RU2555526C2 - Антитела, связывающиеся с протофибриллами, и их применение в методах терапии и диагностики болезни паркинсона, деменции, ассоциированной с образованием диффузных телец леви, и других альфа-синуклеинопатий - Google Patents
Антитела, связывающиеся с протофибриллами, и их применение в методах терапии и диагностики болезни паркинсона, деменции, ассоциированной с образованием диффузных телец леви, и других альфа-синуклеинопатий Download PDFInfo
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Cited By (2)
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| RU2760334C2 (ru) * | 2016-12-22 | 2021-11-24 | Х. Лундбекк А/С | Моноклональные антитела к альфа-синуклеину для предотвращения агрегации тау-белка |
| RU2787039C2 (ru) * | 2017-12-15 | 2022-12-28 | Юсб Биофарма Срл | Антитела против альфа-синуклеина |
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| US10989718B2 (en) * | 2014-09-11 | 2021-04-27 | Amprion, Inc. | Detection of misfolded alpha synuclein protein |
| PT2663579T (pt) | 2011-01-14 | 2017-07-28 | Univ California | Terapêutica de anticorpos contra a proteína r0r-1 e métodos para sua utilização |
| KR20200014441A (ko) * | 2012-01-20 | 2020-02-10 | 젠자임 코포레이션 | 항cxcr3 항체 |
| US9534044B2 (en) * | 2013-02-28 | 2017-01-03 | United Arab Emirates University | Alpha-synuclein antibodies and uses thereof |
| CA2924268C (en) | 2013-11-21 | 2021-05-18 | F. Hoffmann-La Roche Ag | Anti-alpha-synuclein antibodies and methods of use |
| JO3537B1 (ar) * | 2014-07-10 | 2020-07-05 | Bioarctic Neuroscience Ab | أجسام مضادة لييفية أولية لاميلويد بيتا الببتيد ab المحسنة |
| EP3207057A2 (en) | 2014-10-16 | 2017-08-23 | F. Hoffmann-La Roche AG | Anti-alpha-synuclein antibodies and methods of use |
| US10494425B2 (en) * | 2015-02-24 | 2019-12-03 | Rpeptide, Llc | Anti-amyloid-beta antibodies |
| EP3091087A1 (en) | 2015-05-08 | 2016-11-09 | Fundació Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol | Method for in vitro diagnosis of synucleinopathies using alpha-synuclein gene transcripts |
| GB201512203D0 (en) | 2015-07-13 | 2015-08-19 | Lundbeck & Co As H | Agents,uses and methods |
| US11327080B2 (en) | 2015-07-21 | 2022-05-10 | BioArctic Neruoscience AB | Method for treatment of traumatic brain injury targeting aggregated peptides |
| CA3004498A1 (en) | 2015-11-09 | 2017-05-18 | Neil R. Cashman | Amyloid beta epitopes and antibodies thereto |
| EP3374379A4 (en) | 2015-11-09 | 2019-05-15 | The University Of British Columbia | N-TERMINAL EPITOPES IN AMYLOID BETA AND CONFORMATION-SELECTIVE ANTIBODIES |
| JP7448174B2 (ja) | 2015-11-09 | 2024-03-12 | ザ・ユニバーシティ・オブ・ブリティッシュ・コロンビア | アミロイドベータ中間領域エピトープおよびそれに対する立体配座選択的抗体 |
| AU2017228474C1 (en) | 2016-03-04 | 2024-03-28 | Abmuno Therapeutics Llc | Antibodies to TIGIT |
| US10160800B2 (en) * | 2016-06-02 | 2018-12-25 | Medimmune Limited | Antibodies to α-synuclein and uses thereof |
| SG10201912842VA (en) * | 2016-07-14 | 2020-02-27 | Bioarctic Ab | Brain delivery protein |
| KR102550991B1 (ko) | 2016-07-18 | 2023-07-04 | 더 유니버시티 오브 브리티쉬 콜롬비아 | 아밀로이드 베타에 대한 항체 |
| US20180125920A1 (en) | 2016-11-09 | 2018-05-10 | The University Of British Columbia | Methods for preventing and treating A-beta oligomer-associated and/or -induced diseases and conditions |
| MA46836A (fr) | 2016-11-15 | 2019-09-25 | H Lundbeck As | Agents, utilisations et procédés pour le traitement d'une synucléinopathie |
| CN110072888B (zh) | 2016-12-16 | 2023-07-18 | H.隆德贝克有限公司 | 药剂、用途和方法 |
| EP3567054A4 (en) * | 2017-01-06 | 2021-03-10 | ABL Bio Inc. | ANTI-ALPHA SYN ANTIBODIES AND USES THEREOF |
| MX2019008029A (es) * | 2017-01-06 | 2019-12-11 | Abl Bio Inc | Anticuerpo anti-alfa-sinucleina y su uso. |
| EP3583124A1 (en) * | 2017-02-17 | 2019-12-25 | Bristol-Myers Squibb Company | Antibodies to alpha-synuclein and uses thereof |
| US20200148780A1 (en) * | 2017-04-21 | 2020-05-14 | Implicit Bioscience Pty Ltd | Cd 14 antagonist antibodies for treating neurodegenerative diseases |
| WO2018204352A1 (en) * | 2017-05-01 | 2018-11-08 | The Trustees Of The University Of Pennsylvania | Monoclonal antibodies against alpha-synuclein fibrils |
| EP3635393A4 (en) | 2017-05-16 | 2021-03-10 | Claudio Soto-Jara | ABNORMALLY FOLDING TAU PROTEIN DETECTION |
| US12286469B2 (en) | 2017-07-18 | 2025-04-29 | The University Of British Columbia | Humanized antibodies binding to amyloid-beta (A-beta) |
| BR112020001970A2 (pt) | 2017-08-02 | 2020-08-04 | Stressmarq Biosciences Inc. | anticorpo que se liga à alfa-sinucleína ativa |
| WO2019040617A1 (en) | 2017-08-23 | 2019-02-28 | The Trustees Of The University Of Pennsylvania | MONOCLONAL ANTIBODIES AGAINST PATHOLOGICAL ALPHA-SYNUCLEIN AND METHODS USING SAME |
| RU2657763C1 (ru) * | 2017-09-12 | 2018-06-15 | федеральное государственное бюджетное образовательное учреждение высшего образования "Первый Санкт-Петербургский государственный медицинский университет имени академика И.П. Павлова" Министерства здравоохранения Российской Федерации | Способ диагностики болезни паркинсона |
| AU2018370279B2 (en) * | 2017-11-17 | 2022-11-03 | Abl Bio Inc. | Antibodies to a-synuclein and uses thereof |
| JP7212391B2 (ja) | 2017-12-14 | 2023-01-25 | エービーエル バイオ インコーポレイテッド | ａ－ｓｙｎ／ＩＧＦ１Ｒに対する二重特異抗体およびその用途 |
| GB201720970D0 (en) | 2017-12-15 | 2018-01-31 | Ucb Biopharma Sprl | Antibodies |
| GB201720975D0 (en) * | 2017-12-15 | 2018-01-31 | Ucb Biopharma Sprl | Anti-alpha synuclein antibodies |
| PL3728567T3 (pl) | 2017-12-19 | 2023-11-13 | Chase Therapeutics Corporation | Metoda oceny synukleinopatii |
| CN111630382A (zh) * | 2017-12-21 | 2020-09-04 | H.隆德贝克有限公司 | α-共核蛋白病的测定、方法和治疗 |
| CN109957547A (zh) * | 2017-12-25 | 2019-07-02 | 深圳宾德生物技术有限公司 | 一种靶向cd317的嵌合抗原受体t细胞及其制备方法和应用 |
| CN109957546A (zh) * | 2017-12-25 | 2019-07-02 | 深圳宾德生物技术有限公司 | 一种靶向cd317的嵌合抗原受体t细胞及其制备方法和应用 |
| US20210093670A1 (en) * | 2018-04-04 | 2021-04-01 | University Of Florida Research Foundation, Inc. | Materials and methods for the treatment of lewy body disorders |
| US20200017596A1 (en) * | 2018-05-10 | 2020-01-16 | Abvision, Inc. | Monoclonal antibodies activating cd40 and uses thereof |
| WO2020009482A1 (ko) * | 2018-07-03 | 2020-01-09 | 에이비엘바이오 주식회사 | 항 알파-시누클레인 항체 및 그 용도 |
| AU2019309938A1 (en) | 2018-07-24 | 2021-03-11 | Eisai R&D Management Co., Ltd. | Methods of treatment and prevention of alzheimer's disease |
| KR20210081356A (ko) * | 2018-10-19 | 2021-07-01 | 얀센 백신스 앤드 프리벤션 비.브이. | 항-시누클레인 항체 |
| TW202039562A (zh) * | 2018-12-12 | 2020-11-01 | 大陸商上海藥明生物技術有限公司 | 抗tim-3抗體及其用途 |
| RU2703430C1 (ru) * | 2018-12-13 | 2019-10-16 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр глазных болезней имени Гельмгольца" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ ГБ им. Гельмгольца" Минздрава России) | Способ прогнозирования развития нейродегенеративных заболеваний, в основе патогенеза которых лежит гамма-синуклеинопатия |
| TWI734279B (zh) * | 2018-12-14 | 2021-07-21 | 美商美國禮來大藥廠 | 抗α-突觸核蛋白抗體及其用途 |
| EP3946266A4 (en) * | 2019-03-28 | 2023-07-12 | The Chinese University Of Hong Kong | SUMO PEPTIDES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES |
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| RU2760334C2 (ru) * | 2016-12-22 | 2021-11-24 | Х. Лундбекк А/С | Моноклональные антитела к альфа-синуклеину для предотвращения агрегации тау-белка |
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| RU2798399C2 (ru) * | 2017-12-15 | 2023-06-22 | Юсб Биофарма Срл | Антитела |
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