MY138940A - Inhalable formulation of a solution containing a tiotropium salt. - Google Patents

Inhalable formulation of a solution containing a tiotropium salt.

Info

Publication number
MY138940A
MY138940A MYPI20015000A MYPI20015000A MY138940A MY 138940 A MY138940 A MY 138940A MY PI20015000 A MYPI20015000 A MY PI20015000A MY PI20015000 A MYPI20015000 A MY PI20015000A MY 138940 A MY138940 A MY 138940A
Authority
MY
Malaysia
Prior art keywords
solution containing
inhalable formulation
tiotropium salt
propellant
water
Prior art date
Application number
MYPI20015000A
Inventor
Karin Dr Drechsel
Barbara Dr Niklaus-Humke
Christel Dr Schmelzer
Petra Barth
Original Assignee
Boehringer Inghelheim Pharma Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Inghelheim Pharma Gmbh & Co Kg filed Critical Boehringer Inghelheim Pharma Gmbh & Co Kg
Publication of MY138940A publication Critical patent/MY138940A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/537—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines spiro-condensed or forming part of bridged ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

THE PRESENT INVENTION RELATES TO A PROPELLANT-FREE INHALABLE FORMULATION OF TIOTROPIUM BROMIDE OR TIOTROPIUM BROMIDE MONOHYDRATE DISSOLVED IN WATER OR IN A MIXTURE OF WATER AND ETHANOL AND PROPELLANT-FREE INHALABLE AEROSOLS RESULTING THEREFROM.
MYPI20015000A 2000-10-31 2001-10-29 Inhalable formulation of a solution containing a tiotropium salt. MY138940A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10054036 2000-10-31

Publications (1)

Publication Number Publication Date
MY138940A true MY138940A (en) 2009-08-28

Family

ID=7661723

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI20015000A MY138940A (en) 2000-10-31 2001-10-29 Inhalable formulation of a solution containing a tiotropium salt.

Country Status (39)

Country Link
EP (2) EP1837021A3 (en)
JP (1) JP4344135B2 (en)
KR (1) KR100853107B1 (en)
CN (2) CN101292964A (en)
AR (1) AR038764A1 (en)
AT (1) ATE373473T1 (en)
AU (2) AU2002221738B2 (en)
BG (1) BG66315B1 (en)
BR (1) BRPI0115076B8 (en)
CA (1) CA2426074C (en)
CY (1) CY1107825T1 (en)
CZ (1) CZ300794B6 (en)
DE (2) DE50113037D1 (en)
DK (1) DK1333819T3 (en)
EA (1) EA007604B1 (en)
EC (1) ECSP034541A (en)
EE (1) EE05314B1 (en)
ES (1) ES2294045T3 (en)
HK (1) HK1060524A1 (en)
HR (1) HRP20030338B1 (en)
HU (1) HU229411B1 (en)
IL (2) IL155538A0 (en)
ME (1) ME00244B (en)
MX (1) MXPA03003742A (en)
MY (1) MY138940A (en)
NO (1) NO332519B1 (en)
NZ (1) NZ526023A (en)
PE (1) PE20030092A1 (en)
PL (1) PL203316B1 (en)
PT (1) PT1333819E (en)
RS (1) RS50859B (en)
SA (1) SA01220482B1 (en)
SI (1) SI1333819T1 (en)
SK (1) SK286027B6 (en)
TW (1) TWI293885B (en)
UA (1) UA78690C2 (en)
UY (1) UY26989A1 (en)
WO (1) WO2002036104A2 (en)
ZA (1) ZA200302922B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10216036A1 (en) * 2002-04-11 2003-10-23 Boehringer Ingelheim Pharma Aerosol formulation for inhalation containing a tiotropium salt
CN1292748C (en) * 2003-03-05 2007-01-03 南昌弘益科技有限公司 Timepidium bromide inhalant powders and their preparing process
WO2005042528A1 (en) * 2003-11-03 2005-05-12 Boehringer Ingelheim International Gmbh Novel tiotropium salts, methods for the production thereof, and pharmaceutical formulations containing the same
JP5165244B2 (en) * 2003-11-03 2013-03-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Method for producing tiotropium salt, tiotropium salt and pharmaceutical composition containing the same
NZ563596A (en) 2005-05-02 2011-01-28 Boehringer Ingelheim Int Crystalline form of tiotropium bromide anhydrate
EP2044967A1 (en) * 2007-10-01 2009-04-08 Boehringer Ingelheim Pharma GmbH & Co. KG Atomiser
CN104306361A (en) * 2014-09-24 2015-01-28 万特制药(海南)有限公司 Tiotropium bromide-containing inhalable solution
CN111374963A (en) * 2018-12-31 2020-07-07 天津药业研究院有限公司 Tiotropium solution for inhalation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3931041C2 (en) * 1989-09-16 2000-04-06 Boehringer Ingelheim Kg Esters of thienyl carboxylic acids with amino alcohols, their quaternization products, processes for their preparation and medicaments containing them
SG45171A1 (en) * 1990-03-21 1998-01-16 Boehringer Ingelheim Int Atomising devices and methods
DE19536902A1 (en) * 1995-10-04 1997-04-10 Boehringer Ingelheim Int Miniature fluid pressure generating device
DE19653969A1 (en) * 1996-12-20 1998-06-25 Boehringer Ingelheim Kg New aqueous pharmaceutical preparation for the production of propellant-free aerosols
DE19847968A1 (en) * 1998-10-17 2000-04-20 Boehringer Ingelheim Pharma Separate storage of an active material and a solvent comprises a closure cap and a container, with a chamber attached to the unit.

Also Published As

Publication number Publication date
EA200300482A1 (en) 2003-12-25
MXPA03003742A (en) 2004-10-15
ECSP034541A (en) 2003-05-26
JP4344135B2 (en) 2009-10-14
BG107727A (en) 2004-11-30
NZ526023A (en) 2005-05-27
EE200300203A (en) 2003-10-15
AU2002221738B2 (en) 2007-01-11
NO20031911L (en) 2003-04-29
EP1333819A2 (en) 2003-08-13
TWI293885B (en) 2008-03-01
IL155538A0 (en) 2003-11-23
UY26989A1 (en) 2002-06-20
HUP0301378A3 (en) 2005-12-28
PT1333819E (en) 2007-10-29
CN101292964A (en) 2008-10-29
WO2002036104A2 (en) 2002-05-10
DE10152521A1 (en) 2002-07-11
CZ20031486A3 (en) 2003-08-13
PL360405A1 (en) 2004-09-06
MEP40408A (en) 2011-02-10
AR038764A1 (en) 2005-01-26
ME00244B (en) 2011-05-10
AU2173802A (en) 2002-05-15
SI1333819T1 (en) 2007-12-31
BRPI0115076B8 (en) 2021-05-25
SK5272003A3 (en) 2003-10-07
BR0115076A (en) 2003-07-29
CA2426074C (en) 2008-12-23
DK1333819T3 (en) 2007-12-03
CA2426074A1 (en) 2002-05-10
ES2294045T3 (en) 2008-04-01
HU229411B1 (en) 2013-12-30
DE50113037D1 (en) 2007-10-31
YU33003A (en) 2006-05-25
CN100396285C (en) 2008-06-25
PL203316B1 (en) 2009-09-30
RS50859B (en) 2010-08-31
IL155538A (en) 2008-11-26
HUP0301378A2 (en) 2003-10-28
SK286027B6 (en) 2008-01-07
EP1333819B1 (en) 2007-09-19
CY1107825T1 (en) 2013-06-19
EA007604B1 (en) 2006-12-29
CZ300794B6 (en) 2009-08-12
BRPI0115076B1 (en) 2016-07-26
HRP20030338B1 (en) 2011-09-30
JP2004512357A (en) 2004-04-22
KR100853107B1 (en) 2008-08-21
HK1060524A1 (en) 2004-08-13
EP1837021A3 (en) 2008-03-19
ATE373473T1 (en) 2007-10-15
NO332519B1 (en) 2012-10-08
EP1837021A2 (en) 2007-09-26
HRP20030338A2 (en) 2005-04-30
SA01220482B1 (en) 2007-07-31
KR20030060926A (en) 2003-07-16
CN1473038A (en) 2004-02-04
NO20031911D0 (en) 2003-04-29
UA78690C2 (en) 2007-04-25
EE05314B1 (en) 2010-08-16
BG66315B1 (en) 2013-04-30
ZA200302922B (en) 2004-04-22
PE20030092A1 (en) 2003-03-24
WO2002036104A3 (en) 2002-08-01

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