DK3372674T3 - Fremgangsmåde til fremstilling af blodplader under anvendelse af røreindretning med frem- og tilbagegående rørebevægelse - Google Patents
Fremgangsmåde til fremstilling af blodplader under anvendelse af røreindretning med frem- og tilbagegående rørebevægelse Download PDFInfo
- Publication number
- DK3372674T3 DK3372674T3 DK16862024.3T DK16862024T DK3372674T3 DK 3372674 T3 DK3372674 T3 DK 3372674T3 DK 16862024 T DK16862024 T DK 16862024T DK 3372674 T3 DK3372674 T3 DK 3372674T3
- Authority
- DK
- Denmark
- Prior art keywords
- agitator
- motion
- reciprocating
- making platelets
- platelets
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/02—Stirrer or mobile mixing elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/19—Platelets; Megacaryocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
- A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
- B01F27/05—Stirrers
- B01F27/11—Stirrers characterised by the configuration of the stirrers
- B01F27/112—Stirrers characterised by the configuration of the stirrers with arms, paddles, vanes or blades
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
- B01F27/80—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis
- B01F27/91—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis with propellers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
- C12M1/02—Apparatus for enzymology or microbiology with agitation means; with heat exchange means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M21/00—Bioreactors or fermenters specially adapted for specific uses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus
- C12M3/08—Apparatus for tissue disaggregation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/48—Automatic or computerized control
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0644—Platelets; Megakaryocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
- C12N2015/8527—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic for producing animal models, e.g. for tests or diseases
- C12N2015/8572—Animal models for proliferative diseases, e.g. comprising an oncogene
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
- C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/38—Vitamins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/125—Stem cell factor [SCF], c-kit ligand [KL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/145—Thrombopoietin [TPO]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/165—Vascular endothelial growth factor [VEGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/72—Transferases (EC 2.)
- C12N2501/727—Kinases (EC 2.7.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/70—Enzymes
- C12N2501/73—Hydrolases (EC 3.)
- C12N2501/734—Proteases (EC 3.4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/45—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from artificially induced pluripotent stem cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/04—Immortalised cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2527/00—Culture process characterised by the use of mechanical forces, e.g. strain, vibration
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2015215936 | 2015-11-02 | ||
PCT/JP2016/082206 WO2017077964A1 (ja) | 2015-11-02 | 2016-10-31 | 往復動撹拌装置を用いた血小板の製造方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3372674T3 true DK3372674T3 (da) | 2020-10-12 |
Family
ID=58663012
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK16862024.3T DK3372674T3 (da) | 2015-11-02 | 2016-10-31 | Fremgangsmåde til fremstilling af blodplader under anvendelse af røreindretning med frem- og tilbagegående rørebevægelse |
Country Status (11)
Country | Link |
---|---|
US (1) | US20180318352A1 (da) |
EP (1) | EP3372674B1 (da) |
JP (1) | JP6856537B2 (da) |
CN (1) | CN108473954A (da) |
AU (1) | AU2016350296B2 (da) |
CA (1) | CA3003679A1 (da) |
DK (1) | DK3372674T3 (da) |
ES (1) | ES2833357T3 (da) |
RU (1) | RU2741871C2 (da) |
SG (1) | SG11201803591UA (da) |
WO (1) | WO2017077964A1 (da) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11952587B2 (en) | 2017-03-06 | 2024-04-09 | Kyoto University | Method for producing platelets |
WO2019009364A1 (ja) | 2017-07-07 | 2019-01-10 | 国立大学法人京都大学 | 血小板の製造方法および製造装置、ならびに血小板の製造装置における運転条件の決定方法 |
US11773374B2 (en) | 2017-09-19 | 2023-10-03 | Megakaryon Corporation | Method for producing purified platelets, method for producing platelet product, method for producing blood product, platelet preserving solution, platelet preserving agent, and method for preserving platelets |
JP6423942B1 (ja) * | 2017-11-08 | 2018-11-14 | 佐竹化学機械工業株式会社 | マイクロキャリア撹拌培養装置 |
JP7280679B2 (ja) * | 2018-10-04 | 2023-05-24 | 佐竹マルチミクス株式会社 | 撹拌培養装置 |
CN109592777B (zh) * | 2018-12-28 | 2022-08-09 | 杭州汉山环境工程技术有限公司 | 一种污水氧化处理设备 |
CN109967016B (zh) * | 2019-01-23 | 2021-03-19 | 南京市江宁医院 | 一种流体运动模式体外人工合成血小板方法 |
EP3940061A4 (en) | 2019-03-15 | 2023-01-04 | Megakaryon Corporation | PRESERVATION LIQUID FOR MAMMALIAN CELLS |
EP4043097A4 (en) | 2019-09-27 | 2023-11-01 | Shoji Katsume | AGITATION BODY AND AGITATION DEVICE INCLUDING SAME |
CN112089897B (zh) * | 2020-07-30 | 2023-09-15 | 京美德(深圳)医疗科技有限公司 | 一种介入式给药引流治疗装置 |
FR3122185A1 (fr) * | 2021-04-21 | 2022-10-28 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Procede de liberation de plaquettes en regime turbulent et systeme de liberation de plaquettes pour la mise en œuvre de ce procede |
CN114480121B (zh) * | 2022-01-13 | 2022-12-09 | 山东水发生命科学研究有限公司 | 适用于细胞生长的反应装置 |
WO2023153401A1 (ja) * | 2022-02-10 | 2023-08-17 | 佐竹マルチミクス株式会社 | 血小板を製造するための撹拌装置、及び該撹拌装置の制御方法 |
JP7376897B2 (ja) | 2022-03-09 | 2023-11-09 | 成浩 小島 | 摘出組織処理装置、および摘出組織処理方法 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2068265C1 (ru) * | 1992-11-27 | 1996-10-27 | Валентин Анатольевич Лифановский | Способ получения тромбоцитов |
US6491422B1 (en) * | 2000-05-16 | 2002-12-10 | Rütten Engineering | Mixer |
US20050249033A1 (en) * | 2004-05-04 | 2005-11-10 | Krause Richard J | Disposable reciprocating bag mixing systems |
DE102006020461B3 (de) * | 2006-04-28 | 2007-10-04 | Sartorius Biotech Gmbh | Behälter mit flexiblen Wänden |
ATE481162T1 (de) * | 2007-11-01 | 2010-10-15 | Mettler Toledo Ag | Rührereinheit aufweisend einen adapter |
JP5617631B2 (ja) * | 2008-04-01 | 2014-11-05 | 国立大学法人東京大学 | iPS細胞からの血小板の調製方法 |
JP5419076B2 (ja) * | 2008-05-15 | 2014-02-19 | 旭化成メディカル株式会社 | 血小板の誘導方法 |
DE102008025507A1 (de) * | 2008-05-28 | 2009-12-03 | Sartorius Stedim Biotech Gmbh | Mischsystem |
AU2009280612B2 (en) * | 2008-08-11 | 2014-11-13 | Fujimori Kogyo Co., Ltd. | Blood-platelet test method and blood-platelet test device |
JP5863459B2 (ja) * | 2008-12-04 | 2016-02-16 | インセルム (アンスティテュ・ナショナル・ドゥ・ラ・サント・エ・ドゥ・ラ・ルシェルシュ・メディカル)INSERM (Institut National de la Sante et de la Recherche Medicale) | 血小板の産生方法 |
AU2012256880B2 (en) * | 2011-05-13 | 2015-09-17 | The University Of Tokyo | Method for producing polyploidized megakaryocyte and platelets |
CA2896053A1 (en) * | 2012-12-21 | 2014-06-26 | Ocata Therapeutics, Inc. | Methods for production of platelets from pluripotent stem cells and compositions thereof |
WO2014123242A1 (ja) * | 2013-02-08 | 2014-08-14 | 国立大学法人京都大学 | 巨核球及び血小板の製造方法 |
AU2014352015B2 (en) * | 2013-11-19 | 2019-10-03 | Espci Paristech | Fluidic device for producing platelets |
JP2015181405A (ja) * | 2014-03-24 | 2015-10-22 | 東レエンジニアリング株式会社 | 血小板産生装置および血小板産生方法 |
JP6467735B2 (ja) * | 2014-07-18 | 2019-02-13 | 佐竹化学機械工業株式会社 | 培地抜出機能を有した往復動撹拌培養装置 |
US10092888B2 (en) * | 2014-11-07 | 2018-10-09 | Genesis Technologies, Llc | Linear reciprocating actuator |
EP3271450B1 (en) * | 2015-03-19 | 2019-11-06 | Labruzzo, Pietro | Method and bioreactor for producing a culture of microorganisms |
-
2016
- 2016-10-31 US US15/773,099 patent/US20180318352A1/en active Pending
- 2016-10-31 JP JP2017548743A patent/JP6856537B2/ja active Active
- 2016-10-31 WO PCT/JP2016/082206 patent/WO2017077964A1/ja active Application Filing
- 2016-10-31 CN CN201680063249.4A patent/CN108473954A/zh active Pending
- 2016-10-31 ES ES16862024T patent/ES2833357T3/es active Active
- 2016-10-31 SG SG11201803591UA patent/SG11201803591UA/en unknown
- 2016-10-31 RU RU2018120143A patent/RU2741871C2/ru active
- 2016-10-31 EP EP16862024.3A patent/EP3372674B1/en active Active
- 2016-10-31 CA CA3003679A patent/CA3003679A1/en not_active Abandoned
- 2016-10-31 DK DK16862024.3T patent/DK3372674T3/da active
- 2016-10-31 AU AU2016350296A patent/AU2016350296B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
RU2018120143A (ru) | 2019-12-04 |
RU2018120143A3 (da) | 2020-04-06 |
JP6856537B2 (ja) | 2021-04-07 |
AU2016350296A1 (en) | 2018-05-31 |
AU2016350296B2 (en) | 2022-02-10 |
ES2833357T3 (es) | 2021-06-15 |
CA3003679A1 (en) | 2017-05-11 |
WO2017077964A1 (ja) | 2017-05-11 |
KR20180080261A (ko) | 2018-07-11 |
EP3372674A1 (en) | 2018-09-12 |
US20180318352A1 (en) | 2018-11-08 |
RU2741871C2 (ru) | 2021-01-29 |
CN108473954A (zh) | 2018-08-31 |
EP3372674B1 (en) | 2020-10-07 |
EP3372674A4 (en) | 2019-04-24 |
JPWO2017077964A1 (ja) | 2018-10-11 |
SG11201803591UA (en) | 2018-05-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK3372674T3 (da) | Fremgangsmåde til fremstilling af blodplader under anvendelse af røreindretning med frem- og tilbagegående rørebevægelse | |
CL2018000370A1 (es) | Nuevos anticuerpos anti-pd-1 | |
DK3344654T3 (da) | Anti-lag-3-antistoffer | |
DK3332006T3 (da) | Hidtil ukendte anti-PD-L1-antistoffer | |
DK3183272T3 (da) | Asymmetriske multispecifikke antistoffer | |
DK3294700T3 (da) | Fremgangsmåde til fremstilling af limonen-4-ol | |
DK3122444T3 (da) | Fremgangsmåde til fremstilling af membraner | |
DK3350218T3 (da) | Polyomavirus-neutraliserende antistoffer | |
DK3341479T3 (da) | LNA-G-Proces | |
DK3250593T3 (da) | Anti-transthyretin-antistoffer | |
DK3270748T3 (da) | Maskine til tilberedning af drikke med gentagelig karakteristik | |
DK3253453T3 (da) | Fremgangsmåde til fremstilling af mælk med højt indbygget vitamin D3-indhold | |
DK3191498T3 (da) | Fremgangsmåde til fremstilling af 2'-o-fucosyllactose | |
DK3218396T3 (da) | Fremgangsmåde til fremstilling af højaffinitets antistoffer | |
DK3307436T3 (da) | Mikrofluidanordning | |
DK3265439T3 (da) | Fremgangsmåde til fremstilling af 3-chlor-2-vinylphenylsulfonater | |
DK3137449T3 (da) | Fremgangsmåder til fremstilling af substituerede cycloseriner | |
DK3430072T3 (da) | Fremgangsmåde til oprensning af poloxamerer | |
UY4467S (es) | Frasco | |
DK3174402T3 (da) | Fremgangsmåde til fremstilling af mælkepulver | |
DK3131567T3 (da) | Fremgangsmåde til fremstilling af GNRH-holdig gel | |
DK3313453T3 (da) | Metode til billeddannelse af gigt | |
DK3356541T3 (da) | Fremgangsmåde til fremstilling af l-methionin | |
DK3280699T3 (da) | Fremgangsmåde til fremstilling af acylsulfamoylbenzamider | |
DK3154942T3 (da) | Fremstilling af piperidin-4-carbothioamid |