AU2014324078B2 - Compositions for the treatment of hypertension and/or fibrosis - Google Patents

Compositions for the treatment of hypertension and/or fibrosis Download PDF

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Publication number
AU2014324078B2
AU2014324078B2 AU2014324078A AU2014324078A AU2014324078B2 AU 2014324078 B2 AU2014324078 B2 AU 2014324078B2 AU 2014324078 A AU2014324078 A AU 2014324078A AU 2014324078 A AU2014324078 A AU 2014324078A AU 2014324078 B2 AU2014324078 B2 AU 2014324078B2
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AU
Australia
Prior art keywords
fibrosis
compound
present
pharmaceutically acceptable
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2014324078A
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English (en)
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AU2014324078A1 (en
Inventor
Karen Annette Duggan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vectus Biosystems Ltd
Original Assignee
Vectus Biosystems Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2013903573A external-priority patent/AU2013903573A0/en
Application filed by Vectus Biosystems Ltd filed Critical Vectus Biosystems Ltd
Priority to AU2014324078A priority Critical patent/AU2014324078B2/en
Publication of AU2014324078A1 publication Critical patent/AU2014324078A1/en
Application granted granted Critical
Publication of AU2014324078B2 publication Critical patent/AU2014324078B2/en
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/09—Geometrical isomers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AU2014324078A 2013-09-17 2014-09-17 Compositions for the treatment of hypertension and/or fibrosis Active AU2014324078B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2014324078A AU2014324078B2 (en) 2013-09-17 2014-09-17 Compositions for the treatment of hypertension and/or fibrosis

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AU2013903573A AU2013903573A0 (en) 2013-09-17 Compositions for the treatment of hypertension and/or fibrosis
AU2013903573 2013-09-17
PCT/AU2014/000923 WO2015039173A1 (en) 2013-09-17 2014-09-17 Compositions for the treatment of hypertension and/or fibrosis
AU2014324078A AU2014324078B2 (en) 2013-09-17 2014-09-17 Compositions for the treatment of hypertension and/or fibrosis

Publications (2)

Publication Number Publication Date
AU2014324078A1 AU2014324078A1 (en) 2016-04-07
AU2014324078B2 true AU2014324078B2 (en) 2016-12-15

Family

ID=52687998

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2014324078A Active AU2014324078B2 (en) 2013-09-17 2014-09-17 Compositions for the treatment of hypertension and/or fibrosis

Country Status (22)

Country Link
US (1) US9458093B2 (enExample)
EP (1) EP3046901B1 (enExample)
JP (1) JP6122548B2 (enExample)
KR (1) KR101736416B1 (enExample)
CN (1) CN105683152B (enExample)
AP (1) AP2016009079A0 (enExample)
AU (1) AU2014324078B2 (enExample)
BR (1) BR112016005601B1 (enExample)
CA (1) CA2924356C (enExample)
DK (1) DK3046901T3 (enExample)
ES (1) ES2655455T3 (enExample)
IL (1) IL244621A (enExample)
MX (1) MX368865B (enExample)
MY (1) MY172557A (enExample)
NO (1) NO3046901T3 (enExample)
NZ (1) NZ717927A (enExample)
PH (1) PH12016500497B1 (enExample)
PL (1) PL3046901T3 (enExample)
RU (1) RU2635564C2 (enExample)
SG (1) SG11201601642WA (enExample)
UA (1) UA118111C2 (enExample)
WO (1) WO2015039173A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3284981B2 (ja) 1998-11-02 2002-05-27 株式会社デンソー 車両用交流発電機およびそのステータの製造方法
US9956166B2 (en) 2013-09-18 2018-05-01 Sorrento Therapeutics, Inc. Methods for administration and methods for treating cardiovascular diseases with resiniferatoxin
SG11201707561RA (en) * 2015-03-18 2017-10-30 Vectus Biosystems Ltd Compositions for the treatment of fibrosis and fibrosis-related conditions
NZ736165A (en) * 2015-03-18 2022-07-01 Vectus Biosystems Ltd Compositions for the treatment of kidney and/or liver disease
EP3353147B1 (en) * 2015-09-22 2021-01-13 Vectus Biosystems Limited Synthesis of terphenyl compounds
CN120114438A (zh) * 2016-04-13 2025-06-10 内布拉斯加大学董事会 施用树脂毒素的方法和用树脂毒素治疗心血管疾病的方法
BR112019001510B1 (pt) 2016-07-28 2022-11-08 Vectus Biosystems Limited Composto, e, uso de um composto para manufatura de um medicamento para tratar profilática ou terapeuticamente fibrose pulmonar, ou uma enfermidade relacionada em um indivíduo com fibrose pulmonar ou em risco de desenvolver fibrose pulmonar

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2694288B1 (fr) * 1992-06-30 1994-09-09 Rhone Poulenc Agrochimie Phenylbenzamides fongicides et procédés pour les préparer.
EP1768689B1 (en) * 2004-06-11 2014-08-20 Vectus Biosystems Limited Compositions and methods for treatment of cardiovascular disease
AU2006322656B2 (en) * 2005-12-09 2012-03-08 Vectus Biosystems Limited VIP fragments and methods of use
US20120088737A2 (en) * 2009-10-02 2012-04-12 Ajinomoto Co., Inc Novel acyl guanidine derivatives
US9630935B2 (en) * 2013-09-17 2017-04-25 Vectus Biosystems Limited Compositions for the treatment of hypertension and/or fibrosis

Also Published As

Publication number Publication date
PL3046901T3 (pl) 2018-03-30
RU2016112257A (ru) 2017-10-20
PH12016500497B1 (en) 2017-12-13
MX2016003371A (es) 2016-10-21
MY172557A (en) 2019-12-02
CA2924356C (en) 2018-04-03
UA118111C2 (uk) 2018-11-26
IL244621A0 (en) 2016-04-21
MX368865B (es) 2019-08-02
KR20160074471A (ko) 2016-06-28
KR101736416B1 (ko) 2017-05-16
SG11201601642WA (en) 2016-04-28
JP2016532632A (ja) 2016-10-20
AP2016009079A0 (en) 2016-03-31
ES2655455T3 (es) 2018-02-20
NZ717927A (en) 2018-12-21
BR112016005601A8 (pt) 2020-02-18
NO3046901T3 (enExample) 2018-03-17
DK3046901T3 (en) 2018-01-02
IL244621A (en) 2017-04-30
PH12016500497A1 (en) 2016-06-13
RU2635564C2 (ru) 2017-11-14
JP6122548B2 (ja) 2017-04-26
WO2015039173A1 (en) 2015-03-26
CN105683152B (zh) 2017-03-22
CN105683152A (zh) 2016-06-15
EP3046901A1 (en) 2016-07-27
CA2924356A1 (en) 2015-03-26
US20160221933A1 (en) 2016-08-04
EP3046901B1 (en) 2017-10-18
US9458093B2 (en) 2016-10-04
AU2014324078A1 (en) 2016-04-07
BR112016005601B1 (pt) 2021-02-02
EP3046901A4 (en) 2017-04-12

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