PT882707E - Novos compostos trciclicos e composicoes medicamentosas contendo os mesmos - Google Patents

Novos compostos trciclicos e composicoes medicamentosas contendo os mesmos

Info

Publication number
PT882707E
PT882707E PT96942564T PT96942564T PT882707E PT 882707 E PT882707 E PT 882707E PT 96942564 T PT96942564 T PT 96942564T PT 96942564 T PT96942564 T PT 96942564T PT 882707 E PT882707 E PT 882707E
Authority
PT
Portugal
Prior art keywords
represents hydrogen
same
new
amino
compositions containing
Prior art date
Application number
PT96942564T
Other languages
English (en)
Portuguese (pt)
Inventor
Shiro Miyoshi
Kohei Ogawa
Original Assignee
Asahi Chemical Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Chemical Ind filed Critical Asahi Chemical Ind
Publication of PT882707E publication Critical patent/PT882707E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C307/04—Diamides of sulfuric acids
    • C07C307/10—Diamides of sulfuric acids having nitrogen atoms of the sulfamide groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
    • C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/76—Dibenzothiophenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18—Fluorenes; Hydrogenated fluorenes
PT96942564T 1996-01-10 1996-12-18 Novos compostos trciclicos e composicoes medicamentosas contendo os mesmos PT882707E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP257696 1996-01-10

Publications (1)

Publication Number Publication Date
PT882707E true PT882707E (pt) 2004-02-27

Family

ID=11533209

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96942564T PT882707E (pt) 1996-01-10 1996-12-18 Novos compostos trciclicos e composicoes medicamentosas contendo os mesmos

Country Status (14)

Country Link
US (4) US6037362A (ko)
EP (1) EP0882707B1 (ko)
JP (1) JP2000239255A (ko)
KR (1) KR100395280B1 (ko)
CN (2) CN1083831C (ko)
AT (1) ATE251608T1 (ko)
AU (1) AU715233B2 (ko)
CA (1) CA2242351C (ko)
DE (1) DE69630319T2 (ko)
ES (1) ES2208772T3 (ko)
HK (1) HK1017669A1 (ko)
NO (2) NO312159B1 (ko)
PT (1) PT882707E (ko)
WO (1) WO1997025311A1 (ko)

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KR20020031381A (ko) * 1999-07-09 2002-05-01 야마모토 카즈모토 삼환성 아미노 알코올 유도체의 제조법
CA2383757A1 (en) * 1999-09-03 2001-03-15 Masami Ogawa Processes for the preparation of tricyclic amino alcohol derivatives
US20030220329A1 (en) * 1999-09-17 2003-11-27 Duke University Method of improving beta-adrenergic receptor function
BR0014469A (pt) * 1999-10-04 2002-06-11 Asahi Chemical Ind Processo para melhorar a solubilidade de um derivado de amino álcool tricìclico, composição farmacêutica, processo para preparar a mesma, e, derivado de amino álcool tricìclico
CN1423637A (zh) * 1999-12-16 2003-06-11 旭化成株式会社 新的取代的三环化合物
EP1258253A1 (en) * 2000-01-28 2002-11-20 Asahi Kasei Kabushiki Kaisha Novel remedies with the use of beta3 agonist
DK1277736T3 (da) 2000-04-28 2007-10-01 Asahi Kasei Pharma Corp Hidtil ukendte bicykliske forbindelser
AU2001252575A1 (en) * 2000-04-28 2001-11-12 Asahi Kasei Kabushiki Kaisha Novel tricyclic compounds
WO2001083453A1 (fr) * 2000-04-28 2001-11-08 Asahi Kasei Kabushiki Kaisha Nouveaux composes tricycliques substitues
GB0010757D0 (en) * 2000-05-05 2000-06-28 Astrazeneca Ab Chemical compounds
IL156487A0 (en) * 2000-12-22 2004-01-04 Astrazeneca Ab Carbazole derivatives and their use as neuropeptide y5 receptor ligands
WO2002074306A1 (fr) * 2001-03-19 2002-09-26 Asahi Kasei Kabushiki Kaisha Remedes pour la steatose hepatique
GB0121941D0 (en) * 2001-09-11 2001-10-31 Astrazeneca Ab Chemical compounds
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KR100622461B1 (ko) 2001-10-25 2006-09-19 아사히 가세이 파마 가부시키가이샤 2환식 화합물
AU2003209527A1 (en) * 2002-02-27 2003-09-09 Pfizer Products Inc. Crystal forms of (r)-2-(2-(4-oxazol-4-yl-phenoxy)-ethylamino)-1-pyridin-3-yl-ethanol
US6864268B2 (en) 2002-02-27 2005-03-08 Pfizer Inc. β3 adrenergic receptor agonists
AU2003248352A1 (en) 2002-02-27 2003-09-09 Pfizer Products Inc. PROCESSES AND INTERMEDIATES USEFUL IN PREPARING Beta3-ADRENERGIC RECEPTOR AGONISTS
EP1424079A1 (en) * 2002-11-27 2004-06-02 Boehringer Ingelheim International GmbH Combination of a beta-3-receptor agonist and of a reuptake inhibitor of serotonin and/or norepinephrine
WO2004072016A1 (ja) * 2003-02-14 2004-08-26 Kissei Pharmaceutical Co., Ltd. アミノアルコール誘導体、それを含有する医薬組成物およびそれらの用途
JP4644601B2 (ja) * 2003-10-24 2011-03-02 キッセイ薬品工業株式会社 アミノアルコール誘導体、それを含有する医薬組成物およびそれらの用途
US8501994B2 (en) 2007-08-28 2013-08-06 Sunovion Pharmaceuticals Inc. Acetamide stereoisomer
US7718822B2 (en) 2007-08-28 2010-05-18 Sepracor Inc. Carbamate Stereoisomer
CA2740772A1 (en) 2008-10-09 2010-04-15 Asahi Kasei Pharma Corporation Indazole compounds
CN102171191A (zh) 2008-10-09 2011-08-31 旭化成制药株式会社 吲唑衍生物
US20100222404A1 (en) * 2008-11-04 2010-09-02 Asahi Kasei Pharma Corporation Indazole derivative dihydrochloride
WO2011040510A1 (ja) * 2009-09-30 2011-04-07 旭化成ファーマ株式会社 インダゾール類縁体
WO2012032546A2 (en) * 2010-09-08 2012-03-15 Cadila Healthcare Limited Process for the preparation of salmeterol and its intermediates
ES2394349B1 (es) 2012-08-29 2013-11-04 Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii Uso de agonistas selectivos de receptores beta-3 adrenérgicos para el tratamiento de hipertensión pulmonar
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Also Published As

Publication number Publication date
EP0882707A1 (en) 1998-12-09
CN1209119A (zh) 1999-02-24
KR100395280B1 (ko) 2004-06-04
AU1170897A (en) 1997-08-01
NO20012876D0 (no) 2001-06-11
CN1083831C (zh) 2002-05-01
HK1017669A1 (en) 1999-11-26
NO983197L (no) 1998-09-10
EP0882707A4 (en) 2001-04-11
KR19990077162A (ko) 1999-10-25
US20030139475A1 (en) 2003-07-24
US6037362A (en) 2000-03-14
NO312159B1 (no) 2002-04-02
AU715233B2 (en) 2000-01-20
DE69630319T2 (de) 2004-07-29
WO1997025311A1 (fr) 1997-07-17
CA2242351C (en) 2003-03-11
DE69630319D1 (de) 2003-11-13
NO20012876L (no) 1998-09-10
CA2242351A1 (en) 1997-07-17
CN1295064A (zh) 2001-05-16
ATE251608T1 (de) 2003-10-15
ES2208772T3 (es) 2004-06-16
US6545053B1 (en) 2003-04-08
EP0882707B1 (en) 2003-10-08
US6187809B1 (en) 2001-02-13
JP2000239255A (ja) 2000-09-05

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