RS62955B1 - Postupci za pripremu jedinjenja sličnih oksatiazinu - Google Patents

Postupci za pripremu jedinjenja sličnih oksatiazinu

Info

Publication number
RS62955B1
RS62955B1 RS20220195A RSP20220195A RS62955B1 RS 62955 B1 RS62955 B1 RS 62955B1 RS 20220195 A RS20220195 A RS 20220195A RS P20220195 A RSP20220195 A RS P20220195A RS 62955 B1 RS62955 B1 RS 62955B1
Authority
RS
Serbia
Prior art keywords
compound
concentrated
solution
filtered
prepared
Prior art date
Application number
RS20220195A
Other languages
English (en)
Serbian (sr)
Inventor
Rolf W Pfirrmann
Original Assignee
Geistlich Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Geistlich Pharma Ag filed Critical Geistlich Pharma Ag
Publication of RS62955B1 publication Critical patent/RS62955B1/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/02—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof
    • C07C303/04—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof by substitution of hydrogen atoms by sulfo or halosulfonyl groups
    • C07C303/12—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof by substitution of hydrogen atoms by sulfo or halosulfonyl groups by reaction with thionylhalides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/78—Halides of sulfonic acids
    • C07C309/79—Halides of sulfonic acids having halosulfonyl groups bound to acyclic carbon atoms
    • C07C309/82—Halides of sulfonic acids having halosulfonyl groups bound to acyclic carbon atoms of a carbon skeleton substituted by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/02—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof
    • C07C303/18—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof by reaction of sulfides with compounds having functional groups with formation of sulfo or halosulfonyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/02—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof
    • C07C303/22—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof from sulfonic acids, by reactions not involving the formation of sulfo or halosulfonyl groups; from sulfonic halides by reactions not involving the formation of halosulfonyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/32—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of salts of sulfonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/38—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reaction of ammonia or amines with sulfonic acids, or with esters, anhydrides, or halides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/40—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/07—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing oxygen atoms bound to the carbon skeleton
    • C07C309/09—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing oxygen atoms bound to the carbon skeleton containing etherified hydroxy groups bound to the carbon skeleton
    • C07C309/10—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing oxygen atoms bound to the carbon skeleton containing etherified hydroxy groups bound to the carbon skeleton with the oxygen atom of at least one of the etherified hydroxy groups further bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C309/07—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing oxygen atoms bound to the carbon skeleton
    • C07C309/12—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing oxygen atoms bound to the carbon skeleton containing esterified hydroxy groups bound to the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/01—Sulfonic acids
    • C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
    • C07C309/24—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of a carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
    • C07C311/23—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms
    • C07C311/24—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
    • C07C311/23—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms
    • C07C311/27—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atoms of the sulfonamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/02—1,2-Thiazines; Hydrogenated 1,2-thiazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D291/00—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms
    • C07D291/02—Heterocyclic compounds containing rings having nitrogen, oxygen and sulfur atoms as the only ring hetero atoms not condensed with other rings
    • C07D291/06—Six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D419/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
    • C07D419/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D419/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
RS20220195A 2014-12-19 2015-12-17 Postupci za pripremu jedinjenja sličnih oksatiazinu RS62955B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462094580P 2014-12-19 2014-12-19
EP15821172.2A EP3233813B1 (en) 2014-12-19 2015-12-17 Processes for preparing oxathiazin-like compounds
PCT/IB2015/059741 WO2016098054A1 (en) 2014-12-19 2015-12-17 Processes for preparing oxathiazin-like compounds

Publications (1)

Publication Number Publication Date
RS62955B1 true RS62955B1 (sr) 2022-03-31

Family

ID=55077556

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20220195A RS62955B1 (sr) 2014-12-19 2015-12-17 Postupci za pripremu jedinjenja sličnih oksatiazinu

Country Status (21)

Country Link
US (2) US10392355B2 (enExample)
EP (2) EP3233813B1 (enExample)
JP (4) JP6746605B2 (enExample)
KR (1) KR102594322B1 (enExample)
CN (3) CN107257786B (enExample)
AU (2) AU2015365348B2 (enExample)
CA (1) CA2971570A1 (enExample)
CY (1) CY1125047T1 (enExample)
DK (1) DK3233813T3 (enExample)
ES (1) ES2907592T3 (enExample)
HR (1) HRP20220313T1 (enExample)
HU (1) HUE058257T2 (enExample)
IL (1) IL252912B (enExample)
LT (1) LT3233813T (enExample)
MX (2) MX392353B (enExample)
PL (1) PL3233813T3 (enExample)
PT (1) PT3233813T (enExample)
RS (1) RS62955B1 (enExample)
SI (1) SI3233813T1 (enExample)
SM (1) SMT202200091T1 (enExample)
WO (1) WO2016098054A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11591302B2 (en) * 2014-12-19 2023-02-28 Geistlich Pharm A Ag Processes for preparing oxathiazin-like compounds
CA2971570A1 (en) * 2014-12-19 2016-06-23 Geistlich Pharma Ag Processes for preparing oxathiazin-like compounds
US10544114B2 (en) 2016-04-07 2020-01-28 Geistlich Pharma Ag Process for preparing oxathiazin-like compounds
JP7152030B2 (ja) * 2017-02-27 2022-10-12 株式会社シード探索研究所 抗真菌組成物
CN109602744A (zh) * 2018-12-13 2019-04-12 中国人民解放军总医院 荜茇酰胺在制备抗菌消炎药物中的应用
WO2020234830A1 (en) * 2019-05-22 2020-11-26 Geistlich Pharma Ag Oxathiazin_dioxide for treating, preventing, inhibiting or reducing cytokine release
WO2020234829A1 (en) * 2019-05-22 2020-11-26 Geistlich Pharma Ag Methods and compositions for inhibiting gapdh
CN114025766B (zh) * 2019-05-22 2024-09-10 盖斯特里希医药公司 用于抑制gapdh的噁噻嗪化合物
CN111671758A (zh) * 2020-07-06 2020-09-18 长春迈灵生物工程有限公司 牛磺罗定在制备抗hiv病毒药物中的应用
BR112023000308A2 (pt) * 2020-07-06 2023-03-28 Acad Of Military Medical Sciences Uso de taurolidina contra vírus
CN111617086A (zh) * 2020-07-06 2020-09-04 长春迈灵生物工程有限公司 牛磺罗定在制备抗hpv病毒药物中的应用
US20240199563A1 (en) * 2021-04-29 2024-06-20 Geistlich Pharma Ag Antimicrobial and anticancer agents
CN118724762A (zh) * 2024-06-24 2024-10-01 湖南增达生物科技有限公司 一种牛磺酸的制备新工艺

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DE1160443B (de) * 1961-11-30 1964-01-02 Hoechst Ag Verfahren zur Herstellung von Tetrahydro-oxathiazin-dioxyden
GB1124285A (en) * 1964-10-06 1968-08-21 Geistlich Soehne Ag Novel perhydro-1,2,4-thiadiazine dioxides-(1,1), their preparation and compositionscontaining them
DE1234988B (de) 1964-11-28 1967-02-23 Bayer Ag Verfahren zur Herstellung von Copolymerisaten des Trioxans
DK167393B1 (da) * 1985-12-30 1993-10-25 Roussel Uclaf 1-sulfonyl-2-oxo-pyrrolidinderivater, deres fremstilling og farmaceutiske praeparater med indhold deraf
GB8617482D0 (en) 1986-07-17 1986-08-28 Geistlich Soehne Ag Pharmaceutical composition
IT1296926B1 (it) 1997-12-05 1999-08-03 Zambon Spa Procedimento per la preparazione di composti ad attivita' antimicotica
KR101052462B1 (ko) * 2004-09-21 2011-07-28 아스텔라스세이야쿠 가부시키가이샤 아미노알콜 유도체
WO2008082725A1 (en) * 2006-12-29 2008-07-10 Anadys Pharmaceuticals, Inc. Pyridazinone compounds
JP2008222659A (ja) * 2007-03-14 2008-09-25 Asahi Kasei Corp スルホンアミド化合物の製造方法
EP2154130A4 (en) 2007-06-07 2011-09-07 Astellas Pharma Inc pyridone
US8088824B2 (en) * 2007-08-15 2012-01-03 Reata Pharmaceuticals Inc. Forms of CDDO methyl ester
US20120142676A1 (en) * 2010-08-18 2012-06-07 Gaik-Lean Chee Oxathiazine and dithiine oxides as inhibitors of sulfhydryl-dependent biomolecules
EP2643308B1 (en) * 2010-11-23 2016-08-17 Biophore India Pharmaceuticals Pvt. Ltd. Process for the preparation of taurolidine and its intermediates thereof
PL2861573T3 (pl) * 2012-06-18 2018-02-28 Geistlich Pharma Ag Pochodne oksatiazyny jako środki przeciwbakteryjne i przeciwnowotworowe
CA2971570A1 (en) * 2014-12-19 2016-06-23 Geistlich Pharma Ag Processes for preparing oxathiazin-like compounds

Also Published As

Publication number Publication date
MX2019013194A (es) 2020-01-13
MX392353B (es) 2025-03-24
BR112017013188A2 (pt) 2018-04-10
CN107257786A (zh) 2017-10-17
JP6746605B2 (ja) 2020-08-26
JP7449913B2 (ja) 2024-03-14
WO2016098054A9 (en) 2016-12-22
JP7688098B2 (ja) 2025-06-03
CN110776479A (zh) 2020-02-11
ES2907592T3 (es) 2022-04-25
KR20170113546A (ko) 2017-10-12
CN119454714A (zh) 2025-02-18
US20190389819A1 (en) 2019-12-26
EP3233813B1 (en) 2022-02-02
US20180370932A1 (en) 2018-12-27
MX369462B (es) 2019-11-08
JP2022031717A (ja) 2022-02-22
WO2016098054A1 (en) 2016-06-23
IL252912B (en) 2020-01-30
EP3233813A1 (en) 2017-10-25
LT3233813T (lt) 2022-04-11
NZ733723A (en) 2024-03-22
SI3233813T1 (sl) 2022-05-31
PL3233813T3 (pl) 2022-05-30
AU2019261702B2 (en) 2021-03-25
CY1125047T1 (el) 2023-03-24
SMT202200091T1 (it) 2022-03-21
KR102594322B1 (ko) 2023-10-26
IL252912A0 (en) 2017-08-31
HUE058257T2 (hu) 2022-07-28
JP2024028794A (ja) 2024-03-05
CN107257786B (zh) 2019-12-24
HRP20220313T1 (hr) 2022-05-13
CA2971570A1 (en) 2016-06-23
JP2018502909A (ja) 2018-02-01
DK3233813T3 (da) 2022-03-07
AU2015365348B2 (en) 2019-11-28
AU2015365348A1 (en) 2017-07-13
US10968190B2 (en) 2021-04-06
JP7030093B2 (ja) 2022-03-04
US10392355B2 (en) 2019-08-27
MX2017008112A (es) 2018-02-09
AU2019261702A1 (en) 2019-11-28
EP4011871A2 (en) 2022-06-15
PT3233813T (pt) 2022-03-14
JP2020040964A (ja) 2020-03-19
EP4011871A3 (en) 2022-08-24

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