ES2151607T3 - Factor 12 de crecimiento y de diferenciacion. - Google Patents
Factor 12 de crecimiento y de diferenciacion.Info
- Publication number
- ES2151607T3 ES2151607T3 ES95928062T ES95928062T ES2151607T3 ES 2151607 T3 ES2151607 T3 ES 2151607T3 ES 95928062 T ES95928062 T ES 95928062T ES 95928062 T ES95928062 T ES 95928062T ES 2151607 T3 ES2151607 T3 ES 2151607T3
- Authority
- ES
- Spain
- Prior art keywords
- differentiation factor
- growth
- polyucleotidic
- amino acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 102000000429 Factor XII Human genes 0.000 title abstract 2
- 108010080865 Factor XII Proteins 0.000 title abstract 2
- 230000004069 differentiation Effects 0.000 title abstract 2
- 150000001413 amino acids Chemical group 0.000 abstract 2
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
SE DESCRIBE EL FACTOR-12 DE DIFERENCIACION DEL CRECIMIENTO, JUNTO CON SU SECUENCIA POLINUCLEOTIDICA Y SU SECUENCIA AMINOACIDA. ASIMISMO, SE DESCRIBEN METODOS TERAPEUTICOS Y DE DIAGNOSTICO, PARA UTILIZAR LAS SECUENCIA POLINUCLEOTIDICA Y AMINOACIDA DE GDF-12.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/274,215 US5831054A (en) | 1994-07-13 | 1994-07-13 | Polynucleotide encoding growth differentiation factor-12 |
US31137094A | 1994-09-26 | 1994-09-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2151607T3 true ES2151607T3 (es) | 2001-01-01 |
Family
ID=26956672
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES95928062T Expired - Lifetime ES2151607T3 (es) | 1994-07-13 | 1995-07-12 | Factor 12 de crecimiento y de diferenciacion. |
Country Status (11)
Country | Link |
---|---|
US (1) | US5929213A (es) |
EP (1) | EP0770089B1 (es) |
JP (1) | JPH10503362A (es) |
AT (1) | ATE196147T1 (es) |
CA (1) | CA2195246A1 (es) |
DE (1) | DE69518760T2 (es) |
DK (1) | DK0770089T3 (es) |
ES (1) | ES2151607T3 (es) |
GR (1) | GR3034772T3 (es) |
PT (1) | PT770089E (es) |
WO (1) | WO1996002559A1 (es) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5846770A (en) * | 1994-11-22 | 1998-12-08 | Genetics Institute, Inc. | DNA molecules encoding human chordin |
US5965403A (en) | 1996-09-18 | 1999-10-12 | Genetics Institute, Inc. | Nucleic acids encoding bone morphogenic protein-16 (BMP-16) |
US20020052026A1 (en) | 1997-10-08 | 2002-05-02 | Steven M. Vicik | Methods of refolding proteins |
US6027917A (en) | 1997-12-10 | 2000-02-22 | Genetics Institute, Inc. | Bone morphogenetic protein (BMP)-17 and BMP-18 compositions |
US6727224B1 (en) | 1999-02-01 | 2004-04-27 | Genetics Institute, Llc. | Methods and compositions for healing and repair of articular cartilage |
IL150198A0 (en) * | 1999-12-15 | 2002-12-01 | Res Dev Foundation | Betaglycan as an inhibin receptor and uses thereof |
TWI267378B (en) | 2001-06-08 | 2006-12-01 | Wyeth Corp | Calcium phosphate delivery vehicles for osteoinductive proteins |
BRPI0413720A (pt) | 2003-09-12 | 2006-10-17 | Wyeth Corp | bastões e pastas sólidas de fosfato de cálcio injetável para liberação de proteìnas osteogênicas |
CA2563374A1 (en) | 2004-04-27 | 2005-12-08 | Research Development Foundation | Antagonism of tgf-.beta.superfamily receptor signaling |
US7799754B2 (en) | 2004-10-14 | 2010-09-21 | Biomimetic Therapeutics, Inc. | Compositions and methods for treating bone |
US7473678B2 (en) | 2004-10-14 | 2009-01-06 | Biomimetic Therapeutics, Inc. | Platelet-derived growth factor compositions and methods of use thereof |
US8147860B2 (en) | 2005-12-06 | 2012-04-03 | Etex Corporation | Porous calcium phosphate bone material |
ES2664229T3 (es) | 2006-06-30 | 2018-04-18 | Biomimetic Therapeutics, Llc | Composiciones y métodos de biomatriz-PDGF para el tratamiento de lesiones del manguito rotador |
US9161967B2 (en) | 2006-06-30 | 2015-10-20 | Biomimetic Therapeutics, Llc | Compositions and methods for treating the vertebral column |
US8524265B2 (en) | 2006-08-17 | 2013-09-03 | Warsaw Orthopedic, Inc. | Medical implant sheets useful for tissue regeneration |
BR122020000059B8 (pt) | 2008-09-09 | 2021-06-22 | Biomimetic Therapeutics Inc | composição que compreende uma matriz biocompatível e um fator de crescimento derivado de plaqueta e kit |
US8609127B2 (en) | 2009-04-03 | 2013-12-17 | Warsaw Orthopedic, Inc. | Medical implant with bioactive material and method of making the medical implant |
US20110002897A1 (en) | 2009-06-11 | 2011-01-06 | Burnham Institute For Medical Research | Directed differentiation of stem cells |
WO2011103598A1 (en) | 2010-02-22 | 2011-08-25 | Biomimetic Therapeutics, Inc. | Platelet-derived growth factor compositions and methods for the treatment of tendinopathies |
US10034945B2 (en) | 2012-07-13 | 2018-07-31 | Trustees Of Tufts College | Silk powder compaction for production of constructs with high mechanical strength and stiffness |
CN115073625B (zh) | 2015-10-26 | 2024-01-16 | 哈佛学院院长等 | 还原和氧化的多糖及其使用方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3193050B2 (ja) * | 1992-02-12 | 2001-07-30 | ビオファルム ゲゼルシャフト ツア ビオテヒノロ ギッシェン エントヴィックルング フォン ファル マカ ミット ベシュレンクテル ハフツング | 新規の増殖/分化因子をコード化するdna配列 |
-
1995
- 1995-07-12 CA CA002195246A patent/CA2195246A1/en not_active Abandoned
- 1995-07-12 DK DK95928062T patent/DK0770089T3/da active
- 1995-07-12 EP EP95928062A patent/EP0770089B1/en not_active Expired - Lifetime
- 1995-07-12 JP JP7523725A patent/JPH10503362A/ja active Pending
- 1995-07-12 WO PCT/US1995/008745 patent/WO1996002559A1/en active IP Right Grant
- 1995-07-12 PT PT95928062T patent/PT770089E/pt unknown
- 1995-07-12 US US08/765,662 patent/US5929213A/en not_active Expired - Fee Related
- 1995-07-12 AT AT95928062T patent/ATE196147T1/de not_active IP Right Cessation
- 1995-07-12 DE DE69518760T patent/DE69518760T2/de not_active Expired - Fee Related
- 1995-07-12 ES ES95928062T patent/ES2151607T3/es not_active Expired - Lifetime
-
2000
- 2000-11-07 GR GR20000402461T patent/GR3034772T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE69518760D1 (de) | 2000-10-12 |
WO1996002559A1 (en) | 1996-02-01 |
CA2195246A1 (en) | 1996-02-01 |
EP0770089A1 (en) | 1997-05-02 |
DK0770089T3 (da) | 2000-10-23 |
EP0770089A4 (en) | 1997-06-18 |
EP0770089B1 (en) | 2000-09-06 |
DE69518760T2 (de) | 2001-05-23 |
PT770089E (pt) | 2001-02-28 |
US5929213A (en) | 1999-07-27 |
JPH10503362A (ja) | 1998-03-31 |
ATE196147T1 (de) | 2000-09-15 |
GR3034772T3 (en) | 2001-02-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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