IN2012DN02642A - - Google Patents
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- Publication number
- IN2012DN02642A IN2012DN02642A IN2642DEN2012A IN2012DN02642A IN 2012DN02642 A IN2012DN02642 A IN 2012DN02642A IN 2642DEN2012 A IN2642DEN2012 A IN 2642DEN2012A IN 2012DN02642 A IN2012DN02642 A IN 2012DN02642A
- Authority
- IN
- India
- Prior art keywords
- cells
- oncogene
- differentiation stage
- present
- desired differentiation
- Prior art date
Links
- 230000004069 differentiation Effects 0.000 abstract 4
- 238000004519 manufacturing process Methods 0.000 abstract 3
- 108700020796 Oncogene Proteins 0.000 abstract 2
- 230000026969 oncogene-induced senescence Effects 0.000 abstract 2
- 230000024245 cell differentiation Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0641—Erythrocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/18—Erythrocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0644—Platelets; Megakaryocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/40—Regulators of development
- C12N2501/48—Regulators of apoptosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
- C12N2501/606—Transcription factors c-Myc
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Developmental Biology & Embryology (AREA)
- Diabetes (AREA)
- Virology (AREA)
- Oncology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009213645 | 2009-09-15 | ||
| PCT/JP2010/065903 WO2011034073A1 (ja) | 2009-09-15 | 2010-09-15 | 分化細胞の新規製造法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN02642A true IN2012DN02642A (enExample) | 2015-09-11 |
Family
ID=43758674
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN2642DEN2012 IN2012DN02642A (enExample) | 2009-09-15 | 2010-09-15 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US9200254B2 (enExample) |
| EP (2) | EP3159001B1 (enExample) |
| JP (4) | JP5791191B2 (enExample) |
| KR (2) | KR101834687B1 (enExample) |
| CN (2) | CN102712906B (enExample) |
| AU (1) | AU2010296415B2 (enExample) |
| BR (2) | BR122013008030B8 (enExample) |
| CA (1) | CA2774193C (enExample) |
| DK (2) | DK2500418T3 (enExample) |
| ES (2) | ES2725688T3 (enExample) |
| IN (1) | IN2012DN02642A (enExample) |
| RU (2) | RU2603094C2 (enExample) |
| WO (1) | WO2011034073A1 (enExample) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012043651A1 (ja) * | 2010-09-30 | 2012-04-05 | 国立大学法人 熊本大学 | ミエロイド系血液細胞の製造方法 |
| WO2012157586A1 (ja) * | 2011-05-13 | 2012-11-22 | 国立大学法人東京大学 | 多核化巨核球細胞、及び血小板の製造方法 |
| EP2765187B1 (en) | 2011-10-03 | 2018-08-08 | Nissan Chemical Industries, Ltd. | Method for producing megakaryocytes and/or platelets from pluripotent stem cells |
| GB201210857D0 (en) | 2012-06-19 | 2012-08-01 | Cambridge Entpr Ltd | Transcription factor mediated programming towards megakaryocytes |
| CN114558032B (zh) | 2012-12-21 | 2025-07-29 | 安斯泰来再生医药协会 | 由多能干细胞制备血小板的方法及其组合物 |
| US20160002599A1 (en) | 2013-02-08 | 2016-01-07 | Kyoto University | Production methods for megakaryocytes and platelets |
| JP6385340B2 (ja) * | 2013-04-12 | 2018-09-05 | 国立大学法人京都大学 | 巨核球の成熟化促進物質 |
| EP2987852A4 (en) | 2013-04-17 | 2016-09-07 | Nissan Chemical Ind Ltd | MEDIA COMPOSITION AND METHOD FOR THE PRODUCTION OF ERYTHROCYTES THEREWITH |
| CN111876387A (zh) * | 2013-05-15 | 2020-11-03 | 罗切斯特大学 | 人广泛自我更新型成红细胞(esre) |
| US10112977B2 (en) | 2014-06-23 | 2018-10-30 | Toagosei Co., Ltd. | Peptide for inducing multinucleation in cells, and use therefor |
| AU2016230059A1 (en) * | 2015-03-09 | 2017-09-28 | Kyoto University | Method for producing culture containing megakaryocytes, and method for producing platelets using same |
| CN107709543B (zh) * | 2015-04-14 | 2021-11-09 | 国立大学法人京都大学 | 制造适于向体细胞分化诱导的干细胞克隆的方法 |
| KR20160129609A (ko) | 2015-04-30 | 2016-11-09 | 삼성전자주식회사 | Ｂｒａｆ 저해제를 포함하는 세포 또는 개체의 노화를 감소시키기 위한 조성물 및 그의 용도 |
| DK3372674T3 (da) * | 2015-11-02 | 2020-10-12 | Megakaryon Corp | Fremgangsmåde til fremstilling af blodplader under anvendelse af røreindretning med frem- og tilbagegående rørebevægelse |
| EP3453759B1 (en) | 2016-01-29 | 2023-08-30 | Kyoto University | Platelet production promoter and method of producing platelets using same |
| EP3409774B1 (en) | 2016-01-29 | 2025-03-19 | Kyoto University | Screening method of platelet production promoter |
| WO2018164040A1 (ja) | 2017-03-06 | 2018-09-13 | 国立大学法人京都大学 | 血小板の製造方法 |
| FR3068366B1 (fr) * | 2017-06-30 | 2023-11-24 | Francais Du Sang Ets | Procede de production de progeniteurs erythroides |
| US12600948B2 (en) | 2017-07-07 | 2026-04-14 | Kyoto University | Method and apparatus for producing platelet and method for determining operating condition of apparatus for producing platelet |
| JP7323126B2 (ja) | 2017-09-19 | 2023-08-08 | 株式会社メガカリオン | 精製血小板の製造方法、血小板製剤の製造方法、血液製剤の製造方法、血小板保存液、血小板保存剤および血小板の保存方法 |
| US12091683B2 (en) | 2017-09-19 | 2024-09-17 | Megakaryon Corporation | Method for producing platelets, method for producing platelet product, and method for producing blood product |
| MX2020007071A (es) * | 2018-01-05 | 2020-11-11 | Platelet Biogenesis Inc | Composiciones y metodos para producir megacariocitos. |
| EP3813853A4 (en) | 2018-06-29 | 2022-04-06 | Platelet Biogenesis, Inc. | DELIVERY COMPOSITIONS AND METHODS OF USE |
| TW202045202A (zh) * | 2019-02-25 | 2020-12-16 | 國立陽明大學 | 用於治療肺纖維化和肺氣腫的組合物及其使用方法 |
| AU2020265737A1 (en) * | 2019-05-01 | 2021-12-02 | Immunebridge Inc. | Methods of making oligopotent and unipotent precursors |
| US20230030814A1 (en) | 2019-12-12 | 2023-02-02 | National University Corporation Chiba University | Freeze-Dried Preparations Comprising Megakaryocytes and Platelets |
| JP7850558B2 (ja) | 2019-12-13 | 2026-04-23 | 株式会社メガカリオン | 組成物およびその用途 |
| US20230399617A1 (en) | 2020-10-27 | 2023-12-14 | Nagasaki University | Osteogenic composition and use thereof |
| JP7716851B2 (ja) * | 2020-12-28 | 2025-08-01 | イビデン株式会社 | 凍結保存液 |
| KR20240019327A (ko) | 2021-06-18 | 2024-02-14 | 가부시키가이샤 메가카리온 | 혈소판 산생능이 증강된 다핵화 거핵구 세포의 제조 방법, 혈소판의 제조 방법, 혈소판 제제의 제조 방법 및 혈액 제제의 제조 방법 |
| US20240301353A1 (en) | 2021-06-30 | 2024-09-12 | National University Corporation Chiba University | Method for improving proliferative properties of common myeloid progenitor cells (cmp) or myelocytic progenitor cells |
| US20250346860A1 (en) * | 2022-07-04 | 2025-11-13 | Artblood Inc. | Establishment of immortalized erythroid progenitor cell line with superior capability of differentiating into red blood cells by using genetic overexpression combination, preparation method therefor, and use thereof |
| WO2024085650A1 (ko) | 2022-10-18 | 2024-04-25 | 의료법인 성광의료재단 | 줄기세포에서 혈소판 전구세포로의 분화 유도용 배지 조성물 및 이를 이용한 분화 방법 |
| KR20250142323A (ko) | 2022-12-28 | 2025-09-30 | 고쿠리츠 다이가쿠 호우징 지바 다이가쿠 | 세포분화도의 조절 방법 |
| CN121219404A (zh) | 2023-04-03 | 2025-12-26 | 大塚制药株式会社 | 巨核细胞的制造方法 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US572333A (en) | 1896-12-01 | Evaporating apparatus | ||
| CA2112492A1 (en) | 1991-06-28 | 1993-01-07 | Hava Avraham | A differentiated megakaryocyte line producing novel megakaryocyte differentiation factors |
| GB9502022D0 (en) * | 1995-02-02 | 1995-03-22 | Abuljadayel Ilham M S | A method for preparing lymphohaematopoietic progenitor cells |
| US5723333A (en) | 1995-02-10 | 1998-03-03 | Regents Of The University Of California | Human pancreatic cell lines: developments and uses |
| CA2210685A1 (en) | 1995-02-10 | 1996-08-15 | The Regents Of The University Of California | Human pancreatic cell lines: developments and uses |
| US20050159378A1 (en) * | 2001-05-18 | 2005-07-21 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of Myc and/or Myb gene expression using short interfering nucleic acid (siNA) |
| JP4344696B2 (ja) * | 2002-09-27 | 2009-10-14 | バイオイー， インコーポレイテッド | 細胞分離組成物および細胞分離法 |
| JP3896482B2 (ja) * | 2002-10-07 | 2007-03-22 | 独立行政法人産業技術総合研究所 | 分化細胞の作製方法 |
| JP2004350601A (ja) | 2003-05-29 | 2004-12-16 | Tanabe Seiyaku Co Ltd | 霊長類動物の胚性幹細胞から造血系細胞への分化方法 |
| JP4706208B2 (ja) | 2004-08-27 | 2011-06-22 | 株式会社アイル | 造血幹細胞の製造方法 |
| JP2006141356A (ja) | 2004-11-24 | 2006-06-08 | Institute Of Physical & Chemical Research | Ｅｓ細胞から樹立された造血幹細胞 |
| IN2014DN06624A (enExample) * | 2005-10-18 | 2015-07-10 | Univ Colorado | |
| US20090220465A1 (en) * | 2005-11-07 | 2009-09-03 | The General Hospital Corporation | Methods and compositions for modulation of stem cell aging |
| CN101864392B (zh) * | 2005-12-13 | 2016-03-23 | 国立大学法人京都大学 | 核重新编程因子 |
| US8058064B2 (en) * | 2006-10-04 | 2011-11-15 | The University Of Tokyo | Sac-like structure enclosing hematopoietic progenitor cells produced from ES cells and method for preparing blood cells |
| AU2008297024B2 (en) * | 2007-10-31 | 2014-08-28 | Kyoto University | Nuclear reprogramming method |
| CN101492676B (zh) * | 2008-09-16 | 2011-02-16 | 中国科学院广州生物医药与健康研究院 | 用脑膜细胞生成诱导的多能性干细胞的方法及其用途 |
-
2010
- 2010-09-15 RU RU2012114427/10A patent/RU2603094C2/ru active
- 2010-09-15 CN CN201080042161.7A patent/CN102712906B/zh active Active
- 2010-09-15 CA CA2774193A patent/CA2774193C/en active Active
- 2010-09-15 EP EP16202612.4A patent/EP3159001B1/en active Active
- 2010-09-15 ES ES16202612T patent/ES2725688T3/es active Active
- 2010-09-15 DK DK10817186.9T patent/DK2500418T3/en active
- 2010-09-15 KR KR1020167027550A patent/KR101834687B1/ko active Active
- 2010-09-15 BR BR122013008030A patent/BR122013008030B8/pt active IP Right Grant
- 2010-09-15 DK DK16202612.4T patent/DK3159001T3/da active
- 2010-09-15 CN CN201510530896.9A patent/CN105385659B/zh not_active Expired - Fee Related
- 2010-09-15 WO PCT/JP2010/065903 patent/WO2011034073A1/ja not_active Ceased
- 2010-09-15 IN IN2642DEN2012 patent/IN2012DN02642A/en unknown
- 2010-09-15 US US13/496,321 patent/US9200254B2/en active Active
- 2010-09-15 JP JP2011531940A patent/JP5791191B2/ja active Active
- 2010-09-15 RU RU2016139042A patent/RU2661107C1/ru active
- 2010-09-15 EP EP10817186.9A patent/EP2500418B1/en active Active
- 2010-09-15 ES ES10817186.9T patent/ES2664194T3/es active Active
- 2010-09-15 AU AU2010296415A patent/AU2010296415B2/en active Active
- 2010-09-15 KR KR1020127009225A patent/KR101667834B1/ko active Active
- 2010-09-15 BR BR112012005710A patent/BR112012005710B1/pt active IP Right Grant
-
2015
- 2015-02-13 JP JP2015026547A patent/JP2015130866A/ja active Pending
- 2015-08-03 JP JP2015153048A patent/JP6265437B2/ja active Active
- 2015-10-28 US US14/925,508 patent/US10087419B2/en active Active
-
2016
- 2016-11-29 JP JP2016231020A patent/JP6382917B2/ja active Active
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