RU2635564C2 - Композиция для лечения гипертензии и/или фиброза - Google Patents

Композиция для лечения гипертензии и/или фиброза Download PDF

Info

Publication number
RU2635564C2
RU2635564C2 RU2016112257A RU2016112257A RU2635564C2 RU 2635564 C2 RU2635564 C2 RU 2635564C2 RU 2016112257 A RU2016112257 A RU 2016112257A RU 2016112257 A RU2016112257 A RU 2016112257A RU 2635564 C2 RU2635564 C2 RU 2635564C2
Authority
RU
Russia
Prior art keywords
fibrosis
compound
present
pharmaceutically acceptable
subject
Prior art date
Application number
RU2016112257A
Other languages
English (en)
Russian (ru)
Other versions
RU2016112257A (ru
Inventor
Карен Аннетт ДАГГЕН
Original Assignee
Вектус Байосистемс Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2013903573A external-priority patent/AU2013903573A0/en
Application filed by Вектус Байосистемс Лимитед filed Critical Вектус Байосистемс Лимитед
Publication of RU2016112257A publication Critical patent/RU2016112257A/ru
Application granted granted Critical
Publication of RU2635564C2 publication Critical patent/RU2635564C2/ru

Links

Images

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09Geometrical isomers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
RU2016112257A 2013-09-17 2014-09-17 Композиция для лечения гипертензии и/или фиброза RU2635564C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2013903573A AU2013903573A0 (en) 2013-09-17 Compositions for the treatment of hypertension and/or fibrosis
AU2013903573 2013-09-17
PCT/AU2014/000923 WO2015039173A1 (en) 2013-09-17 2014-09-17 Compositions for the treatment of hypertension and/or fibrosis

Publications (2)

Publication Number Publication Date
RU2016112257A RU2016112257A (ru) 2017-10-20
RU2635564C2 true RU2635564C2 (ru) 2017-11-14

Family

ID=52687998

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2016112257A RU2635564C2 (ru) 2013-09-17 2014-09-17 Композиция для лечения гипертензии и/или фиброза

Country Status (22)

Country Link
US (1) US9458093B2 (enExample)
EP (1) EP3046901B1 (enExample)
JP (1) JP6122548B2 (enExample)
KR (1) KR101736416B1 (enExample)
CN (1) CN105683152B (enExample)
AP (1) AP2016009079A0 (enExample)
AU (1) AU2014324078B2 (enExample)
BR (1) BR112016005601B1 (enExample)
CA (1) CA2924356C (enExample)
DK (1) DK3046901T3 (enExample)
ES (1) ES2655455T3 (enExample)
IL (1) IL244621A (enExample)
MX (1) MX368865B (enExample)
MY (1) MY172557A (enExample)
NO (1) NO3046901T3 (enExample)
NZ (1) NZ717927A (enExample)
PH (1) PH12016500497B1 (enExample)
PL (1) PL3046901T3 (enExample)
RU (1) RU2635564C2 (enExample)
SG (1) SG11201601642WA (enExample)
UA (1) UA118111C2 (enExample)
WO (1) WO2015039173A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2712140C2 (ru) * 2015-03-18 2020-01-24 Вектус Байосистемс Лимитед Композиции для лечения фиброза и связанных с фиброзом состояний

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3284981B2 (ja) 1998-11-02 2002-05-27 株式会社デンソー 車両用交流発電機およびそのステータの製造方法
US9956166B2 (en) 2013-09-18 2018-05-01 Sorrento Therapeutics, Inc. Methods for administration and methods for treating cardiovascular diseases with resiniferatoxin
CN107614484B (zh) 2015-03-18 2020-09-25 维克图斯生物系统有限公司 用于治疗肾脏和/或肝脏疾病的组合物
EP3353147B1 (en) * 2015-09-22 2021-01-13 Vectus Biosystems Limited Synthesis of terphenyl compounds
KR102395342B1 (ko) * 2016-04-13 2022-05-10 보드 오브 리젠츠 오브 디 유니버시티 오브 네브라스카 레시니페라톡신을 사용한 투여 방법 및 심혈관 질환을 치료하는 방법
NZ750495A (en) * 2016-07-28 2022-07-01 Vectus Biosystems Ltd Compositions for the treatment of pulmonary fibrosis

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2090552C1 (ru) * 1992-06-30 1997-09-20 Рон-Пуленк Агрошими Производные фенилбензамидов, способы их получения, фунгицидная композиция для защиты растений и способ борьбы с фунгицидными заболеваниями
WO2005120545A1 (en) * 2004-06-11 2005-12-22 Vectus Biosystems Limited Compositions and methods for treatment of cardiovascular disease
US20110082109A1 (en) * 2009-10-02 2011-04-07 Ajinomoto Co., Inc. Novel acyl guanidine derivatives
WO2015039172A1 (en) * 2013-09-17 2015-03-26 Vectus Biosystems Pty Ltd Compositions for the treatment of hypertension and/or fibrosis

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ569401A (en) * 2005-12-09 2012-03-30 Vectus Biosystems Ltd VIP fragments and methods of use

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2090552C1 (ru) * 1992-06-30 1997-09-20 Рон-Пуленк Агрошими Производные фенилбензамидов, способы их получения, фунгицидная композиция для защиты растений и способ борьбы с фунгицидными заболеваниями
WO2005120545A1 (en) * 2004-06-11 2005-12-22 Vectus Biosystems Limited Compositions and methods for treatment of cardiovascular disease
US20110082109A1 (en) * 2009-10-02 2011-04-07 Ajinomoto Co., Inc. Novel acyl guanidine derivatives
WO2015039172A1 (en) * 2013-09-17 2015-03-26 Vectus Biosystems Pty Ltd Compositions for the treatment of hypertension and/or fibrosis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MARTIN PETERS et al. "A modular synthesis of teraryl-based α-Helix mimetics, Part 1: Synthesis of core fragments with two electronically differentiated leaving groups", CHEMISTRY-A EUROPEAN JOURNAL, 2013, vol.19, p.2442-2449. *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2712140C2 (ru) * 2015-03-18 2020-01-24 Вектус Байосистемс Лимитед Композиции для лечения фиброза и связанных с фиброзом состояний

Also Published As

Publication number Publication date
UA118111C2 (uk) 2018-11-26
NZ717927A (en) 2018-12-21
CN105683152A (zh) 2016-06-15
CA2924356C (en) 2018-04-03
US9458093B2 (en) 2016-10-04
AP2016009079A0 (en) 2016-03-31
AU2014324078A1 (en) 2016-04-07
EP3046901B1 (en) 2017-10-18
NO3046901T3 (enExample) 2018-03-17
MX368865B (es) 2019-08-02
IL244621A (en) 2017-04-30
CA2924356A1 (en) 2015-03-26
ES2655455T3 (es) 2018-02-20
MY172557A (en) 2019-12-02
AU2014324078B2 (en) 2016-12-15
IL244621A0 (en) 2016-04-21
BR112016005601B1 (pt) 2021-02-02
PH12016500497B1 (en) 2017-12-13
PH12016500497A1 (en) 2016-06-13
SG11201601642WA (en) 2016-04-28
MX2016003371A (es) 2016-10-21
EP3046901A1 (en) 2016-07-27
RU2016112257A (ru) 2017-10-20
BR112016005601A8 (pt) 2020-02-18
DK3046901T3 (en) 2018-01-02
KR101736416B1 (ko) 2017-05-16
CN105683152B (zh) 2017-03-22
EP3046901A4 (en) 2017-04-12
PL3046901T3 (pl) 2018-03-30
WO2015039173A1 (en) 2015-03-26
JP6122548B2 (ja) 2017-04-26
US20160221933A1 (en) 2016-08-04
JP2016532632A (ja) 2016-10-20
KR20160074471A (ko) 2016-06-28

Similar Documents

Publication Publication Date Title
CA2924356C (en) Compositions for the treatment of hypertension and/or fibrosis
TWI841532B (zh) 以稠合雙環吡唑治療代謝疾病之方法
JPWO2008139879A1 (ja) G蛋白質共役型レセプター抑制剤および医薬
CN102766103A (zh) 2-硫代-4-胺基-1-萘酚衍生物、其制备方法和用途
CN105085594A (zh) N6-(1-(4-甲氧基苯基)乙基)-腺苷的制备及用途
US20210346331A1 (en) Trpv4 activity inhibitor
JP4991537B2 (ja) シス−1,2−置換スチルベン誘導体、および糖尿病の治療および/または予防のための薬剤の製造におけるそれらの使用
CN106866652A (zh) 具有胰岛素增敏活性的小檗碱12‑位衍生物及其制备方法
JP5478082B2 (ja) インターロイキン−2産生抑制剤
KR102078433B1 (ko) 변비증의 예방 또는 치료약
HK1226324A1 (en) Compositions for the treatment of hypertension and/or fibrosis
HK1226324B (en) Compositions for the treatment of hypertension and/or fibrosis
RU2712624C9 (ru) Композиции для лечения заболевания почек и/или печени
JPH05503510A (ja) 光学的に純粋な(s)―アテノロールを含む組成物と方法
CN104447753B (zh) 一种西他列汀及其中间体的制备方法
CN103040807A (zh) 去-o-甲基毛狄泼老素在制备治疗高血压药物中的应用
CN107235842A (zh) 一种苯丙酸酯衍生物及其制备方法和应用
CN118530166A (zh) 氮杂二苯乙烯类化合物及在代谢综合征防治中的应用
Seedat Treatment of hypertension with the aid of beta-adrenergic blocking drugs
KR101051077B1 (ko) 2-피페라지노-4,5-이중치환-1,3-티아졸 유도체, 그의 제조방법 및 그를 유효성분으로 함유하는 spc 수용체 활성으로 유발되는 염증관련질환 치료제
CN115770238A (zh) 大麻素类化合物cbe的制备方法及其医药用途
JPWO2014030624A1 (ja) スチルベン誘導体を有効成分として含有する筋緊張性ジストロフィー治療剤
KR102036304B1 (ko) 신규한 브로모페놀 화합물 및 이를 유효성분으로 함유하는 비만 예방 또는 치료용 약학적 조성물
CN101829081A (zh) 色满类化合物hef-05用于舒张血管平滑肌的用途
JPH11222474A (ja) 糖尿病治療薬