DE69427517T2 - Tetracyclische kondensierte heterocyclische Verbindungen zur Behandlung von seniler Demenz - Google Patents

Tetracyclische kondensierte heterocyclische Verbindungen zur Behandlung von seniler Demenz

Info

Publication number
DE69427517T2
DE69427517T2 DE69427517T DE69427517T DE69427517T2 DE 69427517 T2 DE69427517 T2 DE 69427517T2 DE 69427517 T DE69427517 T DE 69427517T DE 69427517 T DE69427517 T DE 69427517T DE 69427517 T2 DE69427517 T2 DE 69427517T2
Authority
DE
Germany
Prior art keywords
senile dementia
treatment
heterocyclic compounds
condensed heterocyclic
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69427517T
Other languages
English (en)
Other versions
DE69427517D1 (de
Inventor
Giichi Goto
Yuji Ishihara
Masaomi Miyamoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of DE69427517D1 publication Critical patent/DE69427517D1/de
Application granted granted Critical
Publication of DE69427517T2 publication Critical patent/DE69427517T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DE69427517T 1993-11-30 1994-11-29 Tetracyclische kondensierte heterocyclische Verbindungen zur Behandlung von seniler Demenz Expired - Fee Related DE69427517T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP29979993 1993-11-30
JP5598494 1994-03-25

Publications (2)

Publication Number Publication Date
DE69427517D1 DE69427517D1 (de) 2001-07-26
DE69427517T2 true DE69427517T2 (de) 2002-05-29

Family

ID=26396889

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69427517T Expired - Fee Related DE69427517T2 (de) 1993-11-30 1994-11-29 Tetracyclische kondensierte heterocyclische Verbindungen zur Behandlung von seniler Demenz

Country Status (5)

Country Link
US (2) US5620973A (de)
EP (1) EP0655451B1 (de)
AT (1) ATE202354T1 (de)
CA (1) CA2136913A1 (de)
DE (1) DE69427517T2 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5658909A (en) * 1994-11-17 1997-08-19 Molecular Geriatrics Corporation Certain substituted 1-aryl-3-piperazin-1'-yl propanones to treat Alzheimer's Disease
AU6852898A (en) 1997-04-17 1998-11-11 Takeda Chemical Industries Ltd. Thermogenic composition and benzazepine thermogenics
EP1891954A3 (de) 1998-09-30 2009-01-14 Takeda Pharmaceutical Company Limited Wirkstoffe zur Verbesserung der Exkretionskraft der Harnblase
JP2003502332A (ja) 1999-06-14 2003-01-21 ニューロゲン コーポレイション １−アザ三環式−４−ベンジルピペラジン
EP1319661B1 (de) * 2000-09-21 2006-03-01 Takeda Pharmaceutical Company Limited Verfahren zur produktion eines trizyklischen kondensierten heterozyklischen derivats
KR100614862B1 (ko) 2001-12-28 2006-08-22 다케다 야쿠힌 고교 가부시키가이샤 배뇨 장애 예방제/치료제
US20050143350A1 (en) * 2003-11-19 2005-06-30 Seed John C. Combination drug therapy to treat obesity
JPWO2005049622A1 (ja) * 2003-11-19 2007-06-07 日本たばこ産業株式会社 ５−５員縮合複素環化合物及びそのｈｃｖポリメラーゼ阻害剤としての用途
US20070049593A1 (en) * 2004-02-24 2007-03-01 Japan Tobacco Inc. Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor
US7659263B2 (en) 2004-11-12 2010-02-09 Japan Tobacco Inc. Thienopyrrole compound and use thereof as HCV polymerase inhibitor
US7601856B2 (en) 2006-07-27 2009-10-13 Wyeth Benzofurans as potassium ion channel modulators
US7662831B2 (en) 2006-07-27 2010-02-16 Wyeth Llc Tetracyclic indoles as potassium channel modulators
US9040519B2 (en) 2010-02-18 2015-05-26 Medivation Technologies, Inc. Fused tetracyclic pyrido [4,3-B] indole and pyrido [3,4-B] indole derivatives and methods of use
US9034865B2 (en) 2010-02-18 2015-05-19 Medivation Technologies, Inc. Pyrido [4,3-B] indole and pyrido [3,4-B] indole derivatives and methods of use
US9193728B2 (en) 2010-02-18 2015-11-24 Medivation Technologies, Inc. Fused tetracyclic pyrido [4,3-B] indole and pyrido [3,4-B] indole derivatives and methods of use
US20140303144A1 (en) 2011-02-18 2014-10-09 Medivation Technologies, Inc. Compounds and methods of treating hypertension

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3403156A (en) * 1966-06-07 1968-09-24 American Home Prod N-acyl substituted polycylclic isoquinolines
US4192874A (en) * 1978-11-02 1980-03-11 American Hoechst Corporation Substituted 1,2,6,7-tetrahydroindolo[1,7-ab][1,5]benzodiazepines
JP2969359B2 (ja) * 1989-01-13 1999-11-02 武田薬品工業株式会社 環状アミン化合物
WO1991007968A1 (en) * 1989-11-27 1991-06-13 Vsesojuzny Nauchno-Issledovatelsky Khimiko-Farmatsevtichesky Institut Imeni Sergo Ordzhonikidze (Vnikhfi) Hydrochloride 2,3,3a,4,5,6-hexahydro-8-cyclohexyl-1h-pyrazino (3,2,1-j,k)carbazol, method of obtaining it and a pharmaceutical preparation of antidepressive action based on it
TW197442B (de) * 1990-02-08 1993-01-01 Pfizer
JPH0413626A (ja) * 1990-05-01 1992-01-17 Q P Corp 健脳組成物
TW197435B (de) * 1990-11-22 1993-01-01 Takeda Pharm Industry Co Ltd
TW263504B (de) * 1991-10-03 1995-11-21 Pfizer
SE9103752D0 (sv) * 1991-12-18 1991-12-18 Astra Ab New compounds
TW218875B (de) * 1992-03-09 1994-01-11 Takeda Pharm Industry Co Ltd
CA2092112A1 (en) * 1992-03-23 1993-09-24 Nobuyoshi Iwata Indole and indazole derivatives, for the treatment and prophylaxis of cerebral disorders, their preparation and their use
TW248556B (de) * 1993-01-18 1995-06-01 Takeda Pharm Industry Co

Also Published As

Publication number Publication date
ATE202354T1 (de) 2001-07-15
DE69427517D1 (de) 2001-07-26
EP0655451A1 (de) 1995-05-31
CA2136913A1 (en) 1995-05-31
US5620973A (en) 1997-04-15
US5814642A (en) 1998-09-29
EP0655451B1 (de) 2001-06-20

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee