharmaceuticals Company Factor xa inhibitors
AU2002252456A1 (en) 2001-03-23 2002-10-08 Aphton Corporation Combination treatment of pancreatic cancer
US20040138285A1 (en) 2001-04-27 2004-07-15 Makoto Okazaki Chondrogenesis promoters
US20090191232A1 (en) 2001-05-04 2009-07-30 Gevas Philip C Combination therapy for the treatment of tumors
JPWO2002092096A1 (ja) 2001-05-11 2004-08-26 山之内製薬株式会社 抗腫瘍剤
AUPR738301A0 (en) 2001-08-30 2001-09-20 Starpharma Limited Chemotherapeutic agents
ATE293449T1 (de) 2001-11-13 2005-05-15 Black James Foundation Benzotriazepine als gastrin und cholecystokinin rezeptor liganden
JP2005529850A (ja) 2002-02-19 2005-10-06 ファルマシア・イタリア・エス・ピー・エー 三環系ピラゾール誘導体、その製造方法および抗腫瘍剤としてのその使用
DE10207037A1 (de) 2002-02-20 2003-08-28 Bayer Cropscience Gmbh 2-Amino-4-bicyclyamino-6H-1,3.5-triazine, Verfahren zu deren Herstellung und deren Verwendung als Herbizide und Pflanzenwachstumsregulatoren
UA79804C2 (en) 2002-07-03 2007-07-25 Janssen Pharmaceutica Nv Cck-1 receptor modulators
US20030049698A1 (en) 2002-10-08 2003-03-13 Wang Timothy C. Diagnosis and treatment of gastrointestinal disease
MXPA05010484A (es) 2003-03-28 2006-03-10 Johnson & Johnson Compuestos de benzo[1,2,5]tiadiazole.
GB0310865D0 (en) 2003-05-12 2003-06-18 Black James Foundation Gastrin and cholecystokinin receptor ligands
US7524837B2 (en) 2003-05-12 2009-04-28 Janssen Pharmaceutica N.V. Benzotriazapinone salts and methods for using same
US20050042283A1 (en) 2003-07-11 2005-02-24 University Of Massachusetts Histamine and CCK2/gastrin receptor blockade in the treatment of acid-peptic disease and cancer
EP1651621B1 (en) 2003-08-08 2008-08-06 Janssen Pharmaceutica N.V. 2- (quinoxalin-5-ylsulfonylamino) -benzamide compounds as cck2 modulators
US20070293482A1 (en) 2004-03-19 2007-12-20 Novartis Pharmaceuticals Corporation Process for Preparing Benzodiazepines
US7429604B2 (en) 2004-06-15 2008-09-30 Bristol Myers Squibb Company Six-membered heterocycles useful as serine protease inhibitors
US7947833B2 (en) 2004-08-04 2011-05-24 Janssen Pharmaceutica Nv Preparation of quinoxaline compounds
CN101061116A (zh) 2004-09-24 2007-10-24 詹森药业有限公司 磺酰胺化合物
WO2006044352A2 (en) 2004-10-12 2006-04-27 Janssen Pharmaceutica N.V. Canine cholecystokinin 1 receptor materials and their use
US20090239841A1 (en) 2004-10-27 2009-09-24 Hutchison Alan J Diaryl Ureas as CB1 Antagonists
EP1807390A4 (en) 2004-11-04 2008-07-02 Neurogen Corp ARYL ALKYL UREA AS CB1 ANTAGONISTS
GB0425196D0 (en) 2004-11-15 2004-12-15 Black James Foundation Gastrin and cholecystokinin receptor ligands
EP1838309B1 (en) 2004-12-17 2008-08-20 Pfizer, Inc. Chromane derivatives useful as acid pump antagonists
PL1839662T3 (pl) 2005-01-19 2010-08-31 Zeria Pharm Co Ltd Środek przeciwnowotworowy
AR053713A1 (es) 2005-04-20 2007-05-16 Xenon Pharmaceuticals Inc Compuestos heterociclicos y sus usos como agentes terapeuticos
JP5197361B2 (ja) 2005-06-06 2013-05-15 ザ ボード オブ トラスティーズ オブ ザ ユニヴァーシティー オブ イリノイ 睡眠障害を処置するための組成物および方法
CA2608582A1 (en) 2005-06-14 2006-12-21 Pfizer Inc. Chromane substituted benzimidazole derivatives as acid pump antagonists
ES2324354T3 (es) 2005-07-29 2009-08-05 Rottapharm S.P.A. Combinacion terapeutica de itriglumida e inhibidores de la bomba de protones en el tratamiento de trastornos gastrointestinales y relacionados.
WO2007026218A2 (en) 2005-09-01 2007-03-08 Pfizer Japan Inc. Chromane substituted 2-alkyl imidazopyridine derivatives and use thereof as acid pump antagonists
WO2007031860A1 (en) 2005-09-15 2007-03-22 Pfizer Japan Inc. Indane substituted benzimidazoles and their use as acid pump inhibitors
EP1963311B1 (en) 2005-12-19 2010-06-16 RaQualia Pharma Inc Chromane substituted benzimidazoles and their use as acid pump inhibitors
WO2007072142A2 (en) 2005-12-19 2007-06-28 Pfizer Japan Inc. Benzimidazole-5-carboxamide derivatives
WO2007107827A1 (en) 2006-03-17 2007-09-27 Raqualia Pharma Inc. Chromane derivatives
AU2007236321A1 (en) 2006-04-12 2007-10-18 Merck Patent Gmbh N-oxides of heterocyclic substituted bisarylureas for treating kinase-mediated diseases
FR2901473B1 (fr) 2006-05-24 2010-08-13 Oreal Procede de defrisage des fibres keratiniques avec un moyen de chauffage et une amide
FR2901472B1 (fr) 2006-05-24 2010-08-13 Oreal Procede de defrisage des fibres keratiniques avec un moyen de chauffage et des agents denaturants
EP2081939B1 (en) 2006-09-21 2011-06-15 RaQualia Pharma Inc Benzimidazole derivatives as selective acid pump inhibitors
WO2008046082A2 (en) 2006-10-12 2008-04-17 Xenon Pharmaceuticals Inc. Use of heterocyclic compounds as therapeutic agents
WO2008059373A1 (en) 2006-11-17 2008-05-22 Raqualia Pharma Inc. Imidazo [1, 2-a] pyrazine derivatives and their use as acid pump antagonists
JP2008222557A (ja) 2007-03-08 2008-09-25 Kotobuki Seiyaku Kk ピロロ[3,2−d]ピリミジン誘導体及びこれを有効成分とする医薬組成物
WO2008114123A1 (en) 2007-03-21 2008-09-25 Raqualia Pharma Inc. Spiro benzimidazole derivatives as acid pump inhibitors
WO2008124518A1 (en) 2007-04-03 2008-10-16 Janssen Pharmaceutica N.V. Oxo-dihydroisoindole sulfonamide compounds as modulators of the cck2 receptor
WO2008124524A2 (en) 2007-04-03 2008-10-16 Janssen Pharmaceutica N.V. Aryl sulfonamide compounds as modulators of the cck2 receptor
MX2009013753A (es) 2007-06-26 2010-01-26 Sanofi Aventis Una sintesis regioselectiva catalizada por cobre de bencimidazoles y azabencimidazoles.
RU2379043C2 (ru) 2007-08-02 2010-01-20 Закрытое акционерное общество "Биологические исследования и системы" Фармацевтическая композиция для профилактики и лечения остеопороза у женщин в период менопаузы
US20110105515A1 (en) 2007-08-07 2011-05-05 President And Fellows Of Harvard College Targeting the oncoprotein nucleophosmin
TW201011009A (en) 2008-09-15 2010-03-16 Priaxon Ag Novel pyrrolidin-2-ones
WO2010036316A1 (en) 2008-09-24 2010-04-01 Yangbo Feng Urea and carbamate compounds and analogs as kinase inhibitors
EP2415766A4 (en) 2009-03-31 2012-11-21 Zeria Pharm Co Ltd METHOD FOR PRODUCING A BENZODIAZEPINE DERIVATIVE
KR101605063B1 (ko) 2009-07-09 2016-03-21 라퀄리아 파마 인코포레이티드 소화관 운동이상이 관여하는 질환의 치료용 산 펌프 길항제
CA2775204A1 (en) 2009-09-24 2011-03-31 Centro Nacional De Investigaciones Oncologicas (Cnio) Fused imidazo [3, 2 - d] pyraz ines as pi3 kinase inhibitors
CA2776690C (en) 2009-10-06 2020-05-12 Millennium Pharmaceuticals, Inc. Heterocyclic compounds useful as pdk1 inhibitors
AU2010319298B2 (en) 2009-11-13 2015-11-05 Plastipak Packaging, Inc. Oxygen scavengers, compositions comprising the scavengers, and articles made from the compositions
WO2011063164A2 (en) 2009-11-18 2011-05-26 Steady Sleep Rx Co., Inc. Sustained release cannabinoid medicaments
MX2012012353A (es) 2010-04-23 2013-02-07 Kineta Inc Compuestos anti-virales.
US9000054B2 (en) 2010-08-12 2015-04-07 Senomyx, Inc. Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer
US20120231083A1 (en) 2010-11-18 2012-09-13 The Board Of Trustees Of The University Of Illinois Sustained release cannabinoid medicaments
AU2011329623A1 (en) 2010-11-18 2013-07-11 Pier Pharmaceuticals Low dose cannabinoid medicaments
AU2011343039B2 (en) 2010-12-14 2017-03-02 Electrophoretics Limited Casein kinase 1delta (CK1delta) inhibitors
WO2013017479A1 (en) 2011-07-29 2013-02-07 Cellzome Limited Pyrazolo[4,3-c]pyridine derivatives as jak inhibitors
WO2013017480A1 (en) 2011-07-29 2013-02-07 Cellzome Limited Pyrazolo[4,3-c]pyridine derivatives as jak inhibitors
BR112014010951B1 (pt) 2011-11-07 2020-12-08 Trustees Of Boston College composto e uso do referido composto
WO2013126797A1 (en) 2012-02-24 2013-08-29 Purdue Research Foundation Cholecystokinin b receptor targeting for imaging and therapy
WO2013158928A2 (en) 2012-04-18 2013-10-24 Elcelyx Therapeutics, Inc. Chemosensory receptor ligand-based therapies
TWI610916B (zh) 2012-08-03 2018-01-11 廣東東陽光藥業有限公司 作爲丙型肝炎抑制劑的橋環化合物及其在藥物中的應用
US8952009B2 (en) 2012-08-06 2015-02-10 Amgen Inc. Chroman derivatives as TRPM8 inhibitors

Also Published As

Publication number Publication date
AU2014352875A1 (en) 2016-05-26
EP3071206A1 (en) 2016-09-28
RU2016124538A (ru) 2017-12-27
DK3071206T3 (da) 2021-05-25
RU2693484C1 (ru) 2019-07-03
CA2929858A1 (en) 2015-05-28
CN106163527A (zh) 2016-11-23
AU2014352875A8 (en) 2016-06-30
US10709714B2 (en) 2020-07-14
ES2870538T3 (es) 2021-10-27
WO2015077572A1 (en) 2015-05-28
JP6502939B2 (ja) 2019-04-17
JP2016538295A (ja) 2016-12-08
AU2014352875B2 (en) 2019-10-24
BR112016011727A2 (pt) 2017-08-08
KR102254957B1 (ko) 2021-05-25
KR20160088891A (ko) 2016-07-26
CA2929858C (en) 2022-03-29
MX2016006657A (es) 2016-10-12
US20150148339A1 (en) 2015-05-28
EP3071206B1 (en) 2021-02-17

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