PT731812E - Metodo para isolar poli-beta-1-4-n-acetilglucosamina - Google Patents
Metodo para isolar poli-beta-1-4-n-acetilglucosaminaInfo
- Publication number
- PT731812E PT731812E PT95904174T PT95904174T PT731812E PT 731812 E PT731812 E PT 731812E PT 95904174 T PT95904174 T PT 95904174T PT 95904174 T PT95904174 T PT 95904174T PT 731812 E PT731812 E PT 731812E
- Authority
- PT
- Portugal
- Prior art keywords
- glcnac
- beta
- relates
- present
- reformulations
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/12—Unicellular algae; Culture media therefor
- C12N1/125—Unicellular algae isolates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/042—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
- C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
- C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/89—Algae ; Processes using algae
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- General Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Immunology (AREA)
- Botany (AREA)
- Vascular Medicine (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Biomedical Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Urology & Nephrology (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/160,569 US5622834A (en) | 1993-12-01 | 1993-12-01 | Method of isolating poly-β-1-4-N-acetylglucosamine from microalgal culture |
Publications (1)
Publication Number | Publication Date |
---|---|
PT731812E true PT731812E (pt) | 2004-08-31 |
Family
ID=22577431
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT95904174T PT731812E (pt) | 1993-12-01 | 1994-12-01 | Metodo para isolar poli-beta-1-4-n-acetilglucosamina |
Country Status (15)
Country | Link |
---|---|
US (2) | US5622834A (pt) |
EP (2) | EP1452546A3 (pt) |
JP (3) | JP3993633B2 (pt) |
CN (1) | CN1142833B (pt) |
AT (1) | ATE263785T1 (pt) |
AU (1) | AU695850B2 (pt) |
CA (1) | CA2177823C (pt) |
DE (1) | DE69433692T2 (pt) |
DK (1) | DK0731812T3 (pt) |
ES (1) | ES2219659T3 (pt) |
IL (1) | IL111825A0 (pt) |
NZ (1) | NZ277662A (pt) |
PT (1) | PT731812E (pt) |
TW (1) | TW458987B (pt) |
WO (1) | WO1995015343A1 (pt) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6743783B1 (en) * | 1993-12-01 | 2004-06-01 | Marine Polymer Technologies, Inc. | Pharmaceutical compositions comprising poly-β-1→4-N-acetylglucosamine |
US6063911A (en) * | 1993-12-01 | 2000-05-16 | Marine Polymer Technologies, Inc. | Methods and compositions for treatment of cell proliferative disorders |
US5858350A (en) | 1993-12-01 | 1999-01-12 | Marine Polymer Technologies | Methods and compositions for poly-β-1→4-N-acetylglucosamine cell therapy system |
US5931165A (en) * | 1994-09-06 | 1999-08-03 | Fusion Medical Technologies, Inc. | Films having improved characteristics and methods for their preparation and use |
US5791352A (en) * | 1996-06-19 | 1998-08-11 | Fusion Medical Technologies, Inc. | Methods and compositions for inhibiting tissue adhesion |
JP3690771B2 (ja) * | 1997-10-13 | 2005-08-31 | 株式会社ノエビア | 皮膚外用剤 |
CN1098354C (zh) * | 1998-11-12 | 2003-01-08 | 武汉大学 | 双酶催化法合成1-β-D-呋喃核糖苷-1,2,4-三氮唑-3-甲酰胺 |
FR2791262B1 (fr) * | 1999-03-22 | 2001-09-28 | Virbac Sa | Compositions a base de chondroitine et de chitosan pour la protection, le traitement ou le remplacement des tissus conjonctifs |
JP2001031592A (ja) * | 1999-07-16 | 2001-02-06 | Fujibio Co Ltd | キチン・キトサンによるハロゲン含有医薬の副作用防止方法及びそのための配合剤 |
US7041657B2 (en) * | 2001-02-12 | 2006-05-09 | Marine Polymer Technologies Inc. | Compositions and methods for modulation of vascular structure and/or function |
TW583190B (en) * | 2001-04-04 | 2004-04-11 | Dainichiseika Color Chem | Purified chitins and production process thereof |
PL196686B1 (pl) * | 2002-02-07 | 2008-01-31 | Abbott Lab De Costa Rica Ltd | Sposób oczyszczania chitozanu z białek |
AU2003303522B2 (en) * | 2002-12-31 | 2009-05-28 | Marine Polymer Technologies, Inc. | Hemostatic compositions and uses therefor |
NZ542501A (en) | 2003-02-24 | 2009-09-25 | Marinepolymer Tech Inc | Compositions comprising chitin or chitosan and use thereof |
CN1232257C (zh) * | 2003-03-27 | 2005-12-21 | 中国人民解放军第三军医大学 | N-乙酰氨基葡萄糖在制备治疗和控制物理化学因素致非特异性炎症的药物中的应用 |
EP1635782A1 (de) * | 2003-05-24 | 2006-03-22 | JUVENA (International) AG | Gewebekulturmedien als bestandteil von kosmetika |
AU2004273867B2 (en) | 2003-09-12 | 2011-01-27 | Marine Polymer Technologies, Inc. | Vascular access preservation in hemodialysis patients |
WO2006057308A1 (ja) * | 2004-11-25 | 2006-06-01 | Dainichiseika Color & Chemicals Mfg. Co., Ltd. | キトサン中のトロポミオシン測定方法 |
US20070086958A1 (en) * | 2005-10-14 | 2007-04-19 | Medafor, Incorporated | Formation of medically useful gels comprising microporous particles and methods of use |
US20070087061A1 (en) * | 2005-10-14 | 2007-04-19 | Medafor, Incorporated | Method and composition for creating and/or activating a platelet-rich gel by contact with a porous particulate material, for use in wound care, tissue adhesion, or as a matrix for delivery of therapeutic components |
JPWO2007046517A1 (ja) * | 2005-10-17 | 2009-04-23 | ヤマハ発動機株式会社 | βキチンの製造方法 |
WO2008103345A2 (en) | 2007-02-19 | 2008-08-28 | Marine Polymer Technologies, Inc. | Hemostatic compositions and therapeutic regimens |
US8932560B2 (en) | 2007-09-04 | 2015-01-13 | University of Maryland, College Parke | Advanced functional biocompatible polymeric matrix used as a hemostatic agent and system for damaged tissues and cells |
NZ599338A (en) | 2007-06-27 | 2013-11-29 | Marinepolymer Tech Inc | Complexes of il-15 and il-15ralpha and uses thereof |
US8486033B2 (en) * | 2007-07-18 | 2013-07-16 | Marine Polymer Technologies, Inc. | Application of polymeric materials to screens to facilitate hemostasis and wound healing |
AU2008275935A1 (en) * | 2007-07-18 | 2009-01-22 | Marine Polymer Technologies, Inc. | Application of polymeric materials to screens to facilitate hemostasis and wound healing |
WO2009132228A1 (en) * | 2008-04-24 | 2009-10-29 | Medtronic, Inc. | Chitosan-containing protective composition |
CA2722145A1 (en) | 2008-04-24 | 2009-10-29 | Medtronic, Inc. | Rehydratable thiolated polysaccharide particles and sponge |
CN106046396B (zh) * | 2008-04-24 | 2019-02-22 | 麦德托尼克公司 | 可再水化的多糖颗粒和海绵体 |
JP5833919B2 (ja) * | 2008-04-24 | 2015-12-16 | メドトロニック,インコーポレイテッド | キトサンと酸化多糖とに基づく保護用ゲル |
EP2313104B2 (en) * | 2008-04-24 | 2020-08-26 | Medtronic, Inc | Thiolated chitosan gel |
EP2498820B1 (en) | 2009-11-13 | 2019-01-09 | University of Maryland, College Park | Advanced functional biocompatible foam used as a hemostatic agent for compressible and non-compressible acute wounds |
CN103108638B (zh) | 2010-04-15 | 2016-11-09 | 海洋聚合物技术公司 | 聚-n-乙酰葡萄糖胺纳米纤维的抗菌应用 |
WO2012142581A1 (en) | 2011-04-15 | 2012-10-18 | Marine Polymer Technologies, Inc. | Treatment of disease with poly-n-acety glucosamine nanofibers |
CN106045588A (zh) | 2011-09-14 | 2016-10-26 | 诺维信生物农业公司 | 组合使用脂壳寡糖和/或壳寡糖与解磷微生物促植物生长 |
CN107258790A (zh) | 2011-09-23 | 2017-10-20 | 诺维信生物农业公司 | 用于增强植物生长的壳寡糖和方法 |
BR112014029752A2 (pt) * | 2012-05-30 | 2017-06-27 | Clariant Finance Bvi Ltd | uso de n-metil-n-acilglucaminas como estabilizadores de frio em soluções de tensoativos |
US9616088B2 (en) | 2013-03-13 | 2017-04-11 | Gel-E, Inc. | Advanced functional biocompatible polymer putty used as a hemostatic agent for treating damaged tissue and cells |
MX2015011418A (es) | 2013-03-14 | 2015-12-16 | Marinepolymer Tech Inc | Tratamiento de enfermedades con nanofibras de poli-n-acetilglucosamina. |
CN104056298B (zh) * | 2013-03-18 | 2017-04-26 | 李锋 | 无规共聚物的伤口应用 |
US9192574B2 (en) | 2013-10-24 | 2015-11-24 | Medtronic Xomed, Inc. | Chitosan paste wound dressing |
US9192692B2 (en) | 2013-10-24 | 2015-11-24 | Medtronic Xomed, Inc. | Chitosan stenting paste |
EP3034612A1 (en) | 2014-12-16 | 2016-06-22 | Greenaltech, S.L. | Chitin and chitosan producing methods |
CN114269350B (zh) * | 2019-08-14 | 2024-07-23 | 林春木 | 局部止血组合物 |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1038367A (en) * | 1963-05-28 | 1966-08-10 | Beecham Group Ltd | Penicillin derivatives |
US3988411A (en) * | 1974-02-11 | 1976-10-26 | American Cyanamid Company | Spinning and shaping poly-(N-acetyl-D-glucosamine) |
US3989535A (en) * | 1974-02-11 | 1976-11-02 | American Cyanamid Company | Solution of poly(N-acetyl-D-glucosamine) |
JPS55152705A (en) * | 1979-05-18 | 1980-11-28 | Mitsubishi Rayon Co Ltd | Preparation of water-soluble alkali chitin |
US4378017A (en) * | 1980-03-21 | 1983-03-29 | Kureha Kagaku Kogyo Kabushiki Kaisha | Composite material of de-N-acetylated chitin and fibrous collagen |
US4532134A (en) * | 1981-04-06 | 1985-07-30 | Malette William Graham | Method of achieving hemostasis, inhibiting fibroplasia, and promoting tissue regeneration in a tissue wound |
US4605623A (en) * | 1982-11-08 | 1986-08-12 | Malette William Graham | Method of altering growth and development and suppressing contamination microorganisms in cell or tissue culture |
EP0171254B1 (en) * | 1984-08-03 | 1991-06-19 | Unitika Ltd. | Shaped chitin body |
JPH0611810B2 (ja) * | 1984-08-23 | 1994-02-16 | ユニチカ株式会社 | 多孔性キチン成形体及びその製造方法 |
US4895724A (en) * | 1985-06-07 | 1990-01-23 | Pfizer Inc. | Chitosan compositions for controlled and prolonged release of macromolecules |
JPS62288602A (ja) * | 1986-06-06 | 1987-12-15 | Agency Of Ind Science & Technol | キトサン変性物粒子の製造方法 |
US5008116A (en) * | 1988-11-14 | 1991-04-16 | Frederick Cahn | Immunostimulatory microsphere |
US5071977A (en) * | 1989-05-10 | 1991-12-10 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Plaque inhibiting oligosaccharide |
US5093319A (en) * | 1989-10-31 | 1992-03-03 | Pfizer Hospital Products Group, Inc. | Use of derivatives of chitin soluble in aqueous solutions for preventing adhesions |
JPH0691819B2 (ja) * | 1991-05-27 | 1994-11-16 | 工業技術院長 | デアセチラーゼの製造方法 |
US5229123A (en) * | 1991-10-09 | 1993-07-20 | Hoffmann-La Roche Inc. | Antifungal agents |
US5219749A (en) * | 1991-10-09 | 1993-06-15 | Institute For Molecular Biology & Biotechnology/Forth | Process for isolating and preparing purified chitin deacetylase |
IL100096A (en) * | 1991-11-20 | 1996-03-31 | Univ Ramot | Method for entrapment of active materials in chitosan |
AU3065192A (en) * | 1991-12-20 | 1993-07-28 | Howmedica Inc. | Ultra-pure polysaccharide materials for medical use |
US5260002A (en) * | 1991-12-23 | 1993-11-09 | Vanderbilt University | Method and apparatus for producing uniform polymeric spheres |
-
1993
- 1993-12-01 US US08/160,569 patent/US5622834A/en not_active Expired - Lifetime
-
1994
- 1994-11-30 IL IL11182594A patent/IL111825A0/xx not_active IP Right Cessation
- 1994-12-01 AU AU12969/95A patent/AU695850B2/en not_active Ceased
- 1994-12-01 WO PCT/US1994/013706 patent/WO1995015343A1/en active IP Right Grant
- 1994-12-01 DE DE69433692T patent/DE69433692T2/de not_active Expired - Lifetime
- 1994-12-01 EP EP04007828A patent/EP1452546A3/en not_active Withdrawn
- 1994-12-01 NZ NZ277662A patent/NZ277662A/en not_active IP Right Cessation
- 1994-12-01 JP JP51572195A patent/JP3993633B2/ja not_active Expired - Lifetime
- 1994-12-01 AT AT95904174T patent/ATE263785T1/de active
- 1994-12-01 PT PT95904174T patent/PT731812E/pt unknown
- 1994-12-01 CA CA002177823A patent/CA2177823C/en not_active Expired - Fee Related
- 1994-12-01 DK DK95904174T patent/DK0731812T3/da active
- 1994-12-01 ES ES95904174T patent/ES2219659T3/es not_active Expired - Lifetime
- 1994-12-01 US US08/347,911 patent/US5623064A/en not_active Expired - Lifetime
- 1994-12-01 EP EP95904174A patent/EP0731812B1/en not_active Expired - Lifetime
- 1994-12-01 CN CN941949125A patent/CN1142833B/zh not_active Expired - Fee Related
-
1995
- 1995-02-28 TW TW083111374A patent/TW458987B/zh not_active IP Right Cessation
-
2004
- 2004-03-03 JP JP2004059902A patent/JP2004211101A/ja not_active Withdrawn
-
2008
- 2008-10-16 JP JP2008267438A patent/JP2009079223A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
CA2177823A1 (en) | 1995-06-08 |
TW458987B (en) | 2001-10-11 |
JP2009079223A (ja) | 2009-04-16 |
AU695850B2 (en) | 1998-08-27 |
EP1452546A3 (en) | 2004-10-13 |
NZ277662A (en) | 1998-04-27 |
ATE263785T1 (de) | 2004-04-15 |
JPH09506126A (ja) | 1997-06-17 |
DE69433692T2 (de) | 2005-03-10 |
US5622834A (en) | 1997-04-22 |
CA2177823C (en) | 2002-04-30 |
EP0731812A1 (en) | 1996-09-18 |
ES2219659T3 (es) | 2004-12-01 |
DE69433692D1 (de) | 2004-05-13 |
EP0731812A4 (en) | 1997-06-18 |
AU1296995A (en) | 1995-06-19 |
WO1995015343A1 (en) | 1995-06-08 |
EP1452546A2 (en) | 2004-09-01 |
CN1142833B (zh) | 2010-06-02 |
EP0731812B1 (en) | 2004-04-07 |
DK0731812T3 (da) | 2004-08-02 |
IL111825A0 (en) | 1995-01-24 |
JP3993633B2 (ja) | 2007-10-17 |
CN1142833A (zh) | 1997-02-12 |
JP2004211101A (ja) | 2004-07-29 |
US5623064A (en) | 1997-04-22 |
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