RU2603094C2 - Новый способ получения дифференцированных клеток - Google Patents

Новый способ получения дифференцированных клеток Download PDF

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RU2603094C2
RU2603094C2 RU2012114427/10A RU2012114427A RU2603094C2 RU 2603094 C2 RU2603094 C2 RU 2603094C2 RU 2012114427/10 A RU2012114427/10 A RU 2012114427/10A RU 2012114427 A RU2012114427 A RU 2012114427A RU 2603094 C2 RU2603094 C2 RU 2603094C2
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cells
gene
myc
genes
megakaryocytic
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RU2012114427A (ru
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Кои ЭТО
Наойя ТАКАЯМА
Соу НАКАМУРА
Хиромитсу НАКАУЧИ
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Зэ Юниверсити оф Токио
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    • C12N5/0634Cells from the blood or the immune system
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • C12N5/06Animal cells or tissues; Human cells or tissues
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    • C12N2506/45Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells

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RU2012114427/10A 2009-09-15 2010-09-15 Новый способ получения дифференцированных клеток RU2603094C2 (ru)

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JPJP2009-213645 2009-09-15
JP2009213645 2009-09-15
PCT/JP2010/065903 WO2011034073A1 (ja) 2009-09-15 2010-09-15 分化細胞の新規製造法

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RU2012114427A RU2012114427A (ru) 2013-10-27
RU2603094C2 true RU2603094C2 (ru) 2016-11-20

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US (2) US9200254B2 (enExample)
EP (2) EP3159001B1 (enExample)
JP (4) JP5791191B2 (enExample)
KR (2) KR101834687B1 (enExample)
CN (2) CN102712906B (enExample)
AU (1) AU2010296415B2 (enExample)
BR (2) BR112012005710B1 (enExample)
CA (1) CA2774193C (enExample)
DK (2) DK2500418T3 (enExample)
ES (2) ES2664194T3 (enExample)
IN (1) IN2012DN02642A (enExample)
RU (2) RU2603094C2 (enExample)
WO (1) WO2011034073A1 (enExample)

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JP5824760B2 (ja) * 2011-05-13 2015-12-02 国立大学法人 東京大学 多核化巨核球細胞、及び血小板の製造方法
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EP3973967A1 (en) 2012-12-21 2022-03-30 Astellas Institute for Regenerative Medicine Methods for production of platelets from pluripotent stem cells and compositions thereof
JP6495658B2 (ja) * 2013-02-08 2019-04-03 国立大学法人京都大学 巨核球及び血小板の製造方法
WO2014168255A1 (ja) * 2013-04-12 2014-10-16 国立大学法人京都大学 巨核球の成熟化促進物質
US20160060601A1 (en) 2013-04-17 2016-03-03 Nissan Chemical Industries, Ltd. Medium composition and method for producing red blood cells using same
US10260043B2 (en) * 2013-05-15 2019-04-16 University Of Rochester Human extensively self-renewing erythroblasts (ESRE)
WO2015199039A1 (ja) 2014-06-23 2015-12-30 東亞合成株式会社 細胞の多核化を誘導するペプチドおよびその利用
US20180044634A1 (en) 2015-03-09 2018-02-15 Megakaryon Corporation Method for Producing Culture Containing Megakaryocytes, and Method for Producing Platelets Using Same
RU2730034C2 (ru) * 2015-04-14 2020-08-14 Киото Юниверсити Способ получения клона стволовых клеток, пригодного для индуцирования дифференцировки в соматические клетки
KR20160129609A (ko) 2015-04-30 2016-11-09 삼성전자주식회사 Braf 저해제를 포함하는 세포 또는 개체의 노화를 감소시키기 위한 조성물 및 그의 용도
ES2833357T3 (es) * 2015-11-02 2021-06-15 Megakaryon Corp Procedimiento de preparación de plaquetas con un dispositivo de agitación recíproca
JP7350246B2 (ja) 2016-01-29 2023-09-26 国立大学法人京都大学 血小板産生促進剤のスクリーニング方法
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WO2018164040A1 (ja) 2017-03-06 2018-09-13 国立大学法人京都大学 血小板の製造方法
FR3068366B1 (fr) * 2017-06-30 2023-11-24 Francais Du Sang Ets Procede de production de progeniteurs erythroides
EP3650535A4 (en) 2017-07-07 2021-03-17 Kyoto University PROCESS AND APPARATUS FOR THE PRODUCTION OF PLATES AND METHOD FOR DETERMINING OPERATING CONDITIONS IN AN APPARATUS FOR THE PRODUCTION OF PLATES
WO2019059235A1 (ja) 2017-09-19 2019-03-28 株式会社メガカリオン 精製血小板の製造方法、血小板製剤の製造方法、血液製剤の製造方法、血小板保存液、血小板保存剤および血小板の保存方法
US12091683B2 (en) 2017-09-19 2024-09-17 Megakaryon Corporation Method for producing platelets, method for producing platelet product, and method for producing blood product
MX2020007071A (es) 2018-01-05 2020-11-11 Platelet Biogenesis Inc Composiciones y metodos para producir megacariocitos.
WO2020006539A1 (en) 2018-06-29 2020-01-02 Platelet Biogenesis, Inc. Compositions for drug delivery and methods of use thereof
US20200268839A1 (en) * 2019-02-25 2020-08-27 National Yang-Ming University Composition for treating pulmonary fibrosis and emphysema and therapeutic method using the same
US20220315895A1 (en) * 2019-05-01 2022-10-06 Transfusion Health, Llc Methods of making oligopotent and unipotent precursors
EP4074321A4 (en) 2019-12-12 2024-01-03 National University Corporation Chiba University Freeze-dried preparation containing megakaryocytes and platelets
US20230046238A1 (en) 2019-12-13 2023-02-16 Megakaryon Corporation Composition and use thereof
JPWO2022092169A1 (enExample) 2020-10-27 2022-05-05
JP7716851B2 (ja) * 2020-12-28 2025-08-01 イビデン株式会社 凍結保存液
EP4342982A4 (en) 2021-06-18 2025-05-28 Megakaryon Corporation Method for producing multinucleated megakaryocytes with increased platelet production capacity, platelet production method, and blood preparation production method
EP4365283A4 (en) 2021-06-30 2025-06-11 National University Corporation Chiba University Methods for improving the proliferative properties of common myeloid progenitor cells (CMP) or myelocytic progenitor cells
WO2024010317A1 (ko) * 2022-07-04 2024-01-11 주식회사 아트블러드 유전자 과발현 조합을 이용한 적혈구 분화능이 우수한 불멸화 적혈구전구세포주 확립, 이의 제조방법 및 용도
JP2025534107A (ja) 2022-10-18 2025-10-09 ソングァン メディカル ファンデーション 幹細胞から血小板前駆細胞への分化誘導用培地組成物及びそれを用いた分化方法
EP4644539A1 (en) 2022-12-28 2025-11-05 National University Corporation Chiba University Method for regulating degree of cell differentiation

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JP2017046719A (ja) 2017-03-09
CN102712906A (zh) 2012-10-03
EP2500418A1 (en) 2012-09-19
BR112012005710A2 (pt) 2017-11-21
US10087419B2 (en) 2018-10-02
CA2774193A1 (en) 2011-03-24
KR20160121592A (ko) 2016-10-19
RU2012114427A (ru) 2013-10-27
JP2015130866A (ja) 2015-07-23
DK3159001T3 (da) 2019-06-17
KR20120064109A (ko) 2012-06-18
JP2015213520A (ja) 2015-12-03
CN102712906B (zh) 2015-09-30
AU2010296415B2 (en) 2014-07-03
BR122013008030B8 (pt) 2021-07-27
BR112012005710B1 (pt) 2020-06-09
EP3159001A1 (en) 2017-04-26
KR101667834B1 (ko) 2016-10-20
US20160115449A1 (en) 2016-04-28
CN105385659A (zh) 2016-03-09
EP2500418A4 (en) 2013-04-10
JPWO2011034073A1 (ja) 2013-02-14
ES2664194T3 (es) 2018-04-18
EP3159001B1 (en) 2019-03-06
DK2500418T3 (en) 2018-04-30
CA2774193C (en) 2020-08-25
CN105385659B (zh) 2019-06-28
RU2661107C1 (ru) 2018-07-11
IN2012DN02642A (enExample) 2015-09-11
AU2010296415A1 (en) 2012-04-05
WO2011034073A1 (ja) 2011-03-24
BR122013008030A2 (pt) 2019-08-06
US9200254B2 (en) 2015-12-01
KR101834687B1 (ko) 2018-03-05
JP5791191B2 (ja) 2015-10-07
BR122013008030B1 (pt) 2021-01-05
EP2500418B1 (en) 2018-01-17
JP6382917B2 (ja) 2018-08-29
US20120238023A1 (en) 2012-09-20
JP6265437B2 (ja) 2018-01-24
ES2725688T3 (es) 2019-09-26

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