KR970704445A - 페노티아진 및/또는 티옥산틴을 사용한 알츠하이머 병의 치료 및/또는 예방 방법(methods for treating and/or preventing alzheimer's disease using phenothiazines and/or thioxanthenes - Google Patents
페노티아진 및/또는 티옥산틴을 사용한 알츠하이머 병의 치료 및/또는 예방 방법(methods for treating and/or preventing alzheimer's disease using phenothiazines and/or thioxanthenesInfo
- Publication number
- KR970704445A KR970704445A KR1019970700943A KR19970700943A KR970704445A KR 970704445 A KR970704445 A KR 970704445A KR 1019970700943 A KR1019970700943 A KR 1019970700943A KR 19970700943 A KR19970700943 A KR 19970700943A KR 970704445 A KR970704445 A KR 970704445A
- Authority
- KR
- South Korea
- Prior art keywords
- thioxanthenes
- phenothiazines
- disease
- treating
- preventing alzheimer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28733994A | 1994-08-08 | 1994-08-08 | |
US34675794A | 1994-11-30 | 1994-11-30 | |
PCT/US1995/010110 WO1996004915A1 (en) | 1994-08-08 | 1995-08-07 | Methods for treating and/or preventing alzheimer's disease using phenothiazines and/or thioxanthenes |
Publications (1)
Publication Number | Publication Date |
---|---|
KR970704445A true KR970704445A (ko) | 1997-09-06 |
Family
ID=26964404
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019970700943A KR970704445A (ko) | 1994-08-08 | 1997-02-10 | 페노티아진 및/또는 티옥산틴을 사용한 알츠하이머 병의 치료 및/또는 예방 방법(methods for treating and/or preventing alzheimer's disease using phenothiazines and/or thioxanthenes |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0778773A1 (ko) |
KR (1) | KR970704445A (ko) |
AU (1) | AU708682B2 (ko) |
CA (1) | CA2196529A1 (ko) |
WO (1) | WO1996004915A1 (ko) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9506197D0 (en) | 1995-03-27 | 1995-05-17 | Hoffmann La Roche | Inhibition of tau-tau association. |
GB9713484D0 (en) * | 1997-06-27 | 1997-09-03 | Smithkline Beecham Plc | Neuroprotective vanilloid compounds |
DE19842416A1 (de) * | 1998-09-16 | 2000-04-13 | Max Planck Gesellschaft | Sekundäre Amine zur Prävention und Therapie von Erkrankungen, die durch Oxidationsprozesse verursacht oder verstärkt werden |
GB0017060D0 (en) * | 2000-07-11 | 2000-08-30 | Hunter Fleming Ltd | Production, stabilisation and use of reduced forms of pharmaceutical compounds |
GB0100119D0 (en) | 2001-01-03 | 2001-02-14 | Univ Aberdeen | Materials and methods relating to protein aggregation in neurodegenerative disease |
GB0101049D0 (en) | 2001-01-15 | 2001-02-28 | Univ Aberdeen | Materials and methods relating to protein aggregation in neurodegenerative disease |
GB0106953D0 (en) | 2001-03-20 | 2001-05-09 | Univ Aberdeen | Neufofibrillary labels |
GB0117326D0 (en) | 2001-07-16 | 2001-09-05 | Univ Aberdeen | Napthoquinone-type inhibitors of protein aggregation |
ES2272911T3 (es) * | 2003-04-25 | 2007-05-01 | Neurofit Sas | Uso de derivados de fenotiazina piperazina en la fabricacion de un medicamento con efectos neuroprotector y/o neurotroficos sobre cns y/o pns. |
CN101084204B (zh) | 2004-09-23 | 2012-12-05 | 卫思道制药有限公司 | 包括亚甲蓝(mtc)在内的二氨基吩噻嗪鎓化合物的化学合成和纯化方法 |
CA2592320C (en) | 2004-12-22 | 2015-11-24 | Neurochem (International) Limited | Methods and compositions for treating amyloid-related diseases |
AU2007231126B2 (en) | 2006-03-29 | 2012-11-01 | Wista Laboratories Ltd. | Inhibitors of protein aggregation |
EP2853293B1 (en) * | 2006-03-29 | 2017-11-22 | WisTa Laboratories Ltd. | Thioninium compounds and their use |
PT2013191E (pt) | 2006-03-29 | 2010-10-29 | Wista Lab Ltd | Sais de 3,7-diamino-10h-fenotiazina e a sua utilização |
CA2666246C (en) | 2006-10-12 | 2013-12-31 | Bellus Health (International) Limited | Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid |
GB0701970D0 (en) * | 2007-02-01 | 2007-03-14 | Wilson Stuart | Treatment of protein aggregation diseases |
ES2331282B1 (es) * | 2008-06-25 | 2010-10-21 | Consejo Superior De Investigaciones Cientificas (Csic) (45%) | Hidrazidas de sistemas heterociclicos y su uso en el tratamiento de enfermedades neurodegenerativas. |
DE102010062810B4 (de) * | 2010-09-07 | 2014-03-13 | Immungenetics Ag | 2-(R2-Thio)-10-[3-(4-R1-piperazin-1-yl)propyl]-10H-phenothiazine zur Behandlung neurodegenerativer Erkrankungen ausgewählt aus beta-Amyloidopathien und alpha-Synucleinopathien |
US9283230B2 (en) | 2011-02-11 | 2016-03-15 | Wista Laboratories Ltd. | Phenothiazine diaminium salts and their use |
US8980884B2 (en) * | 2011-06-01 | 2015-03-17 | Wisconsin Alumni Research Foundation | Methods for treating Alzheimer's disease |
JP2023549174A (ja) * | 2020-11-04 | 2023-11-22 | グリアセルテック・インコーポレイテッド | クロルプロマジンを含む神経炎症性疾患の予防または治療用組成物 |
WO2022104070A2 (en) * | 2020-11-13 | 2022-05-19 | Icahn School Of Medicine At Mount Sinai | Phenothiazine compounds for the treatment of alzheimer's disease and other age-related and neurological diseases |
WO2023131606A1 (en) * | 2022-01-04 | 2023-07-13 | Immungenetics Ag | Specific dosage of phenothiazine compounds for use in treatment or prevention of alzheimer's dementia |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2837518A (en) * | 1958-06-03 | Phenthiazine compounds | ||
US2902484A (en) * | 1954-04-27 | 1959-09-01 | Rhone Poulenc Sa | Phenthiazine derivatives and processes for their preparation |
NL108827C (ko) * | 1956-04-09 |
-
1995
- 1995-08-07 EP EP95929441A patent/EP0778773A1/en not_active Withdrawn
- 1995-08-07 WO PCT/US1995/010110 patent/WO1996004915A1/en not_active Application Discontinuation
- 1995-08-07 CA CA002196529A patent/CA2196529A1/en not_active Abandoned
- 1995-08-07 AU AU32793/95A patent/AU708682B2/en not_active Ceased
-
1997
- 1997-02-10 KR KR1019970700943A patent/KR970704445A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO1996004915A1 (en) | 1996-02-22 |
CA2196529A1 (en) | 1996-02-22 |
AU3279395A (en) | 1996-03-07 |
EP0778773A1 (en) | 1997-06-18 |
AU708682B2 (en) | 1999-08-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |