RU2146256C1 - ПРОИЗВОДНЫЕ АЗОЛА И ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ НА ИХ ОСНОВЕ С АКТИВНОСТЬЮ В ОТНОШЕНИИ СЕРОТОНИНОВОГО (5-HT1Dα)РЕЦЕПТОРА - Google Patents
ПРОИЗВОДНЫЕ АЗОЛА И ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ НА ИХ ОСНОВЕ С АКТИВНОСТЬЮ В ОТНОШЕНИИ СЕРОТОНИНОВОГО (5-HT1Dα)РЕЦЕПТОРА Download PDFInfo
- Publication number
- RU2146256C1 RU2146256C1 RU95115522A RU95115522A RU2146256C1 RU 2146256 C1 RU2146256 C1 RU 2146256C1 RU 95115522 A RU95115522 A RU 95115522A RU 95115522 A RU95115522 A RU 95115522A RU 2146256 C1 RU2146256 C1 RU 2146256C1
- Authority
- RU
- Russia
- Prior art keywords
- alkyl
- mmol
- mixture
- tetrahydro
- pyrido
- Prior art date
Links
- 0 CC(CC1*C2=*)C=CC1C2=C=C Chemical compound CC(CC1*C2=*)C=CC1C2=C=C 0.000 description 4
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Addiction (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Otolaryngology (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Optical Integrated Circuits (AREA)
- Holo Graphy (AREA)
- Gyroscopes (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9418326.6 | 1994-09-12 | ||
| GB9418326A GB9418326D0 (en) | 1994-09-12 | 1994-09-12 | Pharmaceutical compounds |
| GBGB9511166.2A GB9511166D0 (en) | 1995-06-02 | 1995-06-02 | Pharmaceutical compounds |
| GB9511166.2 | 1995-06-02 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU95115522A RU95115522A (ru) | 1997-08-27 |
| RU2146256C1 true RU2146256C1 (ru) | 2000-03-10 |
Family
ID=26305611
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU95115522A RU2146256C1 (ru) | 1994-09-12 | 1995-09-11 | ПРОИЗВОДНЫЕ АЗОЛА И ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ НА ИХ ОСНОВЕ С АКТИВНОСТЬЮ В ОТНОШЕНИИ СЕРОТОНИНОВОГО (5-HT1Dα)РЕЦЕПТОРА |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP0705832B1 (OSRAM) |
| JP (1) | JPH0881464A (OSRAM) |
| KR (1) | KR960010635A (OSRAM) |
| CN (1) | CN1045602C (OSRAM) |
| AT (1) | ATE247114T1 (OSRAM) |
| AU (1) | AU698580B2 (OSRAM) |
| CA (1) | CA2157998A1 (OSRAM) |
| CZ (1) | CZ286565B6 (OSRAM) |
| DE (1) | DE69531476T2 (OSRAM) |
| ES (1) | ES2204932T3 (OSRAM) |
| FI (1) | FI954243A7 (OSRAM) |
| HU (1) | HU219491B (OSRAM) |
| IL (1) | IL115236A (OSRAM) |
| IN (1) | IN179550B (OSRAM) |
| MY (1) | MY132009A (OSRAM) |
| NO (1) | NO305174B1 (OSRAM) |
| NZ (1) | NZ272961A (OSRAM) |
| PE (1) | PE41796A1 (OSRAM) |
| PH (1) | PH31631A (OSRAM) |
| PL (1) | PL310373A1 (OSRAM) |
| RU (1) | RU2146256C1 (OSRAM) |
| TR (1) | TR199501114A2 (OSRAM) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2232578C1 (ru) * | 2003-04-10 | 2004-07-20 | Ахапкина Валентина Ивановна | Вещество, обладающее антидепрессивной активностью |
| RU2745742C1 (ru) * | 2015-10-01 | 2021-03-31 | Олема Фармасьютикалз, Инк. | ТЕТРАГИДРО-1Н-ПИРИДО[3,4-b]ИНДОЛЬНЫЕ АНТИЭСТРОГЕННЫЕ ЛЕКАРСТВЕННЫЕ СРЕДСТВА |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2308362A (en) * | 1995-12-19 | 1997-06-25 | Lilly Industries Ltd | Pharmaceutical indole derivatives |
| EP0905136A1 (en) * | 1997-09-08 | 1999-03-31 | Janssen Pharmaceutica N.V. | Tetrahydro gamma-carbolines |
| UA70334C2 (en) * | 1998-10-06 | 2004-10-15 | Janssen Pharmaceutica N V Jans | BENZOTHIENO[3,2-c]PYRIDINES AS a2 ANTAGONISTS BENZOTHIENO[3,2-c]PYRIDINES AS a2 ANTAGONISTS |
| UA74826C2 (en) * | 2000-05-17 | 2006-02-15 | Ortho Mcneil Pharm Inc | ?-carboline derivatives as phosphodiesterase inhibitors |
| CA2415815A1 (en) * | 2000-07-06 | 2002-01-17 | Nigel H. Greig | Tetrahydrobenzothiazole analogues as neuroprotective agents |
| DE10040016A1 (de) * | 2000-08-16 | 2002-02-28 | Boehringer Ingelheim Pharma | Neue beta-Amyloid Inhibitoren, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| EP1322622B1 (en) * | 2000-09-19 | 2012-10-31 | Sprout Pharmaceuticals, Inc. | New n, n'-disubstituted benzimidazolone derivatives with affinity at the serotonin and dopamine receptors |
| US6586435B2 (en) | 2000-09-19 | 2003-07-01 | Boehringer Ingelheim Pharma Kg | Benzimidazolone derivatives displaying affinity at the serotonin and dopamine receptors |
| MXPA03002329A (es) * | 2000-09-19 | 2003-10-15 | Boehringer Ingelheim Pharma | Nuevos derivados de bencimidazolona que muestran afinidad por los receptores de serotonina y dopamina. |
| US7183410B2 (en) | 2001-08-02 | 2007-02-27 | Bidachem S.P.A. | Stable polymorph of flibanserin |
| MXPA04001203A (es) * | 2001-08-08 | 2004-05-20 | Pharmacia & Upjhon Company | 1-h-pirido[4,3-b] indoles terapeuticos. |
| UA78974C2 (en) | 2001-10-20 | 2007-05-10 | Boehringer Ingelheim Pharma | Use of flibanserin for treating disorders of sexual desire |
| US10675280B2 (en) | 2001-10-20 | 2020-06-09 | Sprout Pharmaceuticals, Inc. | Treating sexual desire disorders with flibanserin |
| EP1912650B8 (en) | 2005-08-03 | 2017-10-18 | Sprout Pharmaceuticals, Inc. | Use of flibanserin in the treatment of obesity |
| JP2009513604A (ja) | 2005-10-29 | 2009-04-02 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 月経前障害及び他の女性の性的障害治療用のベンゾイミダゾロン誘導体 |
| ATE456369T1 (de) | 2006-06-30 | 2010-02-15 | Boehringer Ingelheim Int | Flibanserin zur behandlung von harninkontinenz und assoziierten erkrankungen |
| MX2009001551A (es) | 2006-08-14 | 2009-02-20 | Boehringer Ingelheim Int | Formulaciones de flibanserina y metodo para fabricarlas. |
| CL2007002214A1 (es) | 2006-08-14 | 2008-03-07 | Boehringer Ingelheim Int | Composicion farmaceutica en la forma de comprimido, donde al menos la longitud del comprimido en el estado anterior de la aplicacion es al menos 7/12 del diametro pilorico del paciente y despues de ingerirlo en estado alimentado, la longitud del comp |
| CA2661613C (en) | 2006-08-25 | 2016-01-26 | Boehringer Ingelheim International Gmbh | Controlled release system and method for manufacturing the same |
| PE20091188A1 (es) | 2007-09-12 | 2009-08-31 | Boehringer Ingelheim Int | Compuesto 1-[2-(4-(3-trifluorometil-fenil)piperazin-1-il)etil]-2,3-dihidro-1h-benzimidazol-2-ona (flibanserina), sus sales de adicion y composiciones farmaceuticas que los contienen |
| US8829035B2 (en) | 2009-05-29 | 2014-09-09 | Sumitomo Chemical Company, Limited | Agent for treatment or prevention of diseases associated with activity of neurotrophic factors |
| CA3144791A1 (en) | 2019-07-07 | 2021-01-14 | Olema Pharmaceuticals, Inc. | Regimens of estrogen receptor antagonists |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1442074A3 (ru) * | 1985-09-16 | 1988-11-30 | Американ Хоум Продактс Корпорейшн (Фирма) | Способ получени производных @ -карболина или их фармацевтически приемлемых солей |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4035369A (en) | 1975-10-08 | 1977-07-12 | Janssen Pharmaceutica N.V. | 1-Benzazolylalkyl-4-substituted-piperidines |
| IL69132A (en) * | 1982-07-14 | 1986-02-28 | Roussel Uclaf | Benzo-and naphtho-thiopyranopyrimidinones,their preparation and pharmaceutical compositions containing them |
| FR2661177A1 (fr) * | 1990-04-23 | 1991-10-25 | Rhone Poulenc Sante | Derives du naphtosultame antagonistes de la serotonine, leur preparation et les medicaments les contenant. |
-
1995
- 1995-09-07 DE DE69531476T patent/DE69531476T2/de not_active Expired - Fee Related
- 1995-09-07 EP EP95306253A patent/EP0705832B1/en not_active Expired - Lifetime
- 1995-09-07 AT AT95306253T patent/ATE247114T1/de not_active IP Right Cessation
- 1995-09-07 ES ES95306253T patent/ES2204932T3/es not_active Expired - Lifetime
- 1995-09-08 HU HU9502631A patent/HU219491B/hu not_active IP Right Cessation
- 1995-09-08 MY MYPI95002675A patent/MY132009A/en unknown
- 1995-09-08 NZ NZ272961A patent/NZ272961A/en unknown
- 1995-09-08 PH PH51266A patent/PH31631A/en unknown
- 1995-09-08 AU AU30497/95A patent/AU698580B2/en not_active Ceased
- 1995-09-08 CZ CZ19952322A patent/CZ286565B6/cs not_active IP Right Cessation
- 1995-09-11 NO NO953575A patent/NO305174B1/no not_active IP Right Cessation
- 1995-09-11 JP JP7231873A patent/JPH0881464A/ja active Pending
- 1995-09-11 PL PL95310373A patent/PL310373A1/xx unknown
- 1995-09-11 KR KR1019950029475A patent/KR960010635A/ko not_active Ceased
- 1995-09-11 FI FI954243A patent/FI954243A7/fi unknown
- 1995-09-11 RU RU95115522A patent/RU2146256C1/ru active
- 1995-09-11 IN IN1079CA1995 patent/IN179550B/en unknown
- 1995-09-11 IL IL115236A patent/IL115236A/en not_active IP Right Cessation
- 1995-09-11 CN CN95117133A patent/CN1045602C/zh not_active Expired - Fee Related
- 1995-09-11 CA CA002157998A patent/CA2157998A1/en not_active Abandoned
- 1995-09-12 TR TR95/01114A patent/TR199501114A2/xx unknown
- 1995-09-12 PE PE1995278830A patent/PE41796A1/es not_active Application Discontinuation
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1442074A3 (ru) * | 1985-09-16 | 1988-11-30 | Американ Хоум Продактс Корпорейшн (Фирма) | Способ получени производных @ -карболина или их фармацевтически приемлемых солей |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2232578C1 (ru) * | 2003-04-10 | 2004-07-20 | Ахапкина Валентина Ивановна | Вещество, обладающее антидепрессивной активностью |
| RU2745742C1 (ru) * | 2015-10-01 | 2021-03-31 | Олема Фармасьютикалз, Инк. | ТЕТРАГИДРО-1Н-ПИРИДО[3,4-b]ИНДОЛЬНЫЕ АНТИЭСТРОГЕННЫЕ ЛЕКАРСТВЕННЫЕ СРЕДСТВА |
| US11229630B2 (en) | 2015-10-01 | 2022-01-25 | Olema Pharmaceuticals, Inc. | Tetrahydro-1H-pyrido [3,4-b]indole anti-estrogenic drugs |
| US11672785B2 (en) | 2015-10-01 | 2023-06-13 | Olema Pharmaceuticals, Inc. | Tetrahydro-1H-pyrido [3,4-b]indole anti-estrogenic drugs |
Also Published As
| Publication number | Publication date |
|---|---|
| AU698580B2 (en) | 1998-11-05 |
| PE41796A1 (es) | 1996-10-21 |
| MY132009A (en) | 2007-09-28 |
| HU9502631D0 (en) | 1995-11-28 |
| DE69531476T2 (de) | 2004-06-09 |
| HU219491B (hu) | 2001-04-28 |
| IN179550B (OSRAM) | 1997-10-18 |
| PL310373A1 (en) | 1996-03-18 |
| DE69531476D1 (de) | 2003-09-18 |
| ATE247114T1 (de) | 2003-08-15 |
| IL115236A (en) | 1998-06-15 |
| CZ286565B6 (cs) | 2000-05-17 |
| NO953575D0 (no) | 1995-09-11 |
| EP0705832A1 (en) | 1996-04-10 |
| CZ232295A3 (en) | 1996-03-13 |
| NO953575L (no) | 1996-03-13 |
| JPH0881464A (ja) | 1996-03-26 |
| PH31631A (en) | 1999-01-12 |
| CA2157998A1 (en) | 1996-03-13 |
| KR960010635A (ko) | 1996-04-20 |
| CN1045602C (zh) | 1999-10-13 |
| ES2204932T3 (es) | 2004-05-01 |
| NZ272961A (en) | 1998-02-26 |
| EP0705832B1 (en) | 2003-08-13 |
| TR199501114A2 (tr) | 1996-10-21 |
| AU3049795A (en) | 1996-03-28 |
| FI954243A7 (fi) | 1996-03-13 |
| CN1129219A (zh) | 1996-08-21 |
| HUT72593A (en) | 1996-05-28 |
| IL115236A0 (en) | 1995-12-31 |
| FI954243A0 (fi) | 1995-09-11 |
| NO305174B1 (no) | 1999-04-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2146256C1 (ru) | ПРОИЗВОДНЫЕ АЗОЛА И ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ НА ИХ ОСНОВЕ С АКТИВНОСТЬЮ В ОТНОШЕНИИ СЕРОТОНИНОВОГО (5-HT1Dα)РЕЦЕПТОРА | |
| DK174161B1 (da) | Anellerede indolderivater, fremgangsmåde til deres fremstilling og fremgangsmåde til fremstilling af farmaceutisk præparat indeholdende dem | |
| AU702548B2 (en) | Chemical compounds | |
| EP0666858B1 (en) | 5-arylindole derivatives and their use as serotonin (5-ht 1) agonists | |
| AU671836B2 (en) | Fused imidazole and triazole derivatives as 5-HT1 receptor agonists | |
| EP0397060A2 (de) | Maleinimid-Derivate und deren Verwendung als Arzneimittel | |
| JPH06279442A (ja) | ピロロ−ピリジン誘導体 | |
| US5563147A (en) | Serotonerbic tetrahydropyridoindoles | |
| CN110023291A (zh) | 三环rho激酶抑制剂 | |
| NZ264596A (en) | Imidazol-4-ylpiperidines; compounds, preparation and pharmaceutical compositions containing them | |
| EP0730593A1 (en) | Morpholine derivatives as dopamine receptor subtype ligands | |
| WO2001032660A1 (en) | Compounds having 5-ht6 receptor antagonist activity | |
| PL210413B1 (pl) | Pochodne indoliloalkiloaminy | |
| AU779832B2 (en) | Azaindoles having serotonin receptor affinity | |
| RS63671B1 (sr) | Supstitutisani derivati triazolo hinoksalina | |
| DD297970A5 (de) | Verfahren zur herstellung von be1-(1h-indol-3-yl)-maleinimid-derivaten und deren verwendung | |
| RS51605B (sr) | 3-fenil supstituisani piridoindolon, njegova izrada i terapeutska upotreba | |
| WO2015012704A1 (en) | Pyrroloquinoline derivatives as 5-ht6 antagonists, preparation method and use thereof | |
| JPH09502449A (ja) | ドーパミン受容体サブタイプリガンドとしての縮合三環複素芳香族誘導体 | |
| FI83220B (fi) | Foerfarande foer framstaellning av terapeutiskt anvaendbara 1,3-dimetyl-1h-purin-2,6-dionderivat. | |
| US6897215B1 (en) | Compounds having 5-HT6 receptor antagonist activity | |
| FR2868422A1 (fr) | Nouveaux derives pyrrolo(2,3-b) pyridine, leur preparation et leur utilisation pharmaceutique comme inhibiteurs de kinases | |
| TW589312B (en) | Aryl-8-azabicyclo[3.2.1]octanes for the treatment of depression | |
| EA001469B1 (ru) | Замещенные 4-(6-фтор-(1н)-индол-3-ил)-1,2,3,6-тетрагидропиридин для лечения нарушений центральной нервной системы | |
| JPH09508637A (ja) | ５ｈｔ２ｂレセプタ拮抗薬縮合インドール |