PT72834A - Method of synthesis within a bacterial host a selected mature protein or polypeptide - Google Patents

Method of synthesis within a bacterial host a selected mature protein or polypeptide

Info

Publication number
PT72834A
PT72834A PT72834A PT7283481A PT72834A PT 72834 A PT72834 A PT 72834A PT 72834 A PT72834 A PT 72834A PT 7283481 A PT7283481 A PT 7283481A PT 72834 A PT72834 A PT 72834A
Authority
PT
Portugal
Prior art keywords
host
polypeptide
cloning vehicle
mature protein
synthesis
Prior art date
Application number
PT72834A
Other languages
English (en)
Other versions
PT72834B (en
Inventor
Walter Gilbert
Karen Talmadge
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22485649&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT72834(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Harvard College filed Critical Harvard College
Publication of PT72834A publication Critical patent/PT72834A/pt
Publication of PT72834B publication Critical patent/PT72834B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT72834A 1980-04-11 1981-04-09 Method of synthesis within a bacterial host a selected mature protein or polypeptide PT72834B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/139,225 US4338397A (en) 1980-04-11 1980-04-11 Mature protein synthesis

Publications (2)

Publication Number Publication Date
PT72834A true PT72834A (pt) 1981-05-01
PT72834B PT72834B (en) 1982-06-18

Family

ID=22485649

Family Applications (1)

Application Number Title Priority Date Filing Date
PT72834A PT72834B (en) 1980-04-11 1981-04-09 Method of synthesis within a bacterial host a selected mature protein or polypeptide

Country Status (19)

Country Link
US (1) US4338397A (pt)
EP (1) EP0038182B2 (pt)
JP (1) JPH0773504B2 (pt)
KR (1) KR830005355A (pt)
AT (1) ATE30336T1 (pt)
AU (1) AU531566B2 (pt)
BR (1) BR8102164A (pt)
CA (1) CA1175369A (pt)
DD (1) DD158797A5 (pt)
DE (1) DE3176493D1 (pt)
DK (1) DK161681A (pt)
ES (1) ES8202589A1 (pt)
FI (1) FI811100L (pt)
GR (1) GR74459B (pt)
IL (1) IL62614A (pt)
NZ (1) NZ196768A (pt)
PH (1) PH18603A (pt)
PT (1) PT72834B (pt)
ZA (1) ZA812382B (pt)

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ATE30336T1 (de) 1987-11-15
KR830005355A (ko) 1983-08-13
CA1175369A (en) 1984-10-02
DK161681A (da) 1981-10-12
PT72834B (en) 1982-06-18
EP0038182B1 (en) 1987-10-21
BR8102164A (pt) 1981-10-13
PH18603A (en) 1985-08-21
US4338397A (en) 1982-07-06
ES501196A0 (es) 1982-02-01
ES8202589A1 (es) 1982-02-01
IL62614A0 (en) 1981-06-29
EP0038182A3 (en) 1982-05-26
AU6935481A (en) 1981-10-15
IL62614A (en) 1985-01-31
JPH0773504B2 (ja) 1995-08-09
JPS56154999A (en) 1981-11-30
AU531566B2 (en) 1983-08-25
FI811100L (fi) 1981-10-12
EP0038182A2 (en) 1981-10-21
DE3176493D1 (en) 1987-11-26
ZA812382B (en) 1982-04-28
NZ196768A (en) 1985-03-20
DD158797A5 (de) 1983-02-02
EP0038182B2 (en) 1993-12-15
GR74459B (pt) 1984-06-28

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