PT3536685T - Compostos bicíclicos de heteroarilo ou arilo fusionados e a sua utilização como inibidores de irak4 - Google Patents

Compostos bicíclicos de heteroarilo ou arilo fusionados e a sua utilização como inibidores de irak4

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Publication number
PT3536685T
PT3536685T PT191577899T PT19157789T PT3536685T PT 3536685 T PT3536685 T PT 3536685T PT 191577899 T PT191577899 T PT 191577899T PT 19157789 T PT19157789 T PT 19157789T PT 3536685 T PT3536685 T PT 3536685T
Authority
PT
Portugal
Prior art keywords
bicyclic
fused heteroaryl
aryl compounds
irak4 inhibitors
irak4
Prior art date
Application number
PT191577899T
Other languages
English (en)
Original Assignee
Pfizer
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Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PT3536685T publication Critical patent/PT3536685T/pt

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    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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