RU2017103679A - Способ ингибирования внутриклеточного активированного ras с помощью интакного антитела иммуноглобулинового типа, обладающего способностью к проникновению в цитозоль, и его применение - Google Patents

Способ ингибирования внутриклеточного активированного ras с помощью интакного антитела иммуноглобулинового типа, обладающего способностью к проникновению в цитозоль, и его применение Download PDF

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RU2017103679A
RU2017103679A RU2017103679A RU2017103679A RU2017103679A RU 2017103679 A RU2017103679 A RU 2017103679A RU 2017103679 A RU2017103679 A RU 2017103679A RU 2017103679 A RU2017103679 A RU 2017103679A RU 2017103679 A RU2017103679 A RU 2017103679A
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amino acid
variable region
antibody
acid sequence
cytosol
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RU2017103679A
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Russian (ru)
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Ён Сон КИМ
Тон Ки ЦОЙ
Сон Мин СИН
Сон Хун КИМ
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Орум Терапьютикс Инк.
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Priority claimed from PCT/KR2015/007627 external-priority patent/WO2016013871A1/ko
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RU2017103679A 2014-07-22 2015-07-22 Способ ингибирования внутриклеточного активированного ras с помощью интакного антитела иммуноглобулинового типа, обладающего способностью к проникновению в цитозоль, и его применение RU2017103679A (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
KR20140092687 2014-07-22
KR10-2014-0092687 2014-07-22
KR10-2015-0103214 2015-07-21
KR1020150103214A KR101602876B1 (ko) 2014-07-22 2015-07-21 완전한 이뮤노글로불린 형태의 세포질 침투능을 갖는 항체를 이용하여 세포내 활성화된 ras를 억제하는 방법 및 그의 이용
PCT/KR2015/007627 WO2016013871A1 (ko) 2014-07-22 2015-07-22 완전한 이뮤노글로불린 형태의 세포질 침투능을 갖는 항체를 이용하여 세포내 활성화된 ras를 억제하는 방법 및 그의 이용

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US (1) US10851177B2 (Direct)
EP (1) EP3173099B1 (Direct)
JP (1) JP6798988B2 (Direct)
KR (2) KR101602876B1 (Direct)
CN (1) CN106999575A (Direct)
AU (1) AU2015292956B2 (Direct)
BR (1) BR112017001306A2 (Direct)
CA (1) CA2955265A1 (Direct)
IL (1) IL250137B (Direct)
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WO2019107812A1 (ko) 2017-11-16 2019-06-06 오름테라퓨틱 주식회사 세포의 세포질에 침투하여 세포내 활성화된 ras를 억제하는 항체 및 이의 용도
KR20190143826A (ko) 2018-06-21 2019-12-31 오름테라퓨틱 주식회사 세포/조직 특이적 세포 침투 항체

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