ZA906539B - Method and device for administering dexmedetomidine transdermally - Google Patents

Method and device for administering dexmedetomidine transdermally

Info

Publication number
ZA906539B
ZA906539B ZA906539A ZA906539A ZA906539B ZA 906539 B ZA906539 B ZA 906539B ZA 906539 A ZA906539 A ZA 906539A ZA 906539 A ZA906539 A ZA 906539A ZA 906539 B ZA906539 B ZA 906539B
Authority
ZA
South Africa
Prior art keywords
administering
dexmedetomidine
adhesive layer
therapeutic system
transdermally
Prior art date
Application number
ZA906539A
Other languages
English (en)
Inventor
Kenneth J Colley
J Colley Kenneth
Donald R Wilson
R Wilson Donald
Gary W Cleary
W Cleary Gary
Risto Lammintausta
Lammintausta Risto
Harry Jalonen
Jalonen Harry
Original Assignee
Cygnus Research Corp
Orion Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cygnus Research Corp, Orion Corp filed Critical Cygnus Research Corp
Publication of ZA906539B publication Critical patent/ZA906539B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA906539A 1989-08-18 1990-08-17 Method and device for administering dexmedetomidine transdermally ZA906539B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/395,717 US5124157A (en) 1989-08-18 1989-08-18 Method and device for administering dexmedetomidine transdermally

Publications (1)

Publication Number Publication Date
ZA906539B true ZA906539B (en) 1991-06-26

Family

ID=23564195

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA906539A ZA906539B (en) 1989-08-18 1990-08-17 Method and device for administering dexmedetomidine transdermally

Country Status (25)

Country Link
US (1) US5124157A (xx)
EP (1) EP0413487B1 (xx)
JP (1) JP3043064B2 (xx)
CN (1) CN1035922C (xx)
AT (1) ATE122899T1 (xx)
AU (1) AU639015B2 (xx)
BG (1) BG95935A (xx)
CA (1) CA2064687C (xx)
DD (1) DD297066A5 (xx)
DE (1) DE69019628T2 (xx)
DK (1) DK0413487T3 (xx)
ES (1) ES2072397T3 (xx)
FI (1) FI100857B (xx)
HU (1) HUT64223A (xx)
IE (1) IE67127B1 (xx)
LT (1) LT3753B (xx)
LV (1) LV10685B (xx)
NO (1) NO300408B1 (xx)
NZ (1) NZ234749A (xx)
PL (1) PL165023B1 (xx)
PT (1) PT95002B (xx)
RU (1) RU2098083C1 (xx)
UA (1) UA26988C2 (xx)
WO (1) WO1991002505A1 (xx)
ZA (1) ZA906539B (xx)

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US5635203A (en) * 1994-09-29 1997-06-03 Alza Corporation Transdermal device having decreased delamination
US5807570A (en) * 1995-09-29 1998-09-15 Cygnus, Inc. Transdermal administration of ropinirole and analogs thereof
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AR015744A1 (es) * 1998-04-01 2001-05-16 Orion Corp Uso de dexmedetomidina para sedacion en terapia intensiva
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US20020198215A1 (en) * 2000-10-23 2002-12-26 Lino Tavares Terazosin transdermal device and methods
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US20030026830A1 (en) * 2001-05-08 2003-02-06 Thomas Lauterback Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine
US20030027793A1 (en) * 2001-05-08 2003-02-06 Thomas Lauterback Transdermal treatment of parkinson's disease
US8246980B2 (en) * 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system
US8211462B2 (en) * 2002-07-30 2012-07-03 Ucb Pharma Gmbh Hot-melt TTS for administering rotigotine
US8246979B2 (en) 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system for the administration of rotigotine
DE10234673B4 (de) * 2002-07-30 2007-08-16 Schwarz Pharma Ag Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren
US7662404B2 (en) 2002-10-31 2010-02-16 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized peptides and polypeptides
US7383084B2 (en) 2002-10-31 2008-06-03 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized medications
IL152574A (en) 2002-10-31 2009-09-22 Transpharma Medical Ltd A system for passing through the skin of dry items or dried medicines
US8133505B2 (en) 2002-10-31 2012-03-13 Transpharma Medical Ltd. Transdermal delivery system for dried particulate or lyophilized medications
ES2239196T3 (es) * 2002-12-02 2005-09-16 Schwarz Pharma Ag Suministro iontoforetico de rotigotina para el tratamiento de la enfermedad de parkinson.
DE10261696A1 (de) 2002-12-30 2004-07-15 Schwarz Pharma Ag Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base
DE102006054733A1 (de) * 2006-11-21 2008-05-29 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches Systems mit hoher Wirkstoffausnutzungsrate und Dosiergenauigkeit
US20090291127A1 (en) * 2008-05-21 2009-11-26 Jianye Wen Transdermal anti-dementia active agent formulations and methods for using the same
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US20130096170A1 (en) 2011-10-14 2013-04-18 Hospira, Inc. Methods of treating pediatric patients using dexmedetomidine
EP2787970B1 (en) 2011-12-11 2018-04-11 Recro Pharma, Inc. Intranasal dexmedetomidine compositions and methods of use thereof
US8242158B1 (en) 2012-01-04 2012-08-14 Hospira, Inc. Dexmedetomidine premix formulation
WO2013173317A1 (en) * 2012-05-14 2013-11-21 Prospire, Llc TREATMENT OF OBSTRUCTIVE SLEEP APNEA WITH α2-ADRENERGIC RECEPTOR AGONISTS
EP3054930B1 (en) * 2013-10-07 2020-12-02 Teikoku Pharma USA, Inc. Methods and compositions for transdermal delivery of a non-sedative amount of dexmedetomidine
EP3054934B1 (en) * 2013-10-07 2024-05-22 Teikoku Pharma USA, Inc. Methods and compositions for treating withdrawal syndromes using non-sedative dexmedetomidine transdermal compositions
CN105764494A (zh) * 2013-10-07 2016-07-13 帝国制药美国公司 右旋美托咪啶经皮递送装置及其使用方法
WO2015054059A2 (en) * 2013-10-07 2015-04-16 Teikoku Pharma Usa, Inc. Methods and compositions for treating attention deficit hyperactivity disorder, anxiety and insomnia using dexmedetomidine transdermal compositions
TWI629061B (zh) * 2013-10-07 2018-07-11 美商帝國製藥美國股份有限公司 包含右美托嘧啶（ｄｅｘｍｅｄｅｔｏｍｉｄｉｎｅ）經皮組成物之疼痛處理用方法及組成物
EP3087985B1 (en) * 2013-12-18 2018-10-17 Maruishi Pharmaceutical Co., Ltd. Hydrous adhesive patch
US9717796B1 (en) 2016-04-20 2017-08-01 Slypharma, Llc Heat sterilizeable, premixed, ready to use dexmedetomidine solution packaged in a flexible plastic container
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Also Published As

Publication number Publication date
AU6183490A (en) 1991-04-03
FI100857B (fi) 1998-03-13
HU9200517D0 (en) 1992-05-28
IE902993A1 (en) 1991-02-27
DE69019628D1 (de) 1995-06-29
PL165023B1 (pl) 1994-11-30
JP3043064B2 (ja) 2000-05-22
LT3753B (en) 1996-03-25
DK0413487T3 (da) 1995-07-17
DD297066A5 (de) 1992-01-02
ATE122899T1 (de) 1995-06-15
UA26988C2 (uk) 2000-02-28
AU639015B2 (en) 1993-07-15
BG95935A (bg) 1993-12-24
PL286525A1 (en) 1991-05-20
CA2064687A1 (en) 1991-02-19
LTIP1773A (en) 1995-07-25
EP0413487B1 (en) 1995-05-24
LV10685A (lv) 1995-06-20
WO1991002505A1 (en) 1991-03-07
LV10685B (en) 1995-12-20
NZ234749A (en) 1992-03-26
NO920521D0 (no) 1992-02-10
PT95002A (pt) 1992-02-28
IE67127B1 (en) 1996-03-06
PT95002B (pt) 1997-10-31
NO920521L (no) 1992-02-10
CN1049450A (zh) 1991-02-27
NO300408B1 (no) 1997-05-26
DE69019628T2 (de) 1995-09-28
EP0413487A1 (en) 1991-02-20
US5124157A (en) 1992-06-23
HUT64223A (en) 1993-12-28
RU2098083C1 (ru) 1997-12-10
CA2064687C (en) 1998-04-21
JPH05503916A (ja) 1993-06-24
ES2072397T3 (es) 1995-07-16
CN1035922C (zh) 1997-09-24
FI920576A0 (fi) 1992-02-11

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