PT2814849T - Processo de fabrico para derivados de ciclodextrina - Google Patents

Processo de fabrico para derivados de ciclodextrina

Info

Publication number
PT2814849T
PT2814849T PT137488045T PT13748804T PT2814849T PT 2814849 T PT2814849 T PT 2814849T PT 137488045 T PT137488045 T PT 137488045T PT 13748804 T PT13748804 T PT 13748804T PT 2814849 T PT2814849 T PT 2814849T
Authority
PT
Portugal
Prior art keywords
manufacturing process
cyclodextrin derivatives
cyclodextrin
derivatives
manufacturing
Prior art date
Application number
PT137488045T
Other languages
English (en)
Inventor
R Matos Jose
Original Assignee
Cydex Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cydex Pharmaceuticals Inc filed Critical Cydex Pharmaceuticals Inc
Publication of PT2814849T publication Critical patent/PT2814849T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B41/00—Formation or introduction of functional groups containing oxygen
    • C07B41/04—Formation or introduction of functional groups containing oxygen of ether, acetal or ketal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B45/00—Formation or introduction of functional groups containing sulfur
    • C07B45/02—Formation or introduction of functional groups containing sulfur of sulfo or sulfonyldioxy groups
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00049—Controlling or regulating processes
    • B01J2219/00164—Controlling or regulating processes controlling the flow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00049—Controlling or regulating processes
    • B01J2219/00164—Controlling or regulating processes controlling the flow
    • B01J2219/00166—Controlling or regulating processes controlling the flow controlling the residence time inside the reactor vessel
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00049—Controlling or regulating processes
    • B01J2219/00182—Controlling or regulating processes controlling the level of reactants in the reactor vessel
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00049—Controlling or regulating processes
    • B01J2219/00245—Avoiding undesirable reactions or side-effects
PT137488045T 2012-02-15 2013-02-14 Processo de fabrico para derivados de ciclodextrina PT2814849T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261599156P 2012-02-15 2012-02-15

Publications (1)

Publication Number Publication Date
PT2814849T true PT2814849T (pt) 2020-03-04

Family

ID=48984719

Family Applications (2)

Application Number Title Priority Date Filing Date
PT192195923T PT3702374T (pt) 2012-02-15 2013-02-14 Processo de fabrico para derivados de ciclodextrina
PT137488045T PT2814849T (pt) 2012-02-15 2013-02-14 Processo de fabrico para derivados de ciclodextrina

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT192195923T PT3702374T (pt) 2012-02-15 2013-02-14 Processo de fabrico para derivados de ciclodextrina

Country Status (11)

Country Link
US (4) US9751957B2 (pt)
EP (3) EP4083075A1 (pt)
JP (4) JP6508944B2 (pt)
CN (1) CN104271605B (pt)
DK (2) DK3702374T3 (pt)
ES (1) ES2774901T3 (pt)
HK (1) HK1205157A1 (pt)
HU (1) HUE058834T2 (pt)
PL (2) PL2814849T3 (pt)
PT (2) PT3702374T (pt)
WO (1) WO2013123254A1 (pt)

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CA2865950C (en) * 2012-02-28 2016-12-20 Cydex Pharmaceuticals, Inc. Alkylated cyclodextrin compositions and processes for preparing and using the same
EP2838558A1 (en) * 2012-04-16 2015-02-25 Regeneron Pharmaceuticals, Inc. Methods for treating or preventing influenza virus infection by administering a serine protease inhibitor
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CN103694376B (zh) * 2014-01-10 2016-04-13 凯莱英医药集团（天津）股份有限公司 一种制备磺丁基醚-β-环糊精的方法
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JP6787881B2 (ja) * 2014-08-15 2020-11-18 マサチューセッツ インスティテュート オブ テクノロジー 有効医薬品原料を含む化学生成物を合成するためのシステムおよび方法
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EP3359578A4 (en) * 2015-10-07 2019-05-15 UTI Limited Partnership MULTIFUNCTIONAL POLYANIONIC CYCLODEXTRIN DENDRIMERS
CN106749770A (zh) * 2015-11-20 2017-05-31 天津市通航科技有限公司 一种微波辐射/碱耦合制备不同取代度磺丁基醚-β-环糊精的方法
US11185839B2 (en) 2016-05-02 2021-11-30 Massachusetts Institute Of Technology Reconfigurable multi-step chemical synthesis system and related components and methods
JP6907305B2 (ja) 2016-09-20 2021-07-21 イングラム マイクロ インコーポレーテッド 地域化されていない行の自動検出、修正、及び翻訳方法
CN108034010A (zh) * 2017-12-29 2018-05-15 山东滨州智源生物科技有限公司 一种羟丙基环糊精的绿色制备方法
WO2019147755A1 (en) * 2018-01-26 2019-08-01 AL Pharma, Inc. Manufacturing and packaging of a sterile drug product
US20230357451A1 (en) * 2020-09-24 2023-11-09 Cydex Pharmaceuticals, Inc. Alkylated cyclodextrin compositions and processes for preparing and using the same
WO2023023648A1 (en) * 2021-08-19 2023-02-23 Haus Bioceuticals, Inc. Compositions and methods for increasing bioavailability using cyclodextrin modification
CN114262393A (zh) * 2021-12-29 2022-04-01 山东滨州智源生物科技有限公司 一种分子印迹技术去除磺丁基倍他环糊精钠中的1,4-丁烷磺内酯的方法
CN114369177A (zh) * 2021-12-31 2022-04-19 贵州省欣紫鸿药用辅料有限公司 一种采用管道反应器制备磺丁基醚-β-环糊精的方法

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