PT721343E - Formulacoes farmaceuticas de factor de crescimento do tecido nervoso - Google Patents
Formulacoes farmaceuticas de factor de crescimento do tecido nervosoInfo
- Publication number
- PT721343E PT721343E PT94925903T PT94925903T PT721343E PT 721343 E PT721343 E PT 721343E PT 94925903 T PT94925903 T PT 94925903T PT 94925903 T PT94925903 T PT 94925903T PT 721343 E PT721343 E PT 721343E
- Authority
- PT
- Portugal
- Prior art keywords
- growth factor
- pharmaceutical formulations
- tissue growth
- nervous tissue
- nerve growth
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/839—Nerves; brain
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Psychology (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/109,798 US6277828B1 (en) | 1993-08-20 | 1993-08-20 | Pharmaceutical formulations of nerve growth factor |
Publications (1)
Publication Number | Publication Date |
---|---|
PT721343E true PT721343E (pt) | 2003-01-31 |
Family
ID=22329623
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT94925903T PT721343E (pt) | 1993-08-20 | 1994-08-16 | Formulacoes farmaceuticas de factor de crescimento do tecido nervoso |
Country Status (32)
Country | Link |
---|---|
US (2) | US6277828B1 (pt) |
EP (1) | EP0721343B1 (pt) |
JP (2) | JP4592830B2 (pt) |
KR (1) | KR100341193B1 (pt) |
CN (1) | CN1163265C (pt) |
AT (1) | ATE226085T1 (pt) |
AU (1) | AU677699B2 (pt) |
BG (1) | BG62951B1 (pt) |
BR (1) | BR9407278A (pt) |
CA (1) | CA2169834C (pt) |
CZ (1) | CZ292422B6 (pt) |
DE (1) | DE69431562T2 (pt) |
DK (1) | DK0721343T3 (pt) |
ES (1) | ES2181723T3 (pt) |
FI (1) | FI113241B (pt) |
HK (1) | HK1012990A1 (pt) |
HU (1) | HU228152B1 (pt) |
IL (3) | IL110725A (pt) |
LT (1) | LT4051B (pt) |
LV (1) | LV11279B (pt) |
NO (1) | NO317627B1 (pt) |
NZ (1) | NZ271873A (pt) |
PL (1) | PL176387B1 (pt) |
PT (1) | PT721343E (pt) |
RO (1) | RO114742B1 (pt) |
RU (1) | RU2126265C1 (pt) |
SI (1) | SI9420048B (pt) |
SK (1) | SK284064B6 (pt) |
TW (1) | TW427905B (pt) |
UA (1) | UA43348C2 (pt) |
WO (1) | WO1995005845A1 (pt) |
ZA (1) | ZA946333B (pt) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5981485A (en) | 1997-07-14 | 1999-11-09 | Genentech, Inc. | Human growth hormone aqueous formulation |
US6444201B1 (en) * | 1995-05-12 | 2002-09-03 | The Rockefeller University | Treatment of alzheimer disease by modulation of synapsins |
WO1997017087A1 (en) * | 1995-11-07 | 1997-05-15 | Genentech, Inc. | Stabilizing formulation for ngf |
US6090781A (en) * | 1996-11-06 | 2000-07-18 | Genentech, Inc. | Stabilizing formulation for NGF |
US6964947B1 (en) * | 1995-11-07 | 2005-11-15 | Genentech, Inc. | Stabilizing formulation for NGF |
JP2000511059A (ja) * | 1996-05-29 | 2000-08-29 | ユニバーサル プリザーベーション テクノロジーズ,インコーポレイテッド | ガラス化による長期貯蔵保存 |
CN1059597C (zh) * | 1996-08-08 | 2000-12-20 | 陈素兰 | 神经损伤修复制剂 |
WO1998048832A1 (en) * | 1997-05-01 | 1998-11-05 | Protechtion Unlimited, Inc. | Nerve growth factor as a vaccine adjuvant |
US6313089B1 (en) | 1997-08-20 | 2001-11-06 | Duke University | Complexes of apolipoprotein E and ciliary neurotrophic factor (CNTF) and methods of use |
EP1019081A2 (en) * | 1997-09-30 | 2000-07-19 | Duke University | Apolipoprotein e/growth factor complexes and methods of use |
US6979442B1 (en) | 1998-08-17 | 2005-12-27 | Pfizer Inc. | Stabilized protein compositions |
KR20040065278A (ko) * | 2001-12-21 | 2004-07-21 | 노보 노르디스크 에이/에스 | 변경된 인자 ⅶ 폴리펩티드의 액체 조성물 |
ATE428439T1 (de) * | 2001-12-21 | 2009-05-15 | Novo Nordisk Healthcare Ag | Flüssige zusammensetzung aus faktor vii polypeptiden |
US20040009918A1 (en) * | 2002-05-03 | 2004-01-15 | Hanne Nedergaard | Stabilised solid compositions of modified factor VII |
EP2283856B1 (en) | 2002-06-21 | 2017-09-20 | Novo Nordisk Health Care AG | Stabilised solid compositions of factor VIIa polypeptides |
WO2004082708A2 (en) * | 2003-03-18 | 2004-09-30 | Novo Nordisk Health Care Ag | Liquid, aqueous, pharmaceutical compositions of factor vii polypeptides |
US7897734B2 (en) * | 2003-03-26 | 2011-03-01 | Novo Nordisk Healthcare Ag | Method for the production of proteins |
RU2364609C2 (ru) * | 2003-05-23 | 2009-08-20 | Ново Нордиск Хелт Кэр Аг | Стабилизация белка в растворе |
CN1318087C (zh) * | 2003-06-06 | 2007-05-30 | 北京三诺佳邑生物技术有限责任公司 | 去白蛋白神经生长因子制剂 |
ES2382157T3 (es) * | 2003-06-25 | 2012-06-05 | Novo Nordisk Health Care Ag | Composición líquida de polipépttidos del factor VII |
DE602004023848D1 (de) * | 2003-07-01 | 2009-12-10 | Novo Nordisk Healthcare Ag | Von factor vii polypeptiden |
CA2534028A1 (en) * | 2003-08-14 | 2005-02-24 | Novo Nordisk Health Care Ag | Liquid, aqueous pharmaceutical composition of factor vii polypeptides |
EP1703899B1 (en) * | 2003-12-19 | 2011-05-04 | Novo Nordisk Health Care AG | Stabilised compositions of factor vii polypeptides |
US8168222B2 (en) | 2004-09-07 | 2012-05-01 | Board Of Regents Of The University Of Nebraska | Amphiphilic polymer-protein conjugates and methods of use thereof |
US8017151B2 (en) * | 2004-09-07 | 2011-09-13 | Board Of Regents Of The University Of Nebraska By And Behalf Of The University Of Nebraska Medical Center | Amphiphilic polymer-protein conjugates and methods of use thereof |
US20090325978A1 (en) * | 2006-08-14 | 2009-12-31 | Katsumi Onai | Stable lyophilized preparation |
ES2407413T3 (es) * | 2006-11-08 | 2013-06-12 | P Mind Co., Ltd | Aparato para acelerar la producción de factor neurotrófico |
EP1958618A1 (de) | 2007-02-15 | 2008-08-20 | Octapharma AG | Verfahren zur Gefriertrocknung mit optimierter Rekonstitution von Biopolymeren |
RU2498820C2 (ru) * | 2008-09-26 | 2013-11-20 | Адосиа | Комплекс, образованный полисахаридом и нвр |
CN102232932B (zh) * | 2010-04-27 | 2013-06-05 | 重庆莱美药业股份有限公司 | 果胶-阿霉素轭合物的冻干制剂及制备方法 |
BR112013025892B1 (pt) | 2011-04-07 | 2021-01-19 | Neovacs | produto imunogênico, forma de dosagem unitária, dispositivo médico e kit relacionados a ifna |
US20150005236A1 (en) * | 2012-02-08 | 2015-01-01 | Institut National De La Recherche Agronomique | Use of beta-nerve growth factor for inducing ovulation in mammals |
EP3287140B1 (en) * | 2015-04-21 | 2021-06-02 | Staidson (Beijing) Biopharmaceuticals Co., Ltd. | Nerve growth factor composition and powder injection |
EP3287139B1 (en) * | 2015-04-21 | 2021-08-11 | Staidson (Beijing) Biopharmaceuticals Co., Ltd. | Nerve growth factor composition and injection powder |
DK3287141T3 (da) * | 2015-04-21 | 2021-10-11 | Staidson Beijing Biopharmaceuticals Co Ltd | Nervevækstfaktorsammensætning og injektionspulver |
US9868828B2 (en) * | 2015-06-23 | 2018-01-16 | Amolifescience Co., Ltd. | Defined three-dimensional microenvironment for stem cell |
KR20180123559A (ko) | 2016-03-25 | 2018-11-16 | 아스텔라스세이야쿠 가부시키가이샤 | PEG화 항인간 NGF 항체 Fab' 프래그먼트 함유 의약 조성물 |
ES2905874T3 (es) * | 2016-06-01 | 2022-04-12 | Servier Ip Uk Ltd | Formulaciones de óxido de polialquileno-asparaginasa y métodos para elaborar y usar las mismas |
CN109260147B (zh) * | 2018-10-15 | 2019-09-13 | 珠海亿胜生物制药有限公司 | 一种用于治疗或预防神经损伤的重组人碱性成纤维细胞生长因子注射剂 |
US11767504B2 (en) | 2020-08-14 | 2023-09-26 | Albcura Corporation | Albumin compositions and methods of producing and using same |
IL302317A (en) | 2020-10-28 | 2023-06-01 | Dompe Farm Spa | Pharmaceutical packaging including polypropylene containers and aqueous formulations of NGF packed in them |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ222413A (en) | 1986-11-05 | 1991-06-25 | Ethicon Inc | Compositions containing a polypeptide growth factor and a water-soluble cellulose polymer stabiliser |
NZ226170A (en) * | 1987-09-18 | 1990-07-26 | Ethicon Inc | Stable freeze-dried pharmaceutical composition containing epidermal growth factor |
IT1219874B (it) * | 1988-03-18 | 1990-05-24 | Fidia Farmaceutici | Utilizzazione del fattore di crescita nervoso umano e sue composizioni farmaceutiche |
US5096885A (en) | 1988-04-15 | 1992-03-17 | Genentech, Inc. | Human growth hormone formulation |
JPH0418031A (ja) * | 1989-02-16 | 1992-01-22 | Hiroshi Saito | 損傷治癒促進剤 |
JP3283288B2 (ja) * | 1991-03-08 | 2002-05-20 | 電気化学工業株式会社 | 生理活性ペプチド製剤 |
JP2818834B2 (ja) * | 1991-08-12 | 1998-10-30 | 大塚製薬株式会社 | IL−1α安定化医薬製剤 |
-
1993
- 1993-08-20 US US08/109,798 patent/US6277828B1/en not_active Expired - Lifetime
-
1994
- 1994-08-16 DE DE69431562T patent/DE69431562T2/de not_active Expired - Lifetime
- 1994-08-16 CZ CZ1996424A patent/CZ292422B6/cs not_active IP Right Cessation
- 1994-08-16 WO PCT/US1994/009245 patent/WO1995005845A1/en active IP Right Grant
- 1994-08-16 BR BR9407278A patent/BR9407278A/pt not_active Application Discontinuation
- 1994-08-16 UA UA96020622A patent/UA43348C2/uk unknown
- 1994-08-16 NZ NZ271873A patent/NZ271873A/en not_active IP Right Cessation
- 1994-08-16 DK DK94925903T patent/DK0721343T3/da active
- 1994-08-16 CN CNB94193148XA patent/CN1163265C/zh not_active Expired - Lifetime
- 1994-08-16 PL PL94313084A patent/PL176387B1/pl unknown
- 1994-08-16 ES ES94925903T patent/ES2181723T3/es not_active Expired - Lifetime
- 1994-08-16 CA CA002169834A patent/CA2169834C/en not_active Expired - Lifetime
- 1994-08-16 RO RO96-00301A patent/RO114742B1/ro unknown
- 1994-08-16 SK SK183-96A patent/SK284064B6/sk not_active IP Right Cessation
- 1994-08-16 RU RU96105951A patent/RU2126265C1/ru active
- 1994-08-16 AU AU75668/94A patent/AU677699B2/en not_active Expired
- 1994-08-16 AT AT94925903T patent/ATE226085T1/de active
- 1994-08-16 SI SI9420048A patent/SI9420048B/sl unknown
- 1994-08-16 KR KR1020017005635A patent/KR100341193B1/ko not_active IP Right Cessation
- 1994-08-16 PT PT94925903T patent/PT721343E/pt unknown
- 1994-08-16 JP JP50764495A patent/JP4592830B2/ja not_active Expired - Lifetime
- 1994-08-16 EP EP94925903A patent/EP0721343B1/en not_active Expired - Lifetime
- 1994-08-16 HU HU9600371A patent/HU228152B1/hu unknown
- 1994-08-19 ZA ZA946333A patent/ZA946333B/xx unknown
- 1994-08-19 IL IL11072594A patent/IL110725A/en not_active IP Right Cessation
- 1994-08-19 IL IL124941A patent/IL124941A/en not_active IP Right Cessation
- 1994-08-30 TW TW083107604A patent/TW427905B/zh not_active IP Right Cessation
-
1996
- 1996-02-19 BG BG100371A patent/BG62951B1/bg unknown
- 1996-02-19 LT LT96-011A patent/LT4051B/lt not_active IP Right Cessation
- 1996-02-19 NO NO19960651A patent/NO317627B1/no not_active IP Right Cessation
- 1996-02-19 LV LVP-96-48A patent/LV11279B/en unknown
- 1996-02-19 FI FI960750A patent/FI113241B/fi not_active IP Right Cessation
-
1998
- 1998-06-16 IL IL12494198A patent/IL124941A0/xx active IP Right Grant
- 1998-12-19 HK HK98114132A patent/HK1012990A1/xx not_active IP Right Cessation
-
2001
- 2001-02-20 US US09/789,855 patent/US7074763B2/en not_active Expired - Fee Related
-
2007
- 2007-08-08 JP JP2007206876A patent/JP2007314572A/ja active Pending
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PT721343E (pt) | Formulacoes farmaceuticas de factor de crescimento do tecido nervoso | |
AU2789989A (en) | Acylated uridine and cytidine and uses thereof | |
FI875533A (fi) | Insulinpreparat foer non-parenteral dosering. | |
CA2068324A1 (en) | Metal-peptide compositions and methods for stimulating hair growth | |
IT1232827B (it) | Proteine biologicamente attive, formulazioni che le contengono e metodo per prepararle ed applicarle | |
EA199900553A1 (ru) | Чрескожная терапевтическая система | |
BR9611571A (pt) | Composição farmacêutica estável composição farmacêutica kit para administração de ngf e método de aumento da estabilidade de ngf | |
ES2151607T3 (es) | Factor 12 de crecimiento y de diferenciacion. | |
CA2222698A1 (fr) | Utilisation d'antagonistes de la bradykinine pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute | |
ES2002083A6 (es) | Un metodo para preparar derivados de piroglutamida | |
AU2062288A (en) | Combination of pyrimidine derivatives and retinoids, as separate components, for inducing and stimulating hair growth and reducing its loss | |
ATE306278T1 (de) | Behandlung von knochenleiden mit adrenomedullin | |
DE3777411D1 (de) | Mittel zur verbesserung der perkutanen verabreichung von arzneimitteln. | |
ES2062361T3 (es) | Composicion cosmetica. | |
UA5743C2 (uk) | Препарат тканинних біологічно активних речовин, який має регенаторну дію, та спосіб його одержання | |
WO2000022097A3 (en) | Periferal blood mensenchymal precursor cells | |
NO894972L (no) | Polypeptidforbindelser med veksthormon-frigjoerende aktivitet. | |
IT8921516A0 (it) | Procedimento di microincapsulazione di microorganismi vivi e composizioni farmaceutiche stabili. |