ATE1994T1 - Aethanamin-derivate, ihre herstellung und verwendung in pharmazeutischen zusammensetzungen. - Google Patents
Aethanamin-derivate, ihre herstellung und verwendung in pharmazeutischen zusammensetzungen.Info
- Publication number
- ATE1994T1 ATE1994T1 AT80301927T AT80301927T ATE1994T1 AT E1994 T1 ATE1994 T1 AT E1994T1 AT 80301927 T AT80301927 T AT 80301927T AT 80301927 T AT80301927 T AT 80301927T AT E1994 T1 ATE1994 T1 AT E1994T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- hydrogen
- atom
- chlorine
- methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/20—Free hydroxyl or mercaptan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/13—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups
- C07C205/17—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups bound to acyclic carbon atoms and hydroxy groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
- C07C205/32—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups bound to acyclic carbon atoms and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/48—Preparation of compounds having groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/48—Preparation of compounds having groups
- C07C41/50—Preparation of compounds having groups by reactions producing groups
- C07C41/56—Preparation of compounds having groups by reactions producing groups by condensation of aldehydes, paraformaldehyde, or ketones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/30—Compounds having groups
- C07C43/315—Compounds having groups containing oxygen atoms singly bound to carbon atoms not being acetal carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/42—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrolysis
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7921038 | 1979-06-16 | ||
| EP80301927A EP0023385B1 (de) | 1979-06-16 | 1980-06-09 | Äthanamin-Derivate, ihre Herstellung und Verwendung in pharmazeutischen Zusammensetzungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE1994T1 true ATE1994T1 (de) | 1982-12-15 |
Family
ID=10505899
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT80301927T ATE1994T1 (de) | 1979-06-16 | 1980-06-09 | Aethanamin-derivate, ihre herstellung und verwendung in pharmazeutischen zusammensetzungen. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US4338333A (de) |
| EP (1) | EP0023385B1 (de) |
| JP (1) | JPS565444A (de) |
| AT (1) | ATE1994T1 (de) |
| AU (1) | AU533432B2 (de) |
| CA (1) | CA1150297A (de) |
| DE (1) | DE3061334D1 (de) |
| DK (1) | DK256580A (de) |
| ES (2) | ES492489A0 (de) |
| IE (1) | IE49908B1 (de) |
| IL (1) | IL60288A0 (de) |
| MY (1) | MY8500997A (de) |
| NZ (1) | NZ193988A (de) |
| ZA (1) | ZA803576B (de) |
Families Citing this family (87)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56112903A (en) * | 1980-02-12 | 1981-09-05 | Shin Etsu Chem Co Ltd | Polymerization of vinyl monomer |
| DE3264364D1 (en) * | 1981-03-06 | 1985-08-01 | Beecham Group Plc | Arylethanol amine derivatives, their preparation and use in pharmaceutical compositions |
| EP0070134B1 (de) * | 1981-07-11 | 1985-11-13 | Beecham Group Plc | Sekundäre Phenylethanolamine und deren Verwendung in der Pharmazie |
| DE3271132D1 (en) * | 1981-07-11 | 1986-06-19 | Beecham Group Plc | Secondary phenylethanol amines, processes for their preparation and their pharmaceutical application |
| US4652681A (en) * | 1982-04-15 | 1987-03-24 | Drug Science Foundation | Aminoalkoxy derivatives of propranolol for immunoassay applications |
| CA1219865A (en) * | 1982-05-14 | 1987-03-31 | Leo Alig | Aziridine phenethanolamine derivatives |
| DE3368258D1 (en) * | 1982-07-16 | 1987-01-22 | Beecham Group Plc | 2-aminoethyl ether derivatives, processes for their preparation and pharmaceutical compositions containing them |
| CA1258454A (en) * | 1982-08-10 | 1989-08-15 | Leo Alig | Phenethanolamines |
| EP0118489A1 (de) * | 1982-08-27 | 1984-09-19 | Beecham Group Plc | Sekundäre arylethanolamine |
| US4690951A (en) * | 1983-01-31 | 1987-09-01 | Eli Lilly And Company | Growth promotion |
| US4849453A (en) * | 1983-01-31 | 1989-07-18 | Eli Lilly And Company | Growth promotion |
| GB8310556D0 (en) * | 1983-04-19 | 1983-05-25 | Beecham Group Plc | Compounds |
| DE3462789D1 (en) * | 1983-08-17 | 1987-04-30 | Beecham Group Plc | 2-phenylethylamine derivatives |
| EP0142102B1 (de) * | 1983-11-04 | 1987-09-23 | Beecham Group Plc | Tertiäre Amine |
| JPS60233103A (ja) * | 1984-05-07 | 1985-11-19 | Shin Etsu Chem Co Ltd | ビニル系単量体の重合方法 |
| GB8415377D0 (en) * | 1984-06-15 | 1984-07-18 | Beecham Group Plc | Compounds |
| IN165525B (de) | 1984-07-23 | 1989-11-04 | Shinetsu Chemical Co | |
| GB8420837D0 (en) * | 1984-08-16 | 1984-09-19 | Beecham Group Plc | Compounds |
| GB8519154D0 (en) * | 1985-07-30 | 1985-09-04 | Ici Plc | Aromatic ethers |
| EP0244062A3 (de) * | 1986-03-03 | 1990-06-20 | Beecham Group Plc | Verwendung von Arylethanolamin-Derivaten zur Behandlung von Atherosclerose |
| IT1204416B (it) * | 1986-06-27 | 1989-03-01 | Midy Spa | Medicamenti a base di analoghi di feniletanolammine per il trattamento di disturbi gastro-intestinali ed uterini |
| CA1287061C (en) * | 1986-06-27 | 1991-07-30 | Roche Holding Ltd. | Pyridine ethanolamine derivatives |
| DE3623940A1 (de) * | 1986-07-16 | 1988-01-21 | Bayer Ag | Arylethanolhydroxylamine, verfahren zu ihrer herstellung und ihre verwendung zur leistungsfoerderung |
| GB8620951D0 (en) * | 1986-08-29 | 1986-10-08 | Beecham Group Plc | Compounds |
| DE3631009A1 (de) * | 1986-09-12 | 1988-03-24 | Bayer Ag | Arylethanolamine, verfahren zu ihrer herstellung und ihre verwendung zur leistungsfoerderung |
| EP0300290B1 (de) * | 1987-07-21 | 1991-12-18 | F. Hoffmann-La Roche Ag | Phenoxypropanolamine |
| FR2619379B1 (fr) * | 1987-08-12 | 1990-01-12 | Midy Spa | Procede pour la o-alkylation de n-(hydroxy) aralkyl-phenylethanolamines |
| EP0303546B1 (de) * | 1987-08-12 | 1994-12-28 | Sanofi | Verfahren zur O-Alkylierung von N-(Hydroxy)aralkylphenylethanolamin |
| GB8925032D0 (en) * | 1989-11-06 | 1989-12-28 | Ici Plc | Chemical compounds |
| JP2818958B2 (ja) * | 1990-02-23 | 1998-10-30 | 塩野義製薬株式会社 | ４―（４―アルコキシフェニル）―２―ブチルアミン誘導体およびその製造法 |
| US5106867A (en) * | 1990-05-04 | 1992-04-21 | American Cyanamid Company | Method of increasing lean meat in edible animals |
| US5245053A (en) * | 1990-05-04 | 1993-09-14 | American Cyanamid Company | Substituted 5-(2-(2-aryl-2-hydroxyethyl)-amino)propyl)-1,3-benzodioxoles |
| US5061727A (en) * | 1990-05-04 | 1991-10-29 | American Cyanamid Company | Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles |
| US5151439A (en) * | 1990-05-04 | 1992-09-29 | American Cyanamid Company | Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles |
| GB9111426D0 (en) * | 1991-05-28 | 1991-07-17 | Ici Plc | Chemical compounds |
| US5502078A (en) * | 1991-05-28 | 1996-03-26 | Zeneca Limited | Chemical compounds |
| US5858684A (en) * | 1991-08-23 | 1999-01-12 | The Brigham And Women's Hospital, Inc. | Method of screening calcium receptor-active molecules |
| US5763569A (en) * | 1991-08-23 | 1998-06-09 | The Brigham And Women's Hospital, Inc | Calcium receptor-active molecules |
| US6001884A (en) * | 1991-08-23 | 1999-12-14 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| US6031003A (en) * | 1991-08-23 | 2000-02-29 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| US5688938A (en) * | 1991-08-23 | 1997-11-18 | The Brigham & Women's Hospital, Inc. | Calcium receptor-active molecules |
| US6313146B1 (en) | 1991-08-23 | 2001-11-06 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| US6011068A (en) * | 1991-08-23 | 2000-01-04 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| GB9124512D0 (en) * | 1991-11-19 | 1992-01-08 | Smithkline Beecham Plc | Novel compounds |
| NO179246C (no) * | 1991-11-20 | 1996-09-04 | Sankyo Co | Aromatiske amino-alkoholderivater og mellomprodukter til fremstilling derav |
| US5962314A (en) * | 1993-02-23 | 1999-10-05 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
| GB9308178D0 (en) * | 1993-04-21 | 1993-06-02 | Smithkline Beecham Plc | Novel compounds |
| WO1994025427A1 (en) * | 1993-04-26 | 1994-11-10 | Fujisawa Pharmaceutical Co., Ltd. | Ethanolamine derivatives useful for the treatment of gastrointestinal disorders |
| WO1995004047A1 (en) * | 1993-07-31 | 1995-02-09 | Smithkline Beecham Plc | 2-benzoheterocyclyloxy or thiopropanolamine derivatives with adreno receptor agonist activity |
| US5563171A (en) * | 1993-11-05 | 1996-10-08 | American Cyanamid Company | Treatment of glaucoma and ocular hypertension with β3-adrenergic agonists |
| US5578638A (en) * | 1993-11-05 | 1996-11-26 | American Cyanamid Company | Treatment of glaucoma and ocular hypertension with β3 -adrenergic agonists |
| US5480908A (en) * | 1993-12-13 | 1996-01-02 | American Cyanamid Company | β3 -adrenergic agents benzodioxole dicarboxylates and their use in pharmaceutical compositions |
| US5776983A (en) * | 1993-12-21 | 1998-07-07 | Bristol-Myers Squibb Company | Catecholamine surrogates useful as β3 agonists |
| US5488064A (en) * | 1994-05-02 | 1996-01-30 | Bristol-Myers Squibb Company | Benzo 1,3 dioxole derivatives |
| US5491134A (en) * | 1994-09-16 | 1996-02-13 | Bristol-Myers Squibb Company | Sulfonic, phosphonic or phosphiniic acid β3 agonist derivatives |
| EP1275635A1 (de) | 1994-10-21 | 2003-01-15 | Nps Pharmaceuticals, Inc. | Kalzium-Rezeptor aktive Verbindungen |
| TW349091B (en) * | 1994-11-29 | 1999-01-01 | Dainippon Pharmaceutical Co | Indole derivatives |
| US5541204A (en) * | 1994-12-02 | 1996-07-30 | Bristol-Myers Squibb Company | Aryloxypropanolamine β 3 adrenergic agonists |
| EP0825189B1 (de) * | 1995-05-12 | 2002-01-02 | Nisshin Pharma Inc. | 1,4-benzodioxin-derivate |
| US6075040A (en) | 1996-09-05 | 2000-06-13 | Eli Lilly And Company | Selective β3 adrenergic agonists |
| ZA967892B (en) * | 1995-09-21 | 1998-03-18 | Lilly Co Eli | Selective β3 adrenergic agonists. |
| EP0882707B1 (de) | 1996-01-10 | 2003-10-08 | Asahi Kasei Kabushiki Kaisha | Neue trizyklische verbindungen und arzneimittelzusammensetzungen die diese enthalten |
| US5770615A (en) * | 1996-04-04 | 1998-06-23 | Bristol-Myers Squibb Company | Catecholamine surrogates useful as β3 agonists |
| ATE352537T1 (de) | 1996-05-01 | 2007-02-15 | Nps Pharma Inc | Verbindungen, die auf anorganische ionen- rezeptoren wirken |
| ATE215369T1 (de) | 1996-09-05 | 2002-04-15 | Lilly Co Eli | Carbazolanaloge als selektive beta3-adrenergische agonisten |
| WO1998013333A1 (fr) * | 1996-09-26 | 1998-04-02 | Kissei Pharmaceutical Co., Ltd. | Derives de 2-amino-1-(4-hydroxy-2-methylphenyl)propanol |
| EP0997458A4 (de) | 1997-07-03 | 2003-03-05 | Asahi Chemical Ind | Tricyclische verbindungen mit gesättigten ringen und diese enthaltende medizinische zubereitungen |
| ID24062A (id) * | 1997-07-25 | 2000-07-06 | Kissei Pharmaceutical | Turunan-turunan asam aminoetilfenoksiasetat dan obat untuk mengurangi nyeri dan membantu penyingkiran dalam litiasis saluran air kencing |
| CO5011072A1 (es) | 1997-12-05 | 2001-02-28 | Lilly Co Eli | Etanolaminas pirazinil substituidas como agfonistas de los receptores |
| EP1070046A1 (de) * | 1998-04-06 | 2001-01-24 | Fujisawa Pharmaceutical Co., Ltd. | Propanolaminderivate |
| WO1999052856A1 (fr) | 1998-04-14 | 1999-10-21 | Kissei Pharmaceutical Co., Ltd. | Derives de l'acide 2-methylpropionique et compositions medicinale correspondantes |
| MY126489A (en) * | 1998-07-08 | 2006-10-31 | Kissei Pharmaceutical | Phenoxyacetic acid derivatives and medicinal compositions containing the same |
| KR100502876B1 (ko) * | 2000-04-28 | 2005-07-21 | 아사히 가세이 파마 가부시키가이샤 | 신규 이환성 화합물 |
| JP2002053574A (ja) * | 2000-08-10 | 2002-02-19 | Nisshin Pharma Inc | １，４−ベンゾジオキサン環を有するプロパノールアミン誘導体 |
| ATE497948T1 (de) | 2001-10-25 | 2011-02-15 | Asahi Kasei Pharma Corp | Bicyclische verbindungen |
| UA79498C2 (en) * | 2002-09-05 | 2007-06-25 | Kissei Pharmaceutical | Intermediates for preparation of phenoxy-acetic derivates and processes of their preparation |
| WO2006043577A1 (ja) * | 2004-10-20 | 2006-04-27 | Mitsubishi Pharma Corporation | フェニルエタノールアミン化合物の製造方法及びその中間体 |
| CA2737349A1 (en) | 2008-10-09 | 2010-04-09 | Asahi Kasei Pharma Corporation | Indazole derivatives |
| US8008506B2 (en) | 2008-10-09 | 2011-08-30 | Asahi Kasei Pharma Corporation | Indazole compounds |
| CN102584609B (zh) * | 2011-01-06 | 2015-05-27 | 上海医药工业研究院 | 一种沙美特罗的制备方法 |
| ES2394349B1 (es) | 2012-08-29 | 2013-11-04 | Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii | Uso de agonistas selectivos de receptores beta-3 adrenérgicos para el tratamiento de hipertensión pulmonar |
| WO2014108449A1 (en) | 2013-01-08 | 2014-07-17 | Atrogi Ab | A screening method, a kit, a method of treatment and a compound for use in a method of treatment |
| GB201714740D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
| GB201714745D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
| GB201714734D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
| GB201714736D0 (en) | 2017-09-13 | 2017-10-25 | Atrogi Ab | New compounds and uses |
| GB202205895D0 (en) | 2022-04-22 | 2022-06-08 | Atrogi Ab | New medical uses |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4012444A (en) * | 1969-07-08 | 1977-03-15 | Allen & Hanburys Limited | 5-[1-Hydroxy-2-(1-methyl-3-phenylpropyl)aminoethyl] salicylamide and physiologically acceptable acid addition salts thereof |
| DE2034277A1 (en) * | 1970-07-10 | 1972-01-20 | Troponwerke Dinklage & Co, 5000 Köln Mulheim | 1-(3-hydroxyphenyl)-2-(1-(4-(2-hydroxy or ethoxy)-phenyl) - propyl-2-amino)-ethanol-(1)-with bronchodilatory action |
| JPS5310974B2 (de) * | 1974-06-10 | 1978-04-18 | ||
| US4146638A (en) * | 1976-02-17 | 1979-03-27 | Boehringer Ingelheim Gmbh | N-(3-phenoxy-2-hydroxy-propyl)-n-(2-phenyl-2-hydroxy-ethyl)-amines |
| JPS52113934A (en) * | 1976-03-19 | 1977-09-24 | Eisai Co Ltd | Phenethylamine derivatives and bronchodilator containing the same |
| JPS53149940A (en) * | 1977-06-02 | 1978-12-27 | Tanabe Seiyaku Co Ltd | Novel benzyl alcohol derivatives and their preparation |
-
1980
- 1980-06-09 AT AT80301927T patent/ATE1994T1/de active
- 1980-06-09 US US06/157,555 patent/US4338333A/en not_active Expired - Lifetime
- 1980-06-09 DE DE8080301927T patent/DE3061334D1/de not_active Expired
- 1980-06-09 EP EP80301927A patent/EP0023385B1/de not_active Expired
- 1980-06-10 NZ NZ193988A patent/NZ193988A/en unknown
- 1980-06-10 IL IL60288A patent/IL60288A0/xx unknown
- 1980-06-11 CA CA000353754A patent/CA1150297A/en not_active Expired
- 1980-06-13 IE IE1223/80A patent/IE49908B1/en not_active IP Right Cessation
- 1980-06-13 DK DK256580A patent/DK256580A/da unknown
- 1980-06-13 AU AU59307/80A patent/AU533432B2/en not_active Ceased
- 1980-06-16 ES ES492489A patent/ES492489A0/es active Granted
- 1980-06-16 ZA ZA00803576A patent/ZA803576B/xx unknown
- 1980-06-16 JP JP8126880A patent/JPS565444A/ja active Granted
-
1981
- 1981-02-19 ES ES499604A patent/ES499604A0/es active Granted
-
1985
- 1985-12-30 MY MY997/85A patent/MY8500997A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES8106274A1 (es) | 1981-08-01 |
| AU533432B2 (en) | 1983-11-24 |
| ES8202533A1 (es) | 1982-02-01 |
| IE801223L (en) | 1980-12-16 |
| ZA803576B (en) | 1981-06-24 |
| ES492489A0 (es) | 1981-08-01 |
| JPS6326744B2 (de) | 1988-05-31 |
| NZ193988A (en) | 1984-11-09 |
| DE3061334D1 (en) | 1983-01-20 |
| CA1150297A (en) | 1983-07-19 |
| JPS565444A (en) | 1981-01-20 |
| EP0023385B1 (de) | 1982-12-15 |
| ES499604A0 (es) | 1982-02-01 |
| MY8500997A (en) | 1985-12-31 |
| EP0023385A1 (de) | 1981-02-04 |
| DK256580A (da) | 1980-12-17 |
| US4338333A (en) | 1982-07-06 |
| IL60288A0 (en) | 1980-09-16 |
| AU5930780A (en) | 1981-01-08 |
| IE49908B1 (en) | 1986-01-08 |
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