PT876362E - Novos taxoides sua preparacao e composicoes farmaceuticas que os contem - Google Patents

Novos taxoides sua preparacao e composicoes farmaceuticas que os contem

Info

Publication number
PT876362E
PT876362E PT96942433T PT96942433T PT876362E PT 876362 E PT876362 E PT 876362E PT 96942433 T PT96942433 T PT 96942433T PT 96942433 T PT96942433 T PT 96942433T PT 876362 E PT876362 E PT 876362E
Authority
PT
Portugal
Prior art keywords
contain
preparation
pharmaceutical compositions
new taxoid
taxoid
Prior art date
Application number
PT96942433T
Other languages
English (en)
Portuguese (pt)
Inventor
Alain Commercon
Herve Bouchard
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of PT876362E publication Critical patent/PT876362E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT96942433T 1995-12-22 1996-12-19 Novos taxoides sua preparacao e composicoes farmaceuticas que os contem PT876362E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9515379A FR2742751B1 (fr) 1995-12-22 1995-12-22 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
PT876362E true PT876362E (pt) 2004-02-27

Family

ID=9485871

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96942433T PT876362E (pt) 1995-12-22 1996-12-19 Novos taxoides sua preparacao e composicoes farmaceuticas que os contem

Country Status (40)

Country Link
US (1) US5728849A (show.php)
EP (1) EP0876362B1 (show.php)
JP (1) JP3953106B2 (show.php)
KR (1) KR100500351B1 (show.php)
CN (1) CN1103766C (show.php)
AR (1) AR005197A1 (show.php)
AT (1) ATE250593T1 (show.php)
AU (1) AU712597B2 (show.php)
BG (1) BG63204B1 (show.php)
BR (1) BR9612135A (show.php)
CA (1) CA2238884C (show.php)
CO (1) CO4520184A1 (show.php)
CZ (1) CZ294972B6 (show.php)
DE (1) DE69630145T2 (show.php)
DK (1) DK0876362T3 (show.php)
DZ (1) DZ2149A1 (show.php)
EA (1) EA001533B1 (show.php)
ES (1) ES2202490T3 (show.php)
FR (1) FR2742751B1 (show.php)
HU (1) HU225032B1 (show.php)
IL (1) IL124994A (show.php)
IN (4) IN186768B (show.php)
MA (1) MA26412A1 (show.php)
MX (1) MX9804688A (show.php)
MY (1) MY113934A (show.php)
NO (1) NO317358B1 (show.php)
NZ (1) NZ324337A (show.php)
OA (1) OA10700A (show.php)
PE (1) PE25198A1 (show.php)
PL (1) PL189311B1 (show.php)
PT (1) PT876362E (show.php)
RO (1) RO116194B1 (show.php)
SK (1) SK282835B6 (show.php)
TN (1) TNSN96169A1 (show.php)
TR (1) TR199801179T2 (show.php)
TW (1) TW371659B (show.php)
UA (1) UA48205C2 (show.php)
UY (1) UY24386A1 (show.php)
WO (1) WO1997023473A1 (show.php)
ZA (1) ZA9610737B (show.php)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9920548D0 (en) * 1999-08-31 1999-11-03 Rhone Poulenc Rorer Sa Treatment of hepatocellular carcinoma
RU2264400C2 (ru) 2000-02-02 2005-11-20 Флорида Стейт Юниверсити Рисерч Фаундейшн, Инк. Таксан, фармацевтическая композиция на его основе и способ ингибирования роста опухоли
PT1757606E (pt) * 2001-02-24 2009-05-26 Boehringer Ingelheim Pharma Utilização de derivados de xantina como produto farmacêutico, bem como seu processo de preparação
US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
US20080107721A1 (en) * 2003-05-20 2008-05-08 Jonathan Lewis Combination Chemotherapy Comprising A Liposomal Platinum Complex
US7501426B2 (en) 2004-02-18 2009-03-10 Boehringer Ingelheim International Gmbh 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
DE102004054054A1 (de) 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
EP1669358A1 (en) * 2004-12-07 2006-06-14 Aventis Pharma S.A. Cytotoxic agents comprising new taxanes
DE102005035891A1 (de) 2005-07-30 2007-02-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
PE20080251A1 (es) 2006-05-04 2008-04-25 Boehringer Ingelheim Int Usos de inhibidores de dpp iv
EP1852108A1 (en) 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG DPP IV inhibitor formulations
NZ619413A (en) 2006-05-04 2015-08-28 Boehringer Ingelheim Int Polymorphs of a dpp-iv enzyme inhibitor
US20080207743A1 (en) * 2007-02-28 2008-08-28 Rodger Lamb Biologically Active Taxane Analogs and Methods of Treatment
US20110112069A1 (en) * 2007-08-17 2011-05-12 Boehringer Ingelheim International Gmbh Purin derivatives for use in the treatment of fab-related diseases
PE20140960A1 (es) 2008-04-03 2014-08-15 Boehringer Ingelheim Int Formulaciones que comprenden un inhibidor de dpp4
PE20100156A1 (es) * 2008-06-03 2010-02-23 Boehringer Ingelheim Int Tratamiento de nafld
KR20190016601A (ko) 2008-08-06 2019-02-18 베링거 인겔하임 인터내셔날 게엠베하 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
KR101791403B1 (ko) * 2008-08-15 2017-10-30 베링거 인겔하임 인터내셔날 게엠베하 Ｆａｂ-관련 질환의 치료에 사용하기 위한 퓨린 유도체
AU2009290911A1 (en) 2008-09-10 2010-03-18 Boehringer Ingelheim International Gmbh Combination therapy for the treatment of diabetes and related conditions
US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
JP2012512848A (ja) 2008-12-23 2012-06-07 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 有機化合物の塩の形態
TW201036975A (en) 2009-01-07 2010-10-16 Boehringer Ingelheim Int Treatment for diabetes in patients with inadequate glycemic control despite metformin therapy
MX364651B (es) 2009-11-27 2019-05-03 Boehringer Ingelheim Int Gmbh Star Inhibidores de dpp-iv, tales como la linagliptina, y composiciones farmacéuticas o combinaciones que comprenden los mismos, para usarse en el tratamiento de pacientes diabéticos tipificados genéticamente.
ES2935300T3 (es) 2010-05-05 2023-03-03 Boehringer Ingelheim Int Combiterapia
KR20190050871A (ko) 2010-06-24 2019-05-13 베링거 인겔하임 인터내셔날 게엠베하 당뇨병 요법
AR083878A1 (es) 2010-11-15 2013-03-27 Boehringer Ingelheim Int Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
DK3517539T3 (en) 2011-07-15 2023-01-16 Boehringer Ingelheim Int Farmaceutiske sammensætninger til behandling af type i og type ii diabetes
US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
ES2929025T3 (es) 2012-05-14 2022-11-24 Boehringer Ingelheim Int Linagliptina, un derivado de xantina como inhibidor de dpp-4, para su uso en el tratamiento del SRIS y/o de la septicemia
EP3685839A1 (en) 2012-05-14 2020-07-29 Boehringer Ingelheim International GmbH Linagliptin for use in the treatment of albuminuria and kidney related diseases
WO2013174767A1 (en) 2012-05-24 2013-11-28 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
AU2012395148B2 (en) 2012-11-24 2016-10-27 Hangzhou Dac Biotech Co., Ltd. Hydrophilic linkers and their uses for conjugation of drugs to cell binding molecules
FR3010839B1 (fr) * 2013-09-17 2017-04-21 Schneider Electric Ind Sas Dispositif de raccordement electrique d'au moins un conducteur dans une borne appartenant a un appareil electrique
CN106414465B (zh) 2014-02-28 2021-11-16 杭州多禧生物科技有限公司 带电荷链接体及其在共轭反应上的应用
JP6615109B2 (ja) 2014-02-28 2019-12-04 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｄｐｐ−４阻害薬の医学的使用
AU2015242213A1 (en) 2015-07-12 2018-03-08 Hangzhou Dac Biotech Co., Ltd Bridge linkers for conjugation of cell-binding molecules
US9839687B2 (en) 2015-07-15 2017-12-12 Suzhou M-Conj Biotech Co., Ltd. Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
CN109310697A (zh) 2016-06-10 2019-02-05 勃林格殷格翰国际有限公司 利格列汀和二甲双胍的组合
KR20220147720A (ko) 2016-11-14 2022-11-03 항저우 디에이씨 바이오테크 씨오, 엘티디 결합 링커, 그러한 결합 링커를 함유하는 세포 결합 분자-약물 결합체, 링커를 갖는 그러한 결합체의 제조 및 사용
EP4426727A2 (en) 2021-11-03 2024-09-11 Hangzhou Dac Biotech Co., Ltd. Specific conjugation of an antibody

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2017724C1 (ru) * 1990-07-12 1994-08-15 Дзе Юниверсити оф Канзас Способ получения производных таксола
US5059699A (en) * 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
FR2678930B1 (fr) * 1991-07-10 1995-01-13 Rhone Poulenc Rorer Sa Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii.
RU2059631C1 (ru) * 1991-11-29 1996-05-10 Дзе Юниверсити оф Канзас Производные таксола и фармацевтическая композиция, обладающая противоопухолевой активностью
DE69325454T2 (de) * 1992-04-17 2000-01-20 Abbott Laboratories, Abbott Park Taxol-derivate
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
MX9307777A (es) * 1992-12-15 1994-07-29 Upjohn Co 7-HALO-Y 7ß, 8ß-METANO-TAXOLES, USO ANTINEOPLASTICO Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN.

Also Published As

Publication number Publication date
DZ2149A1 (fr) 2002-10-23
SK85398A3 (en) 1998-11-04
TNSN96169A1 (fr) 2005-03-15
AR005197A1 (es) 1999-04-14
DE69630145D1 (de) 2003-10-30
KR100500351B1 (ko) 2005-12-21
CO4520184A1 (es) 1997-10-15
NO317358B1 (no) 2004-10-18
CA2238884C (fr) 2007-02-06
MA26412A1 (fr) 2004-12-20
EP0876362B1 (fr) 2003-09-24
RO116194B1 (ro) 2000-11-30
UY24386A1 (es) 2001-08-27
OA10700A (fr) 2002-11-27
ATE250593T1 (de) 2003-10-15
BR9612135A (pt) 1999-07-13
PE25198A1 (es) 1998-05-10
TW371659B (en) 1999-10-11
BG63204B1 (bg) 2001-06-29
CN1205697A (zh) 1999-01-20
EA199800588A1 (ru) 1998-12-24
MY113934A (en) 2002-06-29
EA001533B1 (ru) 2001-04-23
JP2000502671A (ja) 2000-03-07
JP3953106B2 (ja) 2007-08-08
CA2238884A1 (fr) 1997-07-03
AU1180997A (en) 1997-07-17
FR2742751A1 (fr) 1997-06-27
PL189311B1 (pl) 2005-07-29
EP0876362A1 (fr) 1998-11-11
NO982580L (no) 1998-06-05
NO982580D0 (no) 1998-06-05
PL327405A1 (en) 1998-12-07
CZ294972B6 (cs) 2005-04-13
BG102569A (en) 1999-04-30
KR19990076680A (ko) 1999-10-15
SK282835B6 (sk) 2002-12-03
HK1017895A1 (en) 1999-12-03
CZ196198A3 (cs) 1998-09-16
WO1997023473A1 (fr) 1997-07-03
US5728849A (en) 1998-03-17
IN188470B (show.php) 2002-09-28
NZ324337A (en) 2000-03-27
HUP9904046A3 (en) 2001-08-28
ES2202490T3 (es) 2004-04-01
CN1103766C (zh) 2003-03-26
AU712597B2 (en) 1999-11-11
IN186768B (show.php) 2001-11-03
DK0876362T3 (da) 2004-02-02
IN188469B (show.php) 2002-09-28
IL124994A0 (en) 1999-01-26
TR199801179T2 (xx) 1998-10-21
MX9804688A (es) 1998-10-31
IN188680B (show.php) 2002-10-26
DE69630145T2 (de) 2004-07-15
HUP9904046A1 (hu) 2001-04-28
FR2742751B1 (fr) 1998-01-30
ZA9610737B (en) 1997-06-27
HU225032B1 (en) 2006-05-29
IL124994A (en) 2000-12-06
UA48205C2 (uk) 2002-08-15

Similar Documents

Publication Publication Date Title
PT876362E (pt) Novos taxoides sua preparacao e composicoes farmaceuticas que os contem
PT835246E (pt) Compostos aromaticos e composicoes farmaceuticas que os contem
PT1112251E (pt) Derivados de azetidina sua preparacao e medicamentos que os contem
PT96438A (pt) Processo para preparacao de anti-oxidante lipideo-selectivos e de composicoes farmaceuticas que os contem
PT100779A (pt) Acidos amidazolil-alcenoico, composicoes farmaceuticas que os contem e seu uso
BR9710366A (pt) Derivados de taxane e drogas que os contêm
DE69618587D1 (de) Chinazoline und pharmazeutische zusammensetzungen
PT912613E (pt) Polissacaridos sinteticos processo para a sua preparacao e composicoes farmaceuticas que os contem
MX9203027A (es) Derivados heterociclicos de acilaminotiazoles y composicines farmaceuticas que los contienen.
PT952829E (pt) Composicao farmaceutica de fenofibrato que apresenta uma biodisponibilidade elevada e seu modo de preparacao
PT98369A (pt) Processo para a preparacao de azois substituidos e de composicoes farmaceuticas que os contem
PT99671A (pt) Processo para a preparacao de heparosanos-n,o-sulfatados e de composicoes farmaceuticas que os contem
PT879814E (pt) Compostos tri-aromaticos composicoes que os contem e utilizacoes
PT1112266E (pt) 4-amino-2-aril-pirimidinas substituidas, sua preparacao, sua utilizacao e composicoes farmaceuticas que as contem.
PT1038874E (pt) Derivados de oxima e produtos agro-quimicos que os contem
PT973763E (pt) Novos derivados do 2-(iminometil)amino-fenilo, sua preparacao, sua aplicacao na qualidade de medicamentos e composicoes farmaceuticas que os contem
PT703954E (pt) Composicoes de derivados de polifenois e sua preparacao
MX9204563A (es) Nuevos derivados de la (2-alquil-3-piridil)-metilpiperazina y composicion farmaceutica que los comprende.
FI944770A7 (fi) Neurotensiiniin vaikuttavia substituoituja 1-naftyylipyratsoli-3-karboksiamideja, niiden valmistus ja niitä sisältäviä farmaseuttisia koostumuksia
PT1187847E (pt) Derivados de estreptograminas sua preparacao e as composicoes que os contem
PT946567E (pt) Novos analogos da camptotecina, sua utilizacao como madicamentos e composicoes farmaceuticas que os contem
PT842927E (pt) 3-AMIDO-CROMANILSULFONIL(TIO)-UREIAS PROCESSOS PARA A SUA PREPARACAO SUA UTILIZACAO E COMPOSICOES FARMACêUTICAS QUE AS CONTEM
PT1049706E (pt) Novos penta-sacaridos os respectivos metodos de producao e as composicoes farmaceuticas que os contem
FI972988L (fi) Menetelmiä ja farmaseuttisia koostumuksia, joissa käytetään desmetyyliselegiliiniä
PT98816A (pt) Processo para a preparacao de tienodiazepinas e de composicoes farmaceuticas que as contem