BG95935A - Метод и средство за приемане на дексмедетомидин директно през кожата - Google Patents

Метод и средство за приемане на дексмедетомидин директно през кожата

Info

Publication number
BG95935A
BG95935A BG095935A BG9593592A BG95935A BG 95935 A BG95935 A BG 95935A BG 095935 A BG095935 A BG 095935A BG 9593592 A BG9593592 A BG 9593592A BG 95935 A BG95935 A BG 95935A
Authority
BG
Bulgaria
Prior art keywords
skin
agent
directly
administering dexmedetomidine
dexmedetomidine
Prior art date
Application number
BG095935A
Other languages
English (en)
Inventor
Kenneth Colley
Donald Wilson
Gary Cleary
Risto Lammintausta
Harry Jalonen
Original Assignee
Cygnus Research Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cygnus Research Corporation filed Critical Cygnus Research Corporation
Publication of BG95935A publication Critical patent/BG95935A/bg

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061Polyacrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BG095935A 1989-08-18 1992-02-17 Метод и средство за приемане на дексмедетомидин директно през кожата BG95935A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/395,717 US5124157A (en) 1989-08-18 1989-08-18 Method and device for administering dexmedetomidine transdermally
PCT/US1990/004575 WO1991002505A1 (en) 1989-08-18 1990-08-14 Method and device for administering dexmedetomidine transdermally

Publications (1)

Publication Number Publication Date
BG95935A true BG95935A (bg) 1993-12-24

Family

ID=23564195

Family Applications (1)

Application Number Title Priority Date Filing Date
BG095935A BG95935A (bg) 1989-08-18 1992-02-17 Метод и средство за приемане на дексмедетомидин директно през кожата

Country Status (25)

Country Link
US (1) US5124157A (bg)
EP (1) EP0413487B1 (bg)
JP (1) JP3043064B2 (bg)
CN (1) CN1035922C (bg)
AT (1) ATE122899T1 (bg)
AU (1) AU639015B2 (bg)
BG (1) BG95935A (bg)
CA (1) CA2064687C (bg)
DD (1) DD297066A5 (bg)
DE (1) DE69019628T2 (bg)
DK (1) DK0413487T3 (bg)
ES (1) ES2072397T3 (bg)
FI (1) FI100857B (bg)
HU (1) HUT64223A (bg)
IE (1) IE67127B1 (bg)
LT (1) LT3753B (bg)
LV (1) LV10685B (bg)
NO (1) NO300408B1 (bg)
NZ (1) NZ234749A (bg)
PL (1) PL165023B1 (bg)
PT (1) PT95002B (bg)
RU (1) RU2098083C1 (bg)
UA (1) UA26988C2 (bg)
WO (1) WO1991002505A1 (bg)
ZA (1) ZA906539B (bg)

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AU2782592A (en) * 1991-10-15 1993-05-21 Cygnus Therapeutic Systems Thermal enhancement of transdermal drug administration
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US5635203A (en) * 1994-09-29 1997-06-03 Alza Corporation Transdermal device having decreased delamination
US5807570A (en) * 1995-09-29 1998-09-15 Cygnus, Inc. Transdermal administration of ropinirole and analogs thereof
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US5730721A (en) * 1996-01-25 1998-03-24 Vesture Corporation Medical applicator and method
GB9614098D0 (en) 1996-07-05 1996-09-04 Orion Yhtymae Oy Transdermal delivery of levosimendan
DE19814084B4 (de) * 1998-03-30 2005-12-22 Lts Lohmann Therapie-Systeme Ag D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung
AR015744A1 (es) * 1998-04-01 2001-05-16 Orion Corp Uso de dexmedetomidina para sedacion en terapia intensiva
US6716867B1 (en) 1998-04-01 2004-04-06 Orion Corporation Use of dexmedetomidine for ICU sedation
DE19925338A1 (de) * 1999-06-02 2000-12-07 Lohmann Therapie Syst Lts Substratabschnitte mit erhöhter Lagerstabilität während ihrer Lagerung in Beutelverpackung, sowie Verfahren zu ihrer Herstellung
CA2388979C (en) 1999-10-29 2010-09-14 Orion Corporation Treatment or prevention of hypotension and shock with use of an imidazole derivative
WO2001041745A1 (en) 1999-12-10 2001-06-14 Lectec Corporation Anti pruritic patch
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US20030026830A1 (en) * 2001-05-08 2003-02-06 Thomas Lauterback Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine
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US8246979B2 (en) 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system for the administration of rotigotine
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US8246980B2 (en) * 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system
IL152574A (en) * 2002-10-31 2009-09-22 Transpharma Medical Ltd A system for passing through the skin of dry items or dried medicines
US7383084B2 (en) 2002-10-31 2008-06-03 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized medications
US7662404B2 (en) 2002-10-31 2010-02-16 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized peptides and polypeptides
US8133505B2 (en) 2002-10-31 2012-03-13 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized medications
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DE102006054733A1 (de) * 2006-11-21 2008-05-29 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches Systems mit hoher Wirkstoffausnutzungsrate und Dosiergenauigkeit
US20090291127A1 (en) * 2008-05-21 2009-11-26 Jianye Wen Transdermal anti-dementia active agent formulations and methods for using the same
US7795263B2 (en) * 2008-07-08 2010-09-14 Wildlife Laboratories, Inc. Pharmaceutical combination for and method of anesthetizing and immobilizing non-domesticated mammals
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US20130096170A1 (en) 2011-10-14 2013-04-18 Hospira, Inc. Methods of treating pediatric patients using dexmedetomidine
SG11201403094TA (en) 2011-12-11 2014-10-30 Recro Pharma Inc Intranasal dexmedetomidine compositions and methods of use thereof
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KR101831290B1 (ko) 2013-10-07 2018-02-22 테이코쿠 팔마 유에스에이, 인코포레이티드 덱스메데토미딘 경피 조성물을 사용하여 주의력 결핍 과잉행동 장애, 불안 및 불면증을 치료하기 위한 방법 및 조성물
KR101891186B1 (ko) * 2013-10-07 2018-08-24 테이코쿠 팔마 유에스에이, 인코포레이티드 덱스메데토미딘 경피 조성물을 포함하는 통증을 관리하기 위한 방법 및 조성물
TWI704933B (zh) * 2013-10-07 2020-09-21 美商帝國製藥美國股份有限公司 右美托咪啶經皮輸送裝置及使用其之方法
CN105764496B (zh) * 2013-10-07 2020-09-25 帝国制药美国公司 用于经皮递送非镇静量的右旋美托咪啶的方法和组合物
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CN110114069B (zh) * 2016-12-26 2022-03-04 久光制药株式会社 微针装置
US11160791B2 (en) 2018-11-01 2021-11-02 Medefil, Inc. Dexmedetomidine injection premix formulation in ready to use (RTU) bags
CN111346072B (zh) * 2018-12-21 2022-05-27 宜昌人福药业有限责任公司 一种透皮给药的药物组合物及其制备方法
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Also Published As

Publication number Publication date
CA2064687A1 (en) 1991-02-19
LTIP1773A (en) 1995-07-25
JP3043064B2 (ja) 2000-05-22
PL165023B1 (pl) 1994-11-30
EP0413487A1 (en) 1991-02-20
RU2098083C1 (ru) 1997-12-10
HUT64223A (en) 1993-12-28
AU6183490A (en) 1991-04-03
ZA906539B (en) 1991-06-26
PT95002B (pt) 1997-10-31
NZ234749A (en) 1992-03-26
UA26988C2 (uk) 2000-02-28
PT95002A (pt) 1992-02-28
EP0413487B1 (en) 1995-05-24
IE67127B1 (en) 1996-03-06
CN1035922C (zh) 1997-09-24
CN1049450A (zh) 1991-02-27
LT3753B (en) 1996-03-25
ATE122899T1 (de) 1995-06-15
AU639015B2 (en) 1993-07-15
WO1991002505A1 (en) 1991-03-07
NO920521D0 (no) 1992-02-10
US5124157A (en) 1992-06-23
DD297066A5 (de) 1992-01-02
JPH05503916A (ja) 1993-06-24
DK0413487T3 (da) 1995-07-17
FI920576A0 (fi) 1992-02-11
ES2072397T3 (es) 1995-07-16
PL286525A1 (en) 1991-05-20
CA2064687C (en) 1998-04-21
DE69019628T2 (de) 1995-09-28
FI100857B (fi) 1998-03-13
HU9200517D0 (en) 1992-05-28
IE902993A1 (en) 1991-02-27
DE69019628D1 (de) 1995-06-29
NO300408B1 (no) 1997-05-26
LV10685B (en) 1995-12-20
LV10685A (lv) 1995-06-20
NO920521L (no) 1992-02-10

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