RS50859B - Formulacija rastvora za inhalaciju sa soli tiotropijuma - Google Patents

Formulacija rastvora za inhalaciju sa soli tiotropijuma

Info

Publication number
RS50859B
RS50859B YUP-330/03A YUP33003A RS50859B RS 50859 B RS50859 B RS 50859B YU P33003 A YUP33003 A YU P33003A RS 50859 B RS50859 B RS 50859B
Authority
RS
Serbia
Prior art keywords
pharmacologically acceptable
formulation containing
solution formulation
tiotropium salt
salt
Prior art date
Application number
YUP-330/03A
Other languages
English (en)
Inventor
Barbara dr. NIKLAUS-HUMKE
Christel Dr. Schmelzer
Petra Barth
Karin prof.dr. DRECHSEL
Original Assignee
Boehringer Ingelheim Pharma Gmbh. & Co.Kg.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma Gmbh. & Co.Kg. filed Critical Boehringer Ingelheim Pharma Gmbh. & Co.Kg.
Priority to MEP-2008-404A priority Critical patent/ME00244B/me
Publication of YU33003A publication Critical patent/YU33003A/sh
Publication of RS50859B publication Critical patent/RS50859B/sr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/537—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines spiro-condensed or forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)

Abstract

Farmaceutski preparat koji se sastoji od:• soli tiotropijuma kao aktivne materije, sa koncentracijom tiotropijuma izmedju 0,0005 i 5 tež. %,• vode ili smeše vode/etanola kao rastvarača za aktivnu materiju,• kiseline za podešavanje pH vrednosti izmedju 2,0 i 3,1,• farmakološki prihvatljivog konzervansa,• eventualno editinske kiseline ili so editinske kiseline u količini većoj od 0 do 25mg/100ml,• eventualno farmakološki prihvatljivog sredstva za obrazovanje kompleksa i/ili stabilizatora ili farmakološki prihvatljivog kosolventa i/ili drugih farmakološki prihvatljivih pomoćnih i dodatnih materija osim konzervansa.Prijava sadrži još 18 patentnih zahteva.
YUP-330/03A 2000-10-31 2001-10-24 Formulacija rastvora za inhalaciju sa soli tiotropijuma RS50859B (sr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MEP-2008-404A ME00244B (me) 2000-10-31 2001-10-24 Formulacija rastvora za inhalaciju sa soli tiotropijma

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10054036 2000-10-31

Publications (2)

Publication Number Publication Date
YU33003A YU33003A (sh) 2006-05-25
RS50859B true RS50859B (sr) 2010-08-31

Family

ID=7661723

Family Applications (1)

Application Number Title Priority Date Filing Date
YUP-330/03A RS50859B (sr) 2000-10-31 2001-10-24 Formulacija rastvora za inhalaciju sa soli tiotropijuma

Country Status (39)

Country Link
EP (2) EP1333819B1 (sr)
JP (1) JP4344135B2 (sr)
KR (1) KR100853107B1 (sr)
CN (2) CN101292964A (sr)
AR (1) AR038764A1 (sr)
AT (1) ATE373473T1 (sr)
AU (2) AU2173802A (sr)
BG (1) BG66315B1 (sr)
BR (1) BRPI0115076B8 (sr)
CA (1) CA2426074C (sr)
CY (1) CY1107825T1 (sr)
CZ (1) CZ300794B6 (sr)
DE (2) DE50113037D1 (sr)
DK (1) DK1333819T3 (sr)
EA (1) EA007604B1 (sr)
EC (1) ECSP034541A (sr)
EE (1) EE05314B1 (sr)
ES (1) ES2294045T3 (sr)
HK (1) HK1060524A1 (sr)
HR (1) HRP20030338B1 (sr)
HU (1) HU229411B1 (sr)
IL (2) IL155538A0 (sr)
ME (1) ME00244B (sr)
MX (1) MXPA03003742A (sr)
MY (1) MY138940A (sr)
NO (1) NO332519B1 (sr)
NZ (1) NZ526023A (sr)
PE (1) PE20030092A1 (sr)
PL (1) PL203316B1 (sr)
PT (1) PT1333819E (sr)
RS (1) RS50859B (sr)
SA (1) SA01220482B1 (sr)
SI (1) SI1333819T1 (sr)
SK (1) SK286027B6 (sr)
TW (1) TWI293885B (sr)
UA (1) UA78690C2 (sr)
UY (1) UY26989A1 (sr)
WO (1) WO2002036104A2 (sr)
ZA (1) ZA200302922B (sr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10216036A1 (de) * 2002-04-11 2003-10-23 Boehringer Ingelheim Pharma Aerosolformulierung für die Inhalation enthaltend ein Tiotropiumsalz
CN1292748C (zh) * 2003-03-05 2007-01-03 南昌弘益科技有限公司 噻托溴铵吸入粉雾剂及其制备工艺
SI2067779T1 (sl) * 2003-11-03 2013-08-30 Boehringer Ingelheim International Gmbh Tiotropijeve soli, postopek za njihovo pripravo in formulacije zdravil, ki jih vsebujejo
RS20060293A (en) * 2003-11-03 2008-08-07 Boehringer Ingelheim International Gmbh., Novel tiotropium salts, methods for the production thereof, and pharmaceutical formulations containing the same
DK1881980T3 (da) 2005-05-02 2012-10-01 Boehringer Ingelheim Int Nye krystalline former af tiotropiumbromid
EP2044967A1 (de) * 2007-10-01 2009-04-08 Boehringer Ingelheim Pharma GmbH & Co. KG Zerstäuber
CN104306361A (zh) * 2014-09-24 2015-01-28 万特制药(海南)有限公司 一种含噻托溴铵的吸入性溶液
CN111374963A (zh) * 2018-12-31 2020-07-07 天津药业研究院有限公司 一种用于吸入的噻托铵溶液剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3931041C2 (de) * 1989-09-16 2000-04-06 Boehringer Ingelheim Kg Ester von Thienylcarbonsäuren mit Aminoalkoholen, ihre Quaternierungsprodukte, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
SG45171A1 (en) * 1990-03-21 1998-01-16 Boehringer Ingelheim Int Atomising devices and methods
DE19536902A1 (de) * 1995-10-04 1997-04-10 Boehringer Ingelheim Int Vorrichtung zur Hochdruckerzeugung in einem Fluid in Miniaturausführung
DE19653969A1 (de) * 1996-12-20 1998-06-25 Boehringer Ingelheim Kg Neue wässrige Arzneimittelzubereitung zur Erzeugung treibgasfreier Aerosole
DE19847968A1 (de) * 1998-10-17 2000-04-20 Boehringer Ingelheim Pharma Verschlußkappe und Behälter als Zweikammer-Kartusche für Vernebler zur Erzeugung von Aerosolen

Also Published As

Publication number Publication date
DK1333819T3 (da) 2007-12-03
ECSP034541A (es) 2003-05-26
ME00244B (me) 2011-05-10
EA200300482A1 (ru) 2003-12-25
HUP0301378A3 (en) 2005-12-28
EP1837021A2 (de) 2007-09-26
BR0115076A (pt) 2003-07-29
SI1333819T1 (sl) 2007-12-31
PL203316B1 (pl) 2009-09-30
HRP20030338A2 (en) 2005-04-30
EE200300203A (et) 2003-10-15
HRP20030338B1 (en) 2011-09-30
HU229411B1 (en) 2013-12-30
CZ300794B6 (cs) 2009-08-12
NO332519B1 (no) 2012-10-08
WO2002036104A3 (de) 2002-08-01
MXPA03003742A (es) 2004-10-15
KR100853107B1 (ko) 2008-08-21
MEP40408A (en) 2011-02-10
CZ20031486A3 (cs) 2003-08-13
IL155538A (en) 2008-11-26
EP1333819B1 (de) 2007-09-19
EA007604B1 (ru) 2006-12-29
NO20031911D0 (no) 2003-04-29
KR20030060926A (ko) 2003-07-16
NO20031911L (no) 2003-04-29
HK1060524A1 (en) 2004-08-13
WO2002036104A2 (de) 2002-05-10
DE50113037D1 (de) 2007-10-31
DE10152521A1 (de) 2002-07-11
SK5272003A3 (en) 2003-10-07
BG66315B1 (bg) 2013-04-30
CY1107825T1 (el) 2013-06-19
AU2173802A (en) 2002-05-15
EE05314B1 (et) 2010-08-16
EP1333819A2 (de) 2003-08-13
CA2426074A1 (en) 2002-05-10
JP4344135B2 (ja) 2009-10-14
IL155538A0 (en) 2003-11-23
NZ526023A (en) 2005-05-27
PE20030092A1 (es) 2003-03-24
UA78690C2 (uk) 2007-04-25
CN1473038A (zh) 2004-02-04
BRPI0115076B1 (pt) 2016-07-26
JP2004512357A (ja) 2004-04-22
MY138940A (en) 2009-08-28
ZA200302922B (en) 2004-04-22
CN101292964A (zh) 2008-10-29
SK286027B6 (sk) 2008-01-07
PL360405A1 (en) 2004-09-06
CN100396285C (zh) 2008-06-25
AU2002221738B2 (en) 2007-01-11
ATE373473T1 (de) 2007-10-15
UY26989A1 (es) 2002-06-20
SA01220482B1 (ar) 2007-07-31
BG107727A (bg) 2004-11-30
PT1333819E (pt) 2007-10-29
TWI293885B (en) 2008-03-01
YU33003A (sh) 2006-05-25
BRPI0115076B8 (pt) 2021-05-25
AR038764A1 (es) 2005-01-26
EP1837021A3 (de) 2008-03-19
ES2294045T3 (es) 2008-04-01
CA2426074C (en) 2008-12-23
HUP0301378A2 (hu) 2003-10-28

Similar Documents

Publication Publication Date Title
KR100621817B1 (ko) 비스테로이드성 소염(nsai) 약물을 포함하는 국소 투여용 수성 약제학적 조성물
CA2232855C (en) Pharmaceutical formulation
KR860001801B1 (ko) 국소용 소염조성물의 제조방법
BG106439A (en) Pharmaceutical composition of improved solubility and oral absorptivity, containing benzamide derivative
RU2010123282A (ru) Твердая лекарственная форма с быстрым высвобождением активного вещества, ее получение и применение
CA2673976C (en) Gel composition for treating mycosis
RS51934B (sr) Tableta bupropion hidrohlorida sa modifikovanim otpuštanjem
WO2006053646A3 (en) Improvements in or relating to pharmaceutical compositions for local administration
JP2009511553A (ja) 爪および爪周辺への塗布のためのアモロルフィンおよび水溶性皮膜形成剤に基づく医薬組成物
JP4393552B2 (ja) ピリドンカルボン酸誘導体を含有するローション剤
RS50173B (sr) Upotreba epinastina za lečenje alergijskog rinitisa/konjuktivitisa
RS50859B (sr) Formulacija rastvora za inhalaciju sa soli tiotropijuma
AR082049A1 (es) Formulaciones liquidas de rupatadina fumarato
KR100878198B1 (ko) 미녹시딜을 포함하는 겔 조성물
KR20190075956A (ko) 에피나스틴 함유 점안액
RU2005126279A (ru) Комплексный способ профилактики вагинальных дисбактериозов (варианты)
NO20055601L (no) Farmasoytisk preparat i form av en hydrogel for transdermal administrasjon av aktive virkestoffer
RS52966B (sr) Oblik za terapijsku primenu aktivnih peptida sa produženim oslobađanjem aktivnog sastojka i postupak za njihovo dobijanje
JP2013514333A (ja) 爪に適用することができる抗真菌溶液の調製のためのカチオン性、有利には両性界面活性剤の使用
BR0116060A (pt) Composição farmacêutica de dronedarona para administração parenteral
WO2001051028A3 (en) Formulations and methods for administration of pharmacologically or biologically active compounds
HRP20020181B1 (hr) Farmaceutski pripravci koji sadrže derivat benzamida kao aktivan sastojak
HUP0301377A2 (hu) Tiotropiumsót tartalmazó inhalációs oldatformájú kombinációs gyógyszerkészítmény
JP2003517462A5 (sr)
JPH0717863A (ja) プラノプロフェン点眼液