PT882707E - Novos compostos trciclicos e composicoes medicamentosas contendo os mesmos - Google Patents
Novos compostos trciclicos e composicoes medicamentosas contendo os mesmosInfo
- Publication number
- PT882707E PT882707E PT96942564T PT96942564T PT882707E PT 882707 E PT882707 E PT 882707E PT 96942564 T PT96942564 T PT 96942564T PT 96942564 T PT96942564 T PT 96942564T PT 882707 E PT882707 E PT 882707E
- Authority
- PT
- Portugal
- Prior art keywords
- represents hydrogen
- same
- new
- amino
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C307/00—Amides of sulfuric acids, i.e. compounds having singly-bound oxygen atoms of sulfate groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C307/04—Diamides of sulfuric acids
- C07C307/10—Diamides of sulfuric acids having nitrogen atoms of the sulfamide groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/76—Dibenzothiophenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Indole Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP257696 | 1996-01-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT882707E true PT882707E (pt) | 2004-02-27 |
Family
ID=11533209
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT96942564T PT882707E (pt) | 1996-01-10 | 1996-12-18 | Novos compostos trciclicos e composicoes medicamentosas contendo os mesmos |
Country Status (14)
Country | Link |
---|---|
US (4) | US6037362A (pt) |
EP (1) | EP0882707B1 (pt) |
JP (1) | JP2000239255A (pt) |
KR (1) | KR100395280B1 (pt) |
CN (2) | CN1083831C (pt) |
AT (1) | ATE251608T1 (pt) |
AU (1) | AU715233B2 (pt) |
CA (1) | CA2242351C (pt) |
DE (1) | DE69630319T2 (pt) |
ES (1) | ES2208772T3 (pt) |
HK (1) | HK1017669A1 (pt) |
NO (2) | NO312159B1 (pt) |
PT (1) | PT882707E (pt) |
WO (1) | WO1997025311A1 (pt) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6025355A (en) | 1997-05-19 | 2000-02-15 | Cambridge Neuroscience, Inc. | Pharmaceutically active compounds and methods of use |
US6040344A (en) * | 1996-11-11 | 2000-03-21 | Sepracor Inc. | Formoterol process |
ES2178015T3 (es) * | 1996-11-11 | 2002-12-16 | Sepracor Inc | Procedimiento de preparacion de isomeros de formoterol opticamente puros. |
CA2296104A1 (en) * | 1997-07-03 | 1999-01-14 | Asahi Kasei Kogyo Kabushiki Kaisha | Novel tricyclic compounds having saturated rings and medicinal compositions containing the same |
US6495546B1 (en) * | 1998-04-06 | 2002-12-17 | Fujisawa Pharmaceutical Co., Ltd. | Propanolamine derivatives |
CA2350062A1 (en) * | 1998-11-11 | 2000-05-18 | Smithkline Beecham P.L.C. | Combinations comprising a beta-agonist and a further antidiabetic agent |
US20030073644A1 (en) * | 1998-11-11 | 2003-04-17 | Smithkline Beecham P.L.C. | Combinations comprising a beta-agonist and a further antidiabetic agent |
CN1333760A (zh) * | 1998-12-15 | 2002-01-30 | 旭化成株式会社 | 新杂环化合物以及含此化合物的药用组合物 |
TW519537B (en) * | 1999-03-26 | 2003-02-01 | Asahi Chemical Ind | Process for the preparation of tricylic amino-alcohol derivatives |
CN1349502A (zh) * | 1999-04-01 | 2002-05-15 | 旭化成株式会社 | 经由叠氮化物制备三环氨基-醇衍生物的新方法 |
WO2001004092A1 (fr) * | 1999-07-09 | 2001-01-18 | Asahi Kasei Kabushiki Kaisha | Procede de preparation de derives d'alcools amines tricycliques |
BR0013717A (pt) | 1999-09-03 | 2002-07-02 | Asahi Chemical Ind | Processo para a preparação de um composto, para a preparação de qualquer um dos isÈmeros ópticos de um halohidrina, isÈmero óptico, composto, e, processo para a preparação de um derivado de alfa-clorofenona |
US20030220329A1 (en) * | 1999-09-17 | 2003-11-27 | Duke University | Method of improving beta-adrenergic receptor function |
AU7447900A (en) * | 1999-10-04 | 2001-05-10 | Asahi Kasei Kabushiki Kaisha | Method for improving the solubility of tricyclic amino alcohol derivatives |
CN1423637A (zh) * | 1999-12-16 | 2003-06-11 | 旭化成株式会社 | 新的取代的三环化合物 |
EP1258253A1 (en) * | 2000-01-28 | 2002-11-20 | Asahi Kasei Kabushiki Kaisha | Novel remedies with the use of beta3 agonist |
AU2001252573A1 (en) * | 2000-04-28 | 2001-11-12 | Asahi Kasei Kabushiki Kaisha | Novel substituted tricyclic compounds |
DK1277736T3 (da) * | 2000-04-28 | 2007-10-01 | Asahi Kasei Pharma Corp | Hidtil ukendte bicykliske forbindelser |
AU2001252575A1 (en) * | 2000-04-28 | 2001-11-12 | Asahi Kasei Kabushiki Kaisha | Novel tricyclic compounds |
GB0010757D0 (en) | 2000-05-05 | 2000-06-28 | Astrazeneca Ab | Chemical compounds |
MXPA03005648A (es) * | 2000-12-22 | 2003-10-06 | Astrazeneca Ab | Derivados de carbazol y su uso, como ligandos de receptor del neuropeptido y5. |
JPWO2002074306A1 (ja) * | 2001-03-19 | 2004-07-08 | 旭化成ファーマ株式会社 | 脂肪肝治療薬 |
GB0121941D0 (en) * | 2001-09-11 | 2001-10-31 | Astrazeneca Ab | Chemical compounds |
KR100816527B1 (ko) * | 2001-09-12 | 2008-04-10 | 한국화학연구원 | 페닐테트라졸 유도체로 치환된 β-아미노알코올 화합물 |
WO2003035620A1 (fr) | 2001-10-25 | 2003-05-01 | Asahi Kasei Pharma Corporation | Compose bicyclique |
US6864268B2 (en) | 2002-02-27 | 2005-03-08 | Pfizer Inc. | β3 adrenergic receptor agonists |
WO2003072573A1 (en) * | 2002-02-27 | 2003-09-04 | Pfizer Products Inc. | Crystal forms of (r)-2-(2-(4-oxazol-4-yl-phenoxy)-ethylamino)-1-pyridin-3-yl-ethanol |
MXPA04008298A (es) | 2002-02-27 | 2004-11-26 | Pfizer Prod Inc | Procesos e intermedios utiles en la preparacion de agonistas de receptor beta-3 adrenergico. |
EP1424079A1 (en) * | 2002-11-27 | 2004-06-02 | Boehringer Ingelheim International GmbH | Combination of a beta-3-receptor agonist and of a reuptake inhibitor of serotonin and/or norepinephrine |
EP1593666B1 (en) | 2003-02-14 | 2008-07-02 | Kissei Pharmaceutical Co., Ltd. | Amino alcohol derivatives, pharmaceutical compositions containing the same, and use thereof |
US7417169B2 (en) * | 2003-10-24 | 2008-08-26 | Kissei Pharmaceutical Co., Ltd. | Amino alcohol derivatives, medicinal composition containing the same, and use of these |
US7718822B2 (en) | 2007-08-28 | 2010-05-18 | Sepracor Inc. | Carbamate Stereoisomer |
US8501994B2 (en) | 2007-08-28 | 2013-08-06 | Sunovion Pharmaceuticals Inc. | Acetamide stereoisomer |
EP2345644A4 (en) | 2008-10-09 | 2012-03-21 | Asahi Kasei Pharma Corp | INDAZOLE COMPOUND |
KR20110050733A (ko) | 2008-10-09 | 2011-05-16 | 아사히 가세이 파마 가부시키가이샤 | 인다졸 유도체 |
US20100222404A1 (en) * | 2008-11-04 | 2010-09-02 | Asahi Kasei Pharma Corporation | Indazole derivative dihydrochloride |
US20120225909A1 (en) * | 2009-09-30 | 2012-09-06 | Asahi Kasei Pharma Corporation | Indazole analog |
WO2012032546A2 (en) * | 2010-09-08 | 2012-03-15 | Cadila Healthcare Limited | Process for the preparation of salmeterol and its intermediates |
ES2394349B1 (es) | 2012-08-29 | 2013-11-04 | Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii | Uso de agonistas selectivos de receptores beta-3 adrenérgicos para el tratamiento de hipertensión pulmonar |
US9784726B2 (en) | 2013-01-08 | 2017-10-10 | Atrogi Ab | Screening method, a kit, a method of treatment and a compound for use in a method of treatment |
WO2015003146A1 (en) | 2013-07-03 | 2015-01-08 | Georgetown University | Boronic acid derivatives of resveratrol for activating deacetylase enzymes |
US11053255B2 (en) | 2015-06-22 | 2021-07-06 | Georgetown University | Synthesis of mahanine and related compounds |
GB201714745D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
GB201714740D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
GB201714734D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
GB201714736D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
GB202205895D0 (en) | 2022-04-22 | 2022-06-08 | Atrogi Ab | New medical uses |
CN115656390B (zh) * | 2022-12-08 | 2023-03-28 | 成都苑东生物制药股份有限公司 | 一种氨酚羟考酮缓释片的含量测定方法 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL33573A (en) * | 1968-12-30 | 1973-10-25 | Richardson Merrell Inc | Bis-basic ethers and thioethers of fluorenone,fluorenol and fluorene |
GB1521089A (en) * | 1975-11-12 | 1978-08-09 | Valeas Srl | Aminoethanol derivatives |
FR2332010A1 (fr) * | 1975-11-18 | 1977-06-17 | Continental Pharma | Amino-alcool heterocyclique, son sel et son procede de preparation |
DK31578A (da) * | 1977-02-03 | 1978-08-04 | Allen & Hanburys Ltd | Fremgangsmaade til fremstilling af benzenderivater |
JPS5473751A (en) * | 1977-10-12 | 1979-06-13 | Yamanouchi Pharmaceut Co Ltd | Phenyl ethanolamine derivatives and their preparation |
CA1147342A (en) * | 1977-10-12 | 1983-05-31 | Kazuo Imai | Process of producing novel phenylethanolamine derivatives |
JPS5553262A (en) * | 1978-10-17 | 1980-04-18 | Yamanouchi Pharmaceut Co Ltd | Phenylethanolamine derivative |
EP0023385B1 (en) * | 1979-06-16 | 1982-12-15 | Beecham Group Plc | Ethanamine derivatives, their preparation and use in pharmaceutical compositions |
JPS5950671B2 (ja) * | 1982-08-26 | 1984-12-10 | 山之内製薬株式会社 | フェニルエタノ−ルアミン誘導体およびその製造法 |
GB8419797D0 (en) * | 1984-08-03 | 1984-09-05 | Beecham Group Plc | Compounds |
US5061727A (en) * | 1990-05-04 | 1991-10-29 | American Cyanamid Company | Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles |
AU675536B2 (en) * | 1993-06-14 | 1997-02-06 | Pfizer Inc. | Secondary amines as antidiabetic and antiobesity agents |
US5776983A (en) * | 1993-12-21 | 1998-07-07 | Bristol-Myers Squibb Company | Catecholamine surrogates useful as β3 agonists |
IL113410A (en) * | 1994-04-26 | 1999-11-30 | Merck & Co Inc | Substituted sulfonamides having an asymmetric center and pharmaceutical compositions containing them |
JPH08165276A (ja) * | 1994-12-14 | 1996-06-25 | Dainippon Pharmaceut Co Ltd | 2−アルキルアミノ−1−フェニルエタノール誘導体 |
-
1996
- 1996-12-18 AT AT96942564T patent/ATE251608T1/de not_active IP Right Cessation
- 1996-12-18 CN CN96180079A patent/CN1083831C/zh not_active Expired - Fee Related
- 1996-12-18 PT PT96942564T patent/PT882707E/pt unknown
- 1996-12-18 CA CA002242351A patent/CA2242351C/en not_active Expired - Fee Related
- 1996-12-18 WO PCT/JP1996/003689 patent/WO1997025311A1/ja active IP Right Grant
- 1996-12-18 KR KR10-1998-0705300A patent/KR100395280B1/ko not_active IP Right Cessation
- 1996-12-18 DE DE69630319T patent/DE69630319T2/de not_active Expired - Lifetime
- 1996-12-18 US US09/101,232 patent/US6037362A/en not_active Expired - Fee Related
- 1996-12-18 AU AU11708/97A patent/AU715233B2/en not_active Ceased
- 1996-12-18 ES ES96942564T patent/ES2208772T3/es not_active Expired - Lifetime
- 1996-12-18 EP EP96942564A patent/EP0882707B1/en not_active Expired - Lifetime
-
1998
- 1998-07-10 NO NO19983197A patent/NO312159B1/no not_active IP Right Cessation
-
1999
- 1999-07-05 HK HK99102818A patent/HK1017669A1/xx not_active IP Right Cessation
- 1999-12-28 US US09/472,937 patent/US6187809B1/en not_active Expired - Fee Related
-
2000
- 2000-02-23 JP JP2000045460A patent/JP2000239255A/ja not_active Withdrawn
- 2000-11-02 CN CN00131988A patent/CN1295064A/zh active Pending
- 2000-11-16 US US09/713,202 patent/US6545053B1/en not_active Expired - Fee Related
-
2001
- 2001-06-11 NO NO20012876A patent/NO20012876D0/no not_active Application Discontinuation
-
2002
- 2002-09-30 US US10/259,462 patent/US20030139475A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
HK1017669A1 (en) | 1999-11-26 |
JP2000239255A (ja) | 2000-09-05 |
KR19990077162A (ko) | 1999-10-25 |
US6545053B1 (en) | 2003-04-08 |
DE69630319T2 (de) | 2004-07-29 |
EP0882707A4 (en) | 2001-04-11 |
US6037362A (en) | 2000-03-14 |
US6187809B1 (en) | 2001-02-13 |
AU1170897A (en) | 1997-08-01 |
NO20012876D0 (no) | 2001-06-11 |
ATE251608T1 (de) | 2003-10-15 |
AU715233B2 (en) | 2000-01-20 |
CA2242351C (en) | 2003-03-11 |
US20030139475A1 (en) | 2003-07-24 |
EP0882707A1 (en) | 1998-12-09 |
NO983197L (no) | 1998-09-10 |
CN1209119A (zh) | 1999-02-24 |
KR100395280B1 (ko) | 2004-06-04 |
NO20012876L (no) | 1998-09-10 |
WO1997025311A1 (fr) | 1997-07-17 |
CN1295064A (zh) | 2001-05-16 |
CN1083831C (zh) | 2002-05-01 |
NO312159B1 (no) | 2002-04-02 |
DE69630319D1 (de) | 2003-11-13 |
ES2208772T3 (es) | 2004-06-16 |
CA2242351A1 (en) | 1997-07-17 |
EP0882707B1 (en) | 2003-10-08 |
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