BR9100519A - Composto,composicao farmaceutica,metodo para inibicao de colinesterase em um mamifero e metodo para melhorar a memoria ou tratar ou prevenir a doenca de alzheimer - Google Patents
Composto,composicao farmaceutica,metodo para inibicao de colinesterase em um mamifero e metodo para melhorar a memoria ou tratar ou prevenir a doenca de alzheimerInfo
- Publication number
- BR9100519A BR9100519A BR919100519A BR9100519A BR9100519A BR 9100519 A BR9100519 A BR 9100519A BR 919100519 A BR919100519 A BR 919100519A BR 9100519 A BR9100519 A BR 9100519A BR 9100519 A BR9100519 A BR 9100519A
- Authority
- BR
- Brazil
- Prior art keywords
- mammal
- treat
- disease
- compound
- pharmaceutical composition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US47692890A | 1990-02-08 | 1990-02-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9100519A true BR9100519A (pt) | 1991-10-29 |
Family
ID=23893824
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR919100519A BR9100519A (pt) | 1990-02-08 | 1991-02-07 | Composto,composicao farmaceutica,metodo para inibicao de colinesterase em um mamifero e metodo para melhorar a memoria ou tratar ou prevenir a doenca de alzheimer |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0441517A3 (pt) |
| JP (1) | JPH07119214B2 (pt) |
| KR (1) | KR950013562B1 (pt) |
| CN (1) | CN1054600A (pt) |
| AU (1) | AU631723B2 (pt) |
| BR (1) | BR9100519A (pt) |
| CA (1) | CA2035805C (pt) |
| CS (1) | CS29991A2 (pt) |
| DE (1) | DE9101348U1 (pt) |
| EG (1) | EG19644A (pt) |
| FI (1) | FI910592A (pt) |
| HU (1) | HUT70051A (pt) |
| IE (1) | IE910402A1 (pt) |
| IL (1) | IL97140A (pt) |
| NO (1) | NO177534C (pt) |
| NZ (1) | NZ237040A (pt) |
| PL (2) | PL167078B1 (pt) |
| PT (1) | PT96681A (pt) |
| TW (1) | TW197442B (pt) |
| YU (1) | YU21391A (pt) |
| ZA (1) | ZA91916B (pt) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2807577B2 (ja) * | 1990-06-15 | 1998-10-08 | エーザイ株式会社 | 環状アミド誘導体 |
| EP0475908A1 (de) * | 1990-09-14 | 1992-03-18 | Ciba-Geigy Ag | Chromogene Lactamverbindungen und ihre Herstellung und Verwendung |
| TW263504B (pt) * | 1991-10-03 | 1995-11-21 | Pfizer | |
| TW248556B (pt) * | 1993-01-18 | 1995-06-01 | Takeda Pharm Industry Co | |
| US5620973A (en) * | 1993-11-30 | 1997-04-15 | Takeda Chemical Industries, Ltd. | Tetracyclic condensed heterocyclic compounds and their use |
| KR100639543B1 (ko) | 1998-09-30 | 2006-10-31 | 다케다 야쿠힌 고교 가부시키가이샤 | 방광 배출력 개선제 |
| MXPA05004715A (es) * | 2002-10-30 | 2005-08-03 | Merck Frosst Canada Inc | Derivados de piridopirrolizina y piridoindolizina. |
| US7601856B2 (en) | 2006-07-27 | 2009-10-13 | Wyeth | Benzofurans as potassium ion channel modulators |
| US7662831B2 (en) | 2006-07-27 | 2010-02-16 | Wyeth Llc | Tetracyclic indoles as potassium channel modulators |
| WO2012038966A1 (en) | 2010-09-22 | 2012-03-29 | Tyche Industries Ltd. | Process for the preparation of donepezil intermediate |
| PL3680243T3 (pl) * | 2017-09-07 | 2022-02-14 | Eisai R&D Management Co., Ltd. | Związek pentacykliczny |
| EA202191966A1 (ru) | 2019-03-05 | 2021-12-08 | Эйсай Ар Энд Ди Менеджмент Ко., Лтд. | Пентациклическое гетероциклическое соединение |
| EP3936189A4 (en) | 2019-03-05 | 2022-12-14 | Eisai R&D Management Co., Ltd. | SALT OF A PENTACYCLIC COMPOUND AND CRYSTALS THEREOF |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3910947A (en) * | 1969-07-24 | 1975-10-07 | Sandoz Ag | Preparation of imidazo{8 2,1-a{9 isoindoles |
| IT1199076B (it) * | 1984-03-01 | 1988-12-30 | Consiglio Nazionale Ricerche | Derivati della fisostigmina con proprieta'di inibizione della aceticolinesterasi e relativo procedimento di produzione |
| US4563469A (en) * | 1984-07-20 | 1986-01-07 | Warner-Lambert Company | Derivatives of N-[2-(tetrahydro-3,5-dioxo-1H-pyrrolizin-7a(5H)-yl)ethyl]amine as cognition activators |
| EP0187619A3 (de) * | 1985-01-03 | 1987-08-26 | Ciba-Geigy Ag | 1,3-disubstituierte Tetrahydropyridine |
| US4791107A (en) * | 1986-07-16 | 1988-12-13 | Hoechst-Roussel Pharmaceuticals, Inc. | Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use |
| US4778812A (en) * | 1987-06-12 | 1988-10-18 | American Home Products Corporation | 2,3-dihydro-9-methyl-1H-pyrrolo[1,2-a]indol-1-amines and derivatives thereof |
| EP0351283A1 (fr) * | 1988-07-12 | 1990-01-17 | Synthelabo | Dérivés de [(pipéridinyl-4) méthyl]-2 dihydro-2,3 1H-isoindole et tétrahydro-2,3,4,5 1H-benzazépines, leur préparation et leur application en thérapeutique |
-
1991
- 1991-01-23 TW TW080100556A patent/TW197442B/zh active
- 1991-01-29 EP EP19910300662 patent/EP0441517A3/en not_active Withdrawn
- 1991-02-03 IL IL9714091A patent/IL97140A/en not_active IP Right Cessation
- 1991-02-06 PL PL91304632A patent/PL167078B1/pl unknown
- 1991-02-06 CA CA002035805A patent/CA2035805C/en not_active Expired - Fee Related
- 1991-02-06 PL PL91288977A patent/PL166757B1/pl unknown
- 1991-02-06 DE DE9101348U patent/DE9101348U1/de not_active Expired - Lifetime
- 1991-02-06 PT PT96681A patent/PT96681A/pt unknown
- 1991-02-07 HU HU91406A patent/HUT70051A/hu unknown
- 1991-02-07 BR BR919100519A patent/BR9100519A/pt not_active Application Discontinuation
- 1991-02-07 CN CN91100860A patent/CN1054600A/zh active Pending
- 1991-02-07 ZA ZA91916A patent/ZA91916B/xx unknown
- 1991-02-07 YU YU21391A patent/YU21391A/sh unknown
- 1991-02-07 CS CS91299A patent/CS29991A2/cs unknown
- 1991-02-07 EG EG7591A patent/EG19644A/xx active
- 1991-02-07 NO NO910473A patent/NO177534C/no unknown
- 1991-02-07 IE IE040291A patent/IE910402A1/en unknown
- 1991-02-07 FI FI910592A patent/FI910592A/fi not_active Application Discontinuation
- 1991-02-07 KR KR1019910002113A patent/KR950013562B1/ko active IP Right Grant
- 1991-02-07 AU AU70879/91A patent/AU631723B2/en not_active Ceased
- 1991-02-07 NZ NZ237040A patent/NZ237040A/xx unknown
- 1991-02-08 JP JP3103992A patent/JPH07119214B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| HU910406D0 (en) | 1991-08-28 |
| DE9101348U1 (pt) | 1991-06-06 |
| HUT70051A (en) | 1995-09-28 |
| NO910473L (no) | 1991-08-09 |
| JPH04234845A (ja) | 1992-08-24 |
| CN1054600A (zh) | 1991-09-18 |
| IL97140A (en) | 1995-07-31 |
| EG19644A (en) | 1995-08-30 |
| EP0441517A2 (en) | 1991-08-14 |
| PT96681A (pt) | 1991-10-31 |
| YU21391A (sh) | 1994-01-20 |
| NO910473D0 (no) | 1991-02-07 |
| EP0441517A3 (en) | 1992-08-19 |
| CS29991A2 (en) | 1991-09-15 |
| PL288977A1 (en) | 1992-01-13 |
| PL166757B1 (pl) | 1995-06-30 |
| IE910402A1 (en) | 1991-08-14 |
| KR910015580A (ko) | 1991-09-30 |
| FI910592A0 (fi) | 1991-02-07 |
| FI910592A (fi) | 1991-08-09 |
| NO177534C (no) | 1995-10-04 |
| PL167078B1 (pl) | 1995-07-31 |
| IL97140A0 (en) | 1992-05-25 |
| NO177534B (no) | 1995-06-26 |
| KR950013562B1 (ko) | 1995-11-09 |
| AU7087991A (en) | 1991-08-29 |
| NZ237040A (en) | 1993-10-26 |
| AU631723B2 (en) | 1992-12-03 |
| TW197442B (pt) | 1993-01-01 |
| JPH07119214B2 (ja) | 1995-12-20 |
| ZA91916B (en) | 1992-09-30 |
| CA2035805C (en) | 1995-06-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| LU91131I2 (fr) | Duloxétine et ses sels d'addition acides pharmaceutiquement acceptables, et en particulier, chlorhydrate de duloxétine. | |
| LV12438A (en) | Metode of preventing and delyaing the onset of alzheimer's disease and composition thereof | |
| LU91452I2 (fr) | "Mycafungine et ses sels pharmaceutiquement acceptables(MYCAMINEr)" | |
| BR9100519A (pt) | Composto,composicao farmaceutica,metodo para inibicao de colinesterase em um mamifero e metodo para melhorar a memoria ou tratar ou prevenir a doenca de alzheimer | |
| LU90334I2 (fr) | Raloxifene et ses sels et dérivés pharmaceutiquement acceptables | |
| EP0587377A3 (en) | Thiazolidinone derivatives as hypoglycemic agents and for treating alzheimer's disease | |
| KR970704445A (ko) | 페노티아진 및/또는 티옥산틴을 사용한 알츠하이머 병의 치료 및/또는 예방 방법(methods for treating and/or preventing alzheimer's disease using phenothiazines and/or thioxanthenes | |
| CA2289717A1 (en) | Novel therapy for constipation | |
| BR1100507A (pt) | Processo para melhorar o desempenho de dissolução de um composto farmacêutico em uma forma de dosagem sólida. | |
| FI953915A0 (fi) | Dupuytrenin taudin lievittämiseen | |
| BR9100046A (pt) | Derivados de azaoxindole,composicao farmaceutica e processo para o tratamento de mamiferos | |
| BR9714145B1 (pt) | composto ou seu sal farmaceuticamente aceitável e composição farmacêutica compreendendo o mencionado composto. | |
| EP0616032A3 (en) | Preventive or therapeutic agents for Alzheimer's disease, a seven-test method, and human tau protein kinase. | |
| BR9607346A (pt) | Composto utilizaç o de um composto composiç o farmacéutica e processo para o tratamento de um mamifero e para e preparaç o de compostos | |
| MX9102701A (es) | Derivados de 2-acilamido de 3,4-dihidro-3-oxo-quinoxalina que tienen actividad farmaceutica. | |
| BR9711225A (pt) | Composi-{es de propentofilina transd-rmica para o tratamento do mal de alzheimer | |
| BR9407265A (pt) | Composto composições farmacêuticas e métodos para tratamento de câncer em um mamifero | |
| BR9401965A (pt) | Composição farmecêutica antialérgica para administração tópica oftálmica e processo para produzir a mesma | |
| BR9505995A (pt) | Composto método para tratamentos e composição farmacêutica | |
| ZA974506B (en) | Medicament comprising a carnitine derivative for treating Alzheimer's disease in early-onset patients. | |
| HU9700661D0 (en) | Use of alpha-1-adrenoreceptor antagonists for profilacting and treating cancer | |
| BR9808305A (pt) | Forma hidratada cristalina, processo para a preparação da forma hidratada cristalina, composição farmacêutica, processo de tratamento de um mamìfero, e, processo de tratamento ou de prevenção de dor. | |
| BR8904508A (pt) | Composto,processo para sua preparacao,composicao e processo para o combate ou prevencao de doencas em plantas e aplicacao | |
| FR2739778B1 (fr) | Formulation topique destinee a traiter la maladie de la douve du foie chez l'animal | |
| EP0349589A4 (en) | PHARMACOLOGICALLY ACTIVE CHOLINERGE PREPARATIONS AND METHOD FOR THE PRODUCTION AND THEIR USE FOR TREATING DISEASES. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EG | Technical examination (opinion): publication of technical examination (opinion) | ||
| FC | Decision: refusal | ||
| FC | Decision: refusal |