PT87402B - Metodo para a preparacao de composicoes de pre-mistura alimentares de maduramicina - Google Patents
Metodo para a preparacao de composicoes de pre-mistura alimentares de maduramicina Download PDFInfo
- Publication number
- PT87402B PT87402B PT87402A PT8740288A PT87402B PT 87402 B PT87402 B PT 87402B PT 87402 A PT87402 A PT 87402A PT 8740288 A PT8740288 A PT 8740288A PT 87402 B PT87402 B PT 87402B
- Authority
- PT
- Portugal
- Prior art keywords
- ammonia
- laughs
- maduramycin
- vehicle
- preparation
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 25
- 238000000034 method Methods 0.000 title claims abstract description 11
- 238000002360 preparation method Methods 0.000 title claims abstract description 9
- 235000013305 food Nutrition 0.000 title claims description 12
- WQGJEAMPBSZCIF-HKSLRPGUSA-N Maduramicin Chemical group N.O1[C@@H](C)[C@H](OC)[C@@H](OC)C[C@H]1O[C@@H]1[C@H]([C@@]2(C)O[C@H](CC2)[C@@]2(C)O[C@]3(O[C@@H]([C@H](C)[C@@H](O)C3)[C@@H](C)[C@H]3[C@@H]([C@@H](OC)[C@H](C)[C@@](O)(CC(O)=O)O3)OC)CC2)O[C@@H]([C@@H]2[C@H](C[C@@H](C)[C@@](C)(O)O2)C)C1 WQGJEAMPBSZCIF-HKSLRPGUSA-N 0.000 title description 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims description 52
- 229910021529 ammonia Inorganic materials 0.000 claims description 25
- WQGJEAMPBSZCIF-WHSSCRKSSA-N azanium;2-[(2r,3s,4s,5r,6s)-6-[(1r)-1-[(2r,5r,7s,8r,9s)-2-[(2s,5r)-5-[(2r,3s,5r)-3-[(2r,4s,5s,6s)-4,5-dimethoxy-6-methyloxan-2-yl]oxy-5-[(2s,3s,5r,6s)-6-hydroxy-3,5,6-trimethyloxan-2-yl]oxolan-2-yl]-5-methyloxolan-2-yl]-7-hydroxy-2,8-dimethyl-1,10-dioxasp Chemical compound [NH4+].O1[C@@H](C)[C@H](OC)[C@@H](OC)C[C@H]1O[C@@H]1[C@H]([C@]2(C)O[C@@H](CC2)[C@]2(C)O[C@]3(O[C@@H]([C@H](C)[C@@H](O)C3)[C@@H](C)[C@H]3[C@@H]([C@@H](OC)[C@H](C)[C@@](O)(CC([O-])=O)O3)OC)CC2)O[C@@H]([C@@H]2[C@H](C[C@@H](C)[C@@](C)(O)O2)C)C1 WQGJEAMPBSZCIF-WHSSCRKSSA-N 0.000 claims description 15
- VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 claims description 9
- 150000003863 ammonium salts Chemical class 0.000 claims description 9
- 238000002156 mixing Methods 0.000 claims description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 6
- 239000000908 ammonium hydroxide Substances 0.000 claims description 4
- 239000002253 acid Substances 0.000 claims description 2
- 239000003795 chemical substances by application Substances 0.000 claims description 2
- 150000007513 acids Chemical class 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 230000003115 biocidal effect Effects 0.000 abstract description 4
- RWVUEZAROXKXRT-VQLSFVLHSA-N maduramicin Chemical compound O1[C@@H](C)[C@H](OC)[C@@H](OC)C[C@H]1O[C@@H]1[C@H]([C@@]2(C)O[C@H](CC2)[C@@]2(C)O[C@]3(O[C@@H]([C@H](C)[C@@H](O)C3)[C@@H](C)[C@H]3[C@@H]([C@@H](OC)[C@H](C)[C@@](O)(CC(O)=O)O3)OC)CC2)O[C@@H]([C@@H]2[C@H](C[C@@H](C)[C@@](C)(O)O2)C)C1 RWVUEZAROXKXRT-VQLSFVLHSA-N 0.000 abstract 1
- 229950006915 maduramicin Drugs 0.000 abstract 1
- 239000000243 solution Substances 0.000 description 13
- WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 description 6
- 150000003839 salts Chemical class 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- 239000003814 drug Substances 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 239000008367 deionised water Substances 0.000 description 3
- 229910021641 deionized water Inorganic materials 0.000 description 3
- 230000014759 maintenance of location Effects 0.000 description 3
- 239000000758 substrate Substances 0.000 description 3
- 240000008042 Zea mays Species 0.000 description 2
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 2
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 2
- 235000019445 benzyl alcohol Nutrition 0.000 description 2
- 239000000969 carrier Substances 0.000 description 2
- 235000005822 corn Nutrition 0.000 description 2
- 238000010790 dilution Methods 0.000 description 2
- 239000012895 dilution Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 1
- 235000007466 Corylus avellana Nutrition 0.000 description 1
- 235000019764 Soybean Meal Nutrition 0.000 description 1
- 238000005273 aeration Methods 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 238000009835 boiling Methods 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 235000013312 flour Nutrition 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000000069 prophylactic effect Effects 0.000 description 1
- 239000002002 slurry Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000004455 soybean meal Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/195—Antibiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Polymers & Plastics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Food Science & Technology (AREA)
- Zoology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Husbandry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Fodder In General (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/049,053 US4816480A (en) | 1987-05-12 | 1987-05-12 | Method for the preparation of feed premix in compositions of maduramicin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PT87402A PT87402A (pt) | 1989-05-31 |
| PT87402B true PT87402B (pt) | 1992-09-30 |
Family
ID=21957822
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT87402A PT87402B (pt) | 1987-05-12 | 1988-05-04 | Metodo para a preparacao de composicoes de pre-mistura alimentares de maduramicina |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4816480A (en, 2012) |
| EP (1) | EP0290792B1 (en, 2012) |
| JP (1) | JP2581752B2 (en, 2012) |
| KR (1) | KR960014992B1 (en, 2012) |
| AR (1) | AR240019A1 (en, 2012) |
| AT (1) | ATE79223T1 (en, 2012) |
| AU (1) | AU597821B2 (en, 2012) |
| CA (1) | CA1332797C (en, 2012) |
| DE (1) | DE3873601T2 (en, 2012) |
| DK (1) | DK172835B1 (en, 2012) |
| ES (1) | ES2033982T3 (en, 2012) |
| GR (1) | GR3005815T3 (en, 2012) |
| IE (1) | IE62881B1 (en, 2012) |
| IL (1) | IL86103A (en, 2012) |
| NZ (1) | NZ224507A (en, 2012) |
| PT (1) | PT87402B (en, 2012) |
| ZA (1) | ZA883364B (en, 2012) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX9308001A (es) * | 1992-12-21 | 1994-08-31 | Lilly Co Eli | Premezcla para piensos de animales que contiene tilosina y procedimiento para su obtencion. |
| RU2413424C2 (ru) * | 2007-04-04 | 2011-03-10 | АЛФАРМА, Инк. | Композиции мадурамицина, способы получения и применения |
| CN101879142B (zh) * | 2010-06-11 | 2011-09-07 | 濮阳泓天威药业有限公司 | 马度米星铵预混剂的制备方法 |
| CN106474073A (zh) * | 2016-12-22 | 2017-03-08 | 甘肃汇能生物工程有限公司 | 一种1%马杜米星铵颗粒的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4278663A (en) * | 1980-01-30 | 1981-07-14 | Hoffmann-La Roche Inc. | Antibiotic X-14868A, B, C and D |
| US4407946A (en) * | 1981-10-22 | 1983-10-04 | American Cyanamid Company | Process for producing antibiotic X-14868A |
| US4824829A (en) * | 1984-08-15 | 1989-04-25 | American Cyanamid Company | Non-dusting antibiotic, anticoccidial premix compositions and a process for their manufacture |
| EP0182117B1 (en) * | 1984-11-15 | 1989-10-18 | American Cyanamid Company | Anticoccidial compostions |
-
1987
- 1987-05-12 US US07/049,053 patent/US4816480A/en not_active Expired - Lifetime
-
1988
- 1988-04-11 ES ES198888105697T patent/ES2033982T3/es not_active Expired - Lifetime
- 1988-04-11 DE DE8888105697T patent/DE3873601T2/de not_active Expired - Lifetime
- 1988-04-11 EP EP88105697A patent/EP0290792B1/en not_active Expired - Lifetime
- 1988-04-11 AT AT88105697T patent/ATE79223T1/de not_active IP Right Cessation
- 1988-04-18 IL IL86103A patent/IL86103A/xx not_active IP Right Cessation
- 1988-05-04 PT PT87402A patent/PT87402B/pt not_active IP Right Cessation
- 1988-05-05 NZ NZ224507A patent/NZ224507A/xx unknown
- 1988-05-09 JP JP63110663A patent/JP2581752B2/ja not_active Expired - Lifetime
- 1988-05-10 CA CA000566370A patent/CA1332797C/en not_active Expired - Lifetime
- 1988-05-11 KR KR1019880005483A patent/KR960014992B1/ko not_active Expired - Fee Related
- 1988-05-11 AR AR310827A patent/AR240019A1/es active
- 1988-05-11 AU AU16051/88A patent/AU597821B2/en not_active Ceased
- 1988-05-11 ZA ZA883364A patent/ZA883364B/xx unknown
- 1988-05-11 DK DK198802594A patent/DK172835B1/da not_active IP Right Cessation
- 1988-05-11 IE IE142388A patent/IE62881B1/en not_active IP Right Cessation
-
1992
- 1992-09-29 GR GR920400648T patent/GR3005815T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2033982T3 (es) | 1993-04-01 |
| DK172835B1 (da) | 1999-08-09 |
| KR960014992B1 (ko) | 1996-10-23 |
| IE62881B1 (en) | 1995-03-08 |
| JP2581752B2 (ja) | 1997-02-12 |
| KR880013564A (ko) | 1988-12-21 |
| AU1605188A (en) | 1988-11-17 |
| GR3005815T3 (en, 2012) | 1993-06-07 |
| DE3873601D1 (de) | 1992-09-17 |
| PT87402A (pt) | 1989-05-31 |
| US4816480A (en) | 1989-03-28 |
| DK259488A (da) | 1988-11-13 |
| DK259488D0 (da) | 1988-05-11 |
| EP0290792A2 (en) | 1988-11-17 |
| AU597821B2 (en) | 1990-06-07 |
| ZA883364B (en) | 1988-11-14 |
| DE3873601T2 (de) | 1993-03-11 |
| EP0290792A3 (en) | 1990-08-08 |
| CA1332797C (en) | 1994-11-01 |
| IE881423L (en) | 1988-11-12 |
| JPS63287448A (ja) | 1988-11-24 |
| ATE79223T1 (de) | 1992-08-15 |
| IL86103A (en) | 1991-09-16 |
| IL86103A0 (en) | 1988-11-15 |
| AR240019A1 (es) | 1990-01-31 |
| NZ224507A (en) | 1990-03-27 |
| EP0290792B1 (en) | 1992-08-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG3A | Patent granted, date of granting |
Effective date: 19920304 |
|
| PC3A | Transfer or assignment |
Free format text: 960626 F. HOFFMANN-LA ROCHE AG. CH |
|
| MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20020930 |