RU2237670C1 - Способ взаимодействия и промежуточные продукты, пригодные для получения цефалоспоринов - Google Patents

Способ взаимодействия и промежуточные продукты, пригодные для получения цефалоспоринов Download PDF

Info

Publication number
RU2237670C1
RU2237670C1 RU2003116519/04A RU2003116519A RU2237670C1 RU 2237670 C1 RU2237670 C1 RU 2237670C1 RU 2003116519/04 A RU2003116519/04 A RU 2003116519/04A RU 2003116519 A RU2003116519 A RU 2003116519A RU 2237670 C1 RU2237670 C1 RU 2237670C1
Authority
RU
Russia
Prior art keywords
alkyl
formula
aryl
compound
group
Prior art date
Application number
RU2003116519/04A
Other languages
English (en)
Russian (ru)
Other versions
RU2003116519A (ru
Inventor
Хуан Карлос КОЛБЕРГ (US)
Хуан Карлос КОЛБЕРГ
Алессандро ДОНАДЕЛЛИ (IT)
Алессандро ДОНАДЕЛЛИ
Джованни ФОЛЬЯТО (IT)
Джованни ФОЛЬЯТО
Маурицио ДЗЕНОНИ (IT)
Маурицио ДЗЕНОНИ
Original Assignee
Пфайзер Продактс Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пфайзер Продактс Инк. filed Critical Пфайзер Продактс Инк.
Application granted granted Critical
Publication of RU2237670C1 publication Critical patent/RU2237670C1/ru
Publication of RU2003116519A publication Critical patent/RU2003116519A/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C07D501/06—Acylation of 7-aminocephalosporanic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
RU2003116519/04A 2000-12-04 2001-11-22 Способ взаимодействия и промежуточные продукты, пригодные для получения цефалоспоринов RU2237670C1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25101400P 2000-12-04 2000-12-04
US60/251,014 2000-12-04

Publications (2)

Publication Number Publication Date
RU2237670C1 true RU2237670C1 (ru) 2004-10-10
RU2003116519A RU2003116519A (ru) 2004-12-27

Family

ID=22950114

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2003116519/04A RU2237670C1 (ru) 2000-12-04 2001-11-22 Способ взаимодействия и промежуточные продукты, пригодные для получения цефалоспоринов

Country Status (17)

Country Link
US (2) US20020198375A1 (enExample)
EP (1) EP1339722A1 (enExample)
JP (1) JP2004520293A (enExample)
KR (1) KR100526379B1 (enExample)
CN (1) CN1243755C (enExample)
AR (1) AR035511A1 (enExample)
AU (2) AU2002223943B2 (enExample)
BR (1) BR0115870A (enExample)
CA (1) CA2436848C (enExample)
CZ (1) CZ20031525A3 (enExample)
HU (1) HUP0400642A3 (enExample)
IL (1) IL155714A0 (enExample)
MX (1) MXPA03004937A (enExample)
PL (1) PL362144A1 (enExample)
RU (1) RU2237670C1 (enExample)
WO (1) WO2002046198A1 (enExample)
ZA (1) ZA200303670B (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1232512C (zh) * 2000-12-04 2005-12-21 藤泽药品工业株式会社 氨基噻唑衍生物的无水物的制备方法
US7378408B2 (en) * 2001-11-30 2008-05-27 Pfizer Inc. Methods of treatment and formulations of cephalosporin
CN1930173A (zh) * 2004-03-09 2007-03-14 辉瑞产品公司 使用α－碘代－1－氮杂环丁烷乙酸酯和三烷基亚磷酸盐制备头孢菌素中间体的方法
EP2705077B1 (en) 2011-05-04 2019-11-20 Cornell University Multiblock copolymer films, methods of making same, and uses thereof
KR20140051998A (ko) 2011-08-03 2014-05-02 교와 핫꼬 기린 가부시키가이샤 디벤조옥세핀 유도체
CN102718779B (zh) * 2012-05-25 2015-07-29 深圳致君制药有限公司 注射用头孢唑肟钠及其制备方法、原料药头孢唑肟钠的合成方法
CN105254648B (zh) * 2015-11-13 2018-04-03 广东温氏大华农生物科技有限公司 一种头孢维星及其钠盐的合成方法
WO2018229580A1 (en) * 2017-06-14 2018-12-20 Aurobindo Pharma Ltd An improved process for the preparation of cefovecin sodium
KR102629981B1 (ko) 2017-09-19 2024-01-29 테라포어 테크놀로지스, 인코포레이티드 내화학성 이소포러스 가교 블록 코폴리머 구조
CA3095610A1 (en) * 2018-04-04 2019-10-10 Terapore Technologies, Inc. Encapsulating particle fractionation devices and systems and methods of their use
GB2575261B (en) 2018-07-02 2022-03-09 Norbrook Lab Ltd Intermediates in the synthesis of C3-substituted cephalosporins
US11051804B2 (en) * 2018-07-02 2021-07-06 DePuy Synthes Products, Inc. Orthopedic fixation system and method of use thereof
CN110396034A (zh) * 2019-07-31 2019-11-01 上海应用技术大学 一种烯丙基化合物的制备方法
CN111187284A (zh) * 2020-03-10 2020-05-22 赵俊瑶 一种头孢克洛的制备方法
CN111892612A (zh) * 2020-07-31 2020-11-06 重庆医药高等专科学校 一种以青霉素钾盐为原料制备头孢维星的中间体异构化物及其制备方法
CN112321611B (zh) * 2020-10-29 2022-05-06 湖北凌晟药业有限公司 一种头孢沙定母核的制备方法
CN115873021A (zh) * 2022-12-19 2023-03-31 华北制药集团动物保健品有限责任公司 一种头孢维星钠的制备方法
CN116731039B (zh) * 2023-06-12 2025-02-18 重庆汉佩生物科技有限公司 头孢维星衍生物的制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992001695A1 (en) * 1990-07-24 1992-02-06 Beecham Group Plc Cephalosporins and homologues, preparations and pharmaceutical compositions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001997A (en) * 1990-07-24 1999-12-14 Bateson; John Hargreaves Cephalosporins and homologues, preparations and pharmaceutical compositions
GB9212609D0 (en) * 1992-06-13 1992-07-29 Smithkline Beecham Plc Novel compounds
GB9424847D0 (en) * 1994-12-09 1995-02-08 Smithkline Beecham Plc Novel process
GB2300856A (en) * 1995-05-16 1996-11-20 Pfizer Ltd Beta-lactam preparation
GB0019124D0 (en) * 2000-08-03 2000-09-27 Pfizer Novel process
DK1339723T3 (da) * 2000-12-04 2006-06-12 Pfizer Prod Inc Fremgangsmåde og ester derivater anvendelige til fremstilling af cefalosporiner

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992001695A1 (en) * 1990-07-24 1992-02-06 Beecham Group Plc Cephalosporins and homologues, preparations and pharmaceutical compositions
WO1992001696A1 (en) * 1990-07-24 1992-02-06 Beecham Group Plc Cephalosporins and homologues, preparations and pharmaceutical compositions

Also Published As

Publication number Publication date
US20020198375A1 (en) 2002-12-26
JP2004520293A (ja) 2004-07-08
HUP0400642A3 (en) 2010-03-29
CA2436848A1 (en) 2002-06-13
EP1339722A1 (en) 2003-09-03
MXPA03004937A (es) 2003-09-10
HK1059435A1 (en) 2004-07-02
CN1478093A (zh) 2004-02-25
HUP0400642A2 (hu) 2004-06-28
KR20030070043A (ko) 2003-08-27
ZA200303670B (en) 2004-05-13
PL362144A1 (en) 2004-10-18
AU2394302A (en) 2002-06-18
CZ20031525A3 (cs) 2004-04-14
BR0115870A (pt) 2004-02-03
AU2002223943B2 (en) 2006-10-05
WO2002046198A1 (en) 2002-06-13
AR035511A1 (es) 2004-06-02
KR100526379B1 (ko) 2005-11-08
CA2436848C (en) 2008-12-02
US20040167327A1 (en) 2004-08-26
CN1243755C (zh) 2006-03-01
IL155714A0 (en) 2003-11-23
US7129350B2 (en) 2006-10-31

Similar Documents

Publication Publication Date Title
KR100526379B1 (ko) 세팔로스포린 제조에 유용한 커플링법 및 중간체
US4396620A (en) Cephalosporin quinolinium betaines
AU2002223943A1 (en) Coupling process and intermediates useful for preparing cephalosphorins
NO881531L (no) Acylderivater.
US4369313A (en) Intermediates for use in the preparation of cephalosporin antibiotics
US5804577A (en) Cephalosporin derivatives
NO170021B (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive 3-propenylcefem-derivater
HU189014B (en) Process for producing fluoro-methylthio-oxa-cepheme-carboxylic acid derivatives
KR100526380B1 (ko) 세팔로스포린을 제조하는데 유용한 방법 및 에스테르유도체
US4935508A (en) Process for cephem prodrug esters
US4381263A (en) Process for the preparation of penicillanic acid esters
US5028427A (en) "Cephalosporin" compounds
AU2002223929A1 (en) Process and ester derivatives useful for preparation of cephalosporins
JPH03220195A (ja) ３―フルオロスルホニルオキシセフ―３―エム置換法
US4521598A (en) 3-Azidocephalosporins
US4160091A (en) Process for preparation of 3-halo-3-methylcephams
US4560749A (en) Cephem-3-imidates and 3-amidines
JP2004168775A (ja) オキサセファロスポリンの改良合成法
NO743991L (enExample)
KR960011778B1 (ko) 신규한 결정성 세팔로스포린 유도체의 제조방법
KR0136053B1 (ko) 신규 세팔로스포린계 항생제 및 이의 제조방법
HK1059435B (zh) 用於制备头孢菌素的偶合方法和中间体
JPS6318956B2 (enExample)
JPS63211283A (ja) 抗菌剤
CZ577290A3 (cs) 3-/Fluorsulfonyl/oxy substituovaný cefem, oxacefem a karbacefem a způsob jejich přípravy