RU2134104C1 - Пероральная композиция для лечения воспалительных заболеваний кишечного тракта - Google Patents

Пероральная композиция для лечения воспалительных заболеваний кишечного тракта Download PDF

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Publication number
RU2134104C1
RU2134104C1 SU5052239A SU5052239A RU2134104C1 RU 2134104 C1 RU2134104 C1 RU 2134104C1 SU 5052239 A SU5052239 A SU 5052239A SU 5052239 A SU5052239 A SU 5052239A RU 2134104 C1 RU2134104 C1 RU 2134104C1
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RU
Russia
Prior art keywords
budesonide
isomer
dosage form
water
form according
Prior art date
Application number
SU5052239A
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English (en)
Russian (ru)
Inventor
Ульмиюс Ян
Original Assignee
Актиеболагет Драко
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20377544&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RU2134104(C1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Актиеболагет Драко filed Critical Актиеболагет Драко
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Publication of RU2134104C1 publication Critical patent/RU2134104C1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Plant Substances (AREA)
SU5052239A 1989-11-22 1990-11-15 Пероральная композиция для лечения воспалительных заболеваний кишечного тракта RU2134104C1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE8903914-3 1989-11-22
SE8903914A SE8903914D0 (sv) 1989-11-22 1989-11-22 Oral composition for the treatment of inflammatory bowel diseases
PCT/SE1990/000738 WO1991007172A1 (en) 1989-11-22 1990-11-15 Oral composition for the treatment of inflammatory bowel diseases

Publications (1)

Publication Number Publication Date
RU2134104C1 true RU2134104C1 (ru) 1999-08-10

Family

ID=20377544

Family Applications (1)

Application Number Title Priority Date Filing Date
SU5052239A RU2134104C1 (ru) 1989-11-22 1990-11-15 Пероральная композиция для лечения воспалительных заболеваний кишечного тракта

Country Status (36)

Country Link
US (1) US6423340B1 (https=)
EP (1) EP0502092B1 (https=)
JP (1) JP3145111B2 (https=)
KR (1) KR0179042B1 (https=)
AT (1) ATE125445T1 (https=)
AU (1) AU643021B2 (https=)
CA (1) CA2071518C (https=)
DE (1) DE69021214T2 (https=)
DK (1) DK0502092T3 (https=)
EG (1) EG19642A (https=)
ES (1) ES2074698T3 (https=)
FI (2) FI104949B (https=)
GR (1) GR3017691T3 (https=)
HK (1) HK51897A (https=)
HR (1) HRP920632B1 (https=)
HU (2) HUT60630A (https=)
IE (1) IE74854B1 (https=)
IL (1) IL96415A (https=)
IS (1) IS1858B (https=)
LT (1) LT3696B (https=)
LV (1) LV10183B (https=)
MY (1) MY104535A (https=)
NO (1) NO304010B1 (https=)
NZ (1) NZ235807A (https=)
PL (1) PL166506B1 (https=)
PT (1) PT95946A (https=)
RU (1) RU2134104C1 (https=)
SA (1) SA90110123B1 (https=)
SE (1) SE8903914D0 (https=)
SG (1) SG54210A1 (https=)
SI (1) SI9012150A (https=)
TW (1) TW250435B (https=)
UA (1) UA37196C2 (https=)
WO (1) WO1991007172A1 (https=)
YU (1) YU48583B (https=)
ZA (1) ZA908777B (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD480Z5 (ro) * 2011-07-07 2012-09-30 Эльвира АНДОН Metodă de tratament al colitei ulceroase nespecifice acute
RU2750937C2 (ru) * 2016-02-09 2021-07-06 Альбирео Аб Пероральный состав холестирамина и его применение
RU2750944C2 (ru) * 2016-02-09 2021-07-06 Альбирео Аб Пероральный состав холестирамина и его применение

Families Citing this family (32)

* Cited by examiner, † Cited by third party
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US5316772A (en) * 1990-12-19 1994-05-31 Solvay & Cie, S.A. (Societe Anonyme) Bilayered oral pharmaceutical composition with pH dependent release
CA2152374A1 (en) * 1993-01-08 1994-07-21 Ralph Lennart Brattsand Novel colon- or ileum-specific steroid derivatives
US5914132A (en) * 1993-02-26 1999-06-22 The Procter & Gamble Company Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery
DE4332394A1 (de) * 1993-09-23 1995-03-30 Falk Pharma Gmbh Budesonid-Pellets mit kontrolliertem Freigabeprofil und Verfahren zu ihrer Herstellung
US5686106A (en) * 1995-05-17 1997-11-11 The Procter & Gamble Company Pharmaceutical dosage form for colonic delivery
KR20000053327A (ko) * 1996-11-15 2000-08-25 데이비드 엠 모이어 결장내 운반에 사용되는 약학적 제형
SE9604751D0 (sv) 1996-12-20 1996-12-20 Astra Ab New therapy
DE19732903A1 (de) 1997-07-30 1999-02-04 Falk Pharma Gmbh Pellet-Formulierung zur Behandlung des Intestinaltraktes
US6239120B1 (en) 1998-03-17 2001-05-29 Pharmalink Ab Method and means for treating glomerulonephritis
GB9824604D0 (en) 1998-11-11 1999-01-06 Hewlett Healthcare Limited Treatment of allergic conditions
SE9902673D0 (sv) * 1999-07-12 1999-07-12 Astra Ab New composition
WO2002074316A1 (en) * 2001-03-15 2002-09-26 Enteron Pharmaceuticals, Inc. Method of treating inflammatory disorders of the gastrointestinal tract using topical active corticosteroids
DE10250543A1 (de) * 2002-10-29 2004-05-19 Röhm GmbH & Co. KG Mehrschichtige Arzneiform
ES2312844T3 (es) 2002-12-12 2009-03-01 Nycomed Gmbh Medicamento de combinacion de r, r-formoterol y ciclesonida.
WO2004087109A1 (ja) * 2003-03-27 2004-10-14 Hisamitsu Pharmaceutical Co., Inc. 大腸送達性経口医薬製剤、大腸癌治療用経口医薬製剤および大腸炎治療用経口医薬製剤
DE602004028497D1 (de) * 2003-09-15 2010-09-16 Nycomed Gmbh Verwendung von ciclesonid zur behandlung von entzündlichen darmerkrankungen
AU2004271744B2 (en) 2003-09-16 2010-07-29 Covis Pharma B.V. Use of ciclesonide for the treatment of respiratory diseases
US8461187B2 (en) 2004-06-16 2013-06-11 Takeda Pharmaceuticals U.S.A., Inc. Multiple PPI dosage form
WO2007056539A2 (en) * 2005-11-08 2007-05-18 Medarex, Inc. Prophylaxis and treatment of enterocolitis associated with anti-ctla-4 antibody therapy
US20100209520A1 (en) * 2007-03-26 2010-08-19 Hiroyuki Kubo Oral pharmaceutical preparation for colon-specific delivery
SG185296A1 (en) * 2007-10-12 2012-11-29 Takeda Pharmaceuticals Usa Inc Methods of treating gastrointestinal disorders independent of the intake of food
GB0808537D0 (en) 2008-05-12 2008-06-18 Archimedes Dev Ltd Compositions
CN102238868A (zh) * 2008-10-03 2011-11-09 福尔克博士药物有限责任公司 使用颗粒状5-氨基水杨酸治疗肠病的组合物和方法
US8945616B2 (en) 2009-02-17 2015-02-03 Mylan Pharmaceuticals Inc. Controlled release budesonide minitablets
US8945615B2 (en) * 2009-02-17 2015-02-03 Mylan Pharmaceuticals Inc. Controlled release budesonide minitablets
EP2670407A4 (en) * 2011-02-04 2014-07-23 Optimer Pharmaceuticals Inc TREATMENT OF BACTERIAL INFECTIONS
PL2659881T3 (pl) 2012-04-30 2018-05-30 Tillotts Pharma Ag Formulacja leku o opóźnionym uwalnianiu
JP6273356B2 (ja) 2013-10-29 2018-01-31 ティロッツ・ファルマ・アクチエンゲゼルシャフトＴｉｌｌｏｔｔｓ Ｐｈａｒｍａ Ａｇ 遅延放出性薬物製剤
EP3346996A4 (en) * 2015-09-11 2019-04-17 Sun Pharmaceutical Industries Limited ORAL PHARMACEUTICAL PHARMACEUTICAL FORM OF BUDESONID
CN105663091A (zh) * 2016-01-28 2016-06-15 上海信谊百路达药业有限公司 一种布地奈德肠溶缓释胶囊及其制备方法
EP3613414A1 (de) 2018-08-24 2020-02-26 Dr. Falk Pharma Gmbh Pellets mit mehrschichtiger struktur zur verzögerten freisetzung des wirkstoffs im distalen kolon
US11896719B2 (en) 2022-01-24 2024-02-13 Calliditas Therapeutics Ab Pharmaceutical compositions

Citations (2)

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WO1983000435A1 (en) * 1981-07-31 1983-02-17 Rhodes, John Orally administrable pharmaceutical compositions
EP0278174A2 (en) * 1986-12-24 1988-08-17 Glaxo Group Limited Use of fluticasone propionate in the preparation of a pharmaceutical composition for the treatment of bowel diseases

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US3996356A (en) 1969-07-02 1976-12-07 Hoffmann-La Roche Inc. Composition containing 5-sulfanilamido-3,4-dimethylisoxazole and a trimethoxybenzyl pyrimidine
SE378109B (https=) 1972-05-19 1975-08-18 Bofors Ab
SE7813246L (sv) 1978-12-22 1980-06-23 Haessle Ab Fast farmaceutisk beredning innehallande kroppar med flera ytskikt
FR2471186A1 (fr) 1979-12-10 1981-06-19 Roussel Uclaf Nouveaux comprimes a delitescence colique, ainsi que leur procede de preparation
SE8003805L (sv) 1980-05-21 1981-11-22 Haessle Ab En farmaceutisk beredning med forbettrade utlosningsegenskap
SE8008524L (sv) 1980-12-04 1982-06-05 Draco Ab 4-pregnen-derivat, ett forfarande for deras framstellning, beredning och metod for behandling av inflammatoriska tillstand
SE8306370D0 (sv) 1983-11-18 1983-11-18 Draco Ab Novel androstane-17beta-carboxylic acid esters, a process and intermediates for their preparation, compositions and method for the treatment of inflammatory conditions
US4708867A (en) 1983-12-19 1987-11-24 Key Pharmaceuticals, Inc. Minipellets
US4606940A (en) 1984-12-21 1986-08-19 The Ohio State University Research Foundation Small particle formation and encapsulation
DE3536267A1 (de) 1985-10-11 1987-04-16 Bayer Ag Azofarbstoffe sowie fluessigkristallines material enthaltend azofarbstoffe
SE8506015D0 (sv) 1985-12-19 1985-12-19 Draco Ab Novel 16,17-acetalsubstituted pregnane 21-oic acid derivatives
US4966770A (en) 1989-07-26 1990-10-30 Himedics, Inc. Prednisone microencapsulated granules
DE10307386A1 (de) 2003-02-21 2004-09-09 Dieter Wildfang Gmbh Verfahren zum außenseitigen Beschichten eines sanitären Auslaufteiles sowie sanitäres Auslaufteil

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1983000435A1 (en) * 1981-07-31 1983-02-17 Rhodes, John Orally administrable pharmaceutical compositions
EP0278174A2 (en) * 1986-12-24 1988-08-17 Glaxo Group Limited Use of fluticasone propionate in the preparation of a pharmaceutical composition for the treatment of bowel diseases

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD480Z5 (ro) * 2011-07-07 2012-09-30 Эльвира АНДОН Metodă de tratament al colitei ulceroase nespecifice acute
RU2750937C2 (ru) * 2016-02-09 2021-07-06 Альбирео Аб Пероральный состав холестирамина и его применение
RU2750944C2 (ru) * 2016-02-09 2021-07-06 Альбирео Аб Пероральный состав холестирамина и его применение

Also Published As

Publication number Publication date
AU7786491A (en) 1991-06-13
HUT60630A (en) 1992-10-28
IS3644A7 (is) 1991-05-23
HU9201700D0 (en) 1992-08-28
LTIP1751A (en) 1995-07-25
SA90110123B1 (ar) 1999-06-06
ES2074698T3 (es) 1995-09-16
YU48583B (sh) 1998-12-23
JPH05501705A (ja) 1993-04-02
SG54210A1 (en) 1998-11-16
YU215090A (sr) 1996-01-09
IE904170A1 (en) 1991-05-22
IL96415A (en) 1995-11-27
FI19991893A7 (fi) 1999-09-06
AU643021B2 (en) 1993-11-04
DE69021214D1 (de) 1995-08-31
EG19642A (en) 1995-08-30
EP0502092A1 (en) 1992-09-09
IS1858B (is) 2003-03-27
HK51897A (en) 1997-05-02
FI104949B (fi) 2000-05-15
FI922325A0 (fi) 1992-05-21
FI922325L (fi) 1992-05-21
TW250435B (https=) 1995-07-01
CA2071518A1 (en) 1991-05-23
ATE125445T1 (de) 1995-08-15
KR920703025A (ko) 1992-12-17
HU216836B (hu) 1999-09-28
PL166506B1 (pl) 1995-05-31
EP0502092B1 (en) 1995-07-26
PL287844A1 (en) 1991-12-02
FI19991893L (fi) 1999-09-06
NZ235807A (en) 1993-02-25
MY104535A (en) 1994-04-30
IL96415A0 (en) 1991-08-16
PT95946A (pt) 1991-09-13
SE8903914D0 (sv) 1989-11-22
UA37196C2 (uk) 2001-05-15
HRP920632B1 (en) 1999-10-31
GR3017691T3 (en) 1996-01-31
CA2071518C (en) 2002-11-12
IE74854B1 (en) 1997-08-13
NO922004L (no) 1992-05-21
NO922004D0 (no) 1992-05-21
LV10183B (en) 1995-08-20
ZA908777B (en) 1991-07-31
KR0179042B1 (ko) 1999-03-20
DE69021214T2 (de) 1996-01-04
NO304010B1 (no) 1998-10-12
JP3145111B2 (ja) 2001-03-12
HRP920632A2 (en) 1995-04-30
WO1991007172A1 (en) 1991-05-30
LV10183A (lv) 1994-10-20
DK0502092T3 (da) 1995-12-27
US6423340B1 (en) 2002-07-23
LT3696B (en) 1996-02-26
SI9012150A (sl) 1998-08-31

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