RS59847B1 - Protein koji vezuje rgma i njegova upotreba - Google Patents

Protein koji vezuje rgma i njegova upotreba

Info

Publication number
RS59847B1
RS59847B1 RS20191502A RSP20191502A RS59847B1 RS 59847 B1 RS59847 B1 RS 59847B1 RS 20191502 A RS20191502 A RS 20191502A RS P20191502 A RSP20191502 A RS P20191502A RS 59847 B1 RS59847 B1 RS 59847B1
Authority
RS
Serbia
Prior art keywords
binding protein
rgma binding
rgma
protein
binding
Prior art date
Application number
RS20191502A
Other languages
English (en)
Inventor
Motonori Hashimoto
Toshihide Yamashita
Original Assignee
Mitsubishi Tanabe Pharma Corp
Univ Osaka
Univ Chiba Nat Univ Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Tanabe Pharma Corp, Univ Osaka, Univ Chiba Nat Univ Corp filed Critical Mitsubishi Tanabe Pharma Corp
Publication of RS59847B1 publication Critical patent/RS59847B1/sr

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94Stability, e.g. half-life, pH, temperature or enzyme-resistance
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
RS20191502A 2015-04-28 2016-04-27 Protein koji vezuje rgma i njegova upotreba RS59847B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2015091095 2015-04-28
EP16786512.0A EP3290441B1 (en) 2015-04-28 2016-04-27 Rgma binding protein and use thereof
PCT/JP2016/063166 WO2016175236A1 (ja) 2015-04-28 2016-04-27 RGMa結合タンパク質及びその使用

Publications (1)

Publication Number Publication Date
RS59847B1 true RS59847B1 (sr) 2020-02-28

Family

ID=57198582

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20191502A RS59847B1 (sr) 2015-04-28 2016-04-27 Protein koji vezuje rgma i njegova upotreba

Country Status (34)

Country Link
US (3) US10287346B2 (sr)
EP (2) EP3584260A1 (sr)
JP (6) JP6497760B2 (sr)
KR (4) KR20230173734A (sr)
CN (2) CN113801225A (sr)
AU (2) AU2016253886B2 (sr)
BR (1) BR112017022994A2 (sr)
CA (1) CA2983898A1 (sr)
CL (1) CL2017002729A1 (sr)
CO (1) CO2017011975A2 (sr)
CR (2) CR20170539A (sr)
CY (1) CY1122569T1 (sr)
DK (1) DK3290441T3 (sr)
DO (1) DOP2017000248A (sr)
ES (1) ES2758480T3 (sr)
GT (1) GT201700224A (sr)
HK (1) HK1245808A1 (sr)
HR (1) HRP20192099T1 (sr)
HU (1) HUE047146T2 (sr)
IL (2) IL287291B (sr)
LT (1) LT3290441T (sr)
MX (2) MX2017013894A (sr)
PE (2) PE20180251A1 (sr)
PH (1) PH12017501941A1 (sr)
PL (1) PL3290441T3 (sr)
PT (1) PT3290441T (sr)
RS (1) RS59847B1 (sr)
RU (1) RU2705304C2 (sr)
SA (1) SA517390230B1 (sr)
SG (1) SG11201708848TA (sr)
SI (1) SI3290441T1 (sr)
TW (3) TW202328205A (sr)
WO (1) WO2016175236A1 (sr)
ZA (2) ZA201708047B (sr)

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EP3824907A4 (en) 2018-07-19 2022-05-04 The University of Tokyo AGENT FOR THE TREATMENT OR PREVENTION OF HTLV-1 ASSOCIATED MYELOPATHY (HAM), AND METHOD OF TREATMENT OF HAM
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WO2021145435A1 (ja) 2020-01-15 2021-07-22 国立大学法人大阪大学 認知症の予防又は治療剤
CN114980929A (zh) * 2020-01-15 2022-08-30 国立大学法人大阪大学 糖尿病性自主神经障碍的预防或治疗剂
CN112138146B (zh) * 2020-09-25 2022-08-09 安徽医科大学 Manf蛋白的应用
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IL255293B (en) 2021-10-31
DK3290441T3 (da) 2020-01-02
PT3290441T (pt) 2019-12-02
JP2023030057A (ja) 2023-03-07
KR102613528B1 (ko) 2023-12-12
MX2022005565A (es) 2022-06-09
US20210277098A1 (en) 2021-09-09
CN113801225A (zh) 2021-12-17
MX2017013894A (es) 2018-03-01
TW202138389A (zh) 2021-10-16
RU2705304C2 (ru) 2019-11-06
JPWO2016175236A1 (ja) 2018-04-19
DOP2017000248A (es) 2018-01-31
SA517390230B1 (ar) 2021-06-09
US20180100012A1 (en) 2018-04-12
KR102040235B1 (ko) 2019-11-05
CA2983898A1 (en) 2016-11-03
CO2017011975A2 (es) 2018-02-20
CN107531791B (zh) 2021-09-07
PE20180251A1 (es) 2018-02-02
PH12017501941A1 (en) 2018-03-19
JP2023120374A (ja) 2023-08-29
EP3290441A4 (en) 2018-10-17
IL255293A0 (en) 2017-12-31
JP6955721B2 (ja) 2021-10-27
JP7306660B2 (ja) 2023-07-11
KR20230173734A (ko) 2023-12-27
CR20200517A (es) 2021-01-12
CR20170539A (es) 2018-04-20
HUE047146T2 (hu) 2020-04-28
AU2016253886B2 (en) 2019-05-16
ES2758480T3 (es) 2020-05-05
RU2017135353A (ru) 2019-04-08
BR112017022994A2 (pt) 2019-11-19
KR20190124350A (ko) 2019-11-04
JP7307446B2 (ja) 2023-07-12
CL2017002729A1 (es) 2018-06-08
JP2023025285A (ja) 2023-02-21
JP2019141048A (ja) 2019-08-29
KR20170138565A (ko) 2017-12-15
PE20230381A1 (es) 2023-03-06
JP2021106587A (ja) 2021-07-29
RU2019134410A (ru) 2020-03-03
IL287291A (en) 2021-12-01
PL3290441T3 (pl) 2020-05-18
US11008388B2 (en) 2021-05-18
EP3290441B1 (en) 2019-10-30
EP3290441A1 (en) 2018-03-07
TW202328205A (zh) 2023-07-16
ZA201907773B (en) 2021-05-26
HRP20192099T1 (hr) 2020-03-06
RU2017135353A3 (sr) 2019-04-08
CN107531791A (zh) 2018-01-02
KR20220140023A (ko) 2022-10-17
GT201700224A (es) 2019-07-26
EP3584260A1 (en) 2019-12-25
TWI732757B (zh) 2021-07-11
TW201710296A (zh) 2017-03-16
KR102451786B1 (ko) 2022-10-05
AU2019210655A1 (en) 2019-08-22
WO2016175236A1 (ja) 2016-11-03
US10287346B2 (en) 2019-05-14
CY1122569T1 (el) 2021-01-27
HK1245808A1 (zh) 2018-08-31
LT3290441T (lt) 2020-02-10
US20190270799A1 (en) 2019-09-05
IL287291B (en) 2022-09-01
JP6497760B2 (ja) 2019-04-10
AU2016253886A1 (en) 2017-12-14
ZA201708047B (en) 2020-01-29
SG11201708848TA (en) 2017-11-29
SI3290441T1 (sl) 2020-03-31

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