CA2774193C - Novel method for producing differentiated cells - Google Patents
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- CA2774193C CA2774193C CA2774193A CA2774193A CA2774193C CA 2774193 C CA2774193 C CA 2774193C CA 2774193 A CA2774193 A CA 2774193A CA 2774193 A CA2774193 A CA 2774193A CA 2774193 C CA2774193 C CA 2774193C
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| CN103814126B (zh) * | 2011-05-13 | 2017-10-24 | 国立大学法人东京大学 | 多核巨核细胞以及血小板的制造方法 |
| JP5876498B2 (ja) * | 2011-10-03 | 2016-03-02 | 日産化学工業株式会社 | 多能性幹細胞からの巨核球及び／又は血小板の製造方法 |
| GB201210857D0 (en) | 2012-06-19 | 2012-08-01 | Cambridge Entpr Ltd | Transcription factor mediated programming towards megakaryocytes |
| CN105101979B (zh) | 2012-12-21 | 2021-10-08 | 安斯泰来再生医药协会 | 由多能干细胞制备血小板的方法及其组合物 |
| JP6495658B2 (ja) * | 2013-02-08 | 2019-04-03 | 国立大学法人京都大学 | 巨核球及び血小板の製造方法 |
| JP6385340B2 (ja) * | 2013-04-12 | 2018-09-05 | 国立大学法人京都大学 | 巨核球の成熟化促進物質 |
| EP2987852A4 (en) | 2013-04-17 | 2016-09-07 | Nissan Chemical Ind Ltd | MEDIA COMPOSITION AND METHOD FOR THE PRODUCTION OF ERYTHROCYTES THEREWITH |
| CN111876387A (zh) * | 2013-05-15 | 2020-11-03 | 罗切斯特大学 | 人广泛自我更新型成红细胞(esre) |
| US10112977B2 (en) | 2014-06-23 | 2018-10-30 | Toagosei Co., Ltd. | Peptide for inducing multinucleation in cells, and use therefor |
| US20180044634A1 (en) * | 2015-03-09 | 2018-02-15 | Megakaryon Corporation | Method for Producing Culture Containing Megakaryocytes, and Method for Producing Platelets Using Same |
| EP3296390B1 (en) * | 2015-04-14 | 2023-01-04 | Kyoto University | Method for producing stem cell clones suitable for induction of differentiation into somatic cells |
| KR20160129609A (ko) | 2015-04-30 | 2016-11-09 | 삼성전자주식회사 | Ｂｒａｆ 저해제를 포함하는 세포 또는 개체의 노화를 감소시키기 위한 조성물 및 그의 용도 |
| DK3372674T3 (da) * | 2015-11-02 | 2020-10-12 | Megakaryon Corp | Fremgangsmåde til fremstilling af blodplader under anvendelse af røreindretning med frem- og tilbagegående rørebevægelse |
| EP3453759B1 (en) | 2016-01-29 | 2023-08-30 | Kyoto University | Platelet production promoter and method of producing platelets using same |
| JP7350246B2 (ja) | 2016-01-29 | 2023-09-26 | 国立大学法人京都大学 | 血小板産生促進剤のスクリーニング方法 |
| JP7297203B2 (ja) | 2017-03-06 | 2023-06-26 | 国立大学法人京都大学 | 血小板の製造方法 |
| FR3068366B1 (fr) * | 2017-06-30 | 2023-11-24 | Francais Du Sang Ets | Procede de production de progeniteurs erythroides |
| WO2019009364A1 (ja) | 2017-07-07 | 2019-01-10 | 国立大学法人京都大学 | 血小板の製造方法および製造装置、ならびに血小板の製造装置における運転条件の決定方法 |
| JP7160353B2 (ja) | 2017-09-19 | 2022-10-25 | 株式会社メガカリオン | 血小板の製造方法、血小板製剤の製造方法、および血液製剤の製造方法 |
| US11773374B2 (en) | 2017-09-19 | 2023-10-03 | Megakaryon Corporation | Method for producing purified platelets, method for producing platelet product, method for producing blood product, platelet preserving solution, platelet preserving agent, and method for preserving platelets |
| KR102592176B1 (ko) | 2018-01-05 | 2023-10-20 | 플레이틀렛 바이오제네시스, 인크. | 거핵구 생성을 위한 조성물 및 방법 |
| WO2020006539A1 (en) | 2018-06-29 | 2020-01-02 | Platelet Biogenesis, Inc. | Compositions for drug delivery and methods of use thereof |
| TW202045202A (zh) * | 2019-02-25 | 2020-12-16 | 國立陽明大學 | 用於治療肺纖維化和肺氣腫的組合物及其使用方法 |
| WO2020223517A1 (en) * | 2019-05-01 | 2020-11-05 | Transfusion Health, Llc | Methods of making oligopotent and unipotent precursors |
| US20230030814A1 (en) | 2019-12-12 | 2023-02-02 | National University Corporation Chiba University | Freeze-Dried Preparations Comprising Megakaryocytes and Platelets |
| EP4063489A4 (en) | 2019-12-13 | 2024-02-28 | Megakaryon Corporation | COMPOSITION AND USE THEREOF |
| CN116437940A (zh) | 2020-10-27 | 2023-07-14 | 国立大学法人长崎大学 | 骨形成组合物和其用途 |
| JP7716851B2 (ja) * | 2020-12-28 | 2025-08-01 | イビデン株式会社 | 凍結保存液 |
| CN117500913A (zh) | 2021-06-18 | 2024-02-02 | 株式会社美加细胞 | 血小板产生能力得到增强的多核化巨核细胞的制造方法、血小板的制造方法、血小板制剂的制造方法及血液制剂的制造方法 |
| WO2023277153A1 (ja) | 2021-06-30 | 2023-01-05 | 国立大学法人千葉大学 | 骨髄系共通前駆細胞（ｃｍｐ）又は骨髄球系前駆細胞の増殖性を向上させる方法 |
| WO2024010317A1 (ko) * | 2022-07-04 | 2024-01-11 | 주식회사 아트블러드 | 유전자 과발현 조합을 이용한 적혈구 분화능이 우수한 불멸화 적혈구전구세포주 확립, 이의 제조방법 및 용도 |
| JP2025534107A (ja) | 2022-10-18 | 2025-10-09 | ソングァン メディカル ファンデーション | 幹細胞から血小板前駆細胞への分化誘導用培地組成物及びそれを用いた分化方法 |
| AU2023415203A1 (en) | 2022-12-28 | 2025-08-07 | National University Corporation Chiba University | Method for regulating degree of cell differentiation |
| TW202444899A (zh) | 2023-04-03 | 2024-11-16 | 日商大塚製藥股份有限公司 | 巨核細胞之製造方法 |
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| CA2112492A1 (en) * | 1991-06-28 | 1993-01-07 | Hava Avraham | A differentiated megakaryocyte line producing novel megakaryocyte differentiation factors |
| GB9502022D0 (en) * | 1995-02-02 | 1995-03-22 | Abuljadayel Ilham M S | A method for preparing lymphohaematopoietic progenitor cells |
| US5723333A (en) | 1995-02-10 | 1998-03-03 | Regents Of The University Of California | Human pancreatic cell lines: developments and uses |
| JPH10513358A (ja) * | 1995-02-10 | 1998-12-22 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | ヒト膵臓細胞系：発達と用途 |
| US20050159378A1 (en) * | 2001-05-18 | 2005-07-21 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of Myc and/or Myb gene expression using short interfering nucleic acid (siNA) |
| CA2499826C (en) * | 2002-09-27 | 2015-03-24 | Bioe, Inc. | Cell separation compositions and methods |
| JP3896482B2 (ja) * | 2002-10-07 | 2007-03-22 | 独立行政法人産業技術総合研究所 | 分化細胞の作製方法 |
| JP2004350601A (ja) | 2003-05-29 | 2004-12-16 | Tanabe Seiyaku Co Ltd | 霊長類動物の胚性幹細胞から造血系細胞への分化方法 |
| JP4706208B2 (ja) | 2004-08-27 | 2011-06-22 | 株式会社アイル | 造血幹細胞の製造方法 |
| JP2006141356A (ja) | 2004-11-24 | 2006-06-08 | Institute Of Physical & Chemical Research | Ｅｓ細胞から樹立された造血幹細胞 |
| JP2009511081A (ja) | 2005-10-18 | 2009-03-19 | ナショナル ジューイッシュ メディカル アンド リサーチ センター | 条件的に不死化された長期幹細胞およびそのような細胞を作製および使用する方法 |
| AU2006311637A1 (en) * | 2005-11-07 | 2007-05-18 | The General Hospital Corporation | Methods and compositions for modulation of stem cell aging |
| EP4223769A3 (en) * | 2005-12-13 | 2023-11-01 | Kyoto University | Nuclear reprogramming factor |
| US8058064B2 (en) | 2006-10-04 | 2011-11-15 | The University Of Tokyo | Sac-like structure enclosing hematopoietic progenitor cells produced from ES cells and method for preparing blood cells |
| AU2008297024B2 (en) * | 2007-10-31 | 2014-08-28 | Kyoto University | Nuclear reprogramming method |
| CN101492676B (zh) * | 2008-09-16 | 2011-02-16 | 中国科学院广州生物医药与健康研究院 | 用脑膜细胞生成诱导的多能性干细胞的方法及其用途 |
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