US2779780A
(en)
|
1955-03-01 |
1957-01-29 |
Du Pont |
1, 4-diamino-2, 3-dicyano-1, 4-bis (substituted mercapto) butadienes and their preparation
|
US5114946A
(en)
|
1987-06-12 |
1992-05-19 |
American Cyanamid Company |
Transdermal delivery of pharmaceuticals
|
US4818541A
(en)
|
1987-08-19 |
1989-04-04 |
Schering Corporation |
Transdermal delivery of enantiomers of phenylpropanolamine
|
US7196170B2
(en)
|
1992-09-14 |
2007-03-27 |
The General Hospital Corporation |
Aiolos, Helios, Daedalos and Ikaros: genes, polypeptides, regulatory elements and uses thereof
|
US5262564A
(en)
|
1992-10-30 |
1993-11-16 |
Octamer, Inc. |
Sulfinic acid adducts of organo nitroso compounds useful as retroviral inactivating agents anti-retroviral agents and anti-tumor agents
|
EP1143957A3
(en)
|
1998-12-16 |
2002-02-27 |
Warner-Lambert Company |
Treatment of arthritis with mek inhibitors
|
CA3016482A1
(en)
|
1999-11-30 |
2001-06-07 |
Mayo Foundation For Medical Education And Research |
B7-h1, a novel immunoregulatory molecule
|
SI1301472T1
(sl)
|
2000-07-19 |
2014-05-30 |
Warner-Lambert Company Llc |
Oksigenirani estri 4-jodo fenilamino benzihidroksamskih kislin
|
AU2001291195A1
(en)
|
2000-12-01 |
2002-06-11 |
Parker Hughes Institute |
Nucleotide and protein sequence of helios 3 and methods of use
|
US7153867B2
(en)
|
2001-08-06 |
2006-12-26 |
Celgene Corporation |
Use of nitrogen substituted thalidomide analogs for the treatment of macular degenerator
|
CN100522967C
(zh)
|
2002-02-01 |
2009-08-05 |
阿里亚德基因治疗公司 |
含磷化合物及其应用
|
EP2308861B1
(en)
|
2002-03-08 |
2017-03-01 |
Eisai R&D Management Co., Ltd. |
Macrocyclic compounds useful as pharmaceuticals
|
TWI275390B
(en)
|
2002-04-30 |
2007-03-11 |
Wyeth Corp |
Process for the preparation of 7-substituted-3- quinolinecarbonitriles
|
EP3287144A1
(en)
|
2002-07-03 |
2018-02-28 |
ONO Pharmaceutical Co., Ltd. |
Immunopotentiating compositions
|
GB0215823D0
(en)
|
2002-07-09 |
2002-08-14 |
Astrazeneca Ab |
Quinazoline derivatives
|
ES2318167T3
(es)
|
2002-07-15 |
2009-05-01 |
The Trustees Of Princeton University |
Compuestos de union a iap.
|
US20040087558A1
(en)
|
2002-10-24 |
2004-05-06 |
Zeldis Jerome B. |
Methods of using and compositions comprising selective cytokine inhibitory drugs for treatment, modification and management of pain
|
US20050203142A1
(en)
|
2002-10-24 |
2005-09-15 |
Zeldis Jerome B. |
Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of pain
|
CN101899114A
(zh)
|
2002-12-23 |
2010-12-01 |
惠氏公司 |
抗pd-1抗体及其用途
|
US7399865B2
(en)
|
2003-09-15 |
2008-07-15 |
Wyeth |
Protein tyrosine kinase enzyme inhibitors
|
US7612096B2
(en)
|
2003-10-23 |
2009-11-03 |
Celgene Corporation |
Methods for treatment, modification and management of radiculopathy using 1-oxo-2-(2,6-dioxopiperidin-3yl)-4-aminoisoindoline
|
JP2007522116A
(ja)
|
2004-01-16 |
2007-08-09 |
ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン |
コンホメーションが制約されたSmac模倣物およびその使用
|
JP2007523061A
(ja)
|
2004-01-16 |
2007-08-16 |
ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン |
Smacペプチドミメティクスおよびその使用法
|
EP1740173A4
(en)
|
2004-03-23 |
2009-05-27 |
Genentech Inc |
AZABICYCLOOCTAN IAP INHIBITORS
|
JP4691549B2
(ja)
|
2004-04-07 |
2011-06-01 |
ノバルティス アーゲー |
Iapの阻害剤
|
US20070161696A1
(en)
|
2004-04-23 |
2007-07-12 |
Zeldis Jerome B |
Methods of using and compositions comprising selective cytokine inhibitory drugs for treatment, modification and management of pain
|
KR100984459B1
(ko)
|
2004-07-02 |
2010-09-29 |
제넨테크, 인크. |
Iap의 억제제
|
WO2006010118A2
(en)
|
2004-07-09 |
2006-01-26 |
The Regents Of The University Of Michigan |
Conformationally constrained smac mimetics and the uses thereof
|
WO2006017295A2
(en)
|
2004-07-12 |
2006-02-16 |
Idun Pharmaceuticals, Inc. |
Tetrapeptide analogs
|
CA2574040C
(en)
|
2004-07-15 |
2014-05-06 |
Tetralogic Pharmaceuticals Corporation |
Iap binding compounds
|
WO2006028964A1
(en)
|
2004-09-03 |
2006-03-16 |
Celgene Corporation |
Processes for the preparation of substituted 2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolines
|
JP4731867B2
(ja)
|
2004-10-01 |
2011-07-27 |
国立大学法人三重大学 |
Cd8陽性の細胞傷害性tリンパ球の誘導方法
|
JP5775245B2
(ja)
|
2004-12-01 |
2015-09-09 |
セルジーン コーポレイション |
免疫不全障害の治療のために免疫調節化合物を用いる方法及び組成物
|
JP2008524986A
(ja)
|
2004-12-10 |
2008-07-17 |
バイエル・ヘルスケア・アクチェンゲゼルシャフト |
タキサンに基づく薬物療法に対する悪性腫瘍の応答予測に有用な遺伝子変化
|
ATE477254T1
(de)
|
2004-12-20 |
2010-08-15 |
Genentech Inc |
Pyrrolidine als inhibitoren von iap
|
ES2432091T5
(es)
|
2005-03-25 |
2022-03-18 |
Gitr Inc |
Moléculas de unión GITR y usos de las mismas
|
CA2970873C
(en)
|
2005-05-09 |
2022-05-17 |
E. R. Squibb & Sons, L.L.C. |
Human monoclonal antibodies to programmed death 1 (pd-1) and methods for treating cancer using anti-pd-1 antibodies alone or in combination with other immunotherapeutics
|
CN104356236B
(zh)
|
2005-07-01 |
2020-07-03 |
E.R.施贵宝&圣斯有限责任公司 |
抗程序性死亡配体1(pd-l1)的人单克隆抗体
|
CA2618218C
(en)
|
2005-07-21 |
2015-06-30 |
Ardea Biosciences, Inc. |
N-(arylamino)-sulfonamide inhibitors of mek
|
US20070128636A1
(en)
|
2005-12-05 |
2007-06-07 |
Baker Joffre B |
Predictors Of Patient Response To Treatment With EGFR Inhibitors
|
KR20080097190A
(ko)
|
2005-12-29 |
2008-11-04 |
안트로제네시스 코포레이션 |
태반 줄기세포의 수집과 보존을 위한 개선된 조성물과 이조성물의 이용 방법
|
US20070269827A1
(en)
|
2006-05-18 |
2007-11-22 |
Oklahoma Medical Research Foundation |
Predicting and Diagnosing Patients With Autoimmune Disease
|
KR101342035B1
(ko)
|
2006-06-20 |
2013-12-16 |
한국과학기술연구원 |
신장독성 및 부작용 유발 약물 검색용 바이오마커 및 이를이용한 신장독성 및 부작용 유발 약물 검색 방법
|
US8877780B2
(en)
|
2006-08-30 |
2014-11-04 |
Celgene Corporation |
5-substituted isoindoline compounds
|
AR065810A1
(es)
*
|
2007-03-20 |
2009-07-01 |
Celgene Corp |
Derivados de isoindolina 4'-o-sustituidos,composiciones farmaceuticas que los comprenden y usos de los mismos en el tratamiento del cancer y en otros trastornos donde es necesario el control de la angiogenesis o la inhibicion de citoquinas, incluyendo tnf-alfa.
|
MX2009011783A
(es)
|
2007-04-30 |
2009-12-04 |
Genentech Inc |
Inhibidores de iap.
|
US9244059B2
(en)
|
2007-04-30 |
2016-01-26 |
Immutep Parc Club Orsay |
Cytotoxic anti-LAG-3 monoclonal antibody and its use in the treatment or prevention of organ transplant rejection and autoimmune disease
|
EP1987839A1
(en)
|
2007-04-30 |
2008-11-05 |
I.N.S.E.R.M. Institut National de la Sante et de la Recherche Medicale |
Cytotoxic anti-LAG-3 monoclonal antibody and its use in the treatment or prevention of organ transplant rejection and autoimmune disease
|
EP3222634A1
(en)
|
2007-06-18 |
2017-09-27 |
Merck Sharp & Dohme B.V. |
Antibodies to human programmed death receptor pd-1
|
PE20140100A1
(es)
|
2007-09-12 |
2014-02-12 |
Genentech Inc |
Combinaciones de compuestos inhibidores de fosfoinositida 3-quinasa y agentes quimioterapeuticos
|
EP2044949A1
(en)
|
2007-10-05 |
2009-04-08 |
Immutep |
Use of recombinant lag-3 or the derivatives thereof for eliciting monocyte immune response
|
JP2009092508A
(ja)
|
2007-10-09 |
2009-04-30 |
Norihiro Nishimoto |
リウマチ治療剤の効果の予測方法
|
US8354528B2
(en)
|
2007-10-25 |
2013-01-15 |
Genentech, Inc. |
Process for making thienopyrimidine compounds
|
EP2227558A1
(en)
|
2007-11-30 |
2010-09-15 |
GlaxoSmithKline Biologicals SA |
Method for classifying cancer patients as responder or non-responder to immunotherapy
|
KR100957051B1
(ko)
|
2007-12-28 |
2010-05-13 |
한국과학기술연구원 |
니트로푸란토인 처리에 따른, 폐독성 유발 약물 검색용마커유전자 및 이를 이용한 검색 방법
|
GB2456390A
(en)
|
2008-01-15 |
2009-07-22 |
Glaxo Group Ltd |
Bipolar disorder treatments
|
WO2009094592A2
(en)
|
2008-01-23 |
2009-07-30 |
Perlegen Sciences, Inc. |
Genetic basis of alzheimer's disease and diagnosis and treatment thereof
|
US8747847B2
(en)
|
2008-02-11 |
2014-06-10 |
Curetech Ltd. |
Monoclonal antibodies for tumor treatment
|
EP2262837A4
(en)
|
2008-03-12 |
2011-04-06 |
Merck Sharp & Dohme |
PD-1 BINDING PROTEINS
|
US20090307179A1
(en)
|
2008-03-19 |
2009-12-10 |
Brandon Colby |
Genetic analysis
|
US20110229498A1
(en)
|
2008-05-08 |
2011-09-22 |
The Johns Hopkins University |
Compositions and methods for modulating an immune response
|
US8168784B2
(en)
|
2008-06-20 |
2012-05-01 |
Abbott Laboratories |
Processes to make apoptosis promoters
|
AR072999A1
(es)
|
2008-08-11 |
2010-10-06 |
Medarex Inc |
Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos
|
WO2010027423A2
(en)
|
2008-08-25 |
2010-03-11 |
Amplimmune, Inc. |
Compositions of pd-1 antagonists and methods of use
|
KR20110074850A
(ko)
|
2008-08-25 |
2011-07-04 |
앰플리뮨, 인크. |
Pd-1 길항제 및 그의 사용 방법
|
CA2736829C
(en)
|
2008-09-12 |
2018-02-27 |
Isis Innovation Limited |
Pd-1 specific antibodies and uses thereof
|
AU2009296392B2
(en)
|
2008-09-26 |
2016-06-02 |
Dana-Farber Cancer Institute, Inc. |
Human anti-PD-1, PD-L1, and PD-L2 antibodies and uses therefor
|
EP2177615A1
(en)
|
2008-10-10 |
2010-04-21 |
Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. |
Method for a genome wide identification of expression regulatory sequences and use of genes and molecules derived thereof for the diagnosis and therapy of metabolic and/or tumorous diseases
|
PE20140963A1
(es)
|
2008-10-29 |
2014-08-06 |
Celgene Corp |
Compuestos de isoindolina para el tratamiento de cancer
|
PE20120341A1
(es)
|
2008-12-09 |
2012-04-24 |
Genentech Inc |
Anticuerpos anti-pd-l1 y su uso para mejorar la funcion de celulas t
|
WO2010089411A2
(en)
|
2009-02-09 |
2010-08-12 |
Universite De La Mediterranee |
Pd-1 antibodies and pd-l1 antibodies and uses thereof
|
US9212177B2
(en)
|
2009-08-05 |
2015-12-15 |
Versitech Limited |
Antiviral compounds and methods of making and using thereof
|
AU2010281265A1
(en)
|
2009-08-05 |
2012-03-22 |
Versitech Limited |
Antiviral compounds and methods of making and using thereof
|
US8709424B2
(en)
|
2009-09-03 |
2014-04-29 |
Merck Sharp & Dohme Corp. |
Anti-GITR antibodies
|
WO2011056505A1
(en)
|
2009-10-26 |
2011-05-12 |
Abbott Laboratories |
Detection of chromosomal abnormalities associated with prognosis of non small cell lung cancer
|
WO2011066342A2
(en)
|
2009-11-24 |
2011-06-03 |
Amplimmune, Inc. |
Simultaneous inhibition of pd-l1/pd-l2
|
KR101573109B1
(ko)
|
2009-11-24 |
2015-12-01 |
메디뮨 리미티드 |
B7―h1에 대한 표적화된 결합 물질
|
RS58523B1
(sr)
*
|
2010-02-11 |
2019-04-30 |
Celgene Corp |
Derivati arilmetoksi izoindolina i kombinacije koje ih obuhvataju i postupci njihove upotrebe
|
CA2791930A1
(en)
|
2010-03-11 |
2011-09-15 |
Kerry Louise Tyson |
Pd-1 antibody
|
EP2569446B1
(en)
|
2010-05-12 |
2018-07-11 |
Steven E. Schutzer |
Diagnostic markers for neuropsychiatric diseasen
|
US20120149715A1
(en)
|
2010-05-28 |
2012-06-14 |
Yi Tsun Richard Kao |
Compounds and methods for the treatment of viral infections
|
WO2011151941A1
(ja)
|
2010-06-04 |
2011-12-08 |
国立大学法人東京大学 |
制御性t細胞の増殖または集積を誘導する作用を有する組成物
|
KR101846590B1
(ko)
|
2010-06-11 |
2018-04-09 |
교와 핫꼬 기린 가부시키가이샤 |
항 tim-3 항체
|
WO2011159877A2
(en)
|
2010-06-18 |
2011-12-22 |
The Brigham And Women's Hospital, Inc. |
Bi-specific antibodies against tim-3 and pd-1 for immunotherapy in chronic immune conditions
|
US8907053B2
(en)
|
2010-06-25 |
2014-12-09 |
Aurigene Discovery Technologies Limited |
Immunosuppression modulating compounds
|
US20130281304A1
(en)
|
2010-08-13 |
2013-10-24 |
Andrew P. Feinberg |
Comprehensive Methylome Map of Myeloid and Lymphoid Commitment from Hematopoietic Proenitors
|
CA2815000A1
(en)
|
2010-10-22 |
2012-04-26 |
Dana-Farber Cancer Institute, Inc. |
Discovery of regulatory t cells programmed to suppress an immune response
|
CA2833636A1
(en)
|
2011-04-20 |
2012-10-26 |
Amplimmune, Inc. |
Antibodies and other molecules that bind b7-h1 and pd-1
|
AU2012268036B2
(en)
|
2011-06-06 |
2017-04-06 |
THE UNITED STATES OF AMERICA as represented by THE SECRETARY OF STATE OF THE DEPARTMENT OF VETERANS AFFAIRS |
Methods of inhibiting muscle atrophy
|
WO2012175613A1
(en)
|
2011-06-21 |
2012-12-27 |
Innate Pharma |
NKp46-MEDIATED NK CELL TUNING
|
BR112013033988B1
(pt)
|
2011-07-01 |
2021-10-19 |
Beckman Coulter, Inc. |
Métodos de identificação e isolamento de uma ou mais populações de células t regulatórias imunossupressoras
|
WO2013006490A2
(en)
|
2011-07-01 |
2013-01-10 |
Cellerant Therapeutics, Inc. |
Antibodies that specifically bind to tim3
|
WO2013037118A1
(zh)
|
2011-09-16 |
2013-03-21 |
上海长海医院 |
前列腺癌的生物学标志物、治疗靶点及其用途
|
LT2785375T
(lt)
|
2011-11-28 |
2020-11-10 |
Merck Patent Gmbh |
Anti-pd-l1 antikūnai ir jų panaudojimas
|
EP3978598A1
(en)
|
2011-12-01 |
2022-04-06 |
The University of Tokyo |
Human-derived bacteria that induce proliferation or accumulation of regulatory t cells
|
US9481866B2
(en)
|
2011-12-16 |
2016-11-01 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Methods of producing T cell populations enriched for stable regulatory T-cells
|
WO2013098797A2
(en)
|
2011-12-31 |
2013-07-04 |
Kuriakose Moni Abraham |
Diagnostic tests for predicting prognosis, recurrence, resistance or sensitivity to therapy and metastatic status in cancer
|
CN104245923B
(zh)
|
2012-03-02 |
2018-04-20 |
加州大学评议会 |
同种异型抗原‑反应性调节t细胞的增殖
|
GB201207297D0
(en)
|
2012-04-26 |
2012-06-06 |
Senzagen Ab |
Analytical methods and arrays for use in the same
|
WO2013179174A1
(en)
|
2012-05-29 |
2013-12-05 |
Koninklijke Philips N.V. |
Lighting arrangement
|
CN115093480A
(zh)
|
2012-05-31 |
2022-09-23 |
索伦托药业有限公司 |
与pd-l1结合的抗原结合蛋白
|
GB201213571D0
(en)
|
2012-07-31 |
2012-09-12 |
Univ Leuven Kath |
Growth factor cocktail to enhnce osteogenic differentiayion of mesenchymal
|
EP2682750A1
(en)
|
2012-07-02 |
2014-01-08 |
Sotio a.s. |
In vitro method for the diagnosis and surveillance of cancer
|
UY34887A
(es)
|
2012-07-02 |
2013-12-31 |
Bristol Myers Squibb Company Una Corporacion Del Estado De Delaware |
Optimización de anticuerpos que se fijan al gen de activación de linfocitos 3 (lag-3) y sus usos
|
ES2848052T3
(es)
|
2012-08-03 |
2021-08-05 |
Dana Farber Cancer Inst Inc |
Anticuerpos de unión dual anti-PD-L1 y PD-L2 de agente individual y métodos de uso
|
KR20150054962A
(ko)
*
|
2012-09-10 |
2015-05-20 |
셀진 코포레이션 |
국소 진행성 유방암의 치료방법
|
WO2014055897A2
(en)
|
2012-10-04 |
2014-04-10 |
Dana-Farber Cancer Institute, Inc. |
Human monoclonal anti-pd-l1 antibodies and methods of use
|
EP2903692B1
(en)
|
2012-10-08 |
2019-12-25 |
St. Jude Children's Research Hospital |
Therapies based on control of regulatory t cell stability and function via a neuropilin-1:semaphorin axis
|
AR093984A1
(es)
|
2012-12-21 |
2015-07-01 |
Merck Sharp & Dohme |
Anticuerpos que se unen a ligando 1 de muerte programada (pd-l1) humano
|
US20160007893A1
(en)
|
2013-02-06 |
2016-01-14 |
Loxbridge Research Llp |
Systems and methods for early disease detection and real-time disease monitoring
|
JP2016513974A
(ja)
|
2013-03-14 |
2016-05-19 |
チルドレンズ メディカル センター コーポレーション |
造血幹細胞系列を初期化するための組成物および方法
|
AU2014230741B2
(en)
|
2013-03-15 |
2017-04-13 |
Glaxosmithkline Intellectual Property Development Limited |
Anti-LAG-3 binding proteins
|
CN105378104A
(zh)
|
2013-03-15 |
2016-03-02 |
威拉赛特公司 |
用于样品分类的方法和组合物
|
EP2992017B1
(en)
|
2013-05-02 |
2020-11-18 |
AnaptysBio, Inc. |
Antibodies directed against programmed death-1 (pd-1)
|
JP6563906B2
(ja)
|
2013-05-31 |
2019-08-21 |
ソレント・セラピューティクス・インコーポレイテッドSorrento Therapeutics, Inc. |
Pd−1に結合する抗原結合蛋白質
|
US20160122821A1
(en)
|
2013-06-10 |
2016-05-05 |
Suregene, Llc |
Genetic markers of antipsychotic response
|
WO2014209804A1
(en)
|
2013-06-24 |
2014-12-31 |
Biomed Valley Discoveries, Inc. |
Bispecific antibodies
|
AR097306A1
(es)
|
2013-08-20 |
2016-03-02 |
Merck Sharp & Dohme |
Modulación de la inmunidad tumoral
|
TW201605896A
(zh)
|
2013-08-30 |
2016-02-16 |
安美基股份有限公司 |
Gitr抗原結合蛋白
|
CA2923700A1
(en)
|
2013-09-09 |
2015-03-12 |
The Scripps Research Institute |
Methods and systems for analysis of organ transplantation
|
AU2013400609B9
(en)
|
2013-09-13 |
2020-03-05 |
Beigene Switzerland Gmbh |
Anti-PD1 antibodies and their use as therapeutics and diagnostics
|
WO2015050875A1
(en)
|
2013-10-01 |
2015-04-09 |
The Regents Of The University Of California |
Endometriosis classifier
|
UY35790A
(es)
|
2013-10-21 |
2015-05-29 |
Teva Pharma |
Marcadores genéticos que predicen la respuesta al acetato de glatiramer
|
AU2014339900B2
(en)
|
2013-10-25 |
2019-10-24 |
Dana-Farber Cancer Institute, Inc. |
Anti-PD-L1 monoclonal antibodies and fragments thereof
|
WO2015081158A1
(en)
|
2013-11-26 |
2015-06-04 |
Bristol-Myers Squibb Company |
Method of treating hiv by disrupting pd-1/pd-l1 signaling
|
CR20160319A
(es)
|
2013-12-12 |
2016-11-08 |
Jiangsu Hengrui Medicine Co |
Anticuerpo pd-1, fragmento de union al antigeno de este y uso médico de este
|
JP2017509319A
(ja)
|
2014-01-15 |
2017-04-06 |
カドモン コーポレイション,リミティド ライアビリティ カンパニー |
免疫調節剤
|
WO2015109212A1
(en)
|
2014-01-17 |
2015-07-23 |
Pfizer Inc. |
Anti-il-2 antibodies and compositions and uses thereof
|
WO2015107196A1
(en)
|
2014-01-20 |
2015-07-23 |
Institut Curie |
Use of thalidomide or analogs thereof for preventing neurologic disorders induced by brain irradiation
|
TWI681969B
(zh)
|
2014-01-23 |
2020-01-11 |
美商再生元醫藥公司 |
針對pd-1的人類抗體
|
TWI680138B
(zh)
|
2014-01-23 |
2019-12-21 |
美商再生元醫藥公司 |
抗pd-l1之人類抗體
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
EA201691361A1
(ru)
|
2014-01-28 |
2016-12-30 |
Бристол-Маерс Сквибб Компани |
Антитела к lag-3 для лечения гематологических злокачественных опухолей
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
ME03558B
(me)
|
2014-03-14 |
2020-07-20 |
Novartis Ag |
Molekuli anti-lag-3 antiтela i njihove upotrebe
|
US20180228907A1
(en)
|
2014-04-14 |
2018-08-16 |
Arvinas, Inc. |
Cereblon ligands and bifunctional compounds comprising the same
|
US20160058872A1
(en)
|
2014-04-14 |
2016-03-03 |
Arvinas, Inc. |
Imide-based modulators of proteolysis and associated methods of use
|
MX2016013563A
(es)
|
2014-04-14 |
2017-05-09 |
Arvinas Inc |
Moduladores de la proteolisis basados en imida y metodos de uso asociados.
|
NZ726513A
(en)
|
2014-05-28 |
2023-07-28 |
Memorial Sloan Kettering Cancer Center |
Anti-gitr antibodies and methods of use thereof
|
US9885721B2
(en)
|
2014-05-29 |
2018-02-06 |
Spring Bioscience Corporation |
PD-L1 antibodies and uses thereof
|
SG11201610074YA
(en)
|
2014-06-06 |
2016-12-29 |
Bristol Myers Squibb Co |
Antibodies against glucocorticoid-induced tumor necrosis factor receptor (gitr) and uses thereof
|
WO2015195163A1
(en)
|
2014-06-20 |
2015-12-23 |
R-Pharm Overseas, Inc. |
Pd-l1 antagonist fully human antibody
|
TWI693232B
(zh)
|
2014-06-26 |
2020-05-11 |
美商宏觀基因股份有限公司 |
與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
|
WO2016000619A1
(en)
|
2014-07-03 |
2016-01-07 |
Beigene, Ltd. |
Anti-pd-l1 antibodies and their use as therapeutics and diagnostics
|
JO3663B1
(ar)
|
2014-08-19 |
2020-08-27 |
Merck Sharp & Dohme |
الأجسام المضادة لمضاد lag3 وأجزاء ربط الأنتيجين
|
AU2015327781A1
(en)
|
2014-10-03 |
2017-04-20 |
Dana-Farber Cancer Institute, Inc. |
Glucocorticoid-induced tumor necrosis factor receptor (GITR) antibodies and methods of use thereof
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
CU20170052A7
(es)
|
2014-10-14 |
2017-11-07 |
Dana Farber Cancer Inst Inc |
Moléculas de anticuerpo que se unen a pd-l1
|
PT3643709T
(pt)
|
2014-10-30 |
2021-12-20 |
Kangpu Biopharmaceuticals Ltd |
Derivado, intermediário, método de preparação, composição farmacêutica de isoindolina e utilização dos mesmos
|
LT3215532T
(lt)
|
2014-11-06 |
2020-01-10 |
F. Hoffmann-La Roche Ag |
Anti-tim3 antikūnai ir jų naudojimo būdai
|
WO2016090273A1
(en)
|
2014-12-05 |
2016-06-09 |
Foundation Medicine, Inc. |
Multigene analysis of tumor samples
|
TWI595006B
(zh)
|
2014-12-09 |
2017-08-11 |
禮納特神經系統科學公司 |
抗pd-1抗體類和使用彼等之方法
|
EP3034620A1
(en)
|
2014-12-17 |
2016-06-22 |
Diaxonhit |
Compositions and methods for diagnosing thyroid cancer
|
WO2016103269A1
(en)
|
2014-12-23 |
2016-06-30 |
Ramot At Tel-Aviv University Ltd. |
Populations of neural progenitor cells and methods of producing and using same
|
WO2016111947A2
(en)
|
2015-01-05 |
2016-07-14 |
Jounce Therapeutics, Inc. |
Antibodies that inhibit tim-3:lilrb2 interactions and uses thereof
|
AU2016209321B2
(en)
|
2015-01-20 |
2019-05-09 |
Boehringer Ingelheim Animal Health USA Inc. |
Anthelmintic compounds, compositions and method of using thereof
|
EP3050570A1
(en)
|
2015-01-31 |
2016-08-03 |
Neurovision Pharma GmbH |
Pharmaceutical composition consisting of a combination of G-CSF with GM-CSF
|
WO2016140974A1
(en)
|
2015-03-01 |
2016-09-09 |
Novena Therapeutics Inc. |
Process for measuring tumor response to an initial oncology treatment
|
EP3265486A4
(en)
|
2015-03-06 |
2018-11-14 |
Sorrento Therapeutics, Inc. |
Antibody therapeutics that bind tim3
|
MA41867A
(fr)
|
2015-04-01 |
2018-02-06 |
Anaptysbio Inc |
Anticorps dirigés contre l'immunoglobuline de cellule t et protéine 3 de mucine (tim-3)
|
CA2986141C
(en)
|
2015-05-22 |
2020-07-28 |
Biotheryx, Inc. |
Compounds targeting proteins, compositions, methods, and uses thereof
|
WO2016196580A1
(en)
|
2015-06-02 |
2016-12-08 |
Celgene Corporation |
Methods for determining drug efficacy for treatment of cancer using ratios of cereblon associated proteins
|
CA2988119A1
(en)
|
2015-06-03 |
2016-12-08 |
Dana-Farber Cancer Institute, Inc. |
Methods to induce conversion of regulatory t cells into effector t cells for cancer immunotherapy
|
JP6812364B2
(ja)
|
2015-06-03 |
2021-01-13 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
癌診断用抗gitr抗体
|
AU2016270442C1
(en)
|
2015-06-04 |
2022-06-02 |
Arvinas Operations, Inc. |
Imide-based modulators of proteolysis and associated methods of use
|
BR112017028013A2
(pt)
|
2015-06-22 |
2018-08-28 |
Harvard College |
indução de células t regulatórias da lâmina própria
|
CA2992298A1
(en)
|
2015-07-23 |
2017-01-26 |
Inhibrx Lp |
Multivalent and multispecific gitr-binding fusion proteins
|
RU2018108236A
(ru)
|
2015-08-12 |
2019-09-12 |
Медиммьюн Лимитед |
Слитые белки на основе gitrl и пути их применения
|
WO2017042337A1
(en)
|
2015-09-09 |
2017-03-16 |
Max-Delbrück-Centrum Für Molekulare Medizin In Der Helmhotz-Gemeinschaft |
Short-chain fatty acids for use in the treatment of cardiovascular disease
|
WO2017044979A2
(en)
|
2015-09-11 |
2017-03-16 |
Ventria Bioscience Inc. |
Lactoferrin compositions and methods for modulation of t cell subtypes and treatment of autoimmune diseases
|
US10954300B2
(en)
|
2015-09-28 |
2021-03-23 |
The Trustees Of Columbia University In The City Of New York |
Use of pentoxifylline with immune checkpoint-blockade therapies for the treatment of melanoma
|
AU2016330967B2
(en)
|
2015-09-30 |
2021-03-25 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Thalidomide analogs and methods of use
|
WO2017075465A1
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by detecting and targeting gata3
|
EP3368689B1
(en)
|
2015-10-28 |
2020-06-17 |
The Broad Institute, Inc. |
Composition for modulating immune responses by use of immune cell gene signature
|
WO2017075451A1
(en)
|
2015-10-28 |
2017-05-04 |
The Broad Institute Inc. |
Compositions and methods for evaluating and modulating immune responses by detecting and targeting pou2af1
|
US11090373B2
(en)
|
2015-12-04 |
2021-08-17 |
The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. |
Antigen-specific T cells for inducing immune tolerance
|
US20190119642A1
(en)
|
2016-03-15 |
2019-04-25 |
Children's Medical Center Corporation |
Methods and compositions relating to hematopoietic stem cell expansion
|
CA3020281A1
(en)
*
|
2016-04-06 |
2017-10-12 |
The Regents Of The University Of Michigan |
Monofunctional intermediates for ligand-dependent target protein degradation
|
WO2017191274A2
(en)
|
2016-05-04 |
2017-11-09 |
Curevac Ag |
Rna encoding a therapeutic protein
|
WO2017197051A1
(en)
|
2016-05-10 |
2017-11-16 |
C4 Therapeutics, Inc. |
Amine-linked c3-glutarimide degronimers for target protein degradation
|
WO2017197056A1
(en)
|
2016-05-10 |
2017-11-16 |
C4 Therapeutics, Inc. |
Bromodomain targeting degronimers for target protein degradation
|
JP7009466B2
(ja)
|
2016-10-11 |
2022-02-10 |
アルビナス・オペレーションズ・インコーポレイテッド |
アンドロゲン受容体の標的分解のための化合物および方法
|
MX2019005007A
(es)
|
2016-11-01 |
2019-07-18 |
Arvinas Inc |
Protac dirigidos a la proteína tau y métodos asociados de uso.
|
KR102173464B1
(ko)
*
|
2016-12-01 |
2020-11-04 |
아비나스 오퍼레이션스, 인코포레이티드 |
에스트로겐 수용체 분해제로서의 테트라히드로나프탈렌 및 테트라히드로이소퀴놀린 유도체
|
KR102564201B1
(ko)
|
2016-12-23 |
2023-08-07 |
아비나스 오퍼레이션스, 인코포레이티드 |
급속 진행성 섬유육종 폴리펩티드의 표적화 분해를 위한 화합물 및 방법
|
EP3559006A4
(en)
|
2016-12-23 |
2021-03-03 |
Arvinas Operations, Inc. |
COMPOUNDS AND METHODS FOR TARGETED DEGRADATION OF FETAL LIVER KINASE POLYPEPTIDES
|
EP3559002A4
(en)
|
2016-12-23 |
2021-02-17 |
Arvinas Operations, Inc. |
CHEMERICAL MOLECULES TARGETING EGFR PROTEOLYSIS AND RELATED METHODS OF USE
|
US11191741B2
(en)
|
2016-12-24 |
2021-12-07 |
Arvinas Operations, Inc. |
Compounds and methods for the targeted degradation of enhancer of zeste homolog 2 polypeptide
|
EP3573977A4
(en)
|
2017-01-26 |
2020-12-23 |
Arvinas Operations, Inc. |
EESTROGEN RECEPTOR PROTEOLYSIS MODULATORS AND RELATED METHOD OF USE
|
CA3050309A1
(en)
|
2017-01-31 |
2018-08-09 |
Arvinas Operations, Inc. |
Cereblon ligands and bifunctional compounds comprising the same
|
CN106932576A
(zh)
|
2017-03-22 |
2017-07-07 |
山东大学深圳研究院 |
一种人调节性t细胞的免疫抑制功能的检测方法
|
TWI793151B
(zh)
*
|
2017-08-23 |
2023-02-21 |
瑞士商諾華公司 |
3-(1-氧異吲哚啉-2-基)之氫吡啶-2,6-二酮衍生物及其用途
|
BR112020007576A2
(pt)
*
|
2017-10-18 |
2020-09-24 |
Novartis Ag |
composições e métodos para degradação de proteína seletiva
|
KR20210018199A
(ko)
|
2018-03-26 |
2021-02-17 |
씨4 테라퓨틱스, 인코포레이티드 |
이카로스의 분해를 위한 세레블론 결합제
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|