HK1060524A1 - Inhalative solution formulation containing a tiotropium salt - Google Patents

Inhalative solution formulation containing a tiotropium salt

Info

Publication number
HK1060524A1
HK1060524A1 HK04103586A HK04103586A HK1060524A1 HK 1060524 A1 HK1060524 A1 HK 1060524A1 HK 04103586 A HK04103586 A HK 04103586A HK 04103586 A HK04103586 A HK 04103586A HK 1060524 A1 HK1060524 A1 HK 1060524A1
Authority
HK
Hong Kong
Prior art keywords
formulation containing
solution formulation
tiotropium salt
inhalative solution
inhalative
Prior art date
Application number
HK04103586A
Inventor
Barbara Niklaus-Humke
Christel Schmelzer
Petra Barth
Karin Drechsel
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of HK1060524A1 publication Critical patent/HK1060524A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/468-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/537Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines spiro-condensed or forming part of bridged ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
HK04103586A 2000-10-31 2004-05-20 Inhalative solution formulation containing a tiotropium salt HK1060524A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10054036 2000-10-31
PCT/EP2001/012292 WO2002036104A2 (en) 2000-10-31 2001-10-24 Inhalative solution formulation containing a tiotropium salt

Publications (1)

Publication Number Publication Date
HK1060524A1 true HK1060524A1 (en) 2004-08-13

Family

ID=7661723

Family Applications (1)

Application Number Title Priority Date Filing Date
HK04103586A HK1060524A1 (en) 2000-10-31 2004-05-20 Inhalative solution formulation containing a tiotropium salt

Country Status (39)

Country Link
EP (2) EP1333819B1 (en)
JP (1) JP4344135B2 (en)
KR (1) KR100853107B1 (en)
CN (2) CN101292964A (en)
AR (1) AR038764A1 (en)
AT (1) ATE373473T1 (en)
AU (2) AU2173802A (en)
BG (1) BG66315B1 (en)
BR (1) BRPI0115076B8 (en)
CA (1) CA2426074C (en)
CY (1) CY1107825T1 (en)
CZ (1) CZ300794B6 (en)
DE (2) DE50113037D1 (en)
DK (1) DK1333819T3 (en)
EA (1) EA007604B1 (en)
EC (1) ECSP034541A (en)
EE (1) EE05314B1 (en)
ES (1) ES2294045T3 (en)
HK (1) HK1060524A1 (en)
HR (1) HRP20030338B1 (en)
HU (1) HU229411B1 (en)
IL (2) IL155538A0 (en)
ME (1) ME00244B (en)
MX (1) MXPA03003742A (en)
MY (1) MY138940A (en)
NO (1) NO332519B1 (en)
NZ (1) NZ526023A (en)
PE (1) PE20030092A1 (en)
PL (1) PL203316B1 (en)
PT (1) PT1333819E (en)
RS (1) RS50859B (en)
SA (1) SA01220482B1 (en)
SI (1) SI1333819T1 (en)
SK (1) SK286027B6 (en)
TW (1) TWI293885B (en)
UA (1) UA78690C2 (en)
UY (1) UY26989A1 (en)
WO (1) WO2002036104A2 (en)
ZA (1) ZA200302922B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10216036A1 (en) * 2002-04-11 2003-10-23 Boehringer Ingelheim Pharma Aerosol formulation for inhalation containing a tiotropium salt
CN1292748C (en) * 2003-03-05 2007-01-03 南昌弘益科技有限公司 Timepidium bromide inhalant powders and their preparing process
WO2005042526A1 (en) * 2003-11-03 2005-05-12 Boehringer Ingelheim International Gmbh Method for producing tiotropium salts, tiotropium salts and pharmaceutical formulations, containing the same
CN1875020B (en) * 2003-11-03 2010-04-28 贝林格尔.英格海姆国际有限公司 Novel tiotropium salts, methods for the production thereof, and pharmaceutical formulations containing the same
CA2606549A1 (en) 2005-05-02 2006-11-09 Boehringer Ingelheim International Gmbh Crystalline forms of tiotropium bromide
EP2044967A1 (en) * 2007-10-01 2009-04-08 Boehringer Ingelheim Pharma GmbH & Co. KG Atomiser
CN104306361A (en) * 2014-09-24 2015-01-28 万特制药(海南)有限公司 Tiotropium bromide-containing inhalable solution
CN111374963A (en) * 2018-12-31 2020-07-07 天津药业研究院有限公司 Tiotropium solution for inhalation

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3931041C2 (en) * 1989-09-16 2000-04-06 Boehringer Ingelheim Kg Esters of thienyl carboxylic acids with amino alcohols, their quaternization products, processes for their preparation and medicaments containing them
SG45171A1 (en) * 1990-03-21 1998-01-16 Boehringer Ingelheim Int Atomising devices and methods
DE19536902A1 (en) * 1995-10-04 1997-04-10 Boehringer Ingelheim Int Miniature fluid pressure generating device
DE19653969A1 (en) * 1996-12-20 1998-06-25 Boehringer Ingelheim Kg New aqueous pharmaceutical preparation for the production of propellant-free aerosols
DE19847968A1 (en) * 1998-10-17 2000-04-20 Boehringer Ingelheim Pharma Separate storage of an active material and a solvent comprises a closure cap and a container, with a chamber attached to the unit.

Also Published As

Publication number Publication date
HU229411B1 (en) 2013-12-30
NO332519B1 (en) 2012-10-08
ZA200302922B (en) 2004-04-22
NZ526023A (en) 2005-05-27
NO20031911L (en) 2003-04-29
PE20030092A1 (en) 2003-03-24
WO2002036104A2 (en) 2002-05-10
ECSP034541A (en) 2003-05-26
TWI293885B (en) 2008-03-01
HRP20030338B1 (en) 2011-09-30
AR038764A1 (en) 2005-01-26
EA200300482A1 (en) 2003-12-25
IL155538A (en) 2008-11-26
MEP40408A (en) 2011-02-10
JP4344135B2 (en) 2009-10-14
BG66315B1 (en) 2013-04-30
SA01220482B1 (en) 2007-07-31
WO2002036104A3 (en) 2002-08-01
JP2004512357A (en) 2004-04-22
CA2426074A1 (en) 2002-05-10
AU2173802A (en) 2002-05-15
UA78690C2 (en) 2007-04-25
CZ20031486A3 (en) 2003-08-13
CZ300794B6 (en) 2009-08-12
CN101292964A (en) 2008-10-29
PL360405A1 (en) 2004-09-06
SK286027B6 (en) 2008-01-07
ATE373473T1 (en) 2007-10-15
HUP0301378A3 (en) 2005-12-28
EP1333819A2 (en) 2003-08-13
SK5272003A3 (en) 2003-10-07
CN100396285C (en) 2008-06-25
ES2294045T3 (en) 2008-04-01
KR20030060926A (en) 2003-07-16
KR100853107B1 (en) 2008-08-21
PT1333819E (en) 2007-10-29
YU33003A (en) 2006-05-25
SI1333819T1 (en) 2007-12-31
BRPI0115076B1 (en) 2016-07-26
BR0115076A (en) 2003-07-29
HUP0301378A2 (en) 2003-10-28
EP1837021A2 (en) 2007-09-26
EP1333819B1 (en) 2007-09-19
HRP20030338A2 (en) 2005-04-30
EP1837021A3 (en) 2008-03-19
RS50859B (en) 2010-08-31
DE50113037D1 (en) 2007-10-31
MXPA03003742A (en) 2004-10-15
EE200300203A (en) 2003-10-15
EA007604B1 (en) 2006-12-29
EE05314B1 (en) 2010-08-16
AU2002221738B2 (en) 2007-01-11
MY138940A (en) 2009-08-28
PL203316B1 (en) 2009-09-30
DE10152521A1 (en) 2002-07-11
UY26989A1 (en) 2002-06-20
DK1333819T3 (en) 2007-12-03
IL155538A0 (en) 2003-11-23
BRPI0115076B8 (en) 2021-05-25
BG107727A (en) 2004-11-30
CA2426074C (en) 2008-12-23
NO20031911D0 (en) 2003-04-29
CN1473038A (en) 2004-02-04
ME00244B (en) 2011-05-10
CY1107825T1 (en) 2013-06-19

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PE Patent expired

Effective date: 20211023