DK177990A - Mono-(2-ammonium-2-hydroxymethyl-1,3-propandiol)(2r,cis)-1,2-epoxypropylphosphonat, fremgangsmaade til fremstilling deraf og faste farmaceutiske praeparater indeholdende forbindelsen - Google Patents

Mono-(2-ammonium-2-hydroxymethyl-1,3-propandiol)(2r,cis)-1,2-epoxypropylphosphonat, fremgangsmaade til fremstilling deraf og faste farmaceutiske praeparater indeholdende forbindelsen Download PDF

Info

Publication number
DK177990A
DK177990A DK177990A DK177990A DK177990A DK 177990 A DK177990 A DK 177990A DK 177990 A DK177990 A DK 177990A DK 177990 A DK177990 A DK 177990A DK 177990 A DK177990 A DK 177990A
Authority
DK
Denmark
Prior art keywords
epoxypropylphosphonate
propandiol
hydroxymethyl
cis
mono
Prior art date
Application number
DK177990A
Other languages
English (en)
Other versions
DK177990D0 (da
DK170777B1 (da
Inventor
Dario Tentorio
Graziano Castaldi
Claudio Giordano
Franco Pozzi
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of DK177990D0 publication Critical patent/DK177990D0/da
Publication of DK177990A publication Critical patent/DK177990A/da
Application granted granted Critical
Publication of DK170777B1 publication Critical patent/DK170777B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65502—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a three-membered ring
    • C07F9/65505—Phosphonic acids containing oxirane groups; esters thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
DK177990A 1989-07-27 1990-07-26 Mono-(2-ammonium-2-hydroxymethyl-1,3-propandiol)(2R,cis)-1,2-epoxypropylphosphonat, fremgangsmåde til dets fremstilling og faste farmaceutiske præpar ater med indhold deraf DK170777B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2134089 1989-07-27
IT8921340A IT1231013B (it) 1989-07-27 1989-07-27 Mono (2 ammonio 2 idrossimetil 1,3 propandiolo)(2r,cis) 1,2 epossipropil fosfonato avente migliorate caratteristiche di stabilita' e lavorabilita'.

Publications (3)

Publication Number Publication Date
DK177990D0 DK177990D0 (da) 1990-07-26
DK177990A true DK177990A (da) 1991-01-28
DK170777B1 DK170777B1 (da) 1996-01-15

Family

ID=11180349

Family Applications (1)

Application Number Title Priority Date Filing Date
DK177990A DK170777B1 (da) 1989-07-27 1990-07-26 Mono-(2-ammonium-2-hydroxymethyl-1,3-propandiol)(2R,cis)-1,2-epoxypropylphosphonat, fremgangsmåde til dets fremstilling og faste farmaceutiske præpar ater med indhold deraf

Country Status (19)

Country Link
US (1) US5162309A (da)
JP (1) JP2821803B2 (da)
AT (1) AT398204B (da)
BE (1) BE1002775A3 (da)
CA (1) CA2021809A1 (da)
CH (1) CH679669A5 (da)
DE (1) DE4023775C2 (da)
DK (1) DK170777B1 (da)
ES (1) ES2020790A6 (da)
FI (1) FI97232C (da)
FR (1) FR2650280B1 (da)
GB (1) GB2234245B (da)
GR (1) GR1000714B (da)
IE (1) IE63984B1 (da)
IT (1) IT1231013B (da)
LU (1) LU87774A1 (da)
NL (1) NL194504C (da)
PT (1) PT94816B (da)
SE (1) SE468769B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20021725A1 (it) 2002-08-01 2002-10-31 Zambon Spa Composizioni farmaceutiche ad attivita' antibiotica.
ES2244333B1 (es) * 2004-05-18 2006-08-01 Simbec Iberica, Sl Preparado farmaceutico oral de fosfomicina estable y apto para diabeticos.
EP1762573A1 (en) 2005-09-08 2007-03-14 Interquim, S.A. De C.V. A process for the preparation of fosfomycin salts
ES2385158B1 (es) * 2010-12-24 2013-05-28 Arafarma Group, S.A. Composición farmacéutica de fosfomicina
CN102351902A (zh) * 2011-08-12 2012-02-15 山西仟源制药股份有限公司 磷霉素单氨丁三醇的制备方法
CN102807586B (zh) 2012-08-31 2015-05-13 东北制药集团股份有限公司 磷霉素氨盐的制备方法
ITTO20130839A1 (it) * 2013-10-16 2015-04-17 C & G Farmaceutici S R L Composizione a base di fosfomicina trometamolo
DE102014218913A1 (de) * 2014-09-19 2016-03-24 Heraeus Medical Gmbh Verfahren zur Herstellung eines antibiotischen Polymehtylmethacrylat-Knochenzementpulvers und ein antibiotisches Polymethtylmethacrylat-Knochenzementpulver
WO2017111718A1 (en) 2015-12-25 2017-06-29 Yusuf Toktamiş Öğün The formulation comprising phosphomycine and ascorbic acid for the treatment of bacterial urinary system infections
CN108997425B (zh) * 2017-06-06 2020-11-13 湖南华纳大药厂手性药物有限公司 一种制备高含量磷霉素氨丁三醇的方法
CN108997424B (zh) * 2017-06-06 2020-11-13 湖南华纳大药厂手性药物有限公司 一种简捷制备磷霉素氨丁三醇的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3641063A (en) * 1968-01-22 1972-02-08 Merck & Co Inc Antibiotic purification process
US3914231A (en) * 1970-09-04 1975-10-21 Merck & Co Inc ({31 )(Cis-1,2-epoxypropyl)-phosphonic acid and salts thereof
IT1112282B (it) * 1978-07-19 1986-01-13 Zambon Spa Bis-(2-ammonio-2-idrossimetil-1,3-propandiolo)(2r-cis)-(3-metilossiranil)fosfonato
IT1124610B (it) * 1979-10-18 1986-05-07 Zambo Spa Mono(2-ammonio-2-idrossimetil-1,3-propandiolo) (2r-cis)-(o-metilossiranil)fosfonato

Also Published As

Publication number Publication date
ES2020790A6 (es) 1991-09-16
IE902628A1 (en) 1991-02-27
FI97232B (fi) 1996-07-31
SE9002501L (sv) 1991-01-28
US5162309A (en) 1992-11-10
BE1002775A3 (fr) 1991-06-04
GB2234245A (en) 1991-01-30
SE9002501D0 (sv) 1990-07-26
LU87774A1 (fr) 1990-12-11
IT8921340A0 (it) 1989-07-27
FR2650280A1 (fr) 1991-02-01
NL9001712A (nl) 1991-02-18
IT1231013B (it) 1991-11-08
GR900100570A (en) 1991-12-10
ATA156590A (de) 1994-02-15
FI97232C (fi) 1996-11-11
PT94816A (pt) 1991-04-18
PT94816B (pt) 1997-03-31
GR1000714B (el) 1992-11-23
SE468769B (sv) 1993-03-15
DK177990D0 (da) 1990-07-26
GB2234245B (en) 1992-10-14
DE4023775A1 (de) 1991-01-31
FI903760A0 (fi) 1990-07-27
CA2021809A1 (en) 1991-01-28
CH679669A5 (da) 1992-03-31
AT398204B (de) 1994-10-25
IE63984B1 (en) 1995-06-28
GB9016253D0 (en) 1990-09-12
DK170777B1 (da) 1996-01-15
JPH03101683A (ja) 1991-04-26
NL194504B (nl) 2002-02-01
FR2650280B1 (fr) 1992-02-07
NL194504C (nl) 2002-06-04
DE4023775C2 (de) 1999-07-22
JP2821803B2 (ja) 1998-11-05

Similar Documents

Publication Publication Date Title
DK165949C (da) 1,4-dihydropyridinderivater, fremgangsmaader til fremstilling deraf og farmaceutiske praeparater indeholdende forbindelserne
DK165112C (da) 2,2'-iminobisethanolderivater, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende disse
IT1232149B (it) Composizione farmaceutica contenente ranitidina, e metodo per prepararla
IT1231434B (it) Composizione farmaceutica endovenosa e procedimento per la sua preparazione.
NO812879L (no) Faste legemiddeltilberedninger inneholdende nifedipin og fremgangsmaate til deres fremstilling
NO880443L (no) N-heterosyklisk-n-(4-piperidyl)-amider og farmasoeytiske preparater og fremgangsmaater for bruk av slike forbindelser.
DK177990D0 (da) Mono-(2-ammonium-2-hydroxymethyl-1,3-propandiol)(2r,cis)-1,2-epoxypropylphosphonat, fremgangsmaade til fremstilling deraf og faste farmaceutiske praeparater indeholdende forbindelsen
DK462588A (da) 5-hydroxy-3-aminokromanforbindelser, fremgangsmaade til deres fremstilling, farmaceutiske praeparater indeholdende dem og fremgangsmaader til behandling dermed
DK127588A (da) Beta-aminoethylsubstituerede phenylforbindelser, farmaceutiske praeparater indeholdende samme og fremgangsmaader til fremstilling af saadanne forbindelser
NO871599L (no) Sammensetning for stimulering av kondrocytter og osteoblaster (osseinhydroksyapatittforbindelse), fremgangsmaate for fremstilling derav og farmasoeytiske preparater inneholdende sammensetningen.
DK415388A (da) Farmaceutiske praeparater indeholdende pyrimidinderivater og fremgangsmaade til fremstilling deraf
DK494088A (da) 4-oxo-3-quinolincarboxylsyrer, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende disse
DK92789D0 (da) Polypeptidderivater, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende disse
DK607388A (da) Polynukleotider, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende saadanne forbindelser
DK493988D0 (da) 4-oxo-3-quinolincarboxylsyrer, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende disse forbindelser
DK93385D0 (da) 3-amino-1-(4,5,6,7-tetrahydro-benzothiazolyl)-2-pyrazoliner, fremgangsmaade til fremstilling af disse forbindelser og farmaceutiske praeparater indeholdende disse forbindelser
DK300989A (da) Alaninderivater, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende saadanne forbindelser
DE3264718D1 (en) Piperazinoquinazoline antihypertensives, processes for preparing them, pharmaceutical compositions containing them, and immunogenic protein conjugates formed from them
DK185790D0 (da) 2,2-disubstituerede glycerol- og glycerolagtige forbindelser, praeparater indeholdende saadanne forbindelser og fremgangsmaader til anvendelse heraf
DK457386D0 (da) 4-substituerede catechol-derivater, fremgangsmaade til fremstillingderaf og farmaceutiske praeparater indeholdende saadanne derivater
DK258287A (da) 3-(hydroxymetyl)-isoquinolinderivater, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende dem
DK401088A (da) Cephalosporinforbindelse, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende den
DK163826C (da) 1,4-dihydro-3-carboxy-6,8-difluor-4-oxoquinolin-derivater, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende saadanne derivater
DK173287A (da) Perhydrothiazepin- og perhydroazepinderivater og fremgangsmaade til fremstilling deraf
DK163820C (da) 4-phenylpiperidinforbindelser, fremgangsmaade til fremstilling heraf og farmaceutisk praeparat indeholdende disse

Legal Events

Date Code Title Description
PBP Patent lapsed

Country of ref document: DK