PT94816A - Processo para a preparacao de mono-(2-amonio-2-hidroximetil-1,3-propanodiol)(2rcis)-1,2-epoxipropil-fosfonato,com caracteristicas de estabilidade e processamenento aperfeicoadas e de composicoes farmaceuticas que o contem - Google Patents
Processo para a preparacao de mono-(2-amonio-2-hidroximetil-1,3-propanodiol)(2rcis)-1,2-epoxipropil-fosfonato,com caracteristicas de estabilidade e processamenento aperfeicoadas e de composicoes farmaceuticas que o contemInfo
- Publication number
- PT94816A PT94816A PT94816A PT9481690A PT94816A PT 94816 A PT94816 A PT 94816A PT 94816 A PT94816 A PT 94816A PT 9481690 A PT9481690 A PT 9481690A PT 94816 A PT94816 A PT 94816A
- Authority
- PT
- Portugal
- Prior art keywords
- amisyl
- 2rcis
- propanodiol
- hydroxymethyl
- perforated
- Prior art date
Links
- GYDBYATURBDGIF-UHFFFAOYSA-N (2-methyloxiran-2-yl)phosphonic acid Chemical compound OP(=O)(O)C1(C)CO1 GYDBYATURBDGIF-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65502—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a three-membered ring
- C07F9/65505—Phosphonic acids containing oxirane groups; esters thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8921340A IT1231013B (it) | 1989-07-27 | 1989-07-27 | Mono (2 ammonio 2 idrossimetil 1,3 propandiolo)(2r,cis) 1,2 epossipropil fosfonato avente migliorate caratteristiche di stabilita' e lavorabilita'. |
Publications (2)
Publication Number | Publication Date |
---|---|
PT94816A true PT94816A (pt) | 1991-04-18 |
PT94816B PT94816B (pt) | 1997-03-31 |
Family
ID=11180349
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT94816A PT94816B (pt) | 1989-07-27 | 1990-07-25 | Processo para a preparacao de mono-(2-amonio-2-hidroximetil-1,3-propanodiol)(2rcis)-1,2-epoxipropil-fosfonato,com caracteristicas de estabilidade e processamenento aperfeicoadas e de composicoes farmaceuticas que o contem |
Country Status (19)
Country | Link |
---|---|
US (1) | US5162309A (pt) |
JP (1) | JP2821803B2 (pt) |
AT (1) | AT398204B (pt) |
BE (1) | BE1002775A3 (pt) |
CA (1) | CA2021809A1 (pt) |
CH (1) | CH679669A5 (pt) |
DE (1) | DE4023775C2 (pt) |
DK (1) | DK170777B1 (pt) |
ES (1) | ES2020790A6 (pt) |
FI (1) | FI97232C (pt) |
FR (1) | FR2650280B1 (pt) |
GB (1) | GB2234245B (pt) |
GR (1) | GR1000714B (pt) |
IE (1) | IE63984B1 (pt) |
IT (1) | IT1231013B (pt) |
LU (1) | LU87774A1 (pt) |
NL (1) | NL194504C (pt) |
PT (1) | PT94816B (pt) |
SE (1) | SE468769B (pt) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7303755B2 (en) | 2002-08-01 | 2007-12-04 | Zambon S.P.A. | Pharmaceutical compositions with antibiotic activity |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2244333B1 (es) * | 2004-05-18 | 2006-08-01 | Simbec Iberica, Sl | Preparado farmaceutico oral de fosfomicina estable y apto para diabeticos. |
EP1762573A1 (en) | 2005-09-08 | 2007-03-14 | Interquim, S.A. De C.V. | A process for the preparation of fosfomycin salts |
ES2385158B1 (es) * | 2010-12-24 | 2013-05-28 | Arafarma Group, S.A. | Composición farmacéutica de fosfomicina |
CN102351902A (zh) * | 2011-08-12 | 2012-02-15 | 山西仟源制药股份有限公司 | 磷霉素单氨丁三醇的制备方法 |
CN102807586B (zh) | 2012-08-31 | 2015-05-13 | 东北制药集团股份有限公司 | 磷霉素氨盐的制备方法 |
ITTO20130839A1 (it) * | 2013-10-16 | 2015-04-17 | C & G Farmaceutici S R L | Composizione a base di fosfomicina trometamolo |
DE102014218913A1 (de) * | 2014-09-19 | 2016-03-24 | Heraeus Medical Gmbh | Verfahren zur Herstellung eines antibiotischen Polymehtylmethacrylat-Knochenzementpulvers und ein antibiotisches Polymethtylmethacrylat-Knochenzementpulver |
WO2017111718A1 (en) | 2015-12-25 | 2017-06-29 | Yusuf Toktamiş Öğün | The formulation comprising phosphomycine and ascorbic acid for the treatment of bacterial urinary system infections |
CN108997425B (zh) * | 2017-06-06 | 2020-11-13 | 湖南华纳大药厂手性药物有限公司 | 一种制备高含量磷霉素氨丁三醇的方法 |
CN108997424B (zh) * | 2017-06-06 | 2020-11-13 | 湖南华纳大药厂手性药物有限公司 | 一种简捷制备磷霉素氨丁三醇的方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3641063A (en) * | 1968-01-22 | 1972-02-08 | Merck & Co Inc | Antibiotic purification process |
US3914231A (en) * | 1970-09-04 | 1975-10-21 | Merck & Co Inc | ({31 )(Cis-1,2-epoxypropyl)-phosphonic acid and salts thereof |
IT1112282B (it) * | 1978-07-19 | 1986-01-13 | Zambon Spa | Bis-(2-ammonio-2-idrossimetil-1,3-propandiolo)(2r-cis)-(3-metilossiranil)fosfonato |
IT1124610B (it) * | 1979-10-18 | 1986-05-07 | Zambo Spa | Mono(2-ammonio-2-idrossimetil-1,3-propandiolo) (2r-cis)-(o-metilossiranil)fosfonato |
-
1989
- 1989-07-27 IT IT8921340A patent/IT1231013B/it active
-
1990
- 1990-07-18 IE IE262890A patent/IE63984B1/en not_active IP Right Cessation
- 1990-07-20 CH CH2423/90A patent/CH679669A5/it not_active IP Right Cessation
- 1990-07-24 CA CA002021809A patent/CA2021809A1/en not_active Abandoned
- 1990-07-25 US US07/557,030 patent/US5162309A/en not_active Expired - Lifetime
- 1990-07-25 FR FR909009494A patent/FR2650280B1/fr not_active Expired - Fee Related
- 1990-07-25 LU LU87774A patent/LU87774A1/fr unknown
- 1990-07-25 GR GR900100570A patent/GR1000714B/el not_active IP Right Cessation
- 1990-07-25 PT PT94816A patent/PT94816B/pt not_active IP Right Cessation
- 1990-07-25 GB GB9016253A patent/GB2234245B/en not_active Expired - Fee Related
- 1990-07-26 DE DE4023775A patent/DE4023775C2/de not_active Expired - Fee Related
- 1990-07-26 ES ES9002011A patent/ES2020790A6/es not_active Expired - Fee Related
- 1990-07-26 JP JP2201021A patent/JP2821803B2/ja not_active Expired - Lifetime
- 1990-07-26 AT AT0156590A patent/AT398204B/de not_active IP Right Cessation
- 1990-07-26 SE SE9002501A patent/SE468769B/sv not_active IP Right Cessation
- 1990-07-26 BE BE9000747A patent/BE1002775A3/fr not_active IP Right Cessation
- 1990-07-26 DK DK177990A patent/DK170777B1/da not_active IP Right Cessation
- 1990-07-27 FI FI903760A patent/FI97232C/fi not_active IP Right Cessation
- 1990-07-27 NL NL9001712A patent/NL194504C/nl not_active IP Right Cessation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7303755B2 (en) | 2002-08-01 | 2007-12-04 | Zambon S.P.A. | Pharmaceutical compositions with antibiotic activity |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB1A | Laying open of patent application |
Effective date: 19901226 |
|
FG3A | Patent granted, date of granting |
Effective date: 19961216 |
|
MM3A | Annulment or lapse |
Effective date: 20060616 |