FR2332010A1 - Amino-alcool heterocyclique, son sel et son procede de preparation - Google Patents

Amino-alcool heterocyclique, son sel et son procede de preparation

Info

Publication number
FR2332010A1
FR2332010A1 FR7535217A FR7535217A FR2332010A1 FR 2332010 A1 FR2332010 A1 FR 2332010A1 FR 7535217 A FR7535217 A FR 7535217A FR 7535217 A FR7535217 A FR 7535217A FR 2332010 A1 FR2332010 A1 FR 2332010A1
Authority
FR
France
Prior art keywords
alcohol
salt
preparation process
heterocyclic amino
heterocyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7535217A
Other languages
English (en)
Other versions
FR2332010B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Continental Pharma Inc
Original Assignee
Continental Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Continental Pharma Inc filed Critical Continental Pharma Inc
Priority to FR7535217A priority Critical patent/FR2332010A1/fr
Priority to SE7612554A priority patent/SE434744B/xx
Priority to DE2651572A priority patent/DE2651572C2/de
Priority to FI763265A priority patent/FI763265A/fi
Priority to MX793376A priority patent/MX155809A/es
Priority to PT65853A priority patent/PT65853B/fr
Priority to NLAANVRAGE7612794,A priority patent/NL180936C/xx
Priority to ES453389A priority patent/ES453389A1/es
Priority to DK517076A priority patent/DK151330C/da
Priority to MX765135U priority patent/MX4881E/es
Priority to AT854376A priority patent/AT355566B/de
Priority to IL50932A priority patent/IL50932A/xx
Priority to NO763917A priority patent/NO147748C/no
Priority to GR52209A priority patent/GR62012B/el
Priority to CH1454276A priority patent/CH623321A5/fr
Priority to ZA766907A priority patent/ZA766907B/xx
Priority to NZ182665A priority patent/NZ182665A/xx
Priority to IE2541/76A priority patent/IE44265B1/en
Priority to AU19779/76A priority patent/AU510315B2/en
Priority to CA266,041A priority patent/CA1094088A/fr
Priority to BE172486A priority patent/BE848496A/fr
Priority to GB48127/76A priority patent/GB1565080A/en
Priority to JP13785976A priority patent/JPS5297952A/ja
Publication of FR2332010A1 publication Critical patent/FR2332010A1/fr
Priority to AT861678A priority patent/AT363468B/de
Application granted granted Critical
Publication of FR2332010B1 publication Critical patent/FR2332010B1/fr
Priority to CH167280A priority patent/CH622770A5/fr
Priority to JP57002388A priority patent/JPS6017778B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/06—Six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
    • C07D339/08—Six-membered rings
FR7535217A 1975-11-18 1975-11-18 Amino-alcool heterocyclique, son sel et son procede de preparation Granted FR2332010A1 (fr)

Priority Applications (26)

Application Number Priority Date Filing Date Title
FR7535217A FR2332010A1 (fr) 1975-11-18 1975-11-18 Amino-alcool heterocyclique, son sel et son procede de preparation
SE7612554A SE434744B (sv) 1975-11-18 1976-11-11 Forfarande for framstellning av aminoalkoholderivat
DE2651572A DE2651572C2 (de) 1975-11-18 1976-11-12 Aminoalkohole, Verfahren zu deren Herstellung sowie diese enthaltende pharmazeutische Zubereitungen
FI763265A FI763265A (fr) 1975-11-18 1976-11-15
PT65853A PT65853B (fr) 1975-11-18 1976-11-17 Procede de preparation des derives d'amino-alcools
NLAANVRAGE7612794,A NL180936C (nl) 1975-11-18 1976-11-17 Werkwijze voor het bereiden van aminoalcoholverbindingen alsmede werkwijze voor het bereiden van farmacologische preparaten met ten minste een dergelijke aminoalcoholverbinding als werkzame stof.
ES453389A ES453389A1 (es) 1975-11-18 1976-11-17 Procedimiento para la preparacion de derivados de amino- alcoholes.
DK517076A DK151330C (da) 1975-11-18 1976-11-17 Analogifremgangsmaade til fremstilling af aminoalkoholderivater eller farmaceutiske acceptable salte deraf
MX765135U MX4881E (es) 1975-11-18 1976-11-17 Procedimiento para preparar derivados de aminoalcoholes heterociclicos
AT854376A AT355566B (de) 1975-11-18 1976-11-17 Verfahren zum herstellen von neuen amino- alkohol-derivaten
IL50932A IL50932A (en) 1975-11-18 1976-11-17 Carbo(hetero)bicyclic ethanolamine derivatives,process for their preparation and pharmaceutical compositions containing them
NO763917A NO147748C (no) 1975-11-18 1976-11-17 Analogifremgangsmaate ved fremstilling av terapeutisk aktive aminoalkoholderivater
MX793376A MX155809A (es) 1975-11-18 1976-11-17 Procedimiento para preparar derivados de amino-alcoholes heterociclicos
JP13785976A JPS5297952A (en) 1975-11-18 1976-11-18 Aminoalcohol derivatives and preparation thereof
ZA766907A ZA766907B (en) 1975-11-18 1976-11-18 Heterocyclic amino-alcohol derivatives and their preparation
NZ182665A NZ182665A (en) 1975-11-18 1976-11-18 Amine derivatives and pharmaceutical compositions
GR52209A GR62012B (en) 1975-11-18 1976-11-18 Preparation process of heterocyclic amino-alcools
AU19779/76A AU510315B2 (en) 1975-11-18 1976-11-18 Heterocyclic amino alcohol derivatives
CA266,041A CA1094088A (fr) 1975-11-18 1976-11-18 Obtention de derives d'amino-alcools heterocycliques
BE172486A BE848496A (fr) 1975-11-18 1976-11-18 Derives d'amino-alcools, leur preparation et utilisation, ainsi que compositions contenant ces derives.
GB48127/76A GB1565080A (en) 1975-11-18 1976-11-18 Amino-alcohol derivatives and their preparation
CH1454276A CH623321A5 (en) 1975-11-18 1976-11-18 Process for the preparation of heterocyclic aminoalcohol derivatives
IE2541/76A IE44265B1 (en) 1975-11-18 1976-11-18 Amino-alcohol derivatives and their preparation
AT861678A AT363468B (de) 1975-11-18 1978-12-01 Verfahren zum herstellen von neuen aminoalkohol- -derivaten
CH167280A CH622770A5 (en) 1975-11-18 1980-03-03 Process for the preparation of heterocyclic aminoalcohol derivatives
JP57002388A JPS6017778B2 (ja) 1975-11-18 1982-01-12 アミノアルコ−ル誘導体およびその塩，並びにこれらの製造方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7535217A FR2332010A1 (fr) 1975-11-18 1975-11-18 Amino-alcool heterocyclique, son sel et son procede de preparation

Publications (2)

Publication Number Publication Date
FR2332010A1 true FR2332010A1 (fr) 1977-06-17
FR2332010B1 FR2332010B1 (fr) 1979-06-29

Family

ID=9162563

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7535217A Granted FR2332010A1 (fr) 1975-11-18 1975-11-18 Amino-alcool heterocyclique, son sel et son procede de preparation

Country Status (21)

Country Link
JP (2) JPS5297952A (fr)
AT (1) AT355566B (fr)
AU (1) AU510315B2 (fr)
BE (1) BE848496A (fr)
CA (1) CA1094088A (fr)
CH (2) CH623321A5 (fr)
DE (1) DE2651572C2 (fr)
DK (1) DK151330C (fr)
ES (1) ES453389A1 (fr)
FI (1) FI763265A (fr)
FR (1) FR2332010A1 (fr)
GB (1) GB1565080A (fr)
GR (1) GR62012B (fr)
IE (1) IE44265B1 (fr)
IL (1) IL50932A (fr)
MX (1) MX4881E (fr)
NL (1) NL180936C (fr)
NZ (1) NZ182665A (fr)
PT (1) PT65853B (fr)
SE (1) SE434744B (fr)
ZA (1) ZA766907B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2512817A1 (fr) * 1981-09-17 1983-03-18 Roussel Uclaf Nouveaux derives de l'aminomethyl 1h-indole-4-methanol et leurs sels, leur procede de preparation, leur application a titre de medicaments, les compositions les renfermant et leurs intermediaires de preparation

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4622399A (en) * 1983-06-30 1986-11-11 American Home Products Corporation Bicyclo-heterocyclic nitrogen substituted aminoethanol derivatives
US4562200A (en) * 1983-06-30 1985-12-31 American Home Products Corporation 5(Indolyl) and 5(2,3-dihydroindolyl) substituted aminoethanols and their use as anti-hypertensives
US4521606A (en) * 1983-06-30 1985-06-04 American Home Products Corp. 5-Indolyl substituted aminoethanols
ATE194982T1 (de) 1992-04-24 2000-08-15 Takeda Chemical Industries Ltd Benzoxazepin-derivate als cholinesterase- inhibitoren
US5705515A (en) * 1994-04-26 1998-01-06 Merck & Co., Inc. Substituted sulfonamides as selective β-3 agonists for the treatment of diabetes and obesity
US5541197A (en) * 1994-04-26 1996-07-30 Merck & Co., Inc. Substituted sulfonamides as selective β3 agonists for the treatment of diabetes and obesity
US5561142A (en) * 1994-04-26 1996-10-01 Merck & Co., Inc. Substituted sulfonamides as selective β3 agonists for the treatment of diabetes and obesity
US5656661A (en) * 1994-07-27 1997-08-12 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5684002A (en) * 1994-09-07 1997-11-04 The Procter & Gamble Company Dihydorbenzofuran and related compounds useful as anti-inflammatory agents
EP0882707B1 (fr) 1996-01-10 2003-10-08 Asahi Kasei Kabushiki Kaisha Nouveaux composes tricycliques et compositions medicamenteuses contenant ces composes
US5672620A (en) * 1996-02-01 1997-09-30 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5684031A (en) * 1996-02-01 1997-11-04 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
FR2758820B1 (fr) * 1997-01-30 1999-02-26 Synthelabo Derives de alpha-azacyclomethyl-benzofurane, leur preparation et leur application en therapeutique
AU6218598A (en) * 1997-01-30 1998-08-25 Synthelabo Alpha-azacyclomethyl benzothiophene and alpha-azacyclomethyl benzofurane derivatives, preparation and therapeutic application
US6172099B1 (en) 1997-07-03 2001-01-09 Asahi Kasei Kogyo Kabushiki Kaisha Tricyclic compounds having saturated rings and medicinal compositions containing the same
ES2287120T3 (es) 2000-04-28 2007-12-16 Asahi Kasei Pharma Corporation Nuevos compuestos biciclicos.
DK1447400T3 (da) 2001-10-25 2008-12-08 Asahi Kasei Pharma Corp Bicyklisk forbindelse
AU2009301798B2 (en) 2008-10-09 2012-03-01 Asahi Kasei Pharma Corporation Indazole compound
CA2737349A1 (fr) 2008-10-09 2010-04-09 Asahi Kasei Pharma Corporation Derives d'indazole

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1013224A (en) * 1962-06-21 1965-12-15 Ici Ltd Heterocyclic aminoethanols
US3255249A (en) * 1963-04-26 1966-06-07 Ici Ltd 2-branched lower alkyl-amino-1-(indan-, hydrogenated indan- and hydrogenated naphth-2-yl) lower alkanols
CH442302A (de) * 1964-04-17 1967-08-31 Sandoz Ag Verfahren zur Herstellung eines neuen Indolderivates
FR2138488A1 (en) * 1971-05-27 1973-01-05 Lipha 1-(5-indanyl)-omega-aminoalkanes - with tranquillizing activity

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2512817A1 (fr) * 1981-09-17 1983-03-18 Roussel Uclaf Nouveaux derives de l'aminomethyl 1h-indole-4-methanol et leurs sels, leur procede de preparation, leur application a titre de medicaments, les compositions les renfermant et leurs intermediaires de preparation
EP0076713A1 (fr) * 1981-09-17 1983-04-13 Roussel-Uclaf Nouveaux dérivés de l'aminométhyl 1H-indole 4-méthanol et leurs sels, leur procédé et les intermédiaires de préparation, leur application à titre de médicaments, les compositions les renfermant

Also Published As

Publication number Publication date
JPS6017778B2 (ja) 1985-05-07
IE44265L (en) 1977-05-18
DK151330C (da) 1988-04-25
PT65853B (fr) 1978-05-15
NL180936C (nl) 1987-05-18
BE848496A (fr) 1977-05-18
ZA766907B (en) 1977-10-26
NL180936B (nl) 1986-12-16
CA1094088A (fr) 1981-01-20
CH623321A5 (en) 1981-05-29
GB1565080A (en) 1980-04-16
FI763265A (fr) 1977-05-19
DK151330B (da) 1987-11-23
CH622770A5 (en) 1981-04-30
DE2651572C2 (de) 1982-05-19
PT65853A (fr) 1976-12-01
DK517076A (da) 1977-05-19
IL50932A0 (en) 1977-01-31
DE2651572A1 (de) 1977-06-08
IE44265B1 (en) 1981-09-23
JPS57145843A (en) 1982-09-09
ATA854376A (de) 1979-08-15
AT355566B (de) 1980-03-10
MX4881E (es) 1982-11-30
FR2332010B1 (fr) 1979-06-29
AU510315B2 (en) 1980-06-19
IL50932A (en) 1984-01-31
JPS5297952A (en) 1977-08-17
NZ182665A (en) 1978-11-13
SE434744B (sv) 1984-08-13
NL7612794A (nl) 1977-05-23
SE7612554L (sv) 1977-05-19
ES453389A1 (es) 1977-11-16
GR62012B (en) 1979-02-15
AU1977976A (en) 1978-05-25
JPS63435B2 (fr) 1988-01-07

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