PT2900230T - Compostos para o tratamento de obesidade e métodos de utilização dos mesmos - Google Patents
Compostos para o tratamento de obesidade e métodos de utilização dos mesmosInfo
- Publication number
- PT2900230T PT2900230T PT13773562T PT13773562T PT2900230T PT 2900230 T PT2900230 T PT 2900230T PT 13773562 T PT13773562 T PT 13773562T PT 13773562 T PT13773562 T PT 13773562T PT 2900230 T PT2900230 T PT 2900230T
- Authority
- PT
- Portugal
- Prior art keywords
- obesity
- compounds
- treatment
- methods
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2264—Obesity-gene products, e.g. leptin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261706153P | 2012-09-27 | 2012-09-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2900230T true PT2900230T (pt) | 2018-11-26 |
Family
ID=49304418
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT13773562T PT2900230T (pt) | 2012-09-27 | 2013-09-26 | Compostos para o tratamento de obesidade e métodos de utilização dos mesmos |
Country Status (21)
| Country | Link |
|---|---|
| US (6) | US9968575B2 (enExample) |
| EP (3) | EP3434268B1 (enExample) |
| JP (2) | JP6480864B2 (enExample) |
| CN (3) | CN104822374A (enExample) |
| AU (3) | AU2013323528B2 (enExample) |
| BR (1) | BR112015006848A2 (enExample) |
| CA (2) | CA2886393C (enExample) |
| CY (1) | CY1121166T1 (enExample) |
| DK (1) | DK2900230T3 (enExample) |
| ES (1) | ES2696626T3 (enExample) |
| HR (1) | HRP20181879T1 (enExample) |
| HU (1) | HUE040496T2 (enExample) |
| LT (1) | LT2900230T (enExample) |
| PL (1) | PL2900230T3 (enExample) |
| PT (1) | PT2900230T (enExample) |
| RS (1) | RS58010B1 (enExample) |
| RU (2) | RU2650646C2 (enExample) |
| SI (1) | SI2900230T1 (enExample) |
| SM (1) | SMT201800604T1 (enExample) |
| TR (1) | TR201815668T4 (enExample) |
| WO (1) | WO2014052583A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104822374A (zh) | 2012-09-27 | 2015-08-05 | 儿童医学中心公司 | 用于治疗肥胖症的化合物和其使用方法 |
| AU2015235979B2 (en) * | 2014-03-26 | 2019-05-02 | The Children’s Medical Center Corporation | Celastrol and derivatives for the treatment of obesity |
| WO2015153933A1 (en) * | 2014-04-03 | 2015-10-08 | The Children's Medical Center Corporation | Hsp90 inhibitors for the treatment of obesity and methods of use thereof |
| CN105985401B (zh) * | 2015-02-16 | 2020-10-09 | 上海华拓医药科技发展有限公司 | 一种雷公藤红素衍生物、其制备方法及用途 |
| WO2017070615A1 (en) * | 2015-10-23 | 2017-04-27 | Erx Pharmaceuticals, Inc. | Analogs of celastrol |
| CN106905404B (zh) * | 2017-01-13 | 2019-08-27 | 广东工业大学 | 熊果酸衍生物及其制备方法和应用 |
| CN116133656A (zh) * | 2021-09-09 | 2023-05-16 | 君德(新加坡)实验室有限公司 | 含脂肪酶抑制剂的高吸收性水凝胶 |
| KR102470686B1 (ko) * | 2022-06-07 | 2022-11-23 | 서울대학교산학협력단 | 디메틸제일아스테럴을 포함하는 대사성 질환 예방 또는 치료용 약학 조성물 |
| CN119431489A (zh) * | 2024-11-13 | 2025-02-14 | 肇源县总医院 | 一种雷公藤红素衍生物及其制备方法 |
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|---|---|---|---|---|
| ZA791659B (en) | 1978-04-17 | 1980-04-30 | Ici Ltd | Process and apparatus for spraying liquid |
| GB8504253D0 (en) | 1985-02-19 | 1985-03-20 | Ici Plc | Electrostatic spraying apparatus |
| US4938763B1 (en) | 1988-10-03 | 1995-07-04 | Atrix Lab Inc | Biodegradable in-situ forming implants and method of producing the same |
| MY107937A (en) | 1990-02-13 | 1996-06-29 | Takeda Chemical Industries Ltd | Prolonged release microcapsules. |
| US6309853B1 (en) | 1994-08-17 | 2001-10-30 | The Rockfeller University | Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof |
| US6350730B1 (en) | 1994-08-17 | 2002-02-26 | The Rockefeller University | OB polypeptides and modified forms as modulators of body weight |
| US6001968A (en) | 1994-08-17 | 1999-12-14 | The Rockefeller University | OB polypeptides, modified forms and compositions |
| US6429290B1 (en) | 1994-08-17 | 2002-08-06 | The Rockefeller University | OB polypeptides, modified forms and derivatives |
| US5827734A (en) | 1995-01-20 | 1998-10-27 | University Of Washington | Materials and methods for determining ob protein in a biological sample |
| US5552524A (en) | 1995-01-31 | 1996-09-03 | Eli Lilly And Company | Anti-obesity proteins |
| US5521283A (en) | 1995-01-31 | 1996-05-28 | Eli Lilly And Company | Anti-obesity proteins |
| US5552522A (en) | 1995-01-31 | 1996-09-03 | Eli Lilly And Company | Anti-obesity proteins |
| US5532336A (en) | 1995-01-31 | 1996-07-02 | Eli Lilly And Company | Anti-obesity proteins |
| US5552523A (en) | 1995-01-31 | 1996-09-03 | Eli Lilly And Company | Anti-obesity proteins |
| AU6028396A (en) | 1995-06-07 | 1996-12-30 | Amgen, Inc. | Ob protein compositions and method |
| CZ416797A3 (cs) | 1995-06-30 | 1998-06-17 | Eli Lilly And Company | Použití leptinu nebo leptonových mimetik pro výrobu léčiv pro léčení nebo prevenci diabetes mellitus a kompozice s jeho obsahem |
| MX9801159A (es) | 1995-08-17 | 1998-05-31 | Amgen Inc | Metodos de reduccion o para mantener los niveles reducidos de lipidos en la sangre usando composiciones de proteina ob. |
| US5650167A (en) * | 1995-11-16 | 1997-07-22 | Dawa Incorporated | Method and composition for treating hepatitis B |
| CA2236163A1 (en) | 1995-11-22 | 1997-05-29 | Amgen Inc. | Methods of increasing lean tissue mass using ob protein compositions |
| US6936439B2 (en) | 1995-11-22 | 2005-08-30 | Amgen Inc. | OB fusion protein compositions and methods |
| US20030040467A1 (en) | 1998-06-15 | 2003-02-27 | Mary Ann Pelleymounter | Ig/ob fusions and uses thereof. |
| WO1997038014A1 (en) | 1996-04-04 | 1997-10-16 | Amgen Inc. | Fibulin pharmaceutical compositions and related methods |
| EP1001768A1 (en) | 1996-08-30 | 2000-05-24 | Amgen Inc. | Methods of increasing sensitivity of an individual to ob protein by upregulating ob protein receptor |
| HUP9904023A3 (en) | 1996-09-20 | 2002-01-28 | Hoechst Ag | Use of leptin antagonists for treating insulin resistance in type ii diabetes |
| DK0839525T3 (da) | 1996-10-31 | 2004-11-29 | Takeda Pharmaceutical | Præparat med forlænget frigivelse |
| US5880116A (en) * | 1996-12-13 | 1999-03-09 | Neurocal International | Use of celastrol to treat alzheimer's disease |
| DK0954588T3 (da) | 1996-12-20 | 2007-05-14 | Amgen Inc | OB fusionsprotein-sammensætninger og fremgangsmåder |
| HU226175B1 (en) | 1997-04-17 | 2008-06-30 | Amgen Inc | Human ob protein suspension, process for producing thereof and use for production of pharmaceutical composition |
| KR20010013414A (ko) | 1997-06-06 | 2001-02-26 | 피터 기딩스 | 당뇨병의 치료를 위한 렙틴 길항제의 용도 |
| US7052678B2 (en) | 1997-09-15 | 2006-05-30 | Massachusetts Institute Of Technology | Particles for inhalation having sustained release properties |
| US6541033B1 (en) | 1998-06-30 | 2003-04-01 | Amgen Inc. | Thermosensitive biodegradable hydrogels for sustained delivery of leptin |
| EP1107793B1 (en) | 1998-08-10 | 2004-10-27 | Amgen Inc. | Dextran-leptin conjugates, pharmaceutical compositions and related methods |
| WO2000020872A1 (en) | 1998-10-02 | 2000-04-13 | Amgen Inc. | Method to determine a predisposition to leptin treatment |
| US6420339B1 (en) | 1998-10-14 | 2002-07-16 | Amgen Inc. | Site-directed dual pegylation of proteins for improved bioactivity and biocompatibility |
| WO2000047741A1 (en) | 1999-02-12 | 2000-08-17 | Amgen Inc. | Glycosylated leptin compositions and related methods |
| EP1444516B1 (en) | 2001-10-22 | 2010-07-21 | Amgen, Inc. | Use of leptin for treating human lipoatrophy and method of determining predisposition to said treatment |
| US8486457B2 (en) * | 2002-10-21 | 2013-07-16 | Metaproteomics, Llc. | Compositions that treat or inhibit pathological conditions associated with inflammatory response |
| WO2004039832A2 (en) | 2002-10-31 | 2004-05-13 | Albany Medical College | Leptin-related peptides |
| RU2346688C2 (ru) * | 2002-12-06 | 2009-02-20 | Фиброген, Инк. | Регулирование содержания жира |
| EP1715539B1 (en) | 2004-01-16 | 2012-11-07 | Mitsubishi Materials Corporation | Separator for fuel cell, method of producing separator, and solid oxide fuel cell |
| US20060253100A1 (en) * | 2004-10-22 | 2006-11-09 | Medtronic, Inc. | Systems and Methods to Treat Pain Locally |
| AU2006300637C1 (en) | 2005-09-30 | 2010-07-01 | Morinaga Milk Industry Co., Ltd. | Agent for improving insulin resistance |
| CA2628193C (en) | 2005-11-01 | 2012-08-14 | The Regents Of The University Of Michigan | Novel 1,4-benzodiazepine-2,5-diones with therapeutic properties |
| US20090131384A1 (en) | 2006-03-22 | 2009-05-21 | Syndexa Pharmaceuticals Corporation | Compounds and methods for treatment of disorders associated with er stress |
| US20110263693A1 (en) * | 2006-03-31 | 2011-10-27 | Dana-Farber Cancer Institute, Inc. | Celastrol, gedunin, and derivatives thereof as hsp90 inhibitors |
| TW200824678A (en) | 2006-08-11 | 2008-06-16 | Combinatorx Inc | Methods and compositions for the treatment of neurodegenerative disorders |
| JPWO2008020622A1 (ja) * | 2006-08-17 | 2010-01-07 | 杏林製薬株式会社 | 新規なチエノ[2,3−d]ピリミジン化合物 |
| WO2008063513A2 (en) * | 2006-11-13 | 2008-05-29 | Trustees Of Columbia University In The City Of New York | Selective proteasome inhibitors for treating diabetes |
| CN101279995A (zh) * | 2007-04-03 | 2008-10-08 | 烟台靶点药物研究有限公司 | 一种雷公藤红素盐及其制备方法与用途 |
| US7776894B2 (en) | 2007-08-17 | 2010-08-17 | Burnham Institute For Medical Research | Compositions and methods for inhibiting growth and metastasis of melanoma |
| WO2009064298A1 (en) * | 2007-11-14 | 2009-05-22 | Amylin Pharmaceuticals, Inc. | Methods for treating obesity and obesity related diseases and disorders |
| CN101434635B (zh) * | 2007-11-16 | 2012-05-16 | 上海华拓医药科技发展股份有限公司 | 一类具抗肿瘤活性的水溶性酚性三萜化合物及其制备方法 |
| WO2009067245A2 (en) * | 2007-11-20 | 2009-05-28 | University Of Florida Research Foundation, Inc. | Compositions and methods for tissue repair |
| US20090203605A1 (en) * | 2008-02-01 | 2009-08-13 | The Scripps Research Institute | Methods For Treating A Condition Characterized By Dysfunction In Protein Homeostasis |
| CN101352444A (zh) * | 2008-09-11 | 2009-01-28 | 中国科学院广州生物医药与健康研究院 | 雷公藤红素在制药中的新应用 |
| US9132108B2 (en) | 2009-04-17 | 2015-09-15 | Hiroshima University | Pharmaceutical composition for ameliorating and/or preventing leptin resistance, and use thereof |
| CN101704874A (zh) * | 2009-11-26 | 2010-05-12 | 中国药科大学 | 五环三萜及其衍生物的二甲双胍盐、其制备方法及医药用途 |
| JP5990160B2 (ja) | 2010-04-12 | 2016-09-07 | リアタ ファーマシューティカルズ インコーポレイテッド | 抗酸化炎症モジュレーターを使用して肥満を処置する方法 |
| CN101805390B (zh) | 2010-04-13 | 2012-07-18 | 暨南大学 | 一种雷公藤红素衍生物及其用途 |
| CN102309494A (zh) * | 2010-07-01 | 2012-01-11 | 嘉兴学院 | 扁蒴藤素作为炎性细胞因子抑制剂的医药用途 |
| EP2609108B1 (en) | 2010-08-23 | 2015-12-16 | Suzhou NeuPharma Co., Ltd. | Certain chemical entities, compositions, and methods |
| US20130184272A1 (en) * | 2010-09-17 | 2013-07-18 | Takeda Pharmaceutical Company Limited | Diabetes therapeutic agent |
| KR101180387B1 (ko) | 2011-11-21 | 2012-09-10 | 동국대학교 산학협력단 | 엣지 추출을 위한 이미지 센서 및 이를 이용한 엣지 이미지 생성 방법. |
| BR112014029301A2 (pt) | 2012-05-25 | 2017-07-25 | Berg Llc | métodos de tratamento de síndrome metabólica através de modulação da proteína choque térmico (hsp) 90-beta |
| CN104822374A (zh) * | 2012-09-27 | 2015-08-05 | 儿童医学中心公司 | 用于治疗肥胖症的化合物和其使用方法 |
| CN103524592B (zh) | 2013-09-27 | 2015-08-05 | 安徽医科大学 | 一种雷公藤红素衍生物、该衍生物的生物盐及其制备方法与用途 |
| US9601471B2 (en) | 2015-04-23 | 2017-03-21 | Apple Inc. | Three layer stack structure |
-
2013
- 2013-09-26 CN CN201380061929.9A patent/CN104822374A/zh active Pending
- 2013-09-26 HU HUE13773562A patent/HUE040496T2/hu unknown
- 2013-09-26 PT PT13773562T patent/PT2900230T/pt unknown
- 2013-09-26 TR TR2018/15668T patent/TR201815668T4/tr unknown
- 2013-09-26 CN CN202010540739.7A patent/CN111529535A/zh active Pending
- 2013-09-26 EP EP18181547.3A patent/EP3434268B1/en active Active
- 2013-09-26 RU RU2015115696A patent/RU2650646C2/ru active
- 2013-09-26 DK DK13773562.7T patent/DK2900230T3/en active
- 2013-09-26 JP JP2015534652A patent/JP6480864B2/ja active Active
- 2013-09-26 CN CN202010540726.XA patent/CN111529534A/zh active Pending
- 2013-09-26 RS RS20181365A patent/RS58010B1/sr unknown
- 2013-09-26 ES ES13773562T patent/ES2696626T3/es active Active
- 2013-09-26 LT LTEP13773562.7T patent/LT2900230T/lt unknown
- 2013-09-26 US US14/431,412 patent/US9968575B2/en active Active
- 2013-09-26 BR BR112015006848A patent/BR112015006848A2/pt not_active Application Discontinuation
- 2013-09-26 CA CA2886393A patent/CA2886393C/en active Active
- 2013-09-26 SI SI201331170T patent/SI2900230T1/sl unknown
- 2013-09-26 RU RU2018112067A patent/RU2768868C2/ru active
- 2013-09-26 HR HRP20181879TT patent/HRP20181879T1/hr unknown
- 2013-09-26 CA CA3030272A patent/CA3030272C/en active Active
- 2013-09-26 AU AU2013323528A patent/AU2013323528B2/en active Active
- 2013-09-26 EP EP22168909.4A patent/EP4082541A1/en active Pending
- 2013-09-26 SM SM20180604T patent/SMT201800604T1/it unknown
- 2013-09-26 WO PCT/US2013/061911 patent/WO2014052583A1/en not_active Ceased
- 2013-09-26 EP EP13773562.7A patent/EP2900230B1/en active Active
- 2013-09-26 PL PL13773562T patent/PL2900230T3/pl unknown
-
2016
- 2016-10-21 AU AU2016247206A patent/AU2016247206B2/en active Active
-
2017
- 2017-07-07 US US15/644,247 patent/US9925161B2/en active Active
-
2018
- 2018-02-28 US US15/908,571 patent/US10653654B2/en active Active
- 2018-11-01 AU AU2018256619A patent/AU2018256619B2/en not_active Ceased
- 2018-11-08 CY CY20181101181T patent/CY1121166T1/el unknown
-
2019
- 2019-02-08 JP JP2019021437A patent/JP6743211B2/ja active Active
-
2020
- 2020-04-28 US US16/860,232 patent/US11045439B2/en active Active
-
2021
- 2021-05-21 US US17/326,944 patent/US12064408B2/en active Active
-
2024
- 2024-07-09 US US18/767,788 patent/US20250161252A1/en active Pending
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