RU2342373C2 - Ацетоновый сольват диметоксидоцетаксела и способ его получения - Google Patents

Ацетоновый сольват диметоксидоцетаксела и способ его получения Download PDF

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Publication number
RU2342373C2
RU2342373C2 RU2006113122/04A RU2006113122A RU2342373C2 RU 2342373 C2 RU2342373 C2 RU 2342373C2 RU 2006113122/04 A RU2006113122/04 A RU 2006113122/04A RU 2006113122 A RU2006113122 A RU 2006113122A RU 2342373 C2 RU2342373 C2 RU 2342373C2
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Russia
Prior art keywords
acetone
hydroxy
water
dimethoxy
benzoyloxy
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RU2006113122/04A
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English (en)
Russian (ru)
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RU2006113122A (ru
Inventor
Эрик ДИДЬЕ (FR)
Эрик Дидье
Марк-Антуан ПЕРРЭН (FR)
Марк-Антуан ПЕРРЭН
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Авентис Фарма С.А.
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Application filed by Авентис Фарма С.А. filed Critical Авентис Фарма С.А.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cephalosporin Compounds (AREA)
RU2006113122/04A 2003-09-19 2004-09-16 Ацетоновый сольват диметоксидоцетаксела и способ его получения RU2342373C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0311016A FR2859996B1 (fr) 2003-09-19 2003-09-19 Solvat acetonique du dimethoxy docetaxel et son procede de preparation
FR0311016 2003-09-19

Publications (2)

Publication Number Publication Date
RU2006113122A RU2006113122A (ru) 2006-08-27
RU2342373C2 true RU2342373C2 (ru) 2008-12-27

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ID=34224354

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Application Number Title Priority Date Filing Date
RU2006113122/04A RU2342373C2 (ru) 2003-09-19 2004-09-16 Ацетоновый сольват диметоксидоцетаксела и способ его получения

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US (1) US7241907B2 (cs)
EP (1) EP1667986B1 (cs)
JP (1) JP5010279B2 (cs)
KR (1) KR101123588B1 (cs)
CN (1) CN100429207C (cs)
AR (1) AR045667A1 (cs)
AU (1) AU2004274212B2 (cs)
BE (1) BE2013C036I2 (cs)
BR (1) BRPI0414492A8 (cs)
CA (1) CA2539309A1 (cs)
CR (1) CR8292A (cs)
CY (2) CY1114575T1 (cs)
DK (1) DK1667986T3 (cs)
ES (1) ES2403149T4 (cs)
FR (2) FR2859996B1 (cs)
HR (1) HRP20130322T1 (cs)
HU (1) HUS1300025I1 (cs)
IL (1) IL174240A (cs)
LU (1) LU92172I2 (cs)
MA (1) MA28045A1 (cs)
ME (2) MEP11708A (cs)
MX (1) MXPA06002639A (cs)
MY (1) MY136668A (cs)
NO (2) NO335997B1 (cs)
NZ (1) NZ545835A (cs)
PA (1) PA8612401A1 (cs)
PE (1) PE20050870A1 (cs)
PL (1) PL1667986T3 (cs)
PT (1) PT1667986E (cs)
RS (2) RS54614B1 (cs)
RU (1) RU2342373C2 (cs)
SI (1) SI1667986T1 (cs)
TN (1) TNSN06086A1 (cs)
TW (1) TWI382022B (cs)
UA (1) UA87115C2 (cs)
WO (1) WO2005028462A1 (cs)
ZA (1) ZA200602255B (cs)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2672110C2 (ru) * 2013-10-23 2018-11-12 Индена С.П.А. Безводная кристаллическая форма кабазитаксела, способ ее получения и фармацевтические композиции

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TWI526437B (zh) * 2011-09-09 2016-03-21 台灣神隆股份有限公司 卡巴他賽之結晶型
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CN103664836B (zh) * 2012-09-20 2016-04-20 齐鲁制药有限公司 7β,10β-二甲氧基多西紫杉醇氘代丙酮合物的晶型A及其制备方法
WO2014055493A1 (en) 2012-10-02 2014-04-10 Cerulean Pharma Inc. Methods and systems for polymer precipitation and generation of particles
CN103804323A (zh) * 2012-11-14 2014-05-21 上海希迈医药科技有限公司 一种卡巴他赛溶剂化物及其制备方法和应用
CN103058960B (zh) * 2012-12-12 2014-12-10 江苏奥赛康药业股份有限公司 卡巴他赛多晶型形式及其制备方法
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CN103910696B (zh) * 2012-12-30 2016-01-20 上海医药工业研究院 卡巴他赛异丙醚合物及其结晶
CN103910698B (zh) * 2012-12-30 2016-01-20 上海医药工业研究院 卡巴他赛丙酮合物及其结晶
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CN104277014A (zh) * 2013-07-04 2015-01-14 北京新天宇科技开发有限公司 二甲氧基多西紫杉醇一丙酮化物的稳定转化物及其结晶形式、以及它们的制备方法
WO2015000165A1 (zh) * 2013-07-04 2015-01-08 北京新天宇科技开发有限公司 二甲氧基多西紫杉醇一丙酮化物的稳定转化物及其结晶形式、以及它们的制备方法
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CN103601704B (zh) * 2013-11-22 2015-05-06 石家庄智恒医药科技有限公司 无定形卡巴他赛的制备
ES2904505T3 (es) 2015-01-12 2022-04-05 Emcure Pharmaceuticals Ltd Formulación líquida de cabazitaxel
PL3258931T3 (pl) * 2015-02-17 2020-12-28 Erasmus University Medical Center Rotterdam Zastosowanie kabazitakselu w leczeniu nowotworu złośliwego prostaty
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CN112703002A (zh) 2018-05-30 2021-04-23 Ptc医疗Mp公司 增加墨蝶呤血浆暴露的方法
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WO1997032869A1 (fr) * 1996-03-06 1997-09-12 Rhone-Poulenc Rorer S.A. Taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
RU97101875A (ru) * 1994-07-08 1999-02-27 Рон-Пуленк Роре С.А. СПОСОБ ПОЛУЧЕНИЯ ТРИГИДРАТА (2R,3S)-3-ТРЕТ-БУТОКСИКАРБОНИЛАМИНО-2-ГИДРОКСИ-3- ФЕНИЛПРОПИОНАТА 4-АЦЕТОКСИ-2α-БЕНЗОИЛОКСИ-5β,,20-ЭПОКСИ- 1,7β,,10β-ТРИГИДРОКСИ-9-ОКСО-ТАКС-11-ЕН-13α-ИЛА

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WO1996003355A1 (de) * 1994-07-22 1996-02-08 Forschungszentrum Karlsruhe Gmbh Verfahren zur herstellung keramischer mikrostrukturen
WO1997032869A1 (fr) * 1996-03-06 1997-09-12 Rhone-Poulenc Rorer S.A. Taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2672110C2 (ru) * 2013-10-23 2018-11-12 Индена С.П.А. Безводная кристаллическая форма кабазитаксела, способ ее получения и фармацевтические композиции

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Publication number Publication date
BE2013C036I2 (cs) 2023-12-14
CY2013016I2 (el) 2018-01-10
CN100429207C (zh) 2008-10-29
RS54614B1 (en) 2016-08-31
AU2004274212B2 (en) 2010-03-04
FR2859996B1 (fr) 2006-02-03
AR045667A1 (es) 2005-11-02
US7241907B2 (en) 2007-07-10
LU92172I9 (cs) 2019-01-03
MXPA06002639A (es) 2006-06-05
ES2403149T3 (es) 2013-05-14
CY1114575T1 (el) 2016-10-05
EP1667986B1 (fr) 2013-01-16
NO2015013I1 (no) 2015-05-04
HK1093340A1 (zh) 2007-03-02
IL174240A (en) 2010-12-30
CR8292A (es) 2008-10-15
ME00054B (me) 2011-02-10
FR13C0037I1 (fr) 2013-09-08
TNSN06086A1 (en) 2007-10-03
MY136668A (en) 2008-11-28
PA8612401A1 (es) 2005-08-04
KR20060072147A (ko) 2006-06-27
ES2403149T4 (es) 2013-06-24
NO335997B1 (no) 2015-04-20
UA87115C2 (ru) 2009-06-25
RS20060189A (en) 2008-06-05
MEP11708A (en) 2010-06-10
FR13C0037I2 (fr) 2015-11-20
SI1667986T1 (sl) 2013-05-31
DK1667986T3 (da) 2013-05-06
TWI382022B (zh) 2013-01-11
RU2006113122A (ru) 2006-08-27
FR2859996A1 (fr) 2005-03-25
NO2015013I2 (no) 2015-04-22
TW200524891A (en) 2005-08-01
LU92172I2 (fr) 2013-05-21
NZ545835A (en) 2009-10-30
IL174240A0 (en) 2006-08-01
MA28045A1 (fr) 2006-07-03
CY2013016I1 (el) 2018-01-10
EP1667986A1 (fr) 2006-06-14
JP2007505866A (ja) 2007-03-15
NO20061714L (no) 2006-04-19
PL1667986T3 (pl) 2013-06-28
AU2004274212A1 (en) 2005-03-31
BRPI0414492A8 (pt) 2019-01-15
CN1849311A (zh) 2006-10-18
HRP20130322T1 (en) 2013-07-31
ZA200602255B (en) 2007-07-25
KR101123588B1 (ko) 2012-03-22
PT1667986E (pt) 2013-04-24
HUS1300025I1 (hu) 2016-08-29
US20050065138A1 (en) 2005-03-24
BRPI0414492A (pt) 2006-11-14
PE20050870A1 (es) 2005-11-21
CA2539309A1 (fr) 2005-03-31
WO2005028462A1 (fr) 2005-03-31
JP5010279B2 (ja) 2012-08-29

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