RU2635564C2 - Композиция для лечения гипертензии и/или фиброза - Google Patents

Композиция для лечения гипертензии и/или фиброза Download PDF

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Publication number
RU2635564C2
RU2635564C2 RU2016112257A RU2016112257A RU2635564C2 RU 2635564 C2 RU2635564 C2 RU 2635564C2 RU 2016112257 A RU2016112257 A RU 2016112257A RU 2016112257 A RU2016112257 A RU 2016112257A RU 2635564 C2 RU2635564 C2 RU 2635564C2
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Prior art keywords
fibrosis
compound
present
pharmaceutically acceptable
subject
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RU2016112257A
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English (en)
Russian (ru)
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RU2016112257A (ru
Inventor
Карен Аннетт ДАГГЕН
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Вектус Байосистемс Лимитед
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Priority claimed from AU2013903573A external-priority patent/AU2013903573A0/en
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09Geometrical isomers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
RU2016112257A 2013-09-17 2014-09-17 Композиция для лечения гипертензии и/или фиброза RU2635564C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2013903573A AU2013903573A0 (en) 2013-09-17 Compositions for the treatment of hypertension and/or fibrosis
AU2013903573 2013-09-17
PCT/AU2014/000923 WO2015039173A1 (en) 2013-09-17 2014-09-17 Compositions for the treatment of hypertension and/or fibrosis

Publications (2)

Publication Number Publication Date
RU2016112257A RU2016112257A (ru) 2017-10-20
RU2635564C2 true RU2635564C2 (ru) 2017-11-14

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RU2016112257A RU2635564C2 (ru) 2013-09-17 2014-09-17 Композиция для лечения гипертензии и/или фиброза

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US (1) US9458093B2 (enExample)
EP (1) EP3046901B1 (enExample)
JP (1) JP6122548B2 (enExample)
KR (1) KR101736416B1 (enExample)
CN (1) CN105683152B (enExample)
AP (1) AP2016009079A0 (enExample)
AU (1) AU2014324078B2 (enExample)
BR (1) BR112016005601B1 (enExample)
CA (1) CA2924356C (enExample)
DK (1) DK3046901T3 (enExample)
ES (1) ES2655455T3 (enExample)
IL (1) IL244621A (enExample)
MX (1) MX368865B (enExample)
MY (1) MY172557A (enExample)
NO (1) NO3046901T3 (enExample)
NZ (1) NZ717927A (enExample)
PH (1) PH12016500497B1 (enExample)
PL (1) PL3046901T3 (enExample)
RU (1) RU2635564C2 (enExample)
SG (1) SG11201601642WA (enExample)
UA (1) UA118111C2 (enExample)
WO (1) WO2015039173A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2712140C2 (ru) * 2015-03-18 2020-01-24 Вектус Байосистемс Лимитед Композиции для лечения фиброза и связанных с фиброзом состояний

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3284981B2 (ja) 1998-11-02 2002-05-27 株式会社デンソー 車両用交流発電機およびそのステータの製造方法
US9956166B2 (en) 2013-09-18 2018-05-01 Sorrento Therapeutics, Inc. Methods for administration and methods for treating cardiovascular diseases with resiniferatoxin
JP6716598B2 (ja) * 2015-03-18 2020-07-01 ヴェクタス バイオシステムズ リミテッド 腎臓及び/又は肝臓疾患を治療するための組成物
WO2017049343A1 (en) 2015-09-22 2017-03-30 Vectus Biosystems Limited Synthesis of terphenyl compounds
CN109562096A (zh) * 2016-04-13 2019-04-02 内布拉斯加大学董事会 施用树脂毒素的方法和用树脂毒素治疗心血管疾病的方法
WO2018018091A1 (en) 2016-07-28 2018-02-01 Vectus Biosystems Limited Compositions for the treatment of pulmonary fibrosis

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2090552C1 (ru) * 1992-06-30 1997-09-20 Рон-Пуленк Агрошими Производные фенилбензамидов, способы их получения, фунгицидная композиция для защиты растений и способ борьбы с фунгицидными заболеваниями
WO2005120545A1 (en) * 2004-06-11 2005-12-22 Vectus Biosystems Limited Compositions and methods for treatment of cardiovascular disease
US20110082109A1 (en) * 2009-10-02 2011-04-07 Ajinomoto Co., Inc. Novel acyl guanidine derivatives
WO2015039172A1 (en) * 2013-09-17 2015-03-26 Vectus Biosystems Pty Ltd Compositions for the treatment of hypertension and/or fibrosis

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2466738C2 (ru) * 2005-12-09 2012-11-20 Вектас Байосистемз Лимитед Фрагменты vip и способы их применения

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2090552C1 (ru) * 1992-06-30 1997-09-20 Рон-Пуленк Агрошими Производные фенилбензамидов, способы их получения, фунгицидная композиция для защиты растений и способ борьбы с фунгицидными заболеваниями
WO2005120545A1 (en) * 2004-06-11 2005-12-22 Vectus Biosystems Limited Compositions and methods for treatment of cardiovascular disease
US20110082109A1 (en) * 2009-10-02 2011-04-07 Ajinomoto Co., Inc. Novel acyl guanidine derivatives
WO2015039172A1 (en) * 2013-09-17 2015-03-26 Vectus Biosystems Pty Ltd Compositions for the treatment of hypertension and/or fibrosis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MARTIN PETERS et al. "A modular synthesis of teraryl-based α-Helix mimetics, Part 1: Synthesis of core fragments with two electronically differentiated leaving groups", CHEMISTRY-A EUROPEAN JOURNAL, 2013, vol.19, p.2442-2449. *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2712140C2 (ru) * 2015-03-18 2020-01-24 Вектус Байосистемс Лимитед Композиции для лечения фиброза и связанных с фиброзом состояний

Also Published As

Publication number Publication date
AU2014324078A1 (en) 2016-04-07
CA2924356A1 (en) 2015-03-26
EP3046901A1 (en) 2016-07-27
EP3046901B1 (en) 2017-10-18
PH12016500497A1 (en) 2016-06-13
SG11201601642WA (en) 2016-04-28
IL244621A (en) 2017-04-30
AU2014324078B2 (en) 2016-12-15
ES2655455T3 (es) 2018-02-20
BR112016005601A8 (pt) 2020-02-18
RU2016112257A (ru) 2017-10-20
UA118111C2 (uk) 2018-11-26
CN105683152A (zh) 2016-06-15
DK3046901T3 (en) 2018-01-02
BR112016005601B1 (pt) 2021-02-02
CN105683152B (zh) 2017-03-22
PL3046901T3 (pl) 2018-03-30
WO2015039173A1 (en) 2015-03-26
JP2016532632A (ja) 2016-10-20
NZ717927A (en) 2018-12-21
JP6122548B2 (ja) 2017-04-26
MX368865B (es) 2019-08-02
KR20160074471A (ko) 2016-06-28
MX2016003371A (es) 2016-10-21
IL244621A0 (en) 2016-04-21
KR101736416B1 (ko) 2017-05-16
US20160221933A1 (en) 2016-08-04
PH12016500497B1 (en) 2017-12-13
EP3046901A4 (en) 2017-04-12
CA2924356C (en) 2018-04-03
NO3046901T3 (enExample) 2018-03-17
US9458093B2 (en) 2016-10-04
AP2016009079A0 (en) 2016-03-31
MY172557A (en) 2019-12-02

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