PT96681A - Processo para a preparacao de aminas triciclicas-ciclicas uteis como inibidores da colinesterase - Google Patents
Processo para a preparacao de aminas triciclicas-ciclicas uteis como inibidores da colinesterase Download PDFInfo
- Publication number
- PT96681A PT96681A PT96681A PT9668191A PT96681A PT 96681 A PT96681 A PT 96681A PT 96681 A PT96681 A PT 96681A PT 9668191 A PT9668191 A PT 9668191A PT 96681 A PT96681 A PT 96681A
- Authority
- PT
- Portugal
- Prior art keywords
- formula
- compound
- carbon
- quot
- nitrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47692890A | 1990-02-08 | 1990-02-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT96681A true PT96681A (pt) | 1991-10-31 |
Family
ID=23893824
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT96681A PT96681A (pt) | 1990-02-08 | 1991-02-06 | Processo para a preparacao de aminas triciclicas-ciclicas uteis como inibidores da colinesterase |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0441517A3 (en, 2012) |
| JP (1) | JPH07119214B2 (en, 2012) |
| KR (1) | KR950013562B1 (en, 2012) |
| CN (1) | CN1054600A (en, 2012) |
| AU (1) | AU631723B2 (en, 2012) |
| BR (1) | BR9100519A (en, 2012) |
| CA (1) | CA2035805C (en, 2012) |
| CS (1) | CS29991A2 (en, 2012) |
| DE (1) | DE9101348U1 (en, 2012) |
| EG (1) | EG19644A (en, 2012) |
| FI (1) | FI910592A7 (en, 2012) |
| HU (1) | HUT70051A (en, 2012) |
| IE (1) | IE910402A1 (en, 2012) |
| IL (1) | IL97140A (en, 2012) |
| NO (1) | NO177534C (en, 2012) |
| NZ (1) | NZ237040A (en, 2012) |
| PL (2) | PL167078B1 (en, 2012) |
| PT (1) | PT96681A (en, 2012) |
| TW (1) | TW197442B (en, 2012) |
| YU (1) | YU21391A (en, 2012) |
| ZA (1) | ZA91916B (en, 2012) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2807577B2 (ja) * | 1990-06-15 | 1998-10-08 | エーザイ株式会社 | 環状アミド誘導体 |
| EP0475908A1 (de) * | 1990-09-14 | 1992-03-18 | Ciba-Geigy Ag | Chromogene Lactamverbindungen und ihre Herstellung und Verwendung |
| TW263504B (en, 2012) * | 1991-10-03 | 1995-11-21 | Pfizer | |
| TW248556B (en, 2012) * | 1993-01-18 | 1995-06-01 | Takeda Pharm Industry Co | |
| US5620973A (en) * | 1993-11-30 | 1997-04-15 | Takeda Chemical Industries, Ltd. | Tetracyclic condensed heterocyclic compounds and their use |
| EP1118322A4 (en) | 1998-09-30 | 2004-10-20 | Takeda Chemical Industries Ltd | MEDICINES THAT IMPROVE BLADDER DRAINING POWER |
| PL376440A1 (en) * | 2002-10-30 | 2005-12-27 | Merck Frosst Canada Ltd. | Pyridopyrrolizine and pyridoindolizine derivatives |
| US7662831B2 (en) | 2006-07-27 | 2010-02-16 | Wyeth Llc | Tetracyclic indoles as potassium channel modulators |
| US7601856B2 (en) | 2006-07-27 | 2009-10-13 | Wyeth | Benzofurans as potassium ion channel modulators |
| WO2012038966A1 (en) | 2010-09-22 | 2012-03-29 | Tyche Industries Ltd. | Process for the preparation of donepezil intermediate |
| HUE056791T2 (hu) * | 2017-09-07 | 2022-03-28 | Eisai R&D Man Co Ltd | Pentaciklusos vegyület |
| PE20211978A1 (es) | 2019-03-05 | 2021-10-05 | Eisai Randd Man Co Ltd | Compuesto heterociclo pentaciclico |
| TWI870286B (zh) * | 2019-03-05 | 2025-01-11 | 日商衛材R&D企管股份有限公司 | 五環化合物之鹽及其等之結晶 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3910947A (en) * | 1969-07-24 | 1975-10-07 | Sandoz Ag | Preparation of imidazo{8 2,1-a{9 isoindoles |
| IT1199076B (it) * | 1984-03-01 | 1988-12-30 | Consiglio Nazionale Ricerche | Derivati della fisostigmina con proprieta'di inibizione della aceticolinesterasi e relativo procedimento di produzione |
| US4563469A (en) * | 1984-07-20 | 1986-01-07 | Warner-Lambert Company | Derivatives of N-[2-(tetrahydro-3,5-dioxo-1H-pyrrolizin-7a(5H)-yl)ethyl]amine as cognition activators |
| EP0187619A3 (de) * | 1985-01-03 | 1987-08-26 | Ciba-Geigy Ag | 1,3-disubstituierte Tetrahydropyridine |
| US4791107A (en) * | 1986-07-16 | 1988-12-13 | Hoechst-Roussel Pharmaceuticals, Inc. | Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use |
| US4778812A (en) * | 1987-06-12 | 1988-10-18 | American Home Products Corporation | 2,3-dihydro-9-methyl-1H-pyrrolo[1,2-a]indol-1-amines and derivatives thereof |
| EP0351283A1 (fr) * | 1988-07-12 | 1990-01-17 | Synthelabo | Dérivés de [(pipéridinyl-4) méthyl]-2 dihydro-2,3 1H-isoindole et tétrahydro-2,3,4,5 1H-benzazépines, leur préparation et leur application en thérapeutique |
-
1991
- 1991-01-23 TW TW080100556A patent/TW197442B/zh active
- 1991-01-29 EP EP19910300662 patent/EP0441517A3/en not_active Withdrawn
- 1991-02-03 IL IL9714091A patent/IL97140A/en not_active IP Right Cessation
- 1991-02-06 CA CA002035805A patent/CA2035805C/en not_active Expired - Fee Related
- 1991-02-06 PL PL91304632A patent/PL167078B1/pl unknown
- 1991-02-06 DE DE9101348U patent/DE9101348U1/de not_active Expired - Lifetime
- 1991-02-06 PL PL91288977A patent/PL166757B1/pl unknown
- 1991-02-06 PT PT96681A patent/PT96681A/pt unknown
- 1991-02-07 KR KR1019910002113A patent/KR950013562B1/ko not_active Expired - Lifetime
- 1991-02-07 FI FI910592A patent/FI910592A7/fi not_active Application Discontinuation
- 1991-02-07 IE IE040291A patent/IE910402A1/en unknown
- 1991-02-07 NO NO910473A patent/NO177534C/no unknown
- 1991-02-07 AU AU70879/91A patent/AU631723B2/en not_active Ceased
- 1991-02-07 CN CN91100860A patent/CN1054600A/zh active Pending
- 1991-02-07 YU YU21391A patent/YU21391A/sh unknown
- 1991-02-07 CS CS91299A patent/CS29991A2/cs unknown
- 1991-02-07 HU HU91406A patent/HUT70051A/hu unknown
- 1991-02-07 ZA ZA91916A patent/ZA91916B/xx unknown
- 1991-02-07 BR BR919100519A patent/BR9100519A/pt not_active Application Discontinuation
- 1991-02-07 NZ NZ237040A patent/NZ237040A/xx unknown
- 1991-02-07 EG EG7591A patent/EG19644A/xx active
- 1991-02-08 JP JP3103992A patent/JPH07119214B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| NZ237040A (en) | 1993-10-26 |
| KR950013562B1 (ko) | 1995-11-09 |
| CS29991A2 (en) | 1991-09-15 |
| ZA91916B (en) | 1992-09-30 |
| FI910592A0 (fi) | 1991-02-07 |
| EP0441517A2 (en) | 1991-08-14 |
| CN1054600A (zh) | 1991-09-18 |
| JPH07119214B2 (ja) | 1995-12-20 |
| HU910406D0 (en) | 1991-08-28 |
| HUT70051A (en) | 1995-09-28 |
| NO177534B (no) | 1995-06-26 |
| NO177534C (no) | 1995-10-04 |
| IL97140A0 (en) | 1992-05-25 |
| PL166757B1 (pl) | 1995-06-30 |
| FI910592L (fi) | 1991-08-09 |
| IL97140A (en) | 1995-07-31 |
| DE9101348U1 (de) | 1991-06-06 |
| BR9100519A (pt) | 1991-10-29 |
| NO910473L (no) | 1991-08-09 |
| JPH04234845A (ja) | 1992-08-24 |
| AU631723B2 (en) | 1992-12-03 |
| EP0441517A3 (en) | 1992-08-19 |
| FI910592A7 (fi) | 1991-08-09 |
| YU21391A (sh) | 1994-01-20 |
| EG19644A (en) | 1995-08-30 |
| TW197442B (en, 2012) | 1993-01-01 |
| PL167078B1 (pl) | 1995-07-31 |
| AU7087991A (en) | 1991-08-29 |
| IE910402A1 (en) | 1991-08-14 |
| KR910015580A (ko) | 1991-09-30 |
| CA2035805C (en) | 1995-06-27 |
| NO910473D0 (no) | 1991-02-07 |
| PL288977A1 (en) | 1992-01-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB1A | Laying open of patent application |
Effective date: 19910702 |